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Results for “brain structure”

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At least 55 records · Page 3Linked to original sources
PubMedDate not supplied

Synchronization of spontaneous activity of skeletal muscle, autonomic nerves, and brain structures in cats.

Acute and chronic experiments with recording of electrical activity of skeletal muscle, autonomic nerves, and some brain formations were performed on cats. Spectral correlation analysis showed that the spatial synchronization of electrical activity for the autonomic nerves and brain formations within the frequency range of 25--35 Hz, revealed by previous investigations, extends also to skeletal muscle. It is postulated that the presence of a widespread rhythm of 25--35 Hz is a factor facilitating the transmission of influences in the nervous system through frequency potentiation of synaptic action.

Animals↗
PubMed1979

[Drug-induced influence of the GABA-fluorescence in rat brain structures with some comments on the chemistry of the reaction (author's transl)].

1. GABA was demonstrated in rat brain in fluorescence histochemistry. The alteration by application of submaximal doses of drugs of the distribution and intensity of the transmitter fluorescence was studied in hippocampus and cerebellum. 2. Isonicotinic acid hydrazide and Penicillamine leads to a distinct grain formation and diminishing of the fluorescence product, normally appearing homogenous. These effects are considered to reflect an enzyme (GAD) inhibition. 3. By Cycloserine a distinct increase of the GABA fluorescence is effected, presumably by inhibiting GABA-transaminase-activity. 4. Chloropromazine causes diminishing, grain formation and dislocation as well of the fluorescent product, supposedly due to an affection of the membrane binding properties of GABA. 5. Hypotheses concerning the chemical events of the GABA-reaction are worded.

Animals↗
PubMed1977

[Effect of micropolarization of focal and extrafocal brain structures on experimental epilepsy].

The influence of micropolarization (MCP, 0.05-0.75 muA) was studied in chronic experiments on rabbits with epileptogenic foci provoked by penicillin (doses of 500 and 1000 U) injection into the motor cortex. A single MCP of extrafocal structure (the corpus calossum, nucleus caudatus) and the site of the focus inhibited the development of seizure reactions. Numerous MCP of the focus facilitated the seizure reactions. These effects may be explained not only by the specific role of the structures studied in the processes of the formation and propagation of the excitation, their initial functional state, but also by the dependence of the activity of these structures on the MCP regimen.

Animals↗
PubMedDate not supplied

[Synaptic reactions of sensomotor cortex neurons to stimulation of emotionally significant brain structures].

The study deals with synaptic and spike responses of neurones in the rat sensorimotor cortex to stimulation of the lateral and medial hypothalamus, locus coeruleus and raphe nuclei. The activity of 57 neurones was recorded, 41 of them intracellularly and quasi-intracellularly, in response to the stimulation of sites in these structures, which were previously identified as "emotionally/ significant. No considerable differences in the effects of the stimulation of different "emotiogenic" zones were found. The stimulation parameters, differing from the "behavioural" ones by a greater strength, elicited in the majority of neurones clear post-synaptic responses, often in the form of EPSP-IPSP. Latencies of the responses varied from 3 to 80 msec. The most stable and pronounced responses were obtained to the stimulation of the lateral hypothalamus. No significant correlations of the latencies of the responses to the stimulation of different "emotiogenic" structures were found.

Animals↗
PubMed1977

[Use of disulfiram in a histochemical study of the influence of different stimuli on the concentration of noradrenaline in brain structures].

With the help of the histochemical fluorescence method the changes in noradrenaline fluorescence of nuc. septi lateralis, nuc. interstitialis striae terminalis and nuc. preoticus medialis during conditioning and unconditioned stimulation were studied. In 135 disulfiram pretreated rats the depletion of noradrenaline fluorescence in the investigated structures was found after electro-stimulation of feet during 5 min., 1 and 2 hours, open-field behavior and reproduction of a conditioned avoidance response. Twelve hours after disulphiram administration the suppression of the open-field behavior and reproduction of the conditioned avoidance response as well as the depletion of noradrenaline fluorescence in the investigated structures were detected.

Animals↗
PubMedDate not supplied

[Effect of chronic ethanol consumption on the thyroxine hydroxylase activity of various brain structures in rats].

The effect of chronic (8-week long) 5 percent-ethanol consumption on the activity of tyrosine hydroxylase on the rat brain hypothalamus, striatum and midbrain was studied. In rats with strong ethanol prefence the enzyme activity was found to increase by 65-86 percent in the hypothalamus and to diminish by 52-68 percent and 29-68 percent in the midbrain and striatum, respectively. In rats with weak ethanol preference the enzyme activity in the brain striatum and midbrain remained unchanged, while in the hypothalamus it decreased by 25-40 percent. Chronic ethanol consumption had no effect on the inhibition of the enzyme activity neither by dopamine (8.0 X10(-4)M), nor tyrosine (in an inhibitory concentration of 3.7X(10(-4)M).

Animals↗