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PubMed2000

Vulvitis circumscripta plasmacellularis mimicking child abuse.

Vulvitis circumscripta plasmacellularis (VCP) is a rare, benign vulvar disorder that is typically described in adult women. Our case occurred in an 8-year-old girl. The primary diagnostic concern was sexual abuse. VCP may also mimic lichen sclerosus, extramammary Paget's disease, pemphigus vulgaris, fixed drug eruption, squamous cell carcinoma, candidiasis, allergic contact dermatitis, and herpes simplex infection. Evaluation should include a biopsy because the histopathologic features of VCP are distinctive.

Biopsy↗

PubMed1992

[Monosymptomatic Melkersson-Rosenthal syndrome with subsequent vulvitis and perivulvitis granulomatosa].

We report on an 40-year-old woman with granulomatous facial swelling followed by vulvitis and perivulvitis granulomatosa. The characteristic histopathology with epitheloid cell granulomas was seen in samples from both the face and the vulva. By immunohistochemistry the lesions were characterized as consisting mainly of histiocytic and CD-30-positive T cells. The possible aetiology is discussed briefly.

Adult↗

PubMed2004

Are patch tests useful in plasma cell vulvitis?

OBJECTIVE: To evaluate eventual contact sensitization in 7 patients with plasma cell vulvitis (PCV). STUDY DESIGN: Seven women with PCV underwent patch tests with the Italian standard series and with additional batteries of allergens (perfumes, preservatives, emulsifiers, medicaments and corticosteroid series). RESULTS: One patient experienced a positive reaction t o balsam of Peru and wool alcohol. CONCLUSION: Patch testing is not normally necessary in the management of PCV. However, when a patient with PCV complains of burning or pruritus after application of topical products, patch tests could prove useful.

Adult↗

PubMed2005

Retrospective histopathologic reevaluation of 18 cases of plasma cell vulvitis.

OBJECTIVE: To determine some common histologic features in a series of plasma cell vulvitis (PCV) cases. STUDY DESIGN: In a retrospective study, 18 histologic sections, previously obtained by vulvar biopsy in women diagnosed as having PCV, were critically reevaluated by the same pathologist. RESULTS: We observed that plasma cells in the dermal infiltrate were frequently present in a high percentage. Hemosiderin deposition and epithelial atrophy were 2 other histologic parameters useful for the diagnosis of PCV. Lozenge-shaped keratinocytes were rarely observed. CONCLUSION: In our series of PCV the percentage of plasma cells seemed to be the most important parameter when making the diagnosis. In particular, when this percentage was > or = 50% it was a sufficient histologic parameter for a diagnosis of PCV. When the percentage was 25-50%, hemosiderin deposition and epithelial atrophy were additional histologic features helpful in diagnosing PCV. Under 25% plasma cells was nonspecific and related to the mucosal site of involvement.

Adult↗

PubMed1992

Desquamative vulvitis.

The typical appearance of inflammatory and bullous diseases may be changed when they occur on the vulva. The moist, warm, occluded environment produces a tendency for the thin skin of the vulva to erode and scar, resulting in a common final appearance often characterized by loss of the labia minora and agglutination of the clitoral hood. The most common diseases that may produce desquamative vulvitis include lichen sclerosus, lichen planus, immunobullous diseases, contact dermatitis, erythema multiforme, lupus erythematosus, and squamous cell carcinoma in situ. The differentiating characteristics and treatment of these diseases are discussed in this article.

Adult↗

PubMed1990

[Human papillomavirus (HPV) vulvitis].

Human papilloma virus vulvitis with flat elements resembling leucoplakia may be diagnosed by application of a 5% acetic acid solution and subsequent biopsy and histological examination. The condition causes irritation with dyspareumia and is so frequent that the diagnosis and initial treatment may be undertaken by the general practitioner.

Adult↗

PubMed1990

An outbreak of granulomatous vulvitis in feedlot heifers.

An unusual form of vulvitis occurred in outbreak form affecting at least 18 of a group of 35 to 40 heifers soon after their introduction to a feedlot in the western Transvaal area of the Republic of South Africa. Initially, affected animals showed a knob-like swelling of the ventral commissure of the vulva. This grew in size up to approximately 6 cm in diameter and then appeared to burst open and give rise to a granulomatous lesion. Bovine herpesvirus type-1, Moraxella bovis, Mycoplasma bovigenitalium and Mycoplasma bovis were isolated from 2 affected heifers referred for diagnostic investigation. Mycoplasma canadense was isolated from one of the heifers. Attempts to reproduce the disease by transferring an excised portion of the lesion to unaffected animals, resulted only in lesions typical of uncomplicated infectious pustular vulvovaginitis. It is proposed that that multifactorial aetiology, including synergistic pathogenic action between the organisms isolated, was responsible for this outbreak. Administration of oxytetracycline to affected animals was followed by prompt resolution of symptoms. No further outbreaks have been reported.

Animals↗

PubMed1979

Bovine granular vulvitis associated with ureaplasma infection.

A granular vulvitis syndrome associated with ureaplasma infection was first recognized in Ontario dairy herds in 1972. The acute form of the disease was characterized by a purulent vulvar discharge, an inflamed hyperemic vulvar mucosa and varying degrees of granularity. In the chronic form, there was an absence of a purulent discharge and a gradual decline in the severity of the hyperemia and granularity. Epithelial inclusion cysts were observed in the vulvar epithelium of approximately 10% of affected cows.A seasonal variation in the incidence of the disease was observed. Herd morbidities during the summer months reached a low of 37% and increased to 75% during the winter months with constant housing.When widespread in herds, the acute form of the disease had a significant effect on fertility. In four herds examined, first service conceptions dropped on average by 27%. The chronic form of the disease had a less detrimental effect on fertility with first service conceptions being reduced on average by 13%. Intrauterine infusions of a tetracycline 24 hours postbreeding were found to be of value in improving conception rates in acutely affected herds.

Animals↗

PubMed1981

[Vulvitis plasmacellularis Zoon (author's transl)].

A rare case of plasma-cell vulvitis (Zoon) is reported in a 53 years old female. The painful erythematous plaque affected parts of the vulva. After disappointing local treatment for three years repeated intralesional injections of triamcinolone improved the condition satisfactory.

Diagnosis, Differential↗

PubMed1994

Plasma cell balanitis and vulvitis (of Zoon). A study of 10 cases.

We report six cases of plasma cell balanitis and four of plasma cell vulvitis. The patients' ages ranged from 26-88 years in males and 30-60 in females. All the men were uncircumcised and presented with a discharge and erythematous lesions on the glans penis and prepuce. In females the main presenting complaints were vulvar soreness, pruritus, smarting/burning, discharge and bleeding. Two were on hormone replacement therapy, two had undergone a mastectomy for carcinoma of the breast, and one was an insulin-dependent diabetic. Another patient subsequently developed diabetes mellitus. Topical and intralesional corticosteroid preparations resulted in satisfactory improvements in all cases, male and female. Two males subsequently underwent circumcision, which was curative.

Adult↗

PubMed1993

Vulvitis and vaginitis.

Although the vulva and vagina are embryologically and histologically different, proximity results in inflammatory conditions which commonly affect both regions. Patients often confuse 'vulvitis' and 'vaginitis' in characterizing symptoms. It is the job of the clinician to recognize inflammatory conditions specific to vulva and vagina, as well as to understand that inflammatory conditions can often involve both areas. This review of recent literature does not pretend to be comprehensive. Rather, it highlights specific conditions and research questions of recent interest.

Female↗

PubMed1976

[Vulvitis due to ancylostoma duodenale (author's transl)].

There is reported about a case of vulvitis, which was resistant to usual forms of therapy. Infections as such of Candida or of Trichomonas as well as diabetes could be excluded. But there could be proved an incidence of Ancylostoma duodenale, which is nowadays more often to be observed. Adequate therapy was successful.

Adult↗

PubMed1951