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PubMed1981

[Vivisection studies on the effects of unilateral tooth extraction on growth of the skull amd masticatory musculature (author's transl)].

Following up on the 1st part of this cycle of publications, the 2nd Bulletin deals with investigations on upper and lower jaw growth in the Vietnamese belly pig after extracting all teeth as they appeared in the right half of the jaw. The results showed characteristic changes on the side of the extraction compared with the skull on the other side. They also show clearly that the effects of unilateral loss of teeth on the development of the bony part of the chewing apparatus are very local. This is made evident by analysis distances measured for the 3rd and 4th upper jaw widths and the 2nd vertical height of the bottom jaw. In contrast to other authors, we found no changes in the longitudinal and lateral development of the bottom jaw. Due to the slight degree of development of the alveolar process of the bottom jaw in the region of the 1st permanent molar, a significant reduction in surface area was found when removing the 2nd molars, which was performed usually at an early point, only in the group slaughtered after 12 months.

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PubMedDate not supplied

Noninvasive numerical vivisection of anatomic structure and function of the intact circulatory system using high temporal resolution cylindrical scanning computerized tomography.

A high temporal resolution cylindrical scanning computerized tomographic system (DSR) is being built for study of anatomic structural/functional relationships of heart, lungs, vascular anatomy, and circulatory dynamics in any region of the body. Unlike current commercial CT scanners which scan only one or, at most, a few cross sections at a time, cylindrical scanners such as the current Mayo SSDSR and upcoming DSR scan nearly 250 cross sections simultaneously. Twenty-eight or more multiplanar images over a range of 160 or more degrees of an entire rapidly moving structure such as the heart or a segment of the circulation will be recorded in periods as short as 10 msec by the DSR at 60/sec rates and stored in computer memory. The scanned volumes can then be sectioned mathematically in any direction at will, including zooming in on regions of interest to problems at hand (e.g., clinical diagnoses). Progression from biomedical investigation to practical clinical and health care uses requires development of special-purpose, readily replicable, economical (but very high speed and volume) data handling and computational devices. The ultimates overall objective is to quantitatively characterize the performance of the human cardiopulmonary and circulatory systems utilizing pertubations associated with various types of physiologic stress and congenital or acquired disease processes including neoplasia.

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