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Sarcoid ranula. Its association with wide-spread sarcoidosis.

The presence of noncaseating granulomas in salivary tissue is a specific feature of sarcoidosis. We document the case of a healthy woman who presented with a sarcoid ranula of the sublingual salivary gland without any other manifestations of the disease. This sarcoid ranula subsequently progressed to symptomatic widespread sarcoidosis in a span of 7 months. An asymptomatic sarcoid ranula may thus possibly represent a precursor to widespread sarcoidosis.

Adult↗

Surgical management of the plunging ranula: a review of seven cases.

We have treated seven patients with a plunging ranula during the past 10 years. All patients underwent surgery via a cervical approach. In two, the ranula reached the anterior neck by passing through a dehiscence in the mylohyoid muscle, while in the other five the plunging ranula passed posteriorly to the mylohyoid muscle. A pseudocyst was extirpated in each patient. Although total sublingual gland excision was not performed in two patients, no recurrence was observed in any patient. Incision of the pseudocyst facilitated subsequent procedures and decreased the incidence of transient facial paralysis. In the presence of a cervical mass without swelling of the oral floor, a cervical approach may still be the method of choice either for the first operation or for salvage surgery after recurrence subsequent to intraoral procedures. It is based on the fact that there may be ectopic sublingual glands residing on the inferior surface of the mylohyoid muscle.

Adolescent↗

Treatment of ranula in pediatric patients with intralesional injection of OK-432.

OBJECTIVE: To assess the efficacy of treatment of a ranula in children by intralesional injection of OK-432. STUDY DESIGN: Retrospective analysis of 13 cases. METHODS: Review of medical records of pediatric patients with ranula treated by OK-432 sclerotherapy from 2002 through 2005. RESULTS: Among 13 cases, 9 were completely regressed by injection therapy alone. Three cases were incompletely regressed. One case was cured by surgical excision. The follow-up duration was 6 to 46 (mean 24.3) months. Adverse effects of OK-432 injection were tolerable, and no complication was observed. CONCLUSIONS: On the basis of our experience, sclerotherapy with OK-432 was a safe and effective primary treatment for a ranula in children. Further study will be needed to conclude its long-term effectiveness.

Adolescent↗

Plunging ranula: literature review and report of three cases.

Three cases of plunging ranula are described and the literature is reviewed. In many cases, a plunging ranula is iatrogenic and follows surgery to an oral ranula. In the cases presented, the cervical swelling was associated with prolongations of sublingual gland into or through the mylohyoid muscle. All patients were cured by partial or total excision of the sublingual gland.

Adult↗

Thoracic ranula: an extremely rare case.

We present the first case of a thoracic ranula which originated from the left submandibular area extending into the subcutaneous tissue planes of the anterior chest wall. The patient had a history of surgery for a previous benign left salivary gland cyst, and presented with an enlarging mass in the anterior chest wall. This was a recurrence of a ranula, with an extension into the anterior thoracic wall. The thoracic ranula was excised, together with ipsilateral sublingual and submandibular glands, via a transcervical approach. No recurrence was detected over a 3-year post-operative follow up.

Adult↗

Hydrodissection for complete removal of a ranula.

Hydrodissection has been used in various surgical fields to facilitate excision in both routine and difficult cases. This procedure involves the injection under pressure of saline and lidocaine with 1:100,000 epinephrine into the dissection plane. Removing a ranula without rupturing it can be a tedious and time-consuming process. Therefore, we used hydrodissection to assist us in performing these procedures. To review our experience with the treatment of ranulas, we performed a retrospective study of 38 patients who had undergone hydrodissection for ranula removal between January 1996 and December 2002 at our academic tertiary care hospital. Compared with other removal techniques, we found that hydrodissection was associated with less bleeding, fewer incidents of neural and soft-tissue damage, and a lower recurrence rate. In addition to reporting our study results, we also describe our hydrodissection technique, which is relatively simple, effective, and convenient for otolaryngologists.

Adolescent↗

Pathogenesis and treatment of plunging ranulas.

Three patients with plunging ranula, two of which occurred spontaneously and one of which followed removal of the submandibular gland, were treated by excision of the sublingual gland. The sublingual gland is removed through the mouth or through a cervical submandibular incision. No dissection of the cervical ramifications associated with the ranula is undertaken, and these disappear once the source of the extravasating saliva has been removed. Results of considerable experimental work reported by others, support the concept that plunging ranulas are extravasations of saliva from the sublingual glands.

Adolescent↗

Ranula and the sublingual salivary glands.

The term "ranula" is poorly understood and is frequently applied to a variety of cystic structures in the head and neck. Ranulas classically are cysts of salivary gland origin, usually the sublingual glands, of which two varieties are described: a simple, epithelial lined cyst resulting from ductal obstruction, and a pseudocyst without epithelial lining resulting from extravasation of saliva that dissects through the tissue planes of the neck and may appear as a neck mass. Four cases are presented that illustrate the difficulties in diagnosis; treatment consists of meticulous dissection of the thin-walled sac in continuity with the excision of the sublingual glands that are the origin of these lesions.

Adult↗

Plunging ranula: clinical observations.

BACKGROUND: The plunging ranula is a relatively uncommon phenomenon which represents a mucus escape reaction occurring from disruption of the sublingual salivary gland. We present a series of 20 patients managed at Green Lane Hospital (Auckland, New Zealand) over a 9-year period. METHODS: A retrospective review of 13 patients with this condition was undertaken, and a prospective study was conducted on 7 patients. Information was collected on age, sex, ethnic origin, history of onset, predisposing factors, treatment, and outcome of treatment. RESULTS: The patients were all young adults with a median age of 31 years. The sex distribution was relatively equal, with 11 men and 9 women. All patients were Maori or Pacific Island Polynesians. Six patients gave a clear history of preceding trauma to the neck or oral cavity. Two recurrences were seen, both in patients who had had the sublingual gland excised via a cervical approach. Five patients sustained lingual nerve damage during surgery. Full function recovered in four patients, but the complication was still present in the fifth patient at 2 years, after which he was lost to follow-up. CONCLUSIONS: Plunging ranulas appear to occur with greater incidence in the Maori and Pacific Island Polynesian populations. The precise etiology of their predisposition is unknown, although local trauma or inherent mylohyoid dehiscences may play important roles. Removal of the sublingual gland via either a cervical or intraoral approach is important in the management of this condition. Excision of the pseudocyst is probably unnecessary and places surrounding structures at risk of damage, but a biopsy of the pseudocyst wall is important to confirm the diagnosis.

Adolescent↗

Recurrent plunging ranula treated with OK-432.

A 36-year-old man was admitted who had a 2-month history of swelling of the right submandibular area and the right side of the mouth floor. He had undergone operations for right plunging ranula with a lesion on the floor of the mouth twice 7 years ago. Under fluoroscopic guidance, the contents of the cyst were aspirated as much as possible and injected with the same amount of OK-432 solution (Picibanil 0.1 mg; 10 ml) twice with 3-week intervals. Examination after 6 weeks showed that the cystic mass seen before therapy had disappeared completely, and no recurrence was encountered after 1 year. We here report a case in which a successful sclerotherapy with OK-432 for recurrent plunging ranula after surgery was performed.

Adult↗

Plunging ranula.

A review of nine cases of plunging ranula reveals a prominent vascular stroma that can, in recurrent lesions, lead to the misdiagnosis of "hemangioma". In addition, this study adds to the world's literature further evidence in support of initial excision of the sublingual gland as a cause of the plunging ranula.

Adolescent↗

Squamous cell carcinoma arising in a plunging ranula.

A case report of a 36-year-old man with a plunging ranula of 15 years' duration, in which squamous cell carcinoma arose from the cyst wall, is presented. Pathogenesis and treatment of ranulas is briefly discussed.

Adult↗

Treatment of a plunging ranula with fenestration and continuous pressure.

We present a new method of fenestration and continuous pressure as a simple, effective and uninvasive procedure for the treatment of plunging ranulas. We have recently used in four female patients, aged 10-29 years old. After treatment, the patients remained symptom-free and assessment by magnetic resonance imaging (MRI) showed regression of the ranula in all cases. The procedure resulted in satisfactory healing and we advocate it as a simple and effective treatment that is better for patients than conventional treatment.

Adolescent↗

Giant ranula causing mandibular prognathism.

This is a case report of a 20-year-old man with ranula, the size of an orange, in the floor of the mouth causing mandibular prognathism with fan-shaped mandibular teeth anterior to the premolars. The tumor was extirpated. The pathogenesis, differential diagnosis and treatment of ranulas are discussed.

Adult↗

Cervical ranula.

Ranulas are mucous extravasation cysts, and usually originate from the sublingual salivary gland. They may occasionally infiltrate the tissue planes of the neck and present as a cervical tumour. The literature is reviewed, and four personal cases of cervical ranula presented. Successful treatment may be achieved in the vast majority of cases by removal of the sublingual salivary gland.

Adult↗

A rare case of an extensive plunging ranula: discussion of imaging, diagnosis, and management.

A plunging ranula is a mucous extravasation cyst appearing as a swelling in the submental and submandibular regions. We describe a rare case of massive plunging ranula involving multiple tissue spaces. A magnetic resonance imaging scan revealed the true extent of the lesion and its relationship to the surrounding structures. Other imaging techniques and diagnostic tests are discussed. The unusual course of events following surgical excision of the offending sublingual gland is presented. The relevant literature is reviewed.

Adult↗

Ex utero intrapartum treatment (EXIT) for congenital giant ranula.

UNLABELLED: Congenital giant ranula causing life-threatening upper airway obstruction is a rare condition. A well-planned ex utero intrapartum treatment (EXIT) procedure for aspiration and decompression of the cystic lesion is simple, efficacious and effective in securing a patent airway before the fetus is completely delivered, and may prevent lifelong neurodevelopmental complications associated with perinatal asphyxia in such cases. CONCLUSION: EXIT could be a life-saving procedure for congenital giant ranula.

Adult↗