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Temporal variation of radon levels in houses and implications for radon measurement strategies.

The results of continuous measurements of radon and other parameters in four buildings have been used to investigate the causes of temporal variations in radon concentration, and to assess and quantify the accuracy of different radon measurement strategies using passive detectors. The analysis showed that the four different houses had very different responses to outdoor temperature, wind speed and direction. As expected, the results from all four houses show that longer measurements allow the annual average radon level to be estimated more accurately than short measurements. In one house, which was shown to respond to the weather in a manner typical of many Northern European houses, 90 day etched track or electret measurements could provide estimates of the annual average concentration that were always within a factor of 1.5 of the true value, whereas estimates based on charcoal detectors could exceed a factor of 2 from the true value. The effect of applying seasonal correction factors was also investigated. In the typical house, applying these factors improved the accuracy of estimates of annual average radon concentration, whichever measurement technique was used. In the three less typical houses, where radon levels were influenced by wind speed and direction, the use of seasonal correction factors did not appear to be appropriate.

Air Pollution, Indoor↗

Radon monitor calibration using NIST radon emanation standards: steady flow method.

The National Institute of Standards and Technology (NIST) polyethylene-encapsulated 226Ra/222Rn emanation (PERE) standards (old SRM 4968 and new SRMs 4971, 4972, and 4973) provide precise radon emanation rate, certified to a high degree of accuracy (approximately to 2%). Two new SRM 4973 standards containing totally 1036 Bq (0.028 microCi) of 226Ra, emanate 0.114 Bq (3.08 pCi) of 222Rn per min. Air passing over such sources at a flow rate of 1 l min(-1) will have a radon concentration of 114 Bq m(-3) (3.08 pCi l(-1)). This paper describes a practical calibration system and the actual calibration verification data obtained at different flow rates, for E-PERM passive radon monitors, Femto-Tech and Alpha Guard Continuous Radon Monitors. The use of such an affordable and easy to use system by the manufacturers and users of radon measurement devices will bring uniform standards with traceability to a NIST standard source and is considered an important step in standardising radon measurement methods.

Air Pollutants, Radioactive↗

A cohort study in southern China of tin miners exposed to radon and radon decay products.

Several studies of underground miners have demonstrated that exposure to radioactive radon gas (more precisely, 222Rn and its short-lived decay products) at levels historically found in mines increases the risk of lung cancer. Because of small numbers of lung cancers, previous studies have had limited power to evaluate temporal and other characteristics of patterns of risk. Herein we report on a historical cohort study of male employees of the Yunnan Tin Corporation in southern China. The cohort consists of 17,143 workers with 175,143 person-years of observation and 981 lung cancer events. Eighty percent of the workers were employed underground and exposed to radon. The excess relative risk increased linearly with exposure, rising 0.6% per working level month (95% confidence interval = 0.4-0.8). In the mines, workers were also exposed to arsenic-containing dusts. Adjustment for arsenic exposure, a known lung carcinogen, reduced the effect of radon exposure to 0.2% per working level month (95% confidence interval = 0.1-0.2). The excess relative risk/working level month declined significantly with attained age and with radon exposure rate as measured by the cumulative working level month divided by duration of exposure. It also declined significantly with years from last exposure and with time since exposure, but these declines were consistent only after adjustment for arsenic exposure. In this cohort, 41% of the underground workers were first exposed when < 15 y old; however, lung cancer risk did not vary consistently with age at first radon exposure. A joint analysis of radon exposure and smoking status (smoker vs. nonsmoker) rejected both an additive and a multiplicative association; the relationship was consistent with an intermediate association.

Arsenic↗

Epidemiological associations among lung cancer, radon exposure and elevation above sea level--a reassessment of Cohen's county level radon study.

Inhalation of radon (222Rn) decay products by persons living in homes has been associated with increased risk of lung cancer. Some epidemiological studies have shown a positive association between radon exposure and lung cancer rates. However, a large U.S.-wide ecological study (Cohen 1995) has shown a clear inverse association between average county radon concentration in homes and average lung cancer rates in the county. Cohen's strong inverse association between radon and lung cancer is surprising since there is no plausible biological reason for an inverse causal relationship between the two. We plot the county average lung cancer rate vs. the elevation above sea level (altitude) and show an inverse association between county average lung cancer rate and elevation. The elevation used for each county is the altitude of the most populous place in the county. We postulate that the decrease in lung cancer rates with higher elevations is caused by the carcinogenic effect of higher absolute oxygen concentration in the inspired air at lower elevations. Stratifying Cohen's lung cancer vs. radon data into ten groups of counties with similar elevations removes some, but not all, of his inverse association between radon and lung cancer.

Air Pollutants, Radioactive↗

Biochemical comparison between radon effects and thermal effects on humans in radon hot spring therapy.

The radioactive and thermal effects of radon hot spring were biochemically compared under a sauna room or hot spring conditions with a similar chemical component, using the parameters that are closely involved in the clinic for radon therapy. The results showed that the radon and thermal therapy enhanced the antioxidation functions, such as the activities of superoxide dismutase (SOD) and catalase, which inhibit lipid peroxidation and total cholesterol produced in the body. Moreover the therapy enhanced concanavalin A (ConA)-induced mitogen response and increased the percentage of CD4 positive cells, which is the marker of helper T cells, and decreased the percentage of CD8 positive cells, which is the common marker of killer T cells and suppressor T cells, in the white blood cell differentiation antigen (CD8/CD4) assay. Furthermore, the therapy increased the levels of alpha atrial natriuretic polypeptide (alpha ANP), beta endorphin, adrenocorticotropic hormone (ACTH), insulin and glucose-6-phosphate dehydrogenase (G-6-PDH), and it decreased the vasopression level. The results were on the whole larger in the radon group than in the thermal group. The findings suggest that radon therapy contributes more to the prevention of life-style-related diseases related to peroxidation reactions and immune suppression than to thermal therapy. Moreover, these indicate what may be a part of the mechanism for the alleviation of hypertension, osteoarthritis (pain), and diabetes mellitus brought about more by radon therapy than by thermal therapy.

Administration, Inhalation↗

Basic study on radon effects and thermal effects on humans in radon therapy.

Because most of the diseases to which radon (222Rn) therapy is applied are related to activated oxygen, in this study the effect of the radioactivity of radon and the thermal effect were compared under a room or a hot spring condition with the same chemical component using as the parameters the activity of superoxide dismutase (SOD), which is an oxidation inhibitor, and lipid peroxide and low density lipoprotein (LDL)-cholesterol, which are closely involved in arteriosclerosis. Results show that the SOD activity was significantly increased, and the lipid peroxide and LDL-cholesterol levels were significantly decreased on days 6 and 7 of study. The results were about 2-fold larger in the radon group than in the thermo group. This suggests that the anti-oxidation function was more enhanced by radon therapy than by thermo therapy, and suggests that radon therapy may help to prevent the causes of life style-related diseases such as arteriosclerosis. These findings are important in understanding the mechanism of diseases in which radon therapy is used as treatment, and most of which are called activated oxygen-related diseases.

Administration, Inhalation↗

[A method for preparing air-radon mixtures from radon water by decompression].

The technique has been tested of intensive radon dissolving in water usable for therapeutic procedures. The gas is provided from the soil or ore radon-containing air. The dissolving occurs under artificial growth of radon concentration in gas atmosphere by its compression at the time of mixing with cooled water in accordance with classical laws of gas distribution between liquid and gas phases in closed space. Practical utilization of the above method allows preparation of therapeutic water media without radium preparations and more effective use of radon produced in radon laboratories, thus significantly reducing radon waste and environment pollution.

Air↗

Radon (222Rn) level variations on a regional scale: influence of the basement trace element (U, Th) geochemistry on radon exhalation rates.

The approach proposed in this study provides insight into the influence of the basement geochemistry on the spatial distribution of radon (222Rn) levels both at the soil/atmosphere interface and in the atmosphere. We combine different types of in situ radon measurements and a geochemical classification of the lithologies, based on 1/50,000 geological maps, and on their trace element (U, Th) contents. The advantages of this approach are validated by a survey of a stable basement area of Hercynian age, located in South Brittany (western France) and characterized by metamorphic rocks and granitoids displaying a wide range of uranium contents. The radon source-term of the lithologies, their uranium content, is most likely to be the primary parameter which controls the radon concentrations in the outdoor environment. Indeed, the highest radon levels (> or = 100 Bq m-3 in the atmosphere, > or = 100 mBq m-2 s-1 at the surface of the soil) are mostly observed on lithologies whose mean uranium content can exceed 8 ppm and which correspond to peraluminous leucogranites or metagranitoids derived from uraniferous granitoids.

France↗

Using the European Community Radon Software to estimate the individual health benefits of a domestic radon remediation programme.

Radon can be present in domestic properties at high enough levels to pose a health risk. Such levels can usually be reduced by simple means. Studies on a group of radon-remediated homes in Northamptonshire, a radon affected area, have estimated the health benefits and cost effectiveness from remediation and have shown that remediation can be justified. These assessments have been based on collective population-average risk coefficients. The advent of the European Community Radon Software (ECRS) permits the consideration of individual risk. In particular, it can take into account individual smoking habits, which significantly affect risk, as current scientific opinion is that risks from radon and smoking are multiplicative. This note indicates how the software can be used, and the usefulness of this approach.

Air Pollution, Radioactive↗

Radon and radon daughter measurements in solar buildings.

Measurements of radon and radon daughters in 11 buildings in five states, using active or passive solar heating, showed no significant excess in concentrations over the levels measured in buildings with conventional heating systems. Radon levels in two buildings using rock storage in their active solar systems exceeded the U.S. Nuclear Regulatory Commission's limit of 3 pCi/l. for continuous exposure in uncontrolled areas. In the remainder of the buildings, radon concentrations were found to be at levels considered to be normal. It appears that the slightly elevated indoor radon concentrations result from the local geological formations and from the tightening of the buildings rather than as a result of the solar heating technology.

Climate↗

Validation of a geologically based radon risk map: are the indoor radon concentrations higher in high-risk areas?

Since geographically coded information is frequently used in studies of the relationships between environmental factors and illness at the population level and by authorities for promotion of mitigation, knowledge about the validity of proxy measures is essential. This study was an evaluation of a geologically based map describing the risk for high radon levels, which was used by the municipal authorities to determine the necessity of remedial actions. Annual mean radon gas concentrations for a random sample of one-family homes selected from high-risk areas (n = 252) were compared with those of a random sample of homes from normal and low-risk areas (n = 259). No difference in geometric mean radon concentration was found between the areas, 101 Bq m(-3) and 103 Bq m(-3), respectively. The proportion of homes in each area with radon gas concentrations above the current Swedish administrative limit value for mitigation (400 Bq m(-3)) was similar, approximately 10%. We conclude that the radon risk map was unsuitable for identifying areas of concern. The findings also indicate that geologically based and geographically coded information as a proxy for human exposures can be safely used for scientific and administrative purposes only following validation.

Air Pollution, Indoor↗

Radon measurements and analysis for central Pennsylvania counties having elevated radon levels.

The U.S. EPA identified South Central Pennsylvania as a region having elevated radon levels. The thnist of this paper is to examine in some detail the TCS Industries, Inc., data base for eight Central Pennsylvania counties having a combined population of about 1.7 million people, which is 14% of the state population. TCS has been making and analyzing radon measurements since 1986. During the period 1986 to 1999 more than 125,000 measurements were recorded in the TCS data base. The data consisted of analyzed results from four subsets. Results were from mail order charcoal canisters, bulk orders from RMP certified companies for their placement, wholesales to retail vendors, and also direct home placement of canisters, track detectors, and continuous radon monitors. The data base for the eight South Central Pennsylvania counties for tile 13-y period consists of more than 27,000 screening measurements from non-duplicated addresses. The results were assembled into three studies. The locations of tile measurements were converted into individual latitude and longitude values. The data were divided into four blocks of concentrations from 740 Bq m(-3) to over 4,440 Bq m(-3). The data were plotted on computer generated maps for South Central Pennsylvania. The plots indicated both hot spots and regions of relatively uniform chronic levels of 740 to 1,480 Bq m(-3). An average value of the basement to first floor concentrations ratio was constructed from measurements made by TCS for real estate purposes. The ratio represents 1,608 sets of simultaneous measurements of basements and first floor radon values above 37 Bq m(-3). The measurements were made by trained personnel performed under tile EPA protocol for closed house conditions. The ratio was 2.3 at 1 standard deviation of 0.05 of the mean. A third study assembled all of the data into first floor radon concentrations and separately for addresses with only basement values. The average concentration data within each of the eight counties were converted into the probability of fatal lung cancers and compared with occupational risk of fatal cancers for nuclear power plant workers. This study illustrates the importance of a continuing strong measurement program in South Central Pennsylvania.

Air Pollutants, Radioactive↗

Chemical methods for removing radon and radon daughters from air.

Liquid bromine trifluoride and the solid complexes ClF(2)SbF(6), BrF(2)SbF(6), BrF(4)Sb(2)F(11), IF(4)(SbF(6))(3) and BrF(2)BiF(6) react spontaneously with radon and radon daughters at 25 degrees C, converting the radioelements to nonvolatile ions and compounds. The reagents can be used in gas-scrubbing units to remove radon and radon daughters from air. The halogen fluoride-antimony pentafluoride complexes may be suitable for purifying air in uranium mines and analyzing radon in air, since they have low dissociation pressures at 25 degrees C and are less hazardous to handle than liquid halogen fluorides.

Air Pollution, Radioactive↗

Simulation of the radon and radon progeny detection by silicon photodiodes.

The use of silicon photodiodes for field radon measurements requires the utilization of measuring cells for protection against environmental electromagnetic fields. It is very important to study and optimize the impact of geometry conditions (dimensions of the measuring cell) on the photodiode detection efficiency that can be reduced more than 10-30 times. Two models (for volume-distributed nuclides around the detector and for radon progeny deposited on the diode surface radon progeny) were applied for simulation of the photodiode detection in measuring cells of different sizes. Their use allows an optimal choice of the most appropriate cell regarding the measurement conditions. Thus, for soil gas measurements cells we use a cell of 3.6 cm in diameter by 20 cm in height; for determination of the radon exhalation rate we use a cell of 16 cm in diameter by 14 cm in height; and for measurements in dwellings and large spaces we use cells larger than 20 cm and lower than 4 cm.

Cell Size↗

Southern blot and polymerase chain reaction exon analyses of HPRT- mutations induced by radon and radon progeny.

A linear dose response was observed for radon-induced mutations at the CHO-hprt locus with an induction frequency of 1.4 x 10(-4) mutants per viable cell per gray. Mutants isolated after two levels of radon exposure were evaluated using Southern blot techniques and polymerase chain reaction (PCR) exon amplification. No significant differences in mutational spectra were detected at these two exposure levels. Of 52 radon-induced mutations, 48% sustained a gene deletion, 23% underwent a rearrangement of the banding patterns or loss of one or more exons, and 29% showed no change from the parental line. These mutants were compared with mutants produced after X irradiation (3 Gy) and with spontaneous mutants from untreated cells. The spectra of mutation types in cells treated with radon and X rays were not significantly different. In contrast, 31 spontaneous mutations exhibited a low percentage of gene deletion events (16%); most spontaneous mutants showed no change (74%); the remaining 10% were classified as alterations. In conclusion, the principal lesion seen at the CHO-hprt locus after radiation exposure is gene deletion, while the predominant class of spontaneous mutations is composed of smaller events not detectable by Southern blot or PCR exon analysis.

Animals↗

Radon exposure and lung cancer risk--Czech cohort study on residential radon.

Epidemiological evidence of lung cancer risk from radon is based mainly on studies of men employed underground in mines where exposures are relatively high in comparison to indoor exposure. Nevertheless, direct evidence of risk from residential radon is desirable. In 1990, a study was started comprising 12,000 inhabitants of an area with elevated radon concentrations. The mean level in the houses was higher than general mean of the country by a factor of five. In the period 1961-1995, a total of 173 lung cancers were observed. Comparing to nationally expected numbers (E), the observed number (O) of cases is elevated (O/E = 1.11), in contrast to generally low figures for cancers other than lung (O/E = 0.85). Lung cancer risk related to cumulative exposures experienced in the past 5-24 or 5-35 years were both significant. In relation to standard radon progeny concentration 100 Bq/m3, the excess relative risk coefficient was 0.103 (95% CI, 0.039-0.168), the value somewhat lower than findings in other indoor studies.

Air Pollutants, Radioactive↗

[Ecological protection against volley discharges of radon from the installations of radon laboratories].

The authors analyzed the amount of radon waste and decay products discharged into atmosphere from radon laboratory units. Underlying principles of the design of radon escape monitoring and protection devices are considered. Relevant rating and the parameters of the apparatus developed to considerably limit the isotopes escape are presented. The apparatus is adjusted for current devices making radon concentrates.

Absorption↗

[The radon therapy: radon inhalation spa in Kowary].

In this paper the measurements of radon-222 concentration in the air of Kowary Radon Inhalatorium in the vicinity of Jelenia Góra, Lower Silesia, Poland, performed by Radiation Protection and Radiobiology Department of National Institute of Hygiene in Warsaw, have been presented. For the measurements the integration method with the application of charcoal canisters have been used. The radon concentration was found within the very broad ranges from about 4 to 420 kBq m-3 depending of the season of the year. Basing on the radon concentration measurements during the inhalation therapy session and taking into account the equilibrium factor of 0.8 the doses to the bronchi of the patients in range from 1.2 to about 204 mSv (0.12-20.4 rem) have been assessed. The majority of patients (ca. 76%) received the doses between 115 and 204 mSv.

Administration, Inhalation↗