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Relationship of strain 19 calfhood vaccination in beef herds and brucellosis reactor rates, duration of quarantine, and number of herd tests.

Initial and cumulative reactor rates for strain 19 vaccinates and nonvaccinates were significantly (P less than 0.001) lower for beef herds containing variable proportions of vaccinates, compared with reactor rates in nonvaccinated herds. In addition, significant (P less than 0.005) reduction in cumulative incidence was observed in nonvaccinated and strain 19-vaccinated cattle as the proportion of vaccinates within the herd increased from 1 to 19%, 20 to 39%, 40 to 59%, and 60 to 100%. Duration of quarantine and number of herd tests were not reduced in herds with strain 19-vaccinated cattle. In herds released from quarantine, duration of quarantine and number of tests were positively correlated to proportion of the herd vaccinated. In nonvaccinated herds released from quarantine, effect of herd size was documented by strong positive (P = 0.042) correlation with duration of quarantine and slightly weaker correlation (P = 0.095) with number of tests.

Animals↗

[History of the concept of quarantine].

Quarantine is a concept developed by society to protect against the outbreak of contagious diseases. From its original application in the favorable context of Medieval Europe, the quarantine concept has been driven by three main currents. The first involves the personification of epidemics. Although this personification had superstitious implications and led to many excesses, it did have the merit of establishing a concrete connection between travel and outbreak of disease. The second fundamental aspect of quarantining is the existence of a social organization capable of providing the necessary infrastructure for isolation. Specialized facilities are needed and laws must be made and enforced by competent officials. The last fundamental aspect of the development of the quarantine concept is the role of science. After a long process involving better medical knowledge and international negotiations, epidemic controls has largely outgrown the early stage involving essentially local control measures. In accordance with the development of these three currents, infected individuals have been branded as curse bearers, possible criminals, and innocent victims of natural contamination. While forced quarantine is no longer practiced, several recent examples of heated debates illustrate that strong emotional feelings are still present in societies threatened by epidemic disease outbreak. Since the major responsibility for disease control now rests in their hands, physicians must take these factors into account for management of possible future epidemic crises.

Cholera↗

Accelerated development of quarantine treatments for insects on poor hosts.

The probit 9 standard for quarantine treatment efficacy (99.9968% mortality) was originally recommended for tropical fruits heavily infested with fruit flies and it centers on high mortality to achieve quarantine security. This standard may be too stringent for quarantine pests in commodities that are rarely infested or are poor hosts, The alternative treatment efficacy approach measures risk as the probability of a mating pair, gravid female, or parthenogenic individual surviving in a shipment. This will be a function of many factors including infestation rate and shipment volume. Applying the risk-based alternative treatment efficacy approach to pests on rarely infested or poor hosts will lower the number of required test insects needed for developing quarantine treatments; hence data for a quarantine treatment could be generated by testing 10,000 or fewer insects with no survivors, compared with 90,000-100,000 insects to demonstrate the traditional probit 9 efficacy. Several commodity/quarantine pest systems where this approach could be applied are discussed. This approach would save time and resources, and help farmers export their crop on a more-timely basis.

Animals↗

A plague epidemic in voluntary quarantine.

In September 1665, an outbreak of plague occurred in Eyam, a small village 10 miles west of Sheffield, in an isolated valley of Derbyshire. Eighty per cent of the population died during the 14 months of the epidemic, a greater proportion than any other community in England. When plague threatened to cause panic and desertion of the village, the vicar of Eyam persuaded the villagers to stay, and to impose a voluntary quarantine on their village, in order to avoid spreading the plague to the surrounding villages. Quarantine was strictly observed for the last five months of the epidemic, when it was at its height. A boundary about one mile in diameter was marked out around the village, and food was left at the boundary for villagers to collect. The parish register can be used to describe the natural history of this plague epidemic in quarantine; in the light of current knowledge of plague epidemiology, it shows the traditional account of the origin of the Eyam plague to be improbable. The pattern of the epidemic suggests a typical epidemic of bubonic plague with a rodent reservoir. The policy of quarantine, rightly judged as heroic, was also tragically misguided, and was probably responsible for the unparalleled mortality.

Animals↗

Survey of gastrointestinal parasitic infections in quarantined dogs in Taiwan.

Intestinal helminth and protozoan infection in the quarantined dogs in Taiwan were examined using fecal examination between January to December, 2004. Of the 376 dogs imported from 11 countries, 63 (16.8%) were found to be infected with at least one species of intestinal parasite. The parasites detected were oocysts of Isospora canis and eggs of Toxocara canis, Trichuris vulpis and hookworms. Of the 63 infected dogs, 11 were found to have a mixed infection of two different species of parasites. This paper illustrates that parasites are transmitted from one country to another through the transport of animals. Moreover, there is also a possibility of parasitic infection among quarantined dogs as well as the zoonotic potential for quarantine officers during the quarantine period.

Animals↗

Attitudes toward the use of quarantine in a public health emergency in four countries.

Countries worldwide face the threat of emerging infectious diseases. To understand the public's reaction to the use of widespread quarantine should such an outbreak occur, the Harvard School of Public Health, with the U.S. Centers for Disease Control and Prevention, undertook a survey of residents of Hong Kong, Taiwan, Singapore, and the United States. A sizable proportion of the public in each country opposed compulsory quarantine. Respondents were concerned about overcrowding, infection, and inability to communicate with family members while in quarantine. Officials will need specific plans to deal with the public's concerns about compulsory quarantine policies.

Attitude to Health↗

Quarantine in times of emergency: the scope of s 51(ix) of the Constitution.

This article explores the scope of s 51(ix) of the Constitution, the power of the Commonwealth to make laws with respect to "quarantine". While this power has sustained the Quarantine Act without a challenge since 1908, it may be that future national public health emergencies, such as epidemics or bioterrorism, will (as has happened in other countries) demand a level of federal preparedness that requires augmented public health powers at a national level. If so, will the scope of the quarantine power, as determined by the High Court, be wide enough allow the Commonwealth to implement these powers? While there is some advantage in a national approach, there is also some authority suggesting that the quarantine power could not extend to domestic public health controls. If there is uncertainty about the scope of the power, what are the options? Should there be another approach, with the States, Territories and the Commonwealth moving towards uniform legislation and co-operative arrangements?

Australia↗

Hawaiian tephritid fruit flies (Diptera): integrity of the infestation-free quarantine procedure for 'Sharwil' avocado.

In 1990, the infestation-free quarantine procedure for 'Sharwil' avocados grown in Kona, HI, was approved based on the assumption that fruits on trees are not hosts of tephritid fruit flies. In February 1992, the infestation-free quarantine procedure was suspended because of discovery of oriental fruit fly, Bactrocera dorsalis (Hendel), larval infestation in fruits on trees in certified orchards. Subsequently, an intensive field study was conducted to determine the level of tephritid fruit fly infestations in 'Sharwil' fruits. Results gathered negated two assumptions of the infestation-free quarantine procedure. First, the procedure assumed that only immature and mature green fruits are attached on trees; our data showed that, although most fruits on trees were either immature or mature green, a few ripe fruits occurred during the fruiting season. Second, the procedure assumed that mature green fruits have absolute resistance to tephritid fruit flies occurring in Hawaii; our field data showed that mature green 'Sharwil' avocados are suitable hosts of oriental fruit fly, albeit poor hosts. We present several hypotheses that may explain the failure of the infestation-free quarantine procedure for 'Sharwil' avocados. Morphological, physical, and chemical attributes of maturing 'Sharwil' fruits that may be useful in developing indices of fruit maturity and quality are also presented.

Animals↗

Generic ionizing radiation quarantine treatments against fruit flies (Diptera: Tephritidae) proposed.

Tephritid fruit flies comprise the most important group of quarantined pests of fresh produce. Most quarantine treatments of fresh agricultural commodities are directed against these pests, and considerable effort in detection, trapping, and population control is expended worldwide to prevent these pests from invading new territories. Ionizing radiation has been studied for 70 yr for its possible use as a quarantine treatment against fruit flies, but has only been applied commercially on a limited basis since 1995. The treatment has great potential and will probably be used extensively in the future as it is tolerated by more species of fruits than any other major treatment. The U.S. Department Agriculture, Animal and Plant Health Inspection Service only recently proposed allowing irradiation for fresh agricultural imports from other countries, and other countries are studying proposals to do likewise. In 1991, the International Consultative Group on Food Irradiation recommended a generic dose against all tephritid fruit flies of 150 Gy. This article examines the literature dealing with irradiation quarantine treatments against fruit flies and recommends minimum absorbed doses of 70 Gy for Anastrepha spp., 101 Gy for Bactrocera jarvisi and B. tryoni, and 150 Gy for all Tephritidae except when fruits have been stored in hypoxic atmospheres.

Animals↗

Ionizing irradiation quarantine treatment against plum curculio (Coleoptera: Curculionidae).

Plum curculio, Conotrachelus nenuphar (Herbst), is a quarantine pest of many temperate fruits, such as pomes, Malus spp.; stone fruits, Prunus spp.; and blueberries, Vaccinium spp.; in North America east of the Rocky Mountains and a small area in Utah. There are two strains, a northern univoltine one that undergoes obligate diapause as an adult and a southern multivoltine strain that usually has facultative diapause. Current quarantine treatments for shipment to areas that do not have the pest include methyl bromide fumigation and cold storage for several weeks. The cold storage treatment may not be effective against northern strain adults in diapause. The objective of this research was to develop an irradiation quarantine treatment against plum curculio. The estimated dose to kill southern strain plum curculio adults in one day is approximately 4 kGy. Diapausing northern strain plum curculios were prevented from reproducing with 40 Gy. Reproduction of southern strain plum curculios was prevented with a target dose of 80 Gy, and the dose recommended as a quarantine treatment, that would prevent adults from reproducing, is 92 Gy, the maximum absorbed dose measured when a target dose of 80 Gy was sought. At that dose, oviposition may still occur for up to 1 wk and some of the eggs may hatch, but there is no development beyond the first instar. Hosts of the plum curculio would tolerate that dose well. Immature plum curculios were prevented from reproducing with lower doses.

Animals↗

SARS outbreak in Germany 2003: workload of local health departments and their compliance in quarantine measures--implications for outbreak modeling and surge capacity?

OBJECTIVE: Public health management of severe acute respiratory syndrome epidemic must be evaluated to improve contingency planning for epidemics. METHODS: Standardized questionnaires on case management were sent to local health departments of 15 of 16 states in Germany. RESULTS: Of the 384 local health departments who received the questionnaire, 280 (72%) completed them. They reported 271 suspect or probable severe acute respiratory syndrome cases under investigation (average 4.7). The average duration of quarantine was 5.4 days. Contacts without professional activity were 2.78 times more likely to stay under 10-day quarantine than those with professional activity (CI: 0.80-9.86). Local health departments with at least one case under investigation had invested an average of 104.5 working hours. CONCLUSIONS: Our contact-case ratios may serve for planning for modeling in epidemics. We found discrepancies between local and national surveillance figures; home quarantine was frequently not applied as recommended and the burden on urban health departments was disproportionally higher. Flexibility of the national surveillance system and surge capacity for the prevention of future epidemics need improvement, particularly in urban health departments.

Disease Outbreaks↗

Risks of fish imports--the 1993 aquatic animal quarantine review.

The rapid expansion of knowledge of fish diseases and pathogens in the past decade has led to a realisation that Australian quarantine policy on fish imports, which has largely evolved on a needs basis, requires substantial revision. As a result, the Australian Quarantine and Inspection Service has commissioned a major review of quarantine policy with regard to risks of disease associated with importation of aquatic animals and their products. The review, to be managed by the Bureau of Resource Sciences, will be carried out this year.

Animals↗

Modelling potential responses to severe acute respiratory syndrome in Japan: the role of initial attack size, precaution, and quarantine.

BACKGROUND: There has been an outbreak of the severe acute respiratory syndrome (SARS) worldwide. With the use of detailed epidemiological data from other countries, this article describes the possible reason for the SARS epidemic not appearing in Japan, and simulates the impact of different control strategies that can break the transmission cycle of SARS associated coronavirus. METHOD: Mathematical modelling is used for predicting the epidemiological outcome and simultaneously for evaluating the effect of interventions on SARS. The study estimates the initial attack size that would result in failed invasion. Three different interventions have been incorporated into the public health response policies; precautionary public health measures, isolation of infected people, and quarantine of exposed humans. RESULTS: The maximum number of humans newly infected could be roughly estimated on the basis of the initial attack size, using simple formulas. It is seen that the introduction of only a few cases into certain communities would not lead easily to an epidemic. The possible trajectories of SARS epidemic depend on the levels of public health interventions as quarantine and precautionary public health measures greatly affected the transmissibility of the disease. It is shown that there exist threshold levels of interventions at which the SARS epidemic settles down. CONCLUSION: Initial attack size is one of the determinants of whether SARS can successfully invade the community or not. Two of the most effective policy procedures to prevent new infections would be to apply stringent precautionary measures and to impose quicker and more effective quarantine of the exposed populace.

Disease Outbreaks↗

"Co-operation in All Human Endeavour": quarantine and immigrant disease vectors in the 1918-1919 influenza pandemic in Winnipeg.

Unlike occurrences of other contagious diseases such as cholera and smallpox, the 1918-19 influenza pandemic did not lead to anti-immigrant backlash, the stigmatization of newcomers as disease carriers, or aggressive quarantine measures focused against immigrant groups. During influenza outbreaks in several major Canadian cities, quarantine was either rejected or was a low-priority containment measure, reluctantly and sceptically employed. Blaming immigrants during the epidemic was not considered enlightened public health practice or good disease containment strategy. Retrospective evaluation of the successes and failures of the fight against influenza concluded that coercive measures such as quarantine did more harm than good. The experience with influenza contributed to new notions of immigrant inclusion in the social body.

Canada↗

Predicting quarantine failure rates.

Preemptive quarantine through contact-tracing effectively controls emerging infectious diseases. Occasionally this quarantine fails, however, and infected persons are released. The probability of quarantine failure is typically estimated from disease-specific data. Here a simple, exact estimate of the failure rate is derived that does not depend on disease-specific parameters. This estimate is universally applicable to all infectious diseases.

Communicable Disease Control↗

Quarantine and the problem of AIDS.

Through history, quarantine has been a response not only to the mode of disease transmission, but also to popular demands for a boundary between the kind of people so diseased and the respectable people who hope to remain healthy. Efforts to control epidemics--leprosy, cholera, tuberculosis, drug addiction--through quarantine of large numbers of people have never been successful. AIDS patients share characteristics often invoked in defense of quarantine; they do have reason to fear anachronistic and unenlightened outrage.

Acquired Immunodeficiency Syndrome↗

Factors associated with the seroprevalence of pseudorabies virus in breeding swine from quarantined herds.

Strategies for the elimination of pseudorabies virus (PRV) from swine herds include test and removal, offspring segregation, and depopulation/repopulation. The prevalence of PRV in a herd is a major factor in selection of the most appropriate strategy. The purpose of the study reported here was to describe the prevalence of PRV in adult swine in PRV quarantined herds in Minnesota, and to determine herd factors associated with the seroprevalence. Questionnaires describing the health history of the herd, management practices, and design of the swine facilities were obtained from the owners of 142 quarantined herds. Blood was collected from 29 finishing pigs over the age of 4 months, up to 29 adult females, and all herd boars. Factors considered to be significant in a bivariate analysis were combined in a stepwise multiple logistic regression analysis. The prevalence of PRV-seropositive adults in each herd was bimodally distributed among the 142 herds. In 42 (30%) of the herds, none of the females tested was seropositive, which represented the lower mode. At least 90% of the adults tested were seropositive in 30 (21%) of the herds and represented the higher mode. The odds of the breeding swine of a given herd having a PRV seroprevalence of greater than or equal to 20% as compared with having a seroprevalence of less than 20% was 1.654 times higher per 50 adults in the herd, 13.550 times higher if the finishing pigs were seropositive, 2.378 times higher if sows were housed inside during gestation, and 1.481 times lower per number of years since the imposition of quarantine.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗

Considerations in receiving and quarantining laboratory rodents.

The development of increased bacteriologic and viral screening has revealed evidence of exposure to possible pathogens in animals from even the best suppliers. Because the cost in money and space to quarantine all rodents in many types of research institutions is great, and because of an increased ability to detect possible pathogens, a dilemma exists. At the same time, regulations are being implemented which, in many cases, mandate a quarantine period. In all cases, however, the professional judgement of laboratory animal medicine specialists is increasingly needed to interpret the best course of action. A proper matching of animal quality with a realistic assessment of research requirements seems the best course, with quarantine implemented where truly appropriate.

Animals↗