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Pesticide poisonings in the lawn care and tree service industries. A review of cases in the New York State Pesticide Poisoning Registry.

Although pesticides are used extensively by lawn care and tree service workers, the incidence of pesticide poisonings among this population has never been systematically assessed. This article is a review of suspected and confirmed pesticide poisonings of lawn care and tree service applicators that were reported to the New York State Pesticide Poisoning Registry from 1990 to 1993. Thirty-nine cases were identified, of which 28 satisfied the criteria for a suspected or confirmed poisoning. At the time of the poisoning, the majority of applicators reported the use of more than one class of pesticide. The most common classes of pesticide applied were organophosphates (71%) and herbicides (43%). Twenty-four cases were identified through laboratory reporting. All 24 laboratory tests had been ordered for worker surveillance. Twenty of the reported workers were symptomatic. Personal protective equipment was used routinely by 22 of the 27 applicators for whom information was available. These data suggest that pesticide exposures are occurring among a subset of the lawn care and tree service applicators, despite the reported routine use of safety measures. More rigorous evaluation of the control measures utilized in the lawn care and tree and shrub industry is warranted.

Adult↗

Surveys to assess the amount of pesticide in wool and the use of pesticides by woolgrowers in Queensland.

OBJECTIVE: To measure the amounts of pesticide residue in wool grown in Queensland between 1997 and 1999, and to describe the use of pesticides for the control of lice infestations and blowfly strike in Queensland sheep flocks. DESIGN: Pesticide residues were measured in a random sample of wool from Queensland clips offered for sale during 1998 and 1999. Information on pesticide use was obtained from a trace-back postal survey. PROCEDURE: Samples taken from wool lots were tested for the presence and amount of organophosphorus (OP), synthetic pyrethroid (SP) and insect growth regulator pesticides. A questionnaire seeking information on flock characteristics and pesticide use was sent to the manager of each flock from which a wool sample was tested. RESULTS: The mean amount of OP and SP residue was 2.0 and 0.8 mg/kg, respectively. Ninety-five and 98% of wool samples contained < 9 mg/kg and 7 mg/kg of OP and SP residues, respectively. The mean amount of cyromazine, diflubenzuron and triflumuron was 12.7, 5.8 and 13.0 mg/kg, respectively. The amounts of OP, cyromazine and triflumuron residues were greater in wool from flocks located in southern Queensland. CONCLUSION: Most (95%; 95% CI, 92-97%) Queensland wool clips grown between 1997 and 1999 meet the suggested Australian maximum acceptable residue amounts for OP and SP pesticides.

Animal Husbandry↗

Dietary intake of pesticide chemicals. Calculated daily consumption of pesticides with foods are discussed and compared with currently accepted values.

Residues of chlorinated organic pesticide chemicals were commonly found in all diet samples and all food classes within samples except beverages at a daily intake of 0.0014 mg per kilogram of body weight. Meat, fish, and poultry were the major source of pesticide residues and, when combined with dairy products, account for more than half of the intake of chlorinated organic pesticide chemicals. Fruits, garden fruits, and grain foods each accounted for about 10 percent of the intake of chlorinated pesticides. The DDT, its two analogs, dieldrin, lindane, and heptachlor epoxide account for 85 percent of the total intake of chlorinated pesticides. A single pesticide, DDT, accounts for one-third of the total. There was no statistically significant change in frequency or quantities of these compounds during this study. Frequency and quantities of the 14 additional chlorinated pesticides were too low to be meaningful.

Animals↗

Historical pesticide exposure in California using pesticide use reports and land-use surveys: an assessment of misclassification error and bias.

We used California's Pesticide Use Report (PUR) and land-use survey data to conduct a simulation study evaluating the potential consequences of misclassifying residential exposure from proximity to agricultural pesticide application in health effect studies. We developed a geographic model linking the PUR with crop location data from land-use surveys to assess the impact of exposure misclassification from simpler exposure models based solely on PUR or land-use data. We simulated the random selection of population controls recruited into a hypothetical case-control study within an agricultural region. Using residential parcel data, we derived annual exposure prevalences, sensitivity, and specificity for five pesticides and relied on the PUR plus land-use model as the "gold standard." Based on these estimates, we calculated the attenuation of prespecified true odds ratios (ORs), assuming nondifferential exposure misclassification. True ORs were severely attenuated a) when residential exposure status was based on a larger geographic area yielding higher sensitivity but low specificity for exposure, in contrast to relying on a smaller area and increasing specificity; b) for less frequently applied pesticides; and c) with increasing mobility of residents among the study population. Considerable effect estimate attenuation also occurred when we used residential distance to crops as a proxy for pesticide exposure. Finally, exposure classifications based on annual instead of seasonal summaries of PUR resulted in highly attenuated ORs, especially during seasons when applications of specific pesticides were unlikely to occur. These results underscore the importance of increasing the spatiotemporal resolution of pesticide exposure models to minimize misclassification.

Agriculture↗

An improved description of pesticide volatilization: refinement of the pesticide leaching model (PELMO).

The consideration of pesticide volatilization from soil surfaces as an integral component of pesticide fate models is of importance, especially as part of the Predicted Environmental Concentrations (PEC) models used in the registration procedures for pesticides. The Pesticide Leaching Model (PELMO), which is used in the European registration process, was modified to allow for a reliable prediction of volatilization from soil. The previous PELMO version was upgraded by improving the spatiotemporal discretization at the soil surface, improving the empirical description of temperature dependence of Henry's law constants and including increased sorption of pesticides in dry soils. Comparison of predictions with experimental findings revealed the improvements of PELMO to contribute to a more realistic reflection of measurements, particularly at initial stages of the studies. The broad range of literature values of Henry's law constants was shown to have a significant effect on predicted volatilization fluxes. As a main refinement, the tendency of pesticides toward enhanced volatilization under moist conditions was correctly calculated by the improved model. Variations between model predictions and measurements were due to a lack of experimental data on soil sorption under dry conditions and indicated the need for further calibration of the model. The description of water content in the top layer was subject to uncertainty, which was exemplified by an overestimation of soil moisture during the last days of the field study. Thus, future model improvement will be dependent on experimental support to obtain more detailed information on soil-air-water partitioning of pesticides in the top soil layer.

Forecasting↗

Report of a panel on the relationship between public exposure to pesticides and cancer. Ad Hoc Panel on Pesticides and Cancer. National Cancer Institute of Canada.

BACKGROUND: Pesticides, which by their nature are biologically active compounds, continue to raise public concern regarding their possible role as important etiologic agents in the development of human cancer. METHODS: To examine this potential role, the National Cancer Institute of Canada convened an Ad Hoc Panel on Pesticides and Cancer to examine the possible contribution of pesticide exposure, particularly in the general population, to the development of human cancer. RESULTS: The Panel focused primarily on exposure in the general population and reviewed a range of studies that addressed issues related to dietary exposure as well as incidental home and garden uses. In addition, the Panel examined the regulatory framework that exists to safeguard the public from potentially carcinogenic pesticides and also reviewed some potential benefits of pesticide use, including the availability of an abundant and low cost supply of fresh fruits and vegetables as an important strategy in the overall mitigation of cancer risk. CONCLUSIONS: The Panel concluded that it was not aware of any definitive evidence to suggest that synthetic pesticides contribute significantly to overall cancer mortality. The Panel also concluded that it did not believe that any increased intake of pesticide residues associated with increased intake of fruits and vegetables poses any increased risk of cancer. The Panel further concluded, among other things, that tobacco use continues to be the most important preventable cause of cancer and premature mortality and thus is an appropriate focus for cancer control strategy.

Environmental Exposure↗

The pesticide module of the Root Zone Water Quality Model (RZWQM): testing and sensitivity analysis of selected algorithms for pesticide fate and surface runoff.

The Root Zone Water Quality Model (RZWQM) is a one-dimensional, numerical model for simulating water movement and chemical transport under a variety of management and weather scenarios at the field scale. The pesticide module of RZWQM includes detailed algorithms that describe the complex interactions between pesticides and the environment. We have simulated a range of situations with RZWQM, including foliar interception and washoff of a multiply applied insecticide (chlorpyrifos) to growing corn, and herbicides (alachlor, atrazine, flumetsulam) with pH-dependent soil sorption, to examine whether the model appears to generate reasonable results. The model was also tested using chlorpyrifos and flumetsulam for the sensitivity of its predictions of chemical fate and water and pesticide runoff to various input parameters. The model appears to generate reasonable representations of the fate and partitioning of surface- and foliar-applied chemicals, and the sorption of weakly acidic or basic pesticides, processes that are becoming increasingly important for describing adequately the environmental behavior of newer pesticides. However, the kinetic sorption algorithms for charged pesticides appear to be faulty. Of the 29 parameters and variables analyzed, chlorpyrifos half-life, the Freundlich adsorption exponent, the fraction of kinetic sorption sites, air temperature, soil bulk density, soil-water content at 33 kPa suction head and rainfall were most sensitive for predictions of chlorpyrifos residues in soil. The latter three inputs and the saturated hydraulic conductivity of the soil and surface crusts were most sensitive for predictions of surface water runoff and water-phase loss of chlorpyrifos. In addition, predictions of flumetsulam (a weak acid) runoff and dynamics in soil were sensitive to the Freundlich equilibrium adsorption constant, soil pH and its dissociation coefficient.

Algorithms↗

Degradation of pesticides in biobeds: the effect of concentration and pesticide mixtures.

Biobeds aim to create an environment whereby any pesticide spills are retained and then degraded, thus reducing the potential for surface or groundwater contamination. Biobeds may receive high concentrations of relatively complex mixtures of pesticides. The effects of concentration and pesticide interaction on degradation rate were therefore investigated. At concentrations up to 20 times the maximum recommended application rate for isoproturon and chlorothalonil, the rate of degradation in topsoil and biomix decreased with increasing concentration. With the exception of isoproturon at concentrations above 11 mg kg(-1), degradation was quicker in biomix (a composted mixture of topsoil, compost, and wheat straw) than in topsoil. One possible explanation for faster isoproturon degradation in topsoil as compared to biomix may be that previous treatments of isoproturon applied to the field soil as part of normal agricultural practices had resulted in proliferation of microbial communities specifically adapted to use isoproturon as an energy source. Such microbial adaptation could enhance the performance of a biobed. Studies with a mixture of isoproturon and chlorothalonil showed that interactions between pesticides are possible. In biomix, the degradation of either isoproturon or chlorothalonil was unaffected by the presence of the other pesticide, whereas in topsoil, isoproturon DT(50) values increased from 18.5 to 71.5 days in the presence of chlorothalonil. These studies suggest that biobeds appear capable of treating high concentrations of more than one pesticide.

Biodegradation, Environmental↗

Distributions, associations, and partial aggregate exposure of pesticides and polynuclear aromatic hydrocarbons in the Minnesota Children's Pesticide Exposure Study (MNCPES).

The Minnesota Children's Pesticide Exposure Study (MNCPES) provides exposure, environmental, and biologic data relating to multipathway exposures of children for four primary pesticides (chlorpyrifos, malathion, diazinon, and atrazine), 14 secondary pesticides, and 13 polynuclear aromatic hydrocarbons (PAHs). Monitoring was performed on a probability-based sample of 102 children aged 3-12 in Minneapolis/St. Paul and in a nearby rural area (Goodhue and Rice counties). This paper provides estimated distributions of this population's exposures and exposure-related measurements and examines associations among the various measures via rank (Spearman) correlations. In addition, it provides some aggregate and cumulative exposure estimates for pesticides, and compares the relative intakes from inhalation and dietary ingestion. Intakes for the four primary pesticides appeared to come principally from the ingestion rather than the inhalation route; this was clearly true for chlorpyrifos but was less certain for the other three primary pesticides because of their higher degree of nondetects. Solid food rather than beverages was clearly the main contributor to the ingestion intake. Despite the dominance of the ingestion route, the urinary metabolite of chlorpyrifos exhibited a stronger association with the air measurements than with the dietary measures. Personal-air samples exhibited strong rank correlations with indoor air samples for chlorpyrifos, malathion, and diazinon (0.81, 0.51, and 0.62, respectively), while personal-air atrazine levels correlated well with outdoor levels (0.69); personal-air diazinon levels also correlated well with outdoor levels (0.67). For the PAHs, many significant associations were evident among the various air samples and for the air samples with the dust samples, especially for those compounds with consistently high percent measurable values (particularly fluoranthene, phenanthrene, and pyrene).

Child↗

Association of pesticide safety knowledge with beliefs and intentions among farm pesticide applicators.

Although a number of health hazards associated with pesticide exposure have been well documented, relatively little is known about the knowledge and health beliefs that may influence pesticide handling. This study measured knowledge levels concerning pesticide safety and precautionary handling among applicators and examined relationships between knowledge scores and intentions to use handling precautions, perceptions of pesticide safety peer norms, and perceived self-efficacy to prevent personal exposure. Telephone interviews were conducted with a randomly selected sample of 164 dairy farmers who were pesticide applicators residing in Wisconsin (response rate = 77.4%). The percentage of correct responses to 18 knowledge items ranged from 100% to 45.7%. Knowledge levels were positively related to intentions, beliefs, and self-efficacy regarding use of personal protective gear but were not significantly related to risk perceptions and peer norms concerning pesticide safety.

Adult↗

Trends in the use of pesticides and pesticide residues on Queensland wool.

OBJECTIVE: To determine the amounts of organophosphorous and synthetic pyrethroid residues on Queensland wool sampled between 1995 and 1997, and to study if pesticide use changed during the period. DESIGN: Estimated amounts of residues were obtained from a survey of Queensland wool clips and information on pesticide use was obtained from a trace-back postal survey of flock managers. PROCEDURE: Trends in amounts of residues over time were assessed using analysis of variance and simple linear regression models, and changes in pesticide use was assessed using chi 2 tests. RESULTS: Significant linear reductions in organophosphorous (P = 0.0012), synthetic pyrethroid (P = 0.0044) and total (P = 0.0002) residues were detected. The proportion of wool-growers treating for louse infestation (P = 0.0046) treating twice or more (P = 0.0006) and treating more than 4 months after shearing (P = 0.0001) decreased between 1994 and 1997. However, the proportion of growers who treated for blowfly strike (P = 0.0124) and used insect growth regulator pesticides increased (P < 0.0001). The use of handjetting to apply pesticides for blowfly strike control increased and the use of dips decreased (P < 0.0001). CONCLUSION: Residues of organophosphorous compounds and synthetic pyrethroids reduced in Queensland wool between 1994 and 1997. Although woolgrowers treated for louse infestation less, pesticide use to control blowfly strike increased. The increasing use of insect growth regulators in the industry needs to be monitored.

Animals↗

Pesticide residues in selected food commodities: results from the Danish National Pesticide Monitoring Program 1995-1996.

The paper presents results of analyses of 4182 samples collected from January 1995 to December 1996 for the Danish National Pesticide Monitoring Program. The program basis is a random sample control supplemented with a target control. The objectives of the control are to monitor consumer exposure to health hazards and to enforce national and European Community regulations. The Danish Veterinary and Food Administration is responsible for establishing methods, data manipulation, and evaluation, but actual analyses are performed at 4 regional laboratories. In addition to a description of the Danish National Pesticide Monitoring Program on food, the effects of lowering the reporting limits are discussed. Pesticides included are those in current use as well as chlorinated pesticides like lindane, DDT, and HCB, occurring in food now primarily as a result of environmental contamination. Commodities analyzed are fruits, vegetables, cereals, bran, fish, and animal products such as meat, butter, cheese, fat, and eggs. In fruits and vegetables, residues were detected in 10% of 2515 samples, with higher incidences of detection for foreign commodities. Violation rate was 0.6%. In food of animal origin, low levels of organochlorine pesticides were detected in most fish samples and in more than half of the animal product samples. However, no results exceeding maximum residue limits were found. No residues of organophosphorus pesticides were detected in the 231 meat samples analyzed.

Animals↗

A pesticide runoff model for simulating runoff losses of pesticides from agricultural lands.

An integrated modeling system was developed to predict runoff losses of pesticides from agricultural lands. The system is an integration of a mathematical model, a database system, and a geographic information system. Information on soil type, land use, land slope, watershed boundaries, precipitation, pesticide usage, as well as physical and chemical properties of pesticides have been input to a GIS, managed through a database, and used for further modeling studies. The modeling outputs were in turn put into the database, such that runoff patterns along with pesticides losses could be further simulated by using a database management system. The final results could then be visualized through GIS. The developed modeling system was applied to the Kintore Creek Watershed, Ontario, Canada, for simulating losses of atrazine from agricultural lands. A water quality monitoring project was carried out from 1988 to 1992 in the watershed to detect conditions of surface water pollution due to the use of pesticides. The modeling outputs were verified through the monitoring data, demonstrating reasonable prediction accuracy. The result indicated that the model provides an effective means for forecasting pesticide runoff from agriculture lands.

Agriculture↗

[The reporting system of acute pesticides poisoning and general situation of pesticides poisoning in China].

OBJECTIVE: To introduce the reporting system of acute pesticides poisoning and analyze epidemiologic characteristics of pesticides poisoning from reported cases in China. METHODS: Case reports in the data base of reporting system for occupational diseases were computed by Excel for windows and statistical significance by SAS 6.12. RESULTS: A total of 108 372 cases were reported from 1997 to 2003. Among them, the incidence of occupational poisoning, and non-occupational poisoning accounted for 25.39%, and 74.61% respectively. The fatality rate was 6.86%. The average age was 36.83 years for all pesticides poisoning patients, and 15-59 years old patients accounted for 84.11%. Among 0-14 years old non-occupational poisoning patients, 0-4 years children accounted for 33.51%. Male patients were in the majority in occupational pesticides poisoning, female in non-occupational. Insecticides especially organophosphorus insecticides such as methamidophos, parathion, and omethoate comprised a higher proportion, accounting for 86.02% of the pesticides poisoning. CONCLUSION: More attention should be paid to pesticides poisoning by the government and medical workers engaged in public health.

Adolescent↗

Contributions of children's activities to pesticide hand loadings following residential pesticide application.

The role of children's activities in leading to pesticide exposure was evaluated by comparing pesticide loadings on the hands of children with the activities of the same children observed over a 4-h period. In all, 10 children ranging in age from 24 to 55 months were videotaped on the second day following a routine professional crack and crevice chlorpyrifos application in their homes. Before and following the video session, the children's hands were rinsed in isopropyl alcohol. Thus, only the chlorpyrifos that accumulated on and remained on the child's hands during the videotaping were removed for analysis after the videotaping session. The rinsate was analyzed for chlorpyrifos. The children's behaviors were quantified using virtual tracking device and the frequency and duration of behaviors, the hourly rate of behaviors, and the locations in which behaviors occurred were compared to hand loadings of pesticides. Pesticide hand loadings obtained following the videotaping sessions were associated with pesticide levels on surfaces and toys, but not with air levels. Pesticide loadings obtained following the videotaping sessions were also associated with frequencies, durations, and hourly rates of contact with bottles, and object-to-mouth behaviors, as well as contact duration with upholstered/textured surfaces. The hand loadings were also associated with the number of locations where the children exhibited object-to-mouth behavior and with children's use of house space during the videotaping sessions.

Activities of Daily Living↗

New challenges: residential pesticide exposure assessment in the California Department of Pesticide Regulation, USA.

Residential exposure assessment is in an early stage of development within many of the regulatory agencies responsible for pesticides. Some of the impetus for residential assessment comes from the Food Quality Protection Act (FQPA), a federal law adopted in 1996 in the USA. The FQPA mandates that the aggregate and cumulative risks from all nonoccupational sources of exposure to similarly acting pesticides be assessed. The development of methods for residential exposure assessment is therefore proceeding in tandem with methods for aggregate risk assessment. The California Department of Pesticide Regulation (Cal DPR) regulates pesticides in the state of California much as the US EPA does at the national level. While Cal DPR is not explicitly bound by the federal law, it recognizes the importance of residential exposure and of cumulative risk, and tries to harmonize its methods with those of US EPA. Accordingly, Cal DPR is developing guidance for residential exposure assessment. Some factors to consider are the following: (1) although the end goal may be total exposure from all sources, in order to regulate the use of products it is necessary to have separate estimates of exposure from individual sources and routes; (2) probabilistic approaches will be used increasingly, and they must separate variability and uncertainty; (3) there is a critical need for data on residential use of pesticides, including the frequency of mishaps and improper handling; (4) data are needed on long-term activity patterns of individuals, including residential and occupational history; (5) regulatory agencies need a way to identify and screen potential exposure scenarios, in order to streamline the risk assessment process.

California↗

Contribution of non-agricultural pesticides to pesticide load in surface water.

Two small creeks, tributaries of the River Ruhr near Schwerte, Federal Republic of Germany, were investigated to reveal the regional agricultural and non-agricultural sources of pesticide inputs and the main pathways to surface water. In addition, the receiving water was monitored for pesticides. The watersheds are situated at the northern margin of the Rhenian Schiefergebirge, a highland landscape in North-Rhine-Westphalia. Solid carboniferous shale is covered by a shallow layer of quaternary unconsolidated rock (porous aquifer thickness <5 m). Occurrence of herbicides such as chlortoluron, isoproturon and terbuthylazine in surface water could be due to their broad agricultural application in regional dominant crops, such as barley, wheat and maize. Occurrence of diuron and glyphosate results from their use in residential settlements and industrial areas as well as from weed control on railway tracks. Atrazine concentrations up to 0.8 microg litre(-1) indicated recent use of this herbicide, which has been banned since 1991, and was also the result of non-agricultural applications. Pathways for pesticide input to the receiving waters were related to both surface run-off and underground passage. Two-thirds of the observed diuron load in the surface water resulted from an input by run-off. This was expected as a result of total herbicide application targets to sealed surfaces infringing current regulations and recommendations. Diuron load varied between 0.6 and 1.2% of the estimated amount applied annually in the investigated catchments. Non-agricultural pesticide use contributed more than two-thirds of the whole observed pesticide load in the tributaries and at least one-third in the River Ruhr.

Environmental Monitoring↗