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Review of computerized orthoptics with specific regard to convergence insufficiency.

Traditional vision training or orthoptics has used line or contour targets to eliminate suppression and improve vergence performance. Manipulation of these stimuli is slow and arduous. Line stimuli require an experienced doctor/technician to interpret responses. Recently, automated vision training using microprocessor anaglyph stimuli, i.e., random dot stereograms (RDS), has been used in an operant conditioning paradigm. This technique has improved motivation of the patient, improved reliability, and provided standardization of therapy. In addition, the utilization of RDS associated with operant conditioning has been shown to improve vergence performance and to reduce asthenopia in the convergence insufficiency patient.

Accommodation, Ocular↗

The effect of orthoptic treatment upon the vergence adaptation mechanism.

This paper is a review of the research work that has been carried out over the past few years investigating the ability of the oculomotor system to adapt to prism-induced heterophoria. Our results show that subjects with normal binocular vision can adapt to horizontal and vertical prism-induced heterophorias whether fixating at distance or near. Further studies have shown that subjects with symptomatic abnormal binocular vision have an abnormal adaptation mechanism. Finally, we have found that when orthoptic treatment results in relief from the symptoms, there is an associated improvement in the subjects' ability to adapt to prism-induced heterophoria.

Adaptation, Ocular↗

[Orthoptic treatment efficiency in convergence insufficiency treatment].

We studied a group of 162 patients(89 females, 73 males), with ages between 15-30 years, who complained of blurred vision at near work. 98 patients(60.4%) were diagnosed with convergence insufficiency (C.I.), the rest of 64 patients(39.6%) had: low refractive errors, heterophoria and intermittent heterotropia. Patients with convergence insufficiency were divided in 3 groups: group 1(34 patients--34.6%) were treated with orthoptic exercises and near point exercises at home, group 2 (34 patients--34.6%) were treated with only near point exercises at home and control group 3 (30 patients--30.8%) without treatment. The result of the treatment of C.I. was good at 25 patients(73.5%) of group 1, at 8 patients(23.5%) of group 2 while in group 3 at only one patient the symptoms disappeared.

Adolescent↗

[Orthoptic treatment of accommodative strabismus].

Orthoptic treatment of accommodative strabismus is difficult because of variability of deviation and neutralisation. In first, the treatment of synoptophoria is practised more easily. It is often completed by optic treatment and medical treatment.

Accommodation, Ocular↗

Orthoptic treatment of vertical deviations.

Four patients with large vertical deviations were treated with a combination of prismatic glasses and orthoptics. The least amount of prism which eliminated diplopia, followed by horizontal fusional range extension, was prescribed. After vergences were normalized the prism was further reduced by two prism diopters and horizontal fusional range extension was repeated. This process was repeated until either a plateau was achieved or the prism was eliminated. All four patients completed therapy with almost total alleviation of symptoms and elimination of full-time prismatic correction.

Adult↗

Characteristics of exodeviations: II. Changes with treatment with orthoptics.

This study examined retrospectively the records of 179 patients who had binocular visual dysfunction as a result of an exodeviation (either at distance or near or both). The patients were classified as having convergence insufficiency (N = 110), equal exodeviations (N = 49), or divergence excess (N = 18). The diagnostic groups and the different frequencies of deviation reacted differently to treatment with a standard orthoptic regimen. Nearly all the patients (97%) achieved some improvement in either objective or subjective areas or both. However, fewer were able to satisfy the criteria set for total success. Factors correlated with the success of the treatment were the initial angle of deviation at distance and the initial level of stereopsis. The results and implications of this study are discussed.

Adolescent↗

The use of orthoptics in dyslexia.

In 73 children with reading difficulty, ophthalmological evaluation showed that 18 had overt refractive errors, 18 had dyslexia and no ocular anomalies, and 37 had impaired fusional amplitudes, 24 of whom were dyslexic. In all patients with poor fusional amplitudes the reading mechanism could be improved with orthoptic exercises designed to augment the fusional amplitudes. The treatment did not affect the perceptual defect associated with dyslexia.

Adolescent↗

Divergence excess: characteristics and results of treatment with orthoptics.

This paper retrospectively examines the results of the treatment of 18 subjects (11 males, seven females) with divergence excess, using orthoptics. The mean age of the subjects was 15.8 years, which was significantly younger than the population from which this group was referred. Diplopia (89%) and asthenopia (56%) were the most frequently reported symptoms. Seventy-two per cent of the subjects had intermittent deviations of the eyes. Over the mean necessary course of treatment of 5.2 weeks, the distance angle of deviation (slightly) and the positive vergences at distance and near were found to have changed significantly. The near angle of deviation, the negative vergences, the near point of convergence, the amplitude of accommodation, and the threshold of stereopsis were found to have remained stable over the treatment period. Further results of the study are presented and the implications of these results with regard to the treatment of divergence excess are briefly discussed.

Adolescent↗

Different rates of functional recovery of eye movements during orthoptics treatment in an adult amblyope.

Although it is common clinical knowledge that oculomotor control appears to normalize during the course of successful orthoptics therapy for amblyopia, reports providing a quantitative analysis of eye movements during extended periods of treatment are lacking. We provide for the first time such a report in an adult amblyope. Aspects of eye movement control that tended to normalize with therapy include drift amplitude and velocity, duration and frequency of steady fixation, and pursuit gain. These results suggest that smooth pursuit control can be modified, even in an adult amblyope. Aspects of eye movement control that remained abnormal throughout therapy, in spite of normalization of visual acuity and centralization of fixation, include increased saccadic latencies, use of large saccades during small-amplitude pursuit tracking, and static overshooting. These results suggest that certain aspects of saccadic and pursuit control could either no longer be modified or would require longer periods for this to occur.

Adolescent↗

Orthoptic status and reading disability.

147 unselected 8-year-olds were given tests of intelligence, reading ability and orthoptic status, including the reference eye test described by Dunlop, Dunlop and Fenelon (1973). We failed to replicate their findings of a raised incidence of convergence deficiency, defective stereopsis and esophoria in children with specific reading disability. Furthermore, in contrast to their results, we found that crossed reference (i.e. reference eye on opposite side to preferred hand) was common in this sample and not associated with reading problems.

Brain Mapping↗

[A few remarks on an oculistic and orthoptic screening of 61 monozygotic twin pairs (author's transl)].

An oculistic and orthoptic screening has been carried out on a sample of 122 twins aged 6 to 10 years (31 MZ male and 30 MZ female pairs). A few remarks could be made, concerning both twins as such and the heritability of the traits under examination. The twins appear to differ from the general population of singletons of the same age on account of a lower frequency of ametropia and strabismus as well as of a high frequency of epicanthus.

Child↗

[Critical (foveal) flicker fusion frequency (CFF) is helpful in differential diagnosis of organic lesions from orthoptic amblyopias].

PURPOSE: To measure critical (foveal) flicker fusion frequencies (CFF) in normal eyes, unilateral maculopathies and neuropathies and in orthoptic amblyopias. METHODS: A newly developed apparatus (4F) with LED's measured subjective foveal CFF by ascending and descending mode in a group of normals and patients. RESULTS: The apparatus (4F) measures temporal resolution. Foveal CFF ist more reduced in neuropathies than in maculopathies. In contrast, CFF in amblyopic eyes is hardly reduced, in most cases equal or better than in the dominant fellow eye. This is independent from the visual acuity of the amblyopic eye. CONCLUSION: CFF testing is useful in the evaluation of unexplained (unilateral) reduction of visual acuity. A dissociation between visual acuity and CFF (within normal range) is present in cases of amblyopia.

Amblyopia↗

[Results of conventional retinal detachment surgery. III. Orthoptic results].

In a comparative study we examined orthoptic side effects in 117 patients following conventional retinal detachment surgery. Of these, 54 had had a segmental scleral buckle, 18 a simple encircling band and 45 encircling band combined with a radial buckle. Persistent diplopia was found in 6% of cases following segmental buckles, in 11% following simple encircling procedures and in 20% following combined operations with encircling bands and segmental buckles. The incidence of diplopia was more than 30% in cases with high encircling buckles.

Adolescent↗

[Orthoptic treatment of dyslexia].

It is assumed that dyslexia is due to a brain-organic syndrome, either congenital or acquired in infancy, with specific gnostic deficiencies and faulty controlled binocular vision. The latter is expressed by an intermittent alternating central scotoma which is thought to be responsible for impaired visual perception during reading. The aim of the orthoptic treatment of dyslexia must therefore be to eliminate the alternating central scotoma by stabilizing the binocular vision, and thus to improve reading ability by achieving unimpaired visual perception.

Child↗

Effect of orthoptic procedures on stereoscopic acuities.

Ten stereophotogrammetry students and three graduate photogrammetrists were given 7 weeks of nonspecific orthoptic exercises. The visual systems of these 13 experimental subjects were matched to those of 13 control subjects chosen from the students and staff of the Ferris State College of Optometry. Stereoscopic acuities were determined before and after the training period on both groups using a Wild Stereoplotter, a Howard-Dolman apparatus, and the Keystone Multi-Stereo Test. Stereoscopic acuities as determined on the stereoplotter and the Howard-Dolman apparatus were improved at better than a 0.05 significance level as computed on the Wilcoxon signed rank test and Student's t-test for the difference between two dependent means.

Adult↗

Interaction between nelfinavir and tacrolimus after orthoptic liver transplantation in a patient coinfected with HIV and hepatitis C virus (HCV).

A 49-year old male patient with severe hemophilia A, coinfected with HIV and HCV, who underwent orthoptic liver transplantation because of hepatitis C cirrhosis is presented. We describe a strong interaction between nelfinavir and tacrolimus postoperatively, that caused a reduction of the dose of tacrolimus by a factor 70 compared with normal, to achieve therapeutic blood concentrations and to avoid toxic side effects. We suggest that nelfinavir inhibits the metabolism of tacrolimus because both compounds are well-known substrates for the cytochrome P450 isoenzyme CYP 3A4. The nelfinavir serum concentrations were not affected by the institution of tacrolimus. Although the interaction dramatically changed the tacrolimus dose-concentration relationship, the situation was manageable by frequent monitoring of blood concentrations of tacrolimus.

Drug Interactions↗

Orthoptic status before and immediately after heroin detoxification.

AIM: To determine whether changes in orthoptic status take place during withdrawal from heroin and/or methadone. METHOD: A prospective study of patients, using a repeated measures design, attending a 5 day naltrexone compressed opiate detoxification programme. RESULTS: 83 patients were seen before detoxification (mean age 27.1 (SD 4.6) years) and 69 after detoxification. The horizontal angle of deviation became less exo/more eso at distance (p<0.001) but no significant change was found at near (p = 0.069). Stereoacuity, visual acuity, and convergence were found to be reduced in the immediate post-detoxification period. Prism fusion range, refractive error, subjective accommodation, and objective accommodation at 33 cm did not reduce but a small decrease was found in objective accommodation at 20 cm. CONCLUSIONS: The eso trend found in these patients may be responsible for the development of acute concomitant esotropia in some patients undergoing heroin detoxification. However, the mechanism for this trend does not appear to be caused by divergence insufficiency or sixth nerve palsy.

Accommodation, Ocular↗