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Convention on nomenclature for DNA cytometry. Committee on Nomenclature, Society for Analytical Cytology.

Analysis of cellular DNA content by cytometry is important in clinical and biological research. Measurements are used widely to assess the relative DNA content of tumor stemlines and to assist in the detection and evaluation of malignant diseases. A review of the literature on DNA measurements in solid tumor and leukemias reveals a confusing variety of terms applied for the description of similar results. In order to facilitate the understanding of data and to standardize the terminology for DNA analyses, a questionnaire was distributed to more than 500 investigators. Subsequently, a workshop on terminology was held at the Combined Conference on Analytical Cytology and Cytometry IX and VIth International Symposium on Flow Cytometry, Schloss Elmau, West Germany, 18-23 October, 1982. The workshop nominated a nine-member committee to develop guidelines for nomenclature to be used in reporting results from analyses by DNA cytometry. The committee was charged by the Council of the Society for Analytical Cytology to complete this task and to publish its recommendations in Cytometry and in Cancer Genetics and Cytogenetics. The following guidelines are based on the questionnaires returned and the discussion at the workshop; they represent the unanimous recommendations of the committee. The five guidelines given herein apply to measurements of relative DNA content of cells that have been stained appropriately and analyzed by cytometry.

Animals↗

Vaccine nomenclature: the three-letter code. OMCL Vaccine Nomenclature Drafting Group.

With increasing worldwide use of combined vaccines a short and informative system of names or codes for vaccines is essential. In addition, within the EU eleven official languages exist and some more are used. Due to these facts an increasing risk of medication errors for vaccines is emerging. A three-letter code naming system was first developed as part of the Note for guidance on pharmaceutical and biological aspects of combined vaccines (CPMP/BWP/477/97), but was deleted there later. Then a second approach was initiated by the European OMCL Network in order to implement this three-letter code system in the common nomenclature guideline within the Ph. Eur. (Index of standard terms). Both activities have not been successful until now to implement this system. Therefore we now present the three-letter code system in order to initiate either its voluntary use by vaccine manufacturers or to accelerate the obligatory implementation within the EU legislative framework. This coding system is thought to be used in addition to the brand name of the vaccine on the label of the final vaccine container, in order to have a safe last minute check whether the appropriate antigens are given.

Terminology as Topic↗

Proposed standard nomenclature for new tumor necrosis factor members involved in the regulation of bone resorption. The American Society for Bone and Mineral Research President's Committee on Nomenclature.

Recently, three new family members of the tumor necrosis factor (TNF) ligand and receptor signaling system that play a critical role in the regulation of bone resorption have been identified and cloned. These also have been shown to play an important role in regulating the immune system. A proliferation of synonyms for these molecules has led to miscommunication and redundancy. To resolve this, the President of the American Society for Bone and Mineral Research (ASBMR) appointed a special committee to recommend a standard nomenclature. After considerable deliberation and after vetting by workers in the field, the Committee recommends the names of receptor activator of NF-kappaB (RANKL) for the membrane receptor, RANK ligand (RANK) for the ligand, and osteoprotegerin (OPG) for the decoy receptor.

Bone Resorption↗

Nomenclature for factors of the dog major histocompatibility system (DLA), 2000: second report of the ISAG DLA Nomenclature Committee.

The International Society for Animal Genetics (ISAG) Dog Leukocyte Antigen (DLA) Nomenclature Committee met during the "Comparative Evolution of the Mammalian major Histocompatibility Complex (MHC)" meeting in Manchester, UK on 10 September 2000. The main points discussed were the naming of class I genes and alleles, and the inclusion of alleles from other canidae.

Alleles↗