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AIDS-related risk factors, medical diagnosis, do-not-resuscitate orders and aggressiveness of nursing care.

Three variables were experimentally manipulated through simulation in six case study vignettes: AIDS-related risk factors (gay v. IVDU), medical diagnosis (AIDS v. non-AIDS), and DNR orders (DNR order v. no DNR order). Following each vignette, the same 13-item, 6-point Likert-type Aggressiveness of Nursing Care Scale (ANCS) was used to measure nurses' attitudes toward aggressiveness of nursing care. Questionnaires were randomly assigned to 600 acute care nurses. Although AIDS-related risk factors were not found to influence ANCS scores, a non-AIDS medical diagnosis and DNR orders significantly reduced aggressiveness of nursing care attitudes. Study findings did not vary according to nurses' age, academic preparation, or previous practice experience with persons with AIDS or DNR orders.

Acquired Immunodeficiency Syndrome↗

Serologic survey for Borrelia burgdorferi antibody in horses referred to a mid-Atlantic veterinary teaching hospital.

Blood samples obtained from 13 of 100 (13%) and 6 of 91 (7%) horses at the George D. Widener Hospital for Large Animals in the months of June and October, respectively, had antibody to Borrelia burgdorferi as determined by ELISA. Horses from the states of New York, Maryland, Delaware, New Jersey, and Pennsylvania were seropositive for B burgdorferi. The frequency of antibody response in horses from New Jersey was greater (P less than 0.05) than the frequency of antibody response in horses from Pennsylvania or that of horses from the other states combined. Statistically significant difference was not found when a comparison was made between horses with serotiter and open diagnosis of neurologic or musculoskeletal disease and horses with negative serotest results and open diagnosis of neurologic or musculoskeletal disease.

Animals↗

The Mid-Atlantic Oncology Program's comparison of two data collection methods.

The Mid-Atlantic Oncology Program (MAOP) compared clinical trial data collected by circuit riding data managers (CDMs) from the MAOP statistical center with data collected by local data managers (LDMs) from clinics and practices, the latter being the standard data capture method in cancer clinical trials. LDMs and CDMs filled out identical study forms, using the same patient charts, for randomly selected patients on MAOP protocols. All coded answers on the forms were compared by one of the authors (DJ) and discrepant items were resolved in a blinded manner by the local MAOP physician acting as the principal investigator (PI). Thirty-three patient charts were reviewed with 53 pairs of forms completed and 1023 pairs of codes compared. A total of 129 (13%) pairs of codes were considered discrepant. Of the 100 discrepancies resolved (29 items were answered differently by the CDM, LDM, and PI) the PI's answers matched 66 of 100 codes as recorded by the CDMs and 34 of 100 codes as recorded by the LDMs. This results in chi 2 = 9.61 (p less than 0.005), demonstrating a significant difference between the frequency with which the PI's answers matched data collected by the CDMs and LDMs. It was also determined that CDMs consistently coded toxicities as more severe than did LDMs and were more often correct. Given the results of this study, CDMs should be considered an acceptable alternative to LDMs in the context of regional programs.

Bias↗