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Paracelsus confronts the saints: miracles, healing and the secularization of magic.

The sixteenth and seventeenth centuries witnessed an erosion of the role played by the church in healing. Magical practices mediated by the church were replaced by the resources of medicine. This represented an important cultural development and it is often regarded as a manifestation of increasing secularization, the decline of magic and rise of science. This paper examines this issue with special reference to miraculous healing associated with saints, which constituted one of the most important facets of magic controlled by the church. It will be suggested that Paracelsus (Theophrast von Hohenheim, 1493-1541) played an important part in the argument concerning the miraculous powers of saints. Many works by Paracelsus produced at various points in his career were relevant to this issue, but De causis morborum invisibilium, the sequel to his important Opus Paraminum (1531), was especially significant. The question of miraculous healing was therefore important in the first, full presentation of the new system of medicine developed by Paracelsus. Modern commentators have understandably found De causis morborum invisibilium less intelligible and congenial than the more accessible Opus Paramirum. But the former was important to Paracelsus, and it addressed problems that were fundamental to his audience. This case-study shows how conclusions reached by Paracelsus about medical questions were integrally tied up with his theological standpoint and with his wider reaction to the acute crisis of confidence which affected the church and the established social order at the beginning of the sixteenth century. By eliminating the miraculous intervention of saints and promoting the secularization of magic, Paracelsus was contributing to one of the important cultural changes associated with the Reformation.

Christianity↗

Reasonable magic and the nature of alchemy: Jewish reflections on human embryonic stem cell research.

The controversy about research on human embryonic stem cells both divides and defines us, raising fundamental ethical and religious questions about the nature of the self and the limits of science. This article uses Jewish sources to articulate fundamental concerns about the forbiddenness of knowledge in general and of knowledge thought of as magical creation. Alchemy, and the turning of elements into gold and into substances for longevity, and magic used for the creation of living beings was at stake in various Talmudic texts. Since contemporary discourse calls regenerative science magical, and makes claims about its restorative power, careful reflection on when magic is forbidden and when it is responsible allows a novel understanding of ethical questions in stem cell research.

Alchemy↗

Magical ideation and right-sided hemispatial inattention on a spatial working memory task: influences of sex and handedness.

A correlation between magical ideation scores and the size of relative right-sided hemispatial inattention was previously reported for healthy right-handed men performing a tactile line-bisection task. To re-investigate this relation, a computerized version of Corsi's Block-Tapping Test was used to test working memory. In this version, different numbers of cubes are similtaneously displayed on a screen, and after the cubes disappear the subject is asked to designate the cubes' locations on a grid as quickly as possible. 98 healtly medical students were divided into four groups on the basis of their handedness and sex in the following way: right-handed men, right-handed women, nonright-handed men, and nonright-handed women. Each subject performed the test once with the right hand and once with the left hand. Accuracy and Neglect scores were computed for the two hemispaces separately. Also, all subjects filled in the Magical Ideation Scale which asks for hallucination-like experiences and delusion-like beliefs. In all groups a significant right-sided inattention was found when subjects performed with the right hand. Magical Ideation scores were significantly correlated with Neglect in the right hemispace for the right-handed women when the right hand was used. For the nonright-handed men, when the right hand was used, a significant negative correlation between Magical Ideation scores and Neglect scores in the left hemispace was found. Our findings support the previous study in some aspects and suggest that the correlation between hemispatial inattention and proneness to schizotypy in normal subjects is restricted to right-hand performance.

Adult↗

Magic angle imaging of the achilles tendon in patients with chronic tendonopathy.

AIMS: To assess the Achilles tendon in patients with chronic tendonopathy using magnetic resonance (MR) magic angle imaging, and to compare the appearances and uptake of contrast medium in abnormal tendons with those in normal tendons. MATERIAL AND METHODS: Eight patients with chronic Achilles tendonopathy and five normal controls were examined with the long axis of the tendon placed at 55 degrees and at 0 degrees to the main magnetic field. Conventional two-dimensional (2D) multi-slice images were obtained and T1 values were calculated before, and for up to 1h after the administration of intravenous gadodiamide. Both the unenhanced appearance and the pattern of enhancement in the tendon were compared. RESULTS: In the patients with tendonopathy, high signal intensity areas were evident on the short T1 inversion recovery (STIR) images obtained at 55 degrees in all tendons. Contrast medium enhancement was seen in six tendons and was most obvious on the images obtained at the magic angle. This was initially focal and then spread more diffusely within the tendon. After contrast medium administration, T1 values were significantly reduced in the tendonopathy group compared with normal controls (p<0.01). On the late post-contrast medium images obtained at 55 degrees, enhancement was evident in most of the tendon and correlated well with high signal intensity seen on STIR images. CONCLUSION: The use of magic angle MR imaging improved the demonstration of signal changes in the Achilles tendon in chronic tendonopathy. The STIR images obtained at the magic angle showed more obvious signal change than those obtained at 0 degrees. The changes due to enhancement were much more evident on images obtained at 55 degrees than at 0 degrees. The uptake of contrast medium was greater in the patients than in normal controls.

Achilles Tendon↗

Application of amplitude-modulated radiofrequency fields to the magic-angle spinning NMR of spin-7/2 nuclei.

We report pulse sequences for the sensitivity enhancement of magic-angle spinning and multiple-quantum magic-angle spinning spectra of spin-72 systems. Sensitivity enhancement is obtained with the use of fast amplitude-modulated (FAM) radiofrequency pulses. In one-dimensional magic-angle spinning experiments, signal enhancement of 3 is obtained by a FAM pulse followed by a soft 90 degrees pulse. In two-dimensional multiple-quantum magic-angle spinning experiments, FAM pulses are used for both the excitation of multiple-quantum coherences and for their conversion into observable single-quantum coherences. The observed signal enhancements are 2.2 in 3Q experiments, 3.1 in 5Q experiments, and 4.1 in 7Q experiments, compared to the conventional two-pulse scheme. The pulse schemes are demonstrated on the 45Sc NMR of Sc2(SO4)3 x 5H2O and the 139La NMR of LaAlO3. We also demonstrate the generation of FAM pulses by double-frequency irradiation.

Journal Article↗

High-resolution NMR spectroscopy of quadrupolar nuclei in solids: satellite-transition MAS with self-compensation for magic-angle misset.

Several methods are available for obtaining high-resolution NMR spectra of half-integer spin quadrupolar nuclei, such as (11)B, (23)Na (I = (3)/(2)) and (17)O, (27)Al (I = (5)/(2)), in powdered solids. Satellite-transition magic-angle spinning (STMAS) uses only conventional magic-angle spinning (MAS) hardware and, it has been claimed, improves significantly upon the signal-to-noise ratio obtained with the widely adopted multiple-quantum MAS (MQMAS) experiment. The STMAS technique, however, requires that the sample rotation axis be set to the magic angle (cos(-1)(1/ radical 3) = 54.736 degrees ) with respect to the magnetic field B(0) with an accuracy of better than +/-0.004 degrees, and this stringent requirement has severely limited the use of the method. Here, we propose a novel version of STMAS that self-compensates for magic-angle missets of up to +/-1.0 degrees and yet retains a sensitivity comparable with MQMAS. This SCAM-STMAS experiment is demonstrated on RbNO(3) using (87)Rb (I = (3)/(2)) NMR and on kyanite (Al(2)SiO(5)) using (27)Al (I = (5)/(2)) NMR.

Journal Article↗

Magical beliefs and rituals in young children.

Thirty-one children were administered a structured interview that assessed their beliefs about magic, tricks and wishes. Children were also presented with demonstrations of magic tricks/illusions, and asked to offer explanations as to how they worked. Parents completed the Childhood Routines Inventory (CRI), a 19-item parent report measure that assesses children's rituals, habits and sensory-perceptual experiences that we have termed "compulsive-like" behavior. Results indicated that children's rituals and compulsions were positively related to their magical beliefs, and inversely related to their uses of concrete, physical explanations to describe various phenomena. In particular, children's beliefs about the effects of wishing were most consistently correlated with their compulsive-like rituals and routines. The findings extended the work on magical beliefs and obsessive-compulsive phenomena to the normative manifestation of compulsive behaviors found in typical development.

Child↗

Magic-angle effect in magnetic resonance imaging of articular cartilage: a review.

RATIONALE AND OBJECTIVES: The laminar appearance of articular cartilage in magnetic resonance (MR) images has been a source of confusion, especially concerning the number, intensity, thickness, and origin of the layers. The laminar appearance is associated with the magic-angle effect in the MR imaging (MRI) of articular cartilage. METHODS: This article introduces the topic with background information about cartilage and the magic-angle effect and then reviews the literature about the magic-angle effect. The review concludes with a brief discussion of the future directions of study and the potential clinical relevance of the laminae in MR images of articular cartilage. CONCLUSIONS: The magic-angle effect is commonly seen in MR images of several tissues. The direct cause of the laminar appearance of articular cartilage is the T2 relaxation anisotropy in the tissue, which is closely linked to the structure of the collagen fibers, their orientation in the magnetic field, and the water-proteoglycan interaction that amplifies the prevailing orientation of the collagen fiber network. The laminar appearance of cartilage has an intrinsic spatial heterogeneity over the two-dimensional joint surface, which leads to inconsistencies in the reported total number of cartilage laminae and the laminar patterns observable in MRI, depending on where the sample was taken. Two additional thin, low-intensity laminae may also be visible at the boundaries of the cartilage with fluid and with bone; whether these boundary laminae are identified and counted with the others may introduce inconsistency in the results reported by various researchers.

Cartilage, Articular↗

Comparison between MAGIC LITE- and CAP-system: two automated specific IgE antibody assays.

The MAGIC LITE system, a newly developed immunochemiluminometric assay for specific and total IgE antibody using paramagnetic particles coupled with standardized allergens as solid phase, was compared to the CAP system, a recently introduced immunoassay based on a cellulose polymer encased in a capsule. A total of 357 serum samples of patients with suspected inhalant allergies and a positive skin prick test (SPT) to common allergens (birch, timothy-grass, mugwort, cat dander, Dermatophagoides pteronyssinus, Alternaria) were investigated. Fifty SPT negative subjects served as controls (total number of tests in each assay = 1600). Both assays were highly precise (overall intra-assay and inter-assay coefficients of variation were 2.9% and 4.5% in MAGIC LITE, 4.7% and 5.5% in CAP) and showed excellent linearity (mean r2 of eightfold log2 serum dilutions were 99.7% and 99.3% in MAGIC LITE and CAP). Good correlations were found between the absolute specific IgE antibody values detected by both methods (correlation coefficient r: birth 0.86, grass 0.93, mugwort 0.96, cat 0.91, D. pteronyssinus 0.73, Alternaria 0.90). Excellent specificity (greater than or equal to 98%) occurred in both assays and with all allergens, and sensitivity was related to the allergen (MAGIC LITE/CAP): birch 91%/89%, grass 83%/90%, mugwort 50%/69%, cat 83%/83%, D. pteronyssinus 72%/78%, Alternaria 75%/81%. Our results indicate that both in vitro tests are useful tools for the detection of specific IgE antibody.

Allergens↗

Rotational diffusion effects on absorbance measurements: limitations to the magic-angle approach.

Optical absorbance changes are commonly used to characterize intermediates which appear in the bleaching sequence of rhodopsin and in the photocycle of bacteriorhodopsin. Absorbance changes can be caused by an intermediate's rotational diffusion, and when this occurs it can distort absorbance changes due to the structural evolution of intermediates. Linear polarization of an optical probe source at 54.7 degrees (the magic angle) relative to the polarization direction of a linearly polarized actinic source has often been used to eliminate signals due to rotational diffusion. We used Jones calculus to investigate the validity of the magic-angle strategy. Taylor expansion of the result in powers of the absorbances of the bleached ground state and of the intermediates leads to a relatively simple expression which can be used to determine whether rotational contributions are likely under various experimental conditions. This expression shows that in first order no dichroism-dependent term appears in the absorbance measured at magic angle. In second order, however, linear dichroism contributes to signals. For the sequence of rhodopsin intermediates: rhodopsin hv----bathorhodopsin in equilibrium BSI----lumirhodopsin, where BSI is a recently discovered blue-shifted intermediate, we determined the magnitude of the dichroism signals to be, on average, less than 2% of the true absorbance change due to the intermediates themselves (and hence undetectable). Freedom from dichroism artifacts in this case results from the fact that the transition dipoles of these intermediates are similar to that of rhodopsin. Larger and certainly detectable dichroism signals are predicted to occur, even at the magic angle, for later intermediates which have transition dipole moments which differ significantly from that of rhodopsin.(ABSTRACT TRUNCATED AT 250 WORDS)

Bacteriorhodopsins↗

Slow magic: psychoanalysis and "the disenchantment of the world".

Freud's work can be situated in terms of the debate between Enlightenment and anti-Enlightenment thought. The attempts of both sides to claim Freud for their position have merit, but they miss the crucial point: namely, that the tension between its Enlightenment and anti-Enlightenment tendencies is what gives Freud's thinking much of its vitality and depth. The task that faces the interpreter is therefore to elucidate that tension and assess the alignment of forces between the two strands in his thought. An examination of the concept of magic in Freud's theory provides an opportunity to pursue this interpretive task. Although the Enlightenment position he often seems to embrace advocates the complete elimination of magic, many "magical" elements remain in his theory and clinical practice. Nor should this situation be deplored, for the ambition to completely exorcise "enchantment" from human experience is one of the misguided excesses of the Enlightenment. The question of an appropriate fate for magic in psychoanalysis is discussed in relation to the vicissitudes of the transference. Finally, the science versus hermenueutics debate is examined in the light of these considerations in an attempt to specify the unique nature of the psychoanalytic experience.

Humans↗

[Evaluation of the Magic Lite SQ specific IgE kit].

The new IgE specific antibody assay kit (Magic Lite SQ) was evaluated by comparing its results with those obtained by the Phadebas RAST and the skin prick tests. Sera from allergic children were used in the tests. The correlation coefficients between the Magic Lite SQ and the Phadebas RAST were as follows: 0.87 for D.p., 0.89 for D.f., 0.87 for HD1, 0.55 for HD2, 0.76 for orchard grass, 0.93 for cat dander, 0.78 for Alternaria, 0.88 for egg white, 0.75 for egg york, 0.81 for milk, 0.75 for say bean, and 0.60 for shrimp. The concordance rate of the two methods was high, except on the case of HD2. The sensitivity and specificity of Magic Lite SQ to the skin prick test was high, except on the case of HD2 and orchard grass. Dilution tests using samples from D.f. positive patients showed a good linearity and excellent quantitativeness. When mite allergen was added to D.f. positive pool serum, mite specific IgE antibody yielded an excellent inhibition curve of up to a maximum of 96%. Since the Magic Lite SQ requires only a small sample of serum and can completed the test in a short time, it is a useful and specific IgE antibody assay kit.

Child↗

From Mantra to Mataráa: opacity and transparency in the language of Tobelo magic and medicine (Halmahera Island, Indonesia).

This paper presents a definition of the Tobelo concept of 'magic/medicine', and examines the role of mataráa ('magical formulae') within Tobelo magical/medical activities. The curative use of opaque, esoteric formulae is widely reported; Tobelo also have a specialized speech I call 'neo-Ternatese' used for this purpose. Several explanations for the opacity of magical formulae are examined; some apply to the Tobelo case and some do not. Examining the full range of registers in which neo-Ternatese is used, with sample texts, we find a continuum from transparent to opaque, paralleling a continuum of contexts from public to private (or esoteric), and we can identify the techniques used to produce (or increase) a text's opacity. Magical formulae, at the opaque end of that continuum, represent a secret, prestigious, and relatively liquid asset whose high value is maintained by several cultural conventions.

Humans↗

Headache in magical and medical papyri of ancient Egypt.

Despite the intensity with which many scholars have studied the evolution of Egyptian medicine, interdisciplinary studies on the history of headache are scarcely extant. Following a short discussion of historiographical issues, the main objective of this paper is to present a comprehensive and detailed overview on this subject. Scattered references to headache are extracted from so-called magical papyri and from medical texts of the New Kingdom. Although little is known about the quality of headache and about accompanying symptoms, four predominant localizations are distinguished. Due to the lack of precise descriptions it is impossible to establish the retrospective diagnosis of migraine. Explanations of the origin of cephalalgia and of the corresponding therapeutic actions differ according to the nature of the source. In magical papyri, headaches are attributed to the action of demons and supernatural forces, whereas medical papyri emphasize the role of head trauma and of 'pain matter' occurring in the body. Treatment could be magical, pharmacological or surgical. Examples of incantations and prescriptions are analysed in detail.

Egypt, Ancient↗

Freud, Piaget, or neither? Beliefs in controlling others by wishful thinking and magical behavior in young children.

Tests showed that 4- to 6-year-old children believe that people can be influenced or "controlled" both by thinking (e.g., both wishful thinking and magical behavior) and by realistic means (e.g., positive reinforcement, example, and group pressure). Belief in control by thinking did not vary by the subjects' sex or age, influence type (wishing or magical behavior), or target response (behavior, emotion, or thought). Quantitative measures, however, suggested that magical behavior was seen by subjects as being more efficient than wishing, and that emotion was considered easier to influence than thinking. Beliefs in control by thinking were not related to a measure of fantasy-reality differentiation (realism).

Child↗

The resurrection of a magical reality: treatment of functional migraine in a child.

A magical world view and logic were used in the treatment of a 10-year-old girl who was referred because of suicidal threats due to migrainous pain. The treatment consisted of a one-session intervention with three-week, six-month, and one-year follow-up indicating elimination of migraine. Within a strategic family therapy, a magical ritual was prescribed that derived from the preoperational logic explicated by Piaget and from the healing practices described in anthropological studies. Such a ritual casts the symptom in a different context, alters the meaning of migraine to the family system, and leads to different interactional patterns. Piaget's theory and anthropological data are discussed as sources of a magical world view to help families and children disengage from a symptomatic system of interactions.

Child↗

[Birth representation with reference to the magical coriander prescription of Codex Vindobonensis 93, fol. 102r, of the Austrian National Library].

One of the most impressive manuscript illustrations of the medieval history of midwifery is found in the Codex Vindobonensis 93, fol. 102r (a manuscript from the early 13th century), illustrating a magic prescription of herba coriandrum to accelerate childbirth. The composition of the omnibus manuscript is critically delineated in its historical context. The illustration, being isolated without any obstetrical teaching text, is judged as part of the ancient tradition of teaching by images which has no parallel north of the Alps. The different image traditions are reflected in the historical use and illustration of the midwifery chair, which can be traced back only to the beginning of the 16th century in Central Europe and on the British Isles. The importance of the magic prescription is shown by comparison within the same and other collections used in the Middle Ages and classified in the context of further traditions of magic in midwifery.

Europe↗

Magical ideation modulates spatial behavior.

Previous research has found that animals as well as persons with psychotic disorders preferentially orient away from the cerebral hemisphere with the more active dopamine system. This study investigated the modulation of spatial behavior by a mode of thinking reminiscent of the positive symptoms of psychosis. In a non-treatment-seeking sample of healthy volunteers (20 women and 16 men), the authors assessed the lateral biases in turning and veering behavior and in line bisection as a function of their magical ideation, that is, a mild form of schizotypy. Across tasks, pronounced magical ideation was associated with reduced right-sided orientation preferences. This finding suggests a relative hyperdopaminergia of the right hemisphere as the biological basis of magical ideation.

Adult↗