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New library buildings. Part VI: Sciences Library, Brown University.

Brown was one of the first universities in the nation to combine its science collections into a single library in the interest of aiding interdisciplinary teaching and research. This paper discusses the evolution of the Sciences Library and its resources, the development of the medical education program, and the physical aspects of the new library building. A fifteen-story tower, housing the collections of the physical, biological, and medical sciences, symbolizes the interdisciplinary approach to teaching and research at Brown University.

Architecture

Studies on locus expansion, library representation, and chromosome walking using an efficient method to screen cosmid libraries.

We have developed an efficient screening method to search for clones in cosmid libraries prepared from human genomic DNA. Genomic, cDNA, and cosmid probes have been used to isolate homologous cosmids from human chromosomes 7, 10, 16, 17 and X as part of a search for polymorphic nucleotide sequences. This method has been successfully applied to chromosome walking experiments at the interstitial retinol-binding protein locus on chromosome 10, and may be a useful tool for investigating representation of cloned sequences in cosmid libraries. Our library was prepared in the vector c2RB (Bates and Swift, 1983), but the method is applicable to any cosmid cloning system in which the inserted DNA can be separated from the vector by restriction enzyme digestion. A cosmid library containing five human genome equivalents can be rapidly screened using three to four Southern hybridization filters. This results in substantial labor saving, particularly when screening genomes of high complexity with many different probes. Another advantage of the system is that it allows for the long-term storage of the cosmids so that they can be screened whenever necessary. As a consequence, cosmid screening can be made a routine laboratory procedure.

Blotting, Southern

Indexing the sequence libraries: software providing a common indexing system for all the standard sequence libraries.

We describe a set of programs for creating and using indexes for the distributed forms of the major sequence libraries. The indexes conform to the specification of those distributed on cd-rom by the EMBL sequence library. The programs create entry name, accession number, author and freetext indexes and a brief directory index. If a suitable application program is given an entry name or accession number these indexes allow rapid retrieval of sequences or annotation. Similarly the author and freetext indexes provide the data for extremely fast searching on author names and "keywords". The indexing programs can create indexes for EMBL, Swiss-Prot, GenBANK, PIR and NRL3d libraries. We also describe the organisation and use of the different sequence libraries and their index files.

Abstracting and Indexing

Mechanization of library procedures in a medium-sized medical library: XVI. Computer-assisted cataloging, the first decade.

After ten years of experimentation in computer-assisted cataloging, the Washington University School of Medicine Library has decided to join the Ohio College Library Center network. The history of the library's work preceding this decision is reviewed. The data processing equipment and computers that have permitted librarians to explore different ways of presenting cataloging information are discussed. Certain cataloging processes are facilitated by computer manipulation and printouts, but the intellectual cataloging processes such as descriptive and subject cataloging are not. Networks and shared bibliographic data bases show promise of eliminating the intellectual cataloging for one book by more than one cataloger. It is in this area that future developments can be expected.

Cataloging

Planning a new library in an age of transition: the Washington University School of Medicine Library and Biomedical Communications Center.

In an era of great technological and socioeconomic changes, the Washington University School of Medicine conceptualized and built its first Library and Biomedical Communications Center in seventy-eight years. The planning process, evolution of the electronic library, and translation of functions into operating spaces are discussed. Since 1983, when the project was approved, a whole range of information technologies and services have emerged. The authors consider the kind of library that would operate in a setting where people can do their own searches, order data and materials through an electronic network, analyze and manage information, and use software to create their own publications.

Facility Design and Construction

Medical libraries and computers. The role of medical libraries in medical informatics.

The classic function of health sciences libraries is to build and maintain a knowledge base and to provide timely access to that collective memory for the purpose of learning, teaching, caring for patients, conducting research or managing an organization. The formats and representation of that knowledge base are changing rapidly, as are the methods and techniques for gaining access to information. Medical libraries have long used computers for cataloging and controlling records but are now shifting to acquiring, managing and distributing bibliographic and full-text information to local library "networks."

Computer Communication Networks

Library orientation methods: J. Hillis Miller Health Center Library program.

Two orientation devices are described which are currently in use at the J. Hillis Miller Health Center Library. One is a taped tour which requires a portable recorder with earphones attached. Tapes are now available for nursing students, physical therapy students, and Health Center staff. The tour includes location information and description of the card catalog and certain basic index and abstract services. The second orientation device is a short instruction tape on the use of Index Medicus which is attached to the Index Medicus table. This is heard through a telephone apparatus. It is anticipated that the tape technique will be expanded to apply to other students and other library tools. It is also believed that this technique may be used in other libraries. Information about the supplies and equipment used is given as an addendum.

Abstracting and Indexing

Health science libraries in the United States: III. Hospital health science libraries, 1969-1979.

Health sciences libraries in hospitals were examined from longitudinal data collected in 1969, 1973, and 1979, to derive parameters for the universe and for resources, services, and manpower. The surveys show that during this period, the number of hospitals decreased whereas the number of libraries increased. Growth in the number of community hospital libraries was counterbalanced by changes in federal, psychiatric, tuberculosis, and chronic illness hospitals.

Hospitals

Area health education center libraries and medical school libraries: establishing an interface.

Establishing an interface between area health education center (AHEC) libraries and medical school libraries requires careful planning, including: the overall plan, needs assessment, resource evaluation, a developmental plan, monitoring and evaluation, institutional agreements, and publicity. This paper reports on the development of AHEC libraries in North Dakota.

Health Education

Practical library research: a tool for effective library management.

Librarians are being urged to conduct research as one of their professional responsibilities. Many librarians, however, avoid research, because they believe it is beyond their capabilities or resources. This paper discusses the importance of conducting applied research-research directed toward solving practical problems. The paper describes how one library conducted practical research projects, including use studies and surveys, over an eighteen-year period. These projects produced objective data that were used by the library to make management decisions that benefited both the library and its parent institution. This paper encourages other librarians to conduct practical research projects and to share the results with their colleagues through publication in the professional literature.

Data Collection

New library buildings: the Houston Academy of Medicine--Texas Medical Center Library.

A historical account is given of the Houston Academy of Medicine--Texas Medical Center Library within its Texas Medical Center setting in Houston, Texas. Outlined are planning, financing, and construction of the new library, which consists in part of new building and in part of renovated interiors of an old building originally completed in 1954. A concise picture is given of the new library's interiors, showing its functional success for users and employees alike. An architectural summary is appended showing gross and net footages, source of funds, costs and capacities.

Facility Design and Construction

Selective medical libraries and library networks for developing countries.

The growth and rising cost of bibliographic materials require that attempts to make all medical libraries comprehensive and self-contained be replaced by the provision of selective collections devoted to the most used and useful materials, particularly in developing countries with limited resources. Journals constitute the most important and expensive component of a biomedical collection. While use data are important, a method is presented to guide selection in the absence of this information. The method identifies 35 nucleus journals and uses citation analysis to generate a list of 92 journals, partitioned into 31 medical specialty classes. Local expert consensus can guide selection of important local or regional literature not in the international archives. Careful selection results in efficient collections. Access to less used materials can be provided to individual libraries through resource sharing networks with affiliations to major comprehensive international libraries.

Developing Countries

Steps towards a computer-based library network: a survey of three medical libraries.

The introduction of a computerized biomedical network in three medical libraries in the State University of New York demanded a study of the various bibliographic records held by the libraries. The investigation produced figures relating to the total number of monographs held by each library and the number of unique titles owned by the network as a whole. These were broken down to identify the amount of works dating from 1962 or later, and estimates were made of the mean length of the normal bibliographic record, as well as of its traditional subareas. Thought was given to the implication of applying depth-indexing to monographs with reference to the length of the record.

Computers

Anchor-ligated cDNA libraries: a technique for generating a cDNA library for the immediate cloning of the 5' ends of mRNAs.

A new, efficient and simple method based on single-stranded anchor ligation has been developed that allows for the generation of an anchor-ligated library from which the 5' ends in many mRNAs can be cloned. Random hexamers are used to prime poly A+ RNA for the first strand synthesis of a cDNA library, and a modified single-stranded anchor is then ligated to the 3' end of the cDNA using T4 RNA ligase. The library can then be used to amplify the 5' end of any mRNA expressed in the tissue. The efficiency and utility of this method has been demonstrated by amplification of three human genes: transferrin receptor, tissue-type plasminogen activator and beta actin.

Actins

New library buildings. Part VII. The Health Sciences Library of the University of Virginia.

This article describes the new Health Sciences Library at the University of Virginia Medical Center in Charlottesville, Virginia. The library was under construction for about two years and opened in August 1975. It comprises an area of 66,250 sq. ft. gross, almost 44,000 sq. ft. net, and provides space for approximately 190,000 volumes, 500 readers, and a staff of 35. The cost of construction was $2,350,000, plus approximately $400,000 for furnishings and equipment. A portion of the library is located on a bridge spanning a four-lane highway. Special features include a 6,000 net sq. ft. audiovisual information center, Elecompack (TM) motorized shelves for little-used materials, and a closed-circuit television surveillance system.

Facility Design and Construction

New library buildings. Part VIII. The Library of the Health Sciences, University of Illinois at the Medical Center, Chicago.

The new Library of the Health Sciences at the University of Illinois at the Medical Center is described and illustrated. The building was under construction for thirteen months, using phased construction techniques, and opened in October 1973. The library is a self-contained and physically independent building consisting of three levels above ground and one lower level, comprising an area of 130,000 sq. ft. gross and 88,000 sq. ft. net. The building provides space for 350,000 volumes, 1,037 readers, and a staff of 100. The cost of construction was $5,140,500 plus $858,500 for furnishings and equipment. Among the special features are a twenty-four-hour multimedia services department and a full-circulating style book detection system. Included in the article is an evaluation of the library after two years of occupancy.

Chicago

The regional medical library and the hospital library.

A description of the origin of the Regional Medical Program is given and of regional service activities. Among the topics discussed are interlibrary loans, MEDLARS searches, orientation of librarians and library users, including workshops and the library Core collection, and the evaluation of needs for biomedical information in the regions.

Information Services