[Atrial heart septal defects in the aged].
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The association of congenital cataracts, microphthalmia and heart disease is well recognized in fetal rubella, but genetic causes are comparatively rare and recurrence risks are usually low. We describe a woman with an atrial septal defect, bilateral congenital cataracts, unilateral microphthalmia and minor dysmorphic features, originally attributed to an unidentified infection in utero, whose daughter has a similar constellation of heart, eye and facial abnormalities. This may represent a new dominantly inherited syndrome.
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A case of spontaneous closure of a membranous ventricular septal defect by adhesion of the septal leaflet of the tricuspid valve is reported. There was evidence to suggest that thrombi developed in a pouch formed by the adherent leaflet, giving rise to emboli producing remote and recent infarcts in the brain.
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