[Late diagnosis of a nasal foreign body].
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The author has noted that the frequency of epithelial lesions appearing during the course of trials with soft hydrophilic lenses containing 40% water diminished almost completely with soft hydrophilic lenses containing 70% water. He attributes these epithelial lesions to anoxia occurring with soft hydrophilic lenses with 40% water. He compares the permeability to oxygen of different types of lenses according to their thickness. He concludes that at present the materials utilised and the thickness of the lenses do not allow permanent wear.
The paper, after discussing the problems associated with the implantation of cold-polymerizing polymethyl methacrylates, describes the methods and results of determining the diffusion of residual monomers from implanted Kallokryl K bodies. Also described and discussed are histological studies of the implant supporting tissue and possible consequences of the decreasing, but constant diffusion of residual monomers, respectively.
An experimental study of the capsules formed around the net lavsan prostheses at periods of from 7 days to 5.5 years demonstrated that in the process of prolonged implantation morphology and metabolism of the capsule connective tissue underwent changes which could be associated with the release from the implants of low molecular products producing a damaging effect on the tissues surrounding the implant.
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Authors report on an embolization due to synthetic thread following inplantation of a vascular prosthesis, demonstrated by means of polarization optics in the spleen, corresponding to the dacron threads of the prosthesis. Complications of that type following vascular operations should be taken into account.
A case is presented of chronic systemic Dacron and Teflon embolism arising from a Beall Model 103 mitral valve prosthesis installed 11 years earlier. The emboli induced intense foreign body reaction resulting in numerous microgranulomas throughout the body. Multiple microinfarctions in the brain accounted for repeated episodes of transient ischemic attacks. Wearing of the prosthesis with consequent embolic complications seems to be the inevitable terminal fate of such early models of the Beall valve. Regular assessment of the functional status of such prostheses, particularly those in place for more than 5 years, is strongly recommended.
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Evidence for a causal connection between Schistosoma haematobium-infection and carcinoma of the urinary bladder is discussed. A group relationship of schistosomiasis cancer to cancers as+sociated with asbestosis, foreign body implants, and cicatrization is suggested on the basis of several criteria. Results of experimental foreign body tmuorigenesis in mice are presented and elaborated in relationship to schistosomiasis cancer. Carcinogenic development at the cellular level is discussed with emphasis on the essential role of tissue-environmental conditions, especially fibrotic changes and macrophage quiescence.
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