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Results for “Decompression, Explosive”

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PubMed1975

Influence of hypothalamic hyperphagia on tolerance of lung to explosive decompression.

A study was made of the effect of hypothalamic hyperphagia on the tolerance of lung to explosive decompression in male Long-Evans rats. The control and hypothalamic hyperphagic rats were explosively decompressed together from 1 atm to an ambient pressure of 30 min Hg in 0.04s. The hypothalamic-lesiones rats gained from 252 g average weight to 460 g, a 82% gain. The respective figures for the controls. were from 248 g to 336 g and 36%. It was also observed that a considerable amount of fat was accumulated between pleura and lungs in experimental animals. The average accumulation of fat between pleura and lungs in experimental rats was 3.23 g, while the value of the control group was only 0.42 g. The difference was statistically significant. Such an increase of fat accumulation in the thoracic cage could decrease the tidal volume. The severity of decompression-induced pulmonary hemorrages might thus be decreased. On the other hand, it also seems possible that the soft fat cushion between pleura and lungs might damp the bruising of the pulmonary tissue against the resistant thoracic wall to a certain extent, thus resulting in a decreased susceptibility to decompression-induced lung damage. Besides , the mortality in obese rats undergoing explosive decompression was also significantly lower than that of the controls

Adaptation, Physiological↗
PubMed1962

Rupture of bacteria by explosive decompression.

Foster, John W. (University of Georgia, Athens), Robert M. Cowan, and Ted A. Maag. Rupture of bacteria by explosive decompression. J. Bacteriol. 83:330-334. 1962.-A device is described for instantaneously rupturing bacteria and other cells in a closed system under controlled conditions by explosive decompression. With this device, 31 to 59% of Serratia marcescens, ranging up to 20 mg (dry wt) of cells per ml, were ruptured after nitrogen saturation at 1740 psi. Under similar conditions, 10 to 25% of Brucella abortus and Staphylococcus aureus were ruptured. Rupture of these organisms produced readily separable cell walls. Centrifugation in linear glycerol gradients was applied to further separate cell walls from debris. Mycoplasma gallinarum, Leptospira pomona, and Eimeria tenella (avian coccidia) oöcysts were also broken up by the decompression chamber. Pressure and duration of saturation of cells with gas affected rupture efficiency. Within the limits of this study, concentration of organisms and volume of suspensions did not have a definite effect.

Bacteria↗