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SRS (Sequence Retrieval System) is an information indexing and retrieval system designed for libraries with a flat file format such as the EMBL nucleotide sequence databank, the SwissProt protein sequence databank or the Prosite library of protein subsequence consensus patterns. SRS supports the data structure of these libraries by providing special indices for implementing lists of subentities (e.g. feature tables) or hierarchically structured data-fields (e.g. taxonomic classification). A language (ODD) has been designed for the convenient specification of library format and organization, representation of individual data-fields within the system (design of indices) and structuring other data needed during retrieval. This ensures flexibility required for coping with different library formats, which are subject to continuous change. Queries and inspection of retrieved entries can be performed from a user interface with pull-down menus and windows. SRS supports various input and output formats but is particularly well adapted to the GCG programs.
The usual electroencephalography (EEG) recording consumes great amounts of paper, considerable storage space for records and much time and energy for their search and retrieval. In addition, we can not perform digitized analyses of the records with the present method. To solve these problems, our laboratory developed a new computerized system for EEG, in which data are retained in optic disks, and which has been in service for routine examination since December, 1988. The functions of the system and EEG filing system, include the collection, retention, retrieval, transmission and analyses of data with the reproduction of the original EEG and editing function of summary reports to be filed in the medical records. The summary report consists of summary, characteristic wave patterns picked up and edited from EEG, and spectral array and topographical mapping by digitized analyses of EEG. The condition for the collection of EEG data was 200 Hz/8 bit, and the reproduced wave patterns were accepted by all clinicians. The merits of the system include; (i) saving of paper, space and time needed for EEG, (ii) enabling the comparison of the wave patterns in the form of summary reports and (iii) the capability of digitized analyses of EEG by retaining the EEG data in the data base. The problems remaining to be improved for the system are the longer time required for examination (5-10 min) and the higher running cost (yen 460/order). Regarding the latter problem, a revised method which dispenses with recording paper is under consideration. That is, in the case of screening examinations, summary reports for medical records alone would be delivered to clinicians. This idea has been accepted by some clinicians. To realize the revised system, we presently are planning to establish a method to display EEG on CRT.
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The X-ray absorption spectrometry (XAS) technique has been widely used to determine the local structure of materials that are poorly suited to study by ordinary diffraction methods, such as fine particles or amorphous matter. XAS is among the major applications at synchrotron radiation facilities and many existing beamlines perform the measurement of XAFS (X-ray absorption fine structure) spectra. XAFS spectra can also be measured with conventional X-ray sources. Measurement of XAFS spectra is relatively straightforward, but real difficulties arise in the analysis and interpretation of the data. Contrary to single-crystal diffraction techniques, the structure is not obtained directly from the measured XAFS data. Model structures must be assumed and the corresponding simulated XAFS spectra must be calculated, with determination of which models best fit the measured data. Model building is a most important part of XAFS analysis, but creation of three-dimensional structures from crystal-chemical considerations can be a very time-consuming task. Utilization of a database of crystal structures and of its built-in structure analysis and display tools can considerably reduce the time and effort required by this task. As XAS is often used to study metals, a database of alloys and intermetallic compounds, such as CRYSTMET, incorporating an array of powerful tools, is then very useful.
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OBJECTIVES: This paper evaluates the new race/ethnicity codes for Asian Americans, Hispanics, and Native Americans that have recently been added to the Medicare enrollment database. METHODS: The race/ethnicity code revisions made by the Health Care Financing Administration are described and evaluated by (1) comparing the numbers of persons identified as Asian Americans, Hispanics, and Native Americans with corresponding population census projections and (2) determining whether Medicare enrollees born in Asian and Hispanic countries are assigned Asian and Hispanic codes. RESULTS: Among persons 65 years of age and older, approximately 24% of Hispanics, 17% of Native Americans, and 56% of Asian Americans are identifiable by the new codes. From 18% to 29% of enrollees 65 years old or older born in Mexico, Puerto Rico, and Cuba are coded as Hispanic, and from 14% to 73% of enrollees born in nine Asian countries are classified as Asian American. Classification is not random but is related to timing of migration and to country of origin. CONCLUSIONS: Researchers should resist the temptation to base analyses on the revised Health Care Financing Administration race/ethnicity codes, since coverage is incomplete and biased.
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Over the period of 1995-1999 a total number of 439 cases were admitted to the Clinic of Acute Poisonings, Łódź, Poland, due to poisoning with opiates, opioids, amphetamine, cannabis products, LSD and cocaine. Most of the patients were males, the male to female ratio was 1:1.5 (266 to 173). The distribution by age indicated the persons aged 21-30 yr as the highest risk group, then those aged 14-21 yr. Over the period under study the structure of poisonings changed significantly. Since 1997 the number of poisonings with amphetamine and cannabis products increased dramatically, while that of opiate poisonings declined. Approximately 84% of cases were found to be addicted to a combination of drugs and psychotropic agents, mostly benzodiazepine and ethyl alcohol. Drug addiction was reported by over 80% patients with opiate poisoning, 44.8% with tetrahydrocannabinole poisoning and only 9.5% with amphetamine poisoning. The efficacy of treatment in cases of drug addiction is very low. Repeated treatment was reported by almost 100% of patients who had attempted to quit drug abuse. Among opiate poisoning cases, only 8 out of 45 patients did not question the effectiveness of the withdrawal treatment.
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