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PubMed2000

Power consumption in shaking flasks on rotary shaking machines: II. Nondimensional description of specific power consumption and flow regimes in unbaffled flasks at elevated liquid viscosity.

This article is the second part of a series presenting and modeling the hydrodynamics and specific power consumption in shaking flasks on rotary (orbital) shaking machines. In part I, a new method was introduced that enables the accurate determination of the specific power consumption in shaking flasks. The method was first applied to investigate unbaffled flasks with a nominal volume of < or =1 L at low viscosity. In part II, the results for the specific power consumption of unbaffled shaking flasks at elevated viscosities are investigated after varying shaking frequency, flask size, filling volume, and shaking diameter. The theory introduced in part I is extended to liquids of elevated viscosities using nondimensional equations. With these results, the specific power consumption in unbaffled shaking flasks can now be fully described. For the first time, the phenomenon of the liquid being "out of phase" is observed and described. This occurs at certain operating conditions and is characterized by an increasing amount of liquid not following the movement of the shaking table, thus reducing the specific power consumption. This, of course, has much relevance for practical work with microbial cultures. The phenomenon of being "out-of-phase" is described in the form of a newly defined nondimensional phase number (Ph) in analogy to a partially filled, rotating horizontal drum. The Ph can be used to determine reasonable operating conditions for shaking flask experiments when using viscous media, avoiding unfavorable "out-of-phase" operation.

Biotechnology↗
PubMedDate not supplied

[Food consumption and the nutritional status of schoolchildren of the Community of Madrid (CAENPE): general methodology and overall food consumption. Consumo de alimentos y estado nutricional de la población escolar].

The CAENPE study (Food Consumption and Nutritional State of the School Population) was a transversal observational study funded and promoted by the Directorate-General of Food Hygiene in the Ministry of Health, implemented in 1991-93, with the main aim of quantifying food consumption in the school population (6-14 years of age) in the Regional Community of Madrid, together with an anthropometric study and nutritional analysis of that population. This project sets our the General Methodology for the study, paying particular attention to the sampling design, to ensure that the sample is representative of the community, and the results of the overall consumption of food and its comparison with recommended diet and other population studies. Quantification shows a high and rising consumption of meat, meat products, sweets, snacks and prepared dishes, suitable consumption of eggs, legumes and fruit and a notable lack of greens, vegetables and potatoes. The basic results underline the need to introduce educational measures with practical effect on home and school menus.

Adolescent↗
PubMed1996

[The consumption of food of animal origin distinct from milk: meat, fish, eggs in the school-age population of the community of Madrid. The Food Consumption and Nutritional Status of the School-Age Population of the Autonomous Community of Madrid Group].

The aim of this study was to assess the intake of foods of animal origin other than milk, as well as their role in the diet of children, in a representative sample of a school-aged population from the Community of Madrid (CAENPE study). A 4 day assessment of the dietary intake was conducted by applying a combination of the methods of 24-hour recall and a written record of the estimated consumption. We studied 2,608 schoolchildren between the ages of 6 and 14 years. The subjects were divided into groups according to age and sex. We found that the average meat intake was 213 +/- 87 g/person/day. The consumption of meat was significantly higher in boys (p < 0.05) and increased with age both in boys (p < 0.001) and girls (p < 0.05). Meat provided 40% of the saturated fat, 34% of the cholesterol and 33.5% of the protein in the diet. Fish intake was 77 +/- 64 g/person/day, with higher consumption in boys (p < 0.05) and with no influence of age. Fish supplied 11% of the dietary protein and only 1.2% of the saturated fat. Egg consumption was 31 +/- 20 g/day/person, which represents 3 eggs per week. The consumption of eggs was also higher in boys than in girls (p < 0.05) and provides 28% of the dietary cholesterol. We conclude that meat provides more than one third of the dietary protein and alone covers the RDA for protein. In addition, meat also contributes the highest amount of dietary saturated fat and cholesterol. Egg and fish intake is adequate; hence, it would be desirable to reduce the excessive meat intake in order to equilibrate the macronutrients and cholesterol supplied by the diet.

Adolescent↗
PubMed1997

[Trends in alcohol consumption and predictors for increased alcohol consumption in former East Germany--analysis of the 1st and 2nd stages of the German Cardiovascular Prevention Study].

In comparison to other European and western countries, the social epidemiology of alcohol consumption and alcohol abuse in the general population remains under-researched in Germany. In an attempt to begin to fill this gap, data sets from the German Cardiovascular Prevention Study (DHP), now available as public use files, are analysed. The goals of the present study are: (1) to investigate the data sets from the first and second stages of the DHP (1984, 1987) for possible trends in drinking patterns in the German general population, and (2) through use of logistic regression, to identify sociodemographic correlates of heavy drinking. The frequency of consumption of various types of alcoholic beverages declined slightly to moderately among both men and women between 1984 and 1987. The percentage of persons who drank alcohol also declined. Mean consumption of alcohol remained basically unchanged between the two points: about 30 g per day for men and about 13 g per day for women. The second goal of the research was to identify sociodemographic correlates of heavy drinking. It was found that women of a particular age group, 30-39 years, are inclined to be heavy drinkers in comparison to women of other ages. Also among women, higher socioeconomic status showed a positive relationship to heavy drinking: however, income showed a negative influence. Only through the interactions with age and with level of secondary education was income positively related to heavy drinking. Among men, those with four children or more showed greater odds to be heavy drinkers. But the odds for heavy drinking decline among older men who live with their partners, while the odds for heavy drinking are higher for older men who live alone. The chances of being a heavy drinker are also considerably higher for employed men in comparison to men not employed; however, employed men of higher socioeconomic status have reduced odds of being heavy drinkers. These findings suggest that the research results from other countries with regard to predictors of heavy drinking may not be entirely applicable to the German general population. In any case, more detailed research into the social epidemiology of alcohol consumption in Germany is warranted. New and more specific knowledge can then be used to help develop public health measures for certain population subgroups who are identified as being at risk for alcohol abuse or alcohol problems on account of their heavy alcohol consumption.

Adult↗
PubMed1995

Changes in cerebral oxygen consumption are independent of changes in body oxygen consumption after severe head injury in childhood.

This study examines the relation between cerebral O2 consumption (CMRO2) and the O2 consumption of the rest of the body (BVO2) after severe head injury. Seventy nine serial measurements of whole body O2 consumption, CMRO2, plasma adrenaline, T3, and glucagon concentrations were made in 15 children with severe head injuries receiving neurointensive care. Body O2 consumption was measured with indirect calorimetry and CMRO2 with the Kety-Schmidt technique. There was no evidence of a significant relation between CMRO2 and BVO2. Within each child there were statistically significant positive relations between BVO2 and adrenaline, T3, and glucagon. By contrast, there was only a weak significant positive relation between CMRO2 and T3. In conclusion, CMRO2 and BVO2 seem to be determined independently after severe head injury. Thus therapeutic measures aiming to reduce CMRO2 need to be specific to the brain and it should not be assumed that measures which decrease whole body energy expenditure will necessarily have the same effect on CMRO2.

Adolescent↗
PubMed1979

[Methodological bases of the nutritional-physiological assessment of the per capita consumption of foods. I. Recording and characterization of the per capita consumption].

Per capita consumption indices are reference points essential to the provision of foods and the planning of food consumption. From them global statements regarding the energy and nutrient supply can be deduced. But this requires the exact definition of the per capita consumption indices with regard to the recording level, subitems and average losses. The mode of calculation and the assortment of each of the presented food groups are characterized in detail and estimate values for the occurring losses are indicated which are needed for the nutritional-physiological balancing of the per capita consumption indices.

Diet↗
PubMedDate not supplied

The effect of single serving versus entire package nutritional information on consumption norms and actual consumption of a snack food.

OBJECTIVE: Increasing serving sizes have been identified as contributors to the obesity epidemic. Researchers suggest that consumers are in need of cues that provide norms for the appropriate amount of food to consume. The impact of one potential cue, the provision of nutritional information for a single serving as well as the entire package ("dual-column labels") versus single-serving nutritional information only ("single-column labels"), was investigated on the consumption of a snack food for dieters and nondieters. DESIGN: In a between-subjects experimental design, participants were provided with a snack food product and nutrition label. After the opportunity for consumption, they were provided with a survey instrument. SETTING: The study took place in a classroom setting. PARTICIPANTS: Undergraduate students were randomly assigned to the single-column versus dual-column label treatment groups and were classified as dieters (n = 45) or nondieters (n = 67) based on self-reported dieting behavior. INTERVENTION: Participants were exposed to either a single-column or dual-column nutrition label. MAIN OUTCOME MEASURES: Perceptions of consumption norms; use, importance, and understanding of nutrition labels; and the actual amount consumed by each individual were measured. ANALYSIS: Analysis of variance was used to analyze data from the study. RESULTS: Nondieting participants, but not dieting participants, ate significantly less when exposed to the dual-column label compared to the single-column label (P < .05). Although there was a significant difference in the amount consumed by dieters and nondieters in the case of the single-column label (P < .05), the presence of a dual-column label attenuated this effect. In addition, dieters reported paying greater attention to (P < .01), better perceived the necessity of (P < .01), and had better understanding of (P < .05) label information than nondieters. In addition, dieters considered the provided serving to be more adequate than nondieters (P < .05). IMPLICATIONS FOR RESEARCH AND PRACTICE: Compared to standard, single-column labels, dual-column nutritional labels have a greater impact on the snack food consumption of nondieters.

Adult↗
PubMed1989

The relationship between alcohol consumption and social status in Stockholm. Has the social pattern of alcohol consumption changed?

Data from the Stockholm Health of the Population Study in 1984 (n = 6217) show small differences in mean alcohol consumption and in the prevalence of high consumers in various socioeconomic and educational categories of both sexes. Among young people mean consumption was higher in those who had low formal education, equal to 18.8 g 100% ethanol among men aged 18-24 years and 5.9 g for those with public elementary school education, while the corresponding figures for young women were 16.7 and 1.8 g respectively. Those reporting a high alcohol consumption (greater than or equal to 35 g 100% ethanol/day among men and greater than or equal to 25 g among women) had a relative risk over 7 of having been inpatients with alcohol-related diseases during 1980-1984. Our results, together with other recent Swedish survey data, indicate a change in the socioeconomic distribution of alcohol consumption over time. This change is analysed in relation to Swedish alcohol policy, changes in various socioeconomic categories, and the increase in information about alcohol.

Adolescent↗
PubMed2001

Consumption of a solid fat rich in lauric acid results in a more favorable serum lipid profile in healthy men and women than consumption of a solid fat rich in trans-fatty acids.

Solid fats are used in food manufacturing to provide texture and firmness to foods. Such fats are rich in either saturated or trans-fatty acids, both of which increase the risk of coronary heart disease. Epidemiological and experimental studies suggest that trans-fatty acids increase risk more than do saturates because they lower serum high density lipoprotein (HDL) cholesterol. However, there appear to be differences between saturates in their effect on HDL cholesterol. We investigated whether the consumption of a solid fat rich in lauric acid (C12:0) would result in a more favorable blood lipid profile than the consumption of a solid fat rich in trans-fatty acids. We fed 32 healthy men and women two controlled diets in a 2 x 4-wk randomized crossover design. The diets consisted of a background diet supplemented with margarines. In the trans-diet, 9.2% of energy was provided by trans-fatty acids and 12.9% by saturated fatty acids. In the Sat-diet, energy intake was 0% from trans-fatty acids and 22.9% from saturated fatty acids. Lauric acid composed one third of all saturates in the Sat-diet. Serum HDL cholesterol was 0.36 mmol/L lower at the end of the trans-diet than at the end of the Sat-diet (95% confidence interval, -0.46 to -0.26), whereas serum low density lipoprotein cholesterol and triglyceride concentrations remained stable. Serum total cholesterol was 0.31 mmol/L (95% confidence interval, -0.48 to -0.14) lower at the end of the trans-diet than at the end of the Sat-diet. Consumption of a solid fat rich in lauric acid gives a more favorable serum lipoprotein pattern than consumption of partially hydrogenated soybean oil rich in trans-fatty acids. Thus, solid fats rich in lauric acids, such as tropical fats, appear to be preferable to trans-fats in food manufacturing, where hard fats are indispensable.

Adolescent↗
PubMed2005

Relationship between ethanol consumption level and lifestyle status: excessive ethanol consumption can account for the prevalence of lifestyle-related diseases.

BACKGROUND: Diseases caused by unhealthful lifestyles, namely lifestyle-related diseases demands prompt solutions including preventive measures and effective treatment, especially in the developed countries. To that effect, clear understandings of such syndromes are required. Our recent observations have indicated that insulin resistance could, at least in part, account for the pathogenesis of lifestyle-related diseases. The aim of this study was to clarify whether excessive ethanol consumption could also be another cause of such diseases. METHOD: Lifestyle status was assessed based on Breslow's questionnaires of lifestyle index in 519 Japanese males aged 30 to 65 years. Averaged ethanol consumption level was determined by additional questionnaires and insulin resistance level was estimated by homeostasis model assessment. RESULTS: Ethanol consumption level was inversely associated with the total score on Breslow's lifestyle index. Improper drinking manner was associated with improper habit of smoking and proper habit of eating snacks among six lifestyle factors induced in Breslow's index. CONCLUSION: Subjects with more unhealthful lifestyles consumed greater amount of ethanol, suggesting that excessive ethanol consumption could be one of causes of lifestyle-related diseases. In addition to insulin resistance syndrome, alcohol-related diseases should be cared to address the issues of lifestyle-related diseases.

Adult↗
PubMed1986

Alcohol availability, alcohol consumption and alcohol-related damage. I. The distribution of consumption model.

One of the major approaches to alcoholism prevention is referred to as the distribution of consumption model. This prevention model can be summarized as a causal model whereby the availability of alcoholic beverages has a direct causal effect on the aggregate level of alcohol consumption in the population and, in turn, an indirect effect on the incidence and prevalence of alcohol-related damage. This article summarizes an application of a statistical technique known as the analysis of linear structural relations (LISREL) to a set of Ontario data concerning alcohol availability, alcohol consumption and alcohol-related damage. Results substantiated the existence of specific causal paths consistent with the model. Several procedures for assessing the overall goodness-of-fit of the model suggested that it adequately fit the data. The results provide reasonable statistical evidence that government policies restricting the retail availability of alcoholic beverages will reduce the per capita rates of alcohol consumption and, in turn, reduce the level of alcohol-related mortality and morbidity in the general population.

Adult↗
PubMed1997

[The consumption of psychoactive substances by adolescents in schools in Ribeiräo Preto, SP (Brazil). I--Prevalence of consumption by sex, age and substance].

INTRODUCTION: Concern over the consumption of psychoactive substances by teenagers has given rise to a great worldwide effort to produce information about this phenomenon. This study set out to investigate the prevalence of consumption of legal and illegal psychoactive substances, its distribution by age, sex and age at first experience of them, among teenage pupils in county, Ribeirão Preto, SP, Southeastern Brazil. MATERIAL AND METHOD: A self-applicable questionnaire duly adapted and submitted to a reliability test was applied to a proportional sample of 1,025 teenagers enrolled in 8th, 9th, 10th and 11th grades at public and private city schools. The questionnaire contained questions about the use of ten classes of psychoactive substances, demographic questions and validation information, as well as questions about the perception and intrinsic behavior related to drug consumption. RESULTS: The sample of 88.9% had consumed alcoholic beverages sometime in their lives, 37.7% had used tobacco, 31.1% solvents, 10.5% medicines, 6.8% marihuana, 2.7% cocaine, 1.6% hallucinogens, and 0.3% of the sample had consumed some opiate substance. The rates of consumption increased with age for all substances; however, the use of tobacco and of illegal substances was less intense during the later years of adolescence. As to sex distribution, boys consumed more than girls, except for medicines, with girls consuming barbiturates, amphetamines and tranquilizers in proportions similar to or higher than those observed among boys. Age at first experience showed that access to psychoactive substances occurred at very early ages. CONCLUSIONS: Experimenting with psychoactive substances, whether legal or illegal, is a frequent phenomenon during adolescence, both among boys and girls, often at very early ages.

Adolescent↗
PubMedDate not supplied

Randomized trial of a brief dietary intervention to decrease consumption of fat and increase consumption of fruits and vegetables.

PURPOSE: This study tested the efficacy of a computer-assisted counseling intervention to reduce diet-related cancer risk. DESIGN: Randomized controlled trial. SUBJECTS: Healthy women HMO members (n = 616) aged 40 to 70. INTERVENTION: Participants were randomly assigned to nutrition intervention or an attention-control intervention unrelated to diet. Intervention consisted of two 45-minute counseling sessions plus two 5- to 10-minute follow-up telephone contacts. Counseling sessions included a 20-minute, interactive, computer-based intervention using a touchscreen format. Intervention goals were reducing dietary fat and increasing consumption of fruit, vegetables, and whole grains. MEASURES: Twenty-four hour diet recalls and the Fat and Fiber Behavior Questionnaire (FFB). RESULTS: Four-month follow-up data were collected from 94% of the intervention participants and 91% of the controls. Testing with a multivariate general linear models analysis showed improvements on all dietary outcome variables. Compared to the control, intervention participants reported significantly less fat consumption (2.35 percentage points less for percentage of energy from fat), significantly greater consumption of fruit and vegetables combined (1.04 servings per day), and a significant reduction in a behavioral measure of fat consumption (.24 point change in the FFB). CONCLUSIONS: These 4-month results are comparable to several other moderate-intensity studies showing that, in the appropriate circumstances, moderate-intensity dietary interventions can be efficacious. Study limitations include the short follow-up period and the use of self-reported outcome measures.

Adult↗
PubMed1997

Calculated versus measured oxygen consumption during and after cardiac surgery. Is it possible to estimate lung oxygen consumption?

BACKGROUND: Lung tissue is metabolically active and consumes oxygen. The oxygen content difference between arterial and mixed venous blood does not include the effect of pulmonary tissue oxygen uptake. Thus, oxygen consumption (VO2) of the lung should be reflected as a difference between VO2 measured by gas exchange and VO2 derived by the Fick principle. The purpose of this study was to measure in clinical conditions this difference (taken to represent the VO2 of the lung), and to evaluate the sources of error in lung VO2 estimation. METHODS: Nine patients undergoing coronary artery bypass grafting were studied. VO2 was measured by indirect calorimetry (VO2gasex) and compared to Fick-derived VO2 (VO2Fick) after induction of anaesthesia, after closure of the chest, at admission to intensive care, after stabilization of haemodynamics and during weaning from mechanical ventilation. The Fick-derived VO2 was calculated from blood samples taken at the beginning and at the end of each 20 min measurement period, and the mean of 12 consecutive thermodilution cardiac output measurements taken during each 20 min measurement period. RESULTS: VO2gasex was higher than VO2Fick (P < 0.01; in all except 4 of 45 measurements). The difference between the measured and the calculated VO2 was 33 +/- 25 ml/min (mean +/- SD, range -16-100 ml/min). This difference represented 14 +/- 3% (range 11-18%) of the whole body VO2. The VO2-difference was highest after the induction of anaesthesia (50 +/- 19 ml/min; range 20-41 ml/min, P < 0.03) and lowest on arrival at the intensive care unit (10 +/- 16 ml/min; range -16-39 ml/min). Core temperature did not correlate with the oxygen consumption difference. CONCLUSIONS: A constant difference between measured and calculated VO2 can be detected in carefully controlled clinical conditions. The difference between the two methods is due to both lung oxygen consumption and errors in the measurement of VO2 thermodilution cardiac output, haemoglobin and blood oxygen contents. We suggest that the perioperative changes of the VO2-difference are due not only to variation of the measurements but also to changes in lung metabolic activity.

Adult↗
PubMed1998

Measurement of cerebral oxygen consumption in the human neonate using near infrared spectroscopy: cerebral oxygen consumption increases with advancing gestational age.

Measurements of cerebral oxygen consumption (CVO2) may improve our understanding of cerebral oxygenation, but there are few published data for sick neonates. Although cerebral maturation is associated with an increase in cerebral glucose consumption, the relationship between CVO2 and increasing gestational age has not previously been assessed in humans. The aims of this study were to evaluate a noninvasive method for the estimation of CVO2 in the neonate using near infrared spectroscopy, and to investigate the relationship between gestational age and CVO2. Twenty babies who were undergoing intensive care in the neonatal period were studied. Cerebral hemoglobin flow (CHbF) and cerebral venous oxyhemoglobin saturation (CSVO2) were measured using near infrared spectroscopy. Arterial oxyhemoglobin saturation was measure by pulse oximetry (SpO2). CVO2 was calculated from the equation: CVO2=CHbF x (SpO2 - SvO2 x 4. The median (range) CVO2 was 0.9 (0.52-1.76) mL x 100 g(-1) min(-1). There was an increase in CVO2 with advancing gestational age (n=20, p=0.55, p=0.014). We conclude that CVO2 can be estimated in sick neonates using noninvasive optical methods. The values obtained are similar to those obtained in other studies by more invasive methods, and are in agreement with values which would be expected from the known rate of cerebral glucose consumption in neonates. Mean (SD) CVO2 at 24-26 wk was 0.5 (0.18) mL x 100 g(-1) min(-1) and rose with increasing gestation to term by 0.03 mL x 100 g(-1) min(-1) per wk.

Anticonvulsants↗
PubMed1989

The pancreas and oxygen consumption (Part 2). Steroids do not modify resting pancreatic oxygen consumption in dogs: a preliminary report.

In order to evaluate the effect of methylprednisolone sodium succinate (MPSS) on the alteration of pancreatic oxygen consumption (VO2) in hypovolemic shock, MPSS was administered to four normal canines and three hypovolemic animals. All were treated according to the protocol used in the initial report. (The Pancreas and Oxygen Consumption 1: Pancreatic Oxygen Consumption in Normo- and Hypovolemic Dogs.) All seven underwent a splenectomy at the beginning of the experiment. Pancreatic VO2, obtained by adding up VO2 for the head (minus the uncinate process) and tail of the pancreas, was equal to the product of regional blood flow, Q, determined electromagnetically on the gastroduodenal (GDA) and splenic (SA) arteries, times O2 extraction, (a-v)O2; O2 content (in mL%) was measured in the femoral artery (RFA), in the splenic (SV) and superior pancreaticoduodenal (SPDV) veins. Similar determinations were carried out on the right hind limb that served as a control. Recordings were made for 4 h in both groups, the first hour determinations (five in all) serving as reference values. Methylprednisolone did not appear to alter pancreatic VO2, which showed a significant increasing trend from + 77% 1 h after MPSS had been given, to + 98% 3 h later (vs + 56 and + 92%, respectively, in the control group). As in the control group, these increases were owing to augmented O2 extraction by the pancreas. No significant change was noted between the head and tail of the pancreas. In the hind limb, VO2 increased significantly the first 2 h and differed from control VO2 at the end of the first hour only.

Animals↗
PubMed2000

Power consumption in shaking flasks on rotary shaking machines: I. Power consumption measurement in unbaffled flasks at low liquid viscosity.

In this first article of a series a new method is introduced that enables the accurate determination of the power consumption in a shaking flask. The method is based on torque measurements in the drive and appropriate compensation of the friction losses. The results for unbaffled shaking flasks at low viscosities are presented after varying shaking frequency, flask size, filling volume, shaking diameter, and surface quality (hydrophilic and hydrophobic) of the inner flask walls. The order of magnitude of the values of power consumption in shaking flasks is equal to, or even higher than, the values typical for agitated tank bioreactors. A physically based model equation for shaking flasks is derived that introduces a modified power number and a resulting constant as the only fitting parameter. With this equation, the measured results are correlated with sufficient accuracy. For the first time, comprehensive data for the power consumption in unbaffled shaking flasks at low viscosity is available, giving a detailed picture of the influences of the different variables.

Biotechnology↗
PubMed1994

Effects of chronic phenylpropanolamine infusion and termination on body weight, food consumption and water consumption in rats.

The present study determined the effect of chronic PPA infusion and withdrawal on weight regulation. Male Sprague-Dawley rats received PPA (0, 90 or 180 mg/kg) via miniosmotic pumps for 2 weeks. Body weight and food and water consumption were measured daily before, during, and for 2 weeks after PPA infusion. Additionally, body weight was measured once 6 weeks after the last day of drug administration. PPA infusion produced dose-dependent reductions in body weight and food consumption throughout drug administration. During the first week of PPA termination, food consumption returned to control levels; however, body weights of drug-treated animals remained below those of controls throughout the 6-week post-drug period. PPA depressed water intake during the first week of drug administration, but tolerance to this effect developed by the second week of administration. These results suggest chronic PPA infusion produces persistent appetite suppression and weight loss and that discontinuation of PPA does not result in hyperphagia or rapid weight gain. These findings may have clinical significance for the many individuals who wish to lose weight but have difficulty reducing intake without pharmacologic assistance.

Animals↗