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Results for “Comparative immunology”

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PubMedDate not supplied

[Comparative immunological study of protein extracts of poisonous and non-poisonous fishes (author's transl)].

Suggesting an immunologic participation in the pathogeny of the ciguateric syndroms, the authors have prepared a proteic antigen from the flesh of poisonous and edible fish of the same species. They have shown that there is a total common antigenicity between toxic and non toxic extracts. They suggest a new immunologic approach, in the matter of intoxication by ciguateric fish.

Animals↗
PubMed2003

Comparative immunological recognition of proteins from New Guinea "C" dengue virus type 2 prototype and from a dengue virus type 2 strain isolated in the State of Rio de Janeiro, Brazil.

The protein profiles of the New Guinea "C" dengue virus type 2 (DENV-2)prototype and those of a Brazilian DENV-2 isolated in the State of Rio de Janeiro in 1995 were compared. SDS-PAGE analysis showed that the virus from Rio de Janeiro expresses NS5 (93.0 kDa), NS3 (66.8 kDa) E (62.4 kDa) and NS1 (41.2 kDa) proteins differently from the New Guinea "C" virus. The immunoblot revealed specificity and antigenicity for the NS3 protein from DENV-2 Rio de Janeiro mainly in primary infections, convalescent cases, and in secondary infections in both cases and only antigenicity for E and NS1 proteins for both viruses in primary and secondary infections.

Animals↗
PubMedDate not supplied

Acquired immune deficiency syndrome (AIDS): speculations about its etiology and comparative immunology.

Acquired immune deficiency syndrome (AIDS) in many aspects resembles formerly recognized immune deficiencies, but in its complexity and presumed viral etiology, it is a unique entity. Examples of overlapping features of AIDS and immune defects, infectious complications, and neoplasms are discussed. It is not known what are the exact underlying mechanisms that permit or prohibit infectious and neoplastic complications among the immunodeficiency syndromes compared, but both overlapping and differing features of these entities are significant enough to hold a clue for future understanding. AIDS resembles feline leukemia as this latter syndrome was described 10 years ago. The retrovirus causing feline leukemia is highly immunosuppressive; preleukemic and viremic cats often succumb to opportunistic infections. If patients with early AIDS harbor retroviruses related to the human T cell leukemia virus in their organs (lymph nodes, bone marrow), serotherapy with monoclonal antibodies directed to this virus may stop and reverse the severe immunosuppression, thus preventing the development of opportunistic infections.

Acquired Immunodeficiency Syndrome↗
PubMed1982

[Comparative immunologic studies in PUVA and SUP (selected ultraviolet phototherapy) treatments].

10 PUVA and 13 SUP-treated psoriatic patients were examined immunologically. The proportion of sheep and mouse erythrocyte rosette forming lymphocytes, the leucocyte migration inhibitory assay, the lymphocyte transformation test were carried out and the suppressor function of peripheral blood mononuclear cells was measured before and 48 hours after the clearing of lesions. The results observed before and after the treatment were compared to each other and to the values of healthy volunteers. No significant difference was observed between the results obtained before and after the treatment, meaning that the immune alterations, which have been observed by several authors immediately after PUVA therapy or UV light irradiation, were not detectable if the tests wer made 48 hours later than the last treatment. The significantly decreased suppressor function of peripheral blood mononuclear cells was not changed during the therapy either.

Cell Migration Inhibition↗