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PubMed1989

Persistent urticaria caused by a common coloring agent.

As this case illustrates, foods or drugs may be ignored as possible causes of urticaria when they are not commonly accepted offenders or when they previously have been consumed with no adverse effect. In some instances, an additive or dye in a food or drug may be responsible for the reaction. In addition, a change of brands or dosage form of a drug may provoke urticaria or other reactions in sensitive individuals.

Azo Compounds↗
PubMed1987

[The analysis of caramel colors. 1. Differentiation of classes of caramel coloring agents with Curie-point pyrolysis-capillary gas chromatography-mass spectrometry].

After an introduction on the production, classification, legislative regulations, toxicology, and analysis of caramel colours, a report is given on the examination of these colourings by Curie-point pyrolysis-capillary gas chromatography-mass spectrometry. This method enables the differentiation between the four classes of caramel colours on the basis of the most concentrated of more than 100 identified pyrolysis products, which requires small quantities of substance (100 micrograms) and short periods of time (1 h).

Carbohydrates↗
PubMedDate not supplied

[Mutagenic effect of the food-coloring agents tartrazine and indigo carmine].

The authors studied the mutagenic action of the food dyes, tartrazine (both Soviet and imported) and indigocarmine in a microbial model and in warm-blooded animals (linear mice). Determined the toxicity and mutagenic action of the dyes on E. coli, strain K-12, carried out chromosomal analysis of the bone marrow, examined the dominant lethals in CBA X C57BL/6 mice. The recommended daily dose amounts to 400 mg/kg for tartrazine and to 50 mg/kg for indigocarmine with regard to the safety factor equal to 100. The data derived as a result of studying the mutagenic activity of tartrazine manufactured in the USSR and CSSR and indigocarmine paste in 3 experimental models allow the conclusion to be made that the doses of these dyes applied in food industry are fairly safe.

Animal Feed↗