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At least 55 records · Page 3Linked to original sources
PubMed2001

Combined toxicity of Cassia senna and Citrullus colocynthis in rats.

Body weight loss, inefficiency of feed utilization, diarrhea, ruffled hair and enterohepatonephrotoxicity were effects on male Wistar rats fed diet containing 10% Cassia senna or 10% Citrullus colocynthis ripe fruits for 6w. Rats fed a 1:1 mixture (5% + 5%) of fruits from these plants were more adversely affected and had deaths than rats fed the individual plants. The changes associated with the macrocytic hypochromic anemia and leukopenia were increased serum AST, ALT and ALP activities, increased urea, and decreased total protein, albumin and calcium. Serum bilirubin concentration did not change.

Alanine Transaminase↗
PubMed2003

Antibacterial screening of Citrullus colocynthis.

Crude ethanolic extracts of fruits, leaves, stems and roots of Citrullus colocynthis Schrad were examined for their antibacterial potentialities against Gram positive and Gram negative bacilli. Ethanolic extracts of fruits, leaves, stems and roots were found to be active against Gram positive bacilli, viz., Bacillus pumilus and Staphylococcus aureus, while fruit and root extracts in double strength gave positive results against Gram positive bacillus (Bacillus subtilis). The Gram negative bacilli viz., Escherichia coli and Pseudomonas aeruginosa showed no response.

Journal Article↗
PubMed1989

Toxicity of colocynithin and hydrated colocynithin from alcoholic extract of Citrullus colocynthis pulp.

The comparative toxicity of the alcoholic extract of Citrullus colocynthis pulp; colocynithin and hydrated colocynithin have been isolated and tried against seven insect species. The American cockroaches were more susceptible for both compounds than the German one, adult honey bee were more affected with Colocynithin than adult housefly. while hydrated colocynithin was more toxic to housefly than honey bee, cotton leafworm was less affected with both toxicants. Bed bug was less affected with Colocynithin than mosquito, but V.V. with hydrated Colocynithin. A direct parallel relation was found between toxicity and rate of penetration.

Animals↗
PubMed1984

The effect of Citrullus colocynthis on sheep.

Fresh Citrullus colocynthis fruits and leaves were fed to ten sheep at daily doses ranging from 0.25 to 10 g/kg. The sheep showed signs of poisoning and died from 4 hours to 25 days after dosing. The clinical signs of diarrhea, anorexia, dyspnea and loss of condition were well correlated with the pathological findings. There was an increase in the concentrations of creatinine, urea and potassium and a decrease in total protein and calcium in the serum and in the blood sugar level of Colocynthis-poisoned sheep. Changes in the concentrations of serum phosphorus and magnesium were inconsistent. Hematological changes indicated the development of hemoconcentration. Leucocytosis resulted from an increased number of neutrophils.

Animals↗
PubMed2004

Ethylene-induced gene expression, enzyme activities, and water soaking in immature and ripe watermelon (Citrullus lanatus) fruit.

Watermelon fruit exhibit acute softening and placental-tissue water soaking following short exposure to exogenous ethylene. Experiments were performed to address transcript abundance and activities of cell wall and membrane hydrolases in placental tissue in response to treatment of watermelon fruit with ethylene. Watermelon fruit were harvested at immature and full-ripe stages and exposed to 50 microL L(-1) ethylene for 6 days at 20 degrees C. Ethylene affected the abundance of transcripts for PME (EC 3.2.1.11), and alpha-(EC 3.2.1.22) and beta-GAL (EC 3.2.1.23) but these effects were dependent on fruit maturity and appeared not to be associated with the water-soaking syndrome. PG (EC 3.2.1.15) and EXP mRNAs accumulated significantly in response to ethylene exposure. Additionally, the levels of mRNA and activities of LOX (EC 1.13.11.12), PLC (EC 3.1.4.3) and PLD (EC 3.1.4.4) were elevated in fruit of both maturity classes exposed to ethylene and were temporally associated with the visible symptoms of water soaking. The activity trends and transcript abundance in ethylene- compared with air-treated fruit indicate that PG, EXP, LOX, PLC and PLD levels increase with the onset and development of the water-soaking disorder and support the view that catabolic reactions targeting the membranes and cell-walls contribute to the disorder.

Cell Wall↗
PubMed2006

Cucurbitacin glucosides from Citrullus colocynthis.

A new cucurbitacin glucoside 2-O-beta-D-glucopyranosyl-16alpha-20R-dihydroxy-cucurbita-1,5,23E,25(26)-tetraen-3,11,22-trione (1) has been isolated from the methanolic extract of the fruits of Citrulluscolocynthis. The structure has been assigned on the basis of spectral analysis including 1D and 2D NMR techniques. In addition 2-O-beta-D-glucopyranosyl-cucurbitacin B (arvenin I) (2) and 2,25-di-O-beta-D-glucopyranosyl-cucurbitacin L (3) are reported for the first time from this species.

Citrullus↗
PubMed2002

Resistance of Polish lines and hybrids of watermelon [Citrullus lanatus (Thunb.) Matsum et Nakai] to Fusarium oxysporum at the seedling stage.

Watermelon is a species cultivated in the hot climate or in the greenhouse. Since recently it has also started to be grown in the open in the Polish climate. This species is frequently at risk of Fusarium oxysporum infection. Between 1996 and 1997 ten inbred lines and nine hybrids of Polish origin were tested for resistance to this pathogen. The test was conducted with the use of four isolates of F. oxysporum: three from Polish infected plants (formae speciales not determined), while the fourth from U.K. (F. oxysporum f. sp. niveum). In the three series of tests the control plants were Pannonia F(1) and Sugar Baby. No inbred line or hybrid was found to be highly resistant to the pathogen. However, it was possible to identify four lines and five hybrids showing a higher level of resistance as compared with the control. The level of hybrid resistance was determined by comparison with the parental genotypes.

Citrullus↗