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Suicidal ingestion of barium-sulfide-containing shaving powder.

Physicians, familiar with the common usage of barium medicinally as the contrast agent barium sulfate, may consider it an innocuous or at most a minimally harmful compound. The barium cation is extremely toxic and produces characteristic gastrointestinal symptoms, periorbital and extremity paresthesia, hypertension, and progressive flaccid muscular paralysis. Profound hypokalemia also may be induced. Overdose may be rapidly fatal unless the ingestion is recognized and appropriate treatment is instituted expediently.

Adult↗

[Sensitivity of the prosobranch mollusk Potamopyrgus jenkinsi Smith to the action of metallic chlorides (ZnCl2, BaCl2, CuCl2) and to the synthetic molluscacide N-tritylmorpholine].

The toxicity of 3 metal chlorides (ZnCl2, BaCl2, CuCl2), and of N-trityl-morpholine (Triphenmorph or frescon) has been studied on the gastropod mollusc Potamopyrgus jenkinsi, in eucalcic and oligocalcic waters. The results showed the following order in the efficiency of the toxic compounds: triphenmorph greater than copper greater than barium greater than zinc. In eucalcic water, the toxicity of barium and decreased whereas the efficiency of triphenmorph and increased. The toxicity of the substances, at middle term, rose in relation to the time of the experiment. An exposure of 2 h to the toxic agents was sufficient to induce high mortality in P jenkinsi. In oligocalcic water, the juvenile snails were more sensitive than the adults to the action of metal chlorides, but they showed higher tolerance to Triphenmorph; in addition, the winter generation was more resistant than the summer one, except for barium.

Animals↗

Response to barium selenate supplementation in sheep kept at pasture in the Mediterranean area.

This work evaluated the efficacy of barium selenate supplements in the prevention of disorders related to Se deficiency in sheep maintained at pasture in the Mediterranean area. Ewes on five farms were divided into two equal groups of 1,750 animals: a) the treated group and b) the control group. The animals of the treated group were injected subcutaneously, in the first third of gestation, with a barium selenate compound at a dose of 1 mg Se/kg. The ewes in the control group did not receive any supplement of Se and/or vitamin E. The two groups were managed under the same feeding and husbandry practices throughout the experiment. After lambing, blood glutathione peroxidase (GSHPx) and serum aspartate aminotransferase (AST), creatine kinase (CK) and lactate dehydrogenase (LDH) activities were measured in the lambs born to both group. Blood GSHPx activity was higher in the treated animals, with statistically significant differences due to the response to injection of barium selenate. Mean global serum activities of AST and CK tended to be higher in the control group, as a consequence of the protection given to the treated group by the supplement, but the differences were not statistically significant. This was possibly due to the absence of clinical cases of nutritional myodystrophy (NMD) in the animals of the control group. Therefore it can be stated that barium selenate supplementation can prevent Se deficiency in sheep herds maintained at pasture in this area.

Animal Feed↗