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Results for “Admixture”

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PubMed1979

Reference aids for developing policies and procedures for intravenous admixture services.

A table of literature citations designed to help hospital pharmacists develop a policy and procedure manual for i.v. admixture services is presented. The table is categorized according to literature that will aid in developing policies and procedures for specific aspects of admixutre services (e.g., distribution procedures, quality assurance). The citations were selected from two periodicals (American Journal of Hospital Pharmacy and Drug Intelligence & Clinical Pharmacy) and three other publications.

Bibliographies as Topic↗
PubMedDate not supplied

[Admixtures of antibiotic substances in enzyme preparations of microbial origin intended for use as food additives].

A group of enzymtic preparations, mainly of the Soviet make were investigated for the presence of antibiotic substances admixtures. Altogether 25 preparations obtained from molds, actinomycetes, bacteria and yeast were studied. The results showed that 18 preparations contained antibiotic substances in an amount of 0.6-1300 U, equivalent to oxytetracycline units per 1 g. Most often antibiotics were present in preparations of the pectinase and protease group. In the group of glucoamylase the antibiotic activity was uncovered in a single preparation. Procedures employed in determining the antibiotic activity of enzymatic preparations is described and the possible role of antibiotics in the manifestations of their toxic properties discussed.

Actinomycetales↗
PubMed1977

[Component composition and admixtures of related compounds in commercial preparations with an erythromycin base].

Chromatographic purity of erythromycin base preparations manufactured in the USSR with various technological procedures and those of 4 foreign firms was studied. All the preparations studied in addition to the main component of erythromycin A contained 5 to 7 per cent of erythromycin C and about 1.5 to 3.5 per cent of a non-identified component possessing a somewhat lower chromatographic mobility than erythromycin C. The admixture of 0.5--1 per cent of anhydroerythmycin was found in many erythromycin preparations. The preparations of some foreign firms contained also a number of additional substances. It was shown that the antimicrobial activity of anhydroerythromycin was 50-60 times lower than that of erythromycin. Direct correla;ion between the level of the antimicrobial activity of the market prepaetions of erythromycin and the level of its chemical purity was noted.

Animals↗
PubMed2026

Genomic consequences of admixture in an experimentally founded sand lizard population.

Conservation interventions are increasingly required for species threatened by population declines and isolation due to anthropogenic pressures. Small, isolated populations are particularly vulnerable to the loss of genetic diversity, increased inbreeding, and the accumulation of deleterious mutations. Translocations or supplementation of allopatric individuals for genetic rescue may be the only way to increase genetic diversity and increase population persistence via increased adaptive potential. Here, we use an experimentally admixed population of sand lizards on a small island in Sweden as a valuable model of genetic rescue. This population was established approximately 20 years ago (5-6 generations), resulting in increased fecundity and hatchling viability. This population was founded from crossings between individuals from an inbred population from the nearby mainland and individuals sourced from populations in southern Sweden. Low-coverage whole-genome sequencing revealed elevated genetic diversity and reduced realized genetic load in this admixed population relative to the source populations. Ancestry analyses indicated a greater contribution of southern Swedish genetic variation, potentially reflecting the contribution of beneficial adaptive variation from this region that may underlie the positive population effects. This system provides valuable empirical insights into the long-term genomic consequences of genetic rescue in this model vertebrate population.

Journal Article↗
PubMed1977

Hypertension: effects of social class and racial admixture: the results of a cohort study in the black population of Charleston, South Carolina.

It has been hypothesized that genetic factors, as manifested by skin color, play in important role in the genesis of hypertension among Blacks. A community-based study was carried out in Charleston Country, South Carolina to test this hypothesis. The results of a ten year follow-up study suggest that social class and age were more consistently associated with the incidence of hypertension and levels of blood pressure. The association of hypertension with skin color was minimal and substantially less than that of social class. The incidence rate of hypertension (larger than or equal to 90 mm Hg) was three to four times greater when the study participants were of low social class than when they had higher social class scores at the beginning of this study. In contrast, the incidence rate was only 1.5 times higher for dark than for lighter skinned men, and the rates were almost identical when social class was comparable. Similar results energed when blood pressure was treated as a continuous variable; blood pressure levels and pressure changes over time were consistently and significantly (p less than .01) higher in those Blacks categorized as low social class, controlling for skin color.

Adult↗