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Abortion rate during the second half of gestation of cows undergoing surgery in lateral recumbency as compared with cows of a control population.

In a retrospective study, we compared the abortion rates of 59 cows in the second half of gestation, admitted to the Clinic for Food Animals and Horses (1993-1996) with a strictly focal problem (head region, udder and teats, locomotor system) requiring surgery in lateral recumbency, to the abortion rate of a control cow population. Before surgery, a uterus relaxant was given in 42 cases, and 17 cows were untreated as to pregnancy. Cows included in the reproduction health program of the Department of Fertility and Reproduction were used as a control population. Data of 1,736 cows pregnant in the second half of gestation per year were available for the same time period (1993-1996). Abortion rate was 5.08% for the cows undergoing surgery in lateral recumbency as compared with 5.18% for the cows of the control population. There was no significant difference between the two populations (P > 0.05). Thus, the risk for abortion in the cows in question is not elevated as compared with the control population.

Abortion, Veterinary↗

Contraception in The Netherlands: the low abortion rate explained.

This article gives a review of the main factors that are related to the low abortion rate in the Netherlands. Attention is payed to figures on abortion and the use of contraceptive methods since the beginning of the 1960s up to the end of the 1980s. The strong acceptance of family planning was influenced by changing values regarding sexuality and the family, the transition from an agricultural to a modern industrial society, rapid economic growth, declining influence of the churches on daily life, introduction of modern mass media and the increased general educational level. The introduction of modern contraceptives (mainly the pill and contraceptive sterilization) was stimulated by a strong voluntary family planning movement, fear for overpopulation, a positive role of GPs, and the public health insurance system. A reduction of unwanted pregnancies has been accomplished through successful strategies for the prevention of teenage pregnancy (including sex education, open discussions on sexuality in mass media, educational campaigns and low barrier services) as well as through wide acceptance of sterilization. The Dutch experience with family planning shows the following characteristics: a strong wish to reduce reliance on abortion, ongoing sexual and contraceptive education related to the actual experiences of the target groups, and low barrier family planning services.

Abortion, Induced↗

Spontaneous abortion rate in ultrasonographically viable pregnancies.

In a prospective study of 500 patients who had an ultrasonically viable pregnancy at less than 12 weeks' gestation, the spontaneous abortion rate was 2% overall. In those women with a history of spontaneous abortion, the abortion rate increased tenfold. Spontaneous abortion at less than ten weeks' gestation was up to three times higher than that at greater than ten weeks' gestation; this may have implications when deciding on the timing of first-trimester diagnostic procedures.

Abortion, Spontaneous↗

Spontaneous abortion rate and advanced maternal age: consequences for prenatal diagnosis.

Maternal age related and procedure-related fetal abortion rates were studied in 384 women aged 36 and over scheduled for transabdominal chorionic villus sampling (TA-CVS) at 12-14 weeks of gestation. The pre-TA-CVS abortion rate within 30 days of intake (at 6-10 weeks of gestation) rose from 1.9% at age 35-36 years to 10.9% at 40 years and older. Women entering in the 6th week of gestation had a greater probability of aborting before TA-CVS than women entering after day 48. 26 women aborted spontaneously before TA-CVS, the majority of abortions occurring at 10-12 weeks. TA-CVS was done in 346 women. 11 pregnancies were terminated because of genetic anomalies, and 8 women had spontaneous fetal loss. These findings justify delaying prenatal diagnosis in older pregnant women until 12 weeks of gestation.

Abortion, Spontaneous↗

The effect of sera antisperm antibodies in the female partner on in vivo and in vitro pregnancy and spontaneous abortion rates.

PROBLEM: To determine the incidence of antisperm antibodies (ASA) in female sera from infertile couples or those suffering from recurrent abortions. Also to determine if the pregnancy and/or abortion rates are any higher in those positive versus those negative for ASA. METHOD: All registered patients had sera drawn and ASA measured by indirect immunobead test on initial study. Pregnancy and abortion rates were determined for patients undergoing in vivo or in vitro therapy. RESULTS: There was a low incidence of ASA in patients having in vivo or in vitro treatment. There was no decrease in pregnancy rates (PRs) or increase in spontaneous abortions (SAB) in those positive for ASA. CONCLUSION: Antisperm antibodies in female sera do not seem to be etiologic in causing infertility or SAB. Future studies might consider changing the antigen source from donor sperm to husband's sperm.

Abortion, Habitual↗

Advanced provision of emergency contraception to postnatal women in China makes no difference in abortion rates: a randomized controlled trial.

Emergency contraception (EC) prevents pregnancy, and it has been suggested that widespread use could reduce abortion rates; however, the use is limited. Providing EC in advance of need increases use, but there is no direct evidence that it reduces unintended pregnancy. In a randomized controlled trial of 2000 women after childbirth in Shanghai, all women not wishing to use hormonal contraception or an intrauterine device (IUD) were given a supply of condoms. Those in the intervention group also received three courses of mifepristone 10 mg with instructions for use as EC. Follow-up was by telephone at 16, 32 and 52 weeks. Over 88% of women in both groups completed 1 year of follow-up. Women with a supply of EC were more than twice as likely to use it, and to use it more than once (p<.001 for both) than women without a supply. There was no difference in pregnancy rates at 1 year (38/832 vs. 32/817). EC was not used in 89% of conception cycles, as women did not recognize the need for it. Increased use of EC may not reduce abortion rates.

Abortion, Induced↗

Aging of endometrium and oocytes: observations on conception and abortion rates in an egg donation model.

OBJECTIVE: To assess the comparative contribution of endometrial and oocytic aging to the decline in fertility with age. DESIGN: Retrospective analysis of conception and abortion rates in an egg donation program, with respect to donor and recipient ages. PATIENTS: All oocyte recipients had ovarian failure. Donors were women undergoing in vitro fertilization who contributed up to a third of retrieved oocytes. INTERVENTIONS: None. RESULTS: Thirty pregnancies (28 intrauterine) were recorded in 169 reception cycles originating from 91 donation cycles. Women who conceived were younger than those who did not (median age 31 versus 37; P less than 0.046), with no difference in age of donors. There was a significant difference in spontaneous abortion rate by age of donor rather than by age of recipient. Donors to successful pregnancies were younger than donors to aborted pregnancies (median age 27.5 versus 33; P less than 0.0211), but the 11 women with aborted pregnancies did not differ in age from the 17 women with successful pregnancies. CONCLUSIONS: In women, endometrial function as expressed by conception rate in the recipients declines with age, whereas it is oocyte age that primarily influences risk of abortion.

Abortion, Spontaneous↗

Effect of a killed whole Neospora caninum tachyzoite vaccine on the crude abortion rate of Costa Rican dairy cows under field conditions.

A standard field trial was carried out to assess the effect of a commercial Neospora-vaccine based on whole killed tachyzoites (Bovilis-Neoguard, Intervet) on the abortion rate. Eight hundred and seventy-six cows, over 2.5 months pregnant, belonging to 25 Costa Rican dairy herds, were used in the analysis. For each cow vaccinated, a cow of the same herd, breed and age category, was selected as control. The period of administration of treatments extended from June to November of 2000. The treatments were administered in two, 5-ml doses 1 month apart, the first dose given between day 75 and 90 of gestation. The incidence of abortion among all treated cows was of 16.0% (140/876). The treatment specific incidence was 11.2% (49/438) and 20.8% (91/438) for the vaccinated and the placebo group, respectively. The prevented fraction by vaccination amounted to 0.46 (95% CI: 0.26, 0.61), and the cumulative incidence ratio for the vaccinated group was 0.54. The Cox hazard ratio was 0.51(95% CI: 0.37, 0.72), meaning that the force of abortion is reduced twice in the vaccinated group. The results of this study, the first one following this type of design, shows that the killed whole Neospora caninum tachyzoite preparation had a reasonable effect on the abortion rate in Costa Rican dairy cattle.

Abortion, Veterinary↗

Fertility and abortion rates in the United States, 1960-2002.

This paper provides a general overview of trends in the United States (US) birth, fertility and abortion data from 1960 to 2002. Rates by age, race and Hispanic origin are also discussed. Data presented in this paper are derived primarily from published reports of the US government's Centers for Disease Control and Prevention's National Center for Health Statistics. In 2002, there were 4,021,726 births in the US. The general fertility rate was 64.8 births per 1,000 women aged 15-44 years, the total fertility rate was 2013.0 children per 1,000 women, and the net reproduction rate was 968 daughters per 1000 women. These rates have declined in the US since 1960, down by at least 44% for all rates. While these rates have been declining, there are substantial differences in fertility patterns by age and race and Hispanic origin. Rates for women, 30 years of age and over, increased between 1980 and 2002. In contrast, rates for women under 25 years of age rose considerably during the late 1980s, and then decreased sharply since 1991. Rates for women in their late twenties (25-29 years of age), the principal childbearing ages, have fluctuated within a narrow range throughout this period (1980-2002). As a result of the increase in births to older women, the mean age of mother at first birth increased by nearly 4 years from 1968 to 2002. In 2000, the latest year for which data are available, there were 21.3 induced abortions per 1000 women aged 15-44 years, down from 27.4 in 1990. The total abortion rate, average number of legally induced abortions that would occur to a hypothetical cohort of 1000 women, was 672.0 abortions per 1,000 women in 2000, down from 785.5 in 1980. The abortion rate has declined fairly steadily since 1980. Like the birth and fertility rates, substantial differences in abortion rates exist by age and race and Hispanic origin. The rates of induced abortion increased for women in their thirties between 1980 and 2000, whereas rates for women under 25 years of age and women 40 years of age and over decreased since 1980. The rate for women 25-29 years of age changed little. The rate of induced abortion was considerably higher for non-Hispanic black women (57.4) in 2000 than for non-Hispanic white women (11.7). The rate for Hispanic women (30.6) was intermediate. The total abortion rate was also much higher for non-Hispanic black women than non-Hispanic white and Hispanic women.

Abortion, Induced↗

Estimating induced abortion rates: a review.

Legal abortions are authorized medical procedures, and as such, they are or can be recorded at the health facility where they are performed. The incidence of illegal, often unsafe, induced abortion has to be estimated, however. In the literature, no fewer than eight methods have been used to estimate the frequency of induced abortion: the "illegal abortion provider survey," the "complications statistics" approach, the "mortality statistics" approach, self-reporting techniques, prospective studies, the "residual" method, anonymous third party reports, and experts' estimates. This article describes the methodological requirements of each of these methods and discusses their biases. Empirical records for each method are reviewed, with particular attention paid to the contexts in which the method has been employed successfully. Finally, the choice of an appropriate method of estimation is discussed, depending on the context in which it is to be applied and on the goal of the estimation effort.

Abortion, Illegal↗

Concern rises over abortion rate in Sri Lanka.

Contraception is freely available in Sri Lanka, yet the number of illegal abortions is increasing. In Colombo alone over 500 abortions are performed daily, according to the minister of health, Dr. Ranjit Attapattu, who added in a recent statement that thix figure is "only the tip of the iceberg". The high abortion rate can be explained partly by the fact that although 99% of Sri Lanka's 7.5 million women know about family planning, only just over 1/2 of them practice any form of birth control. A government survey in 1982 showed that as many as 94% of women wanted to limit their families, and 80% of their husbands approved of birth control; most women wanted only 2 or 3 children. Abortions are illegal, except where the life of the mother is in danger, and they pose not only moral, cultural, and religious problems, but an economic problem as well. According to hospital records, in the past decade 259,085 pregnancies have been terminated illegally. In 1981 alone there were 30,552 illegal abortions. For Sri Lanka's hospital system, which provides treatment free of charge, the economic implications are serious. Doctors say that large numbers of gynecological beds have to be provided for these patients, with their treatment costing a minimum of US$35. Religious opinion, both Buddhist and Christian, is strongly opposed to any relaxation of the abortion laws, but government statements seem to indicate a loosening of attitudes. The Ministry of Plan Implementation, which is in charge of all matters relating to population control, had this to say in a recent report: "In the context of persisting social inequalities, to consider abortion from the moral point of view only seems unwarranted. Those who do so fail to consider the real social and economic factors involved. There is a need to formulate a startegy", the report continues, "which will safeguard the dominant values of Sri Lanka society, while giving the woman the choice to decide when she wantsa chhild. Abortion is a social problem to be acted upon rather than a condition which must be confronted with legal restrictions."

Abortion, Induced↗

Hormone-induced preimplantation Lyt 2+ murine uterine suppressor cells persist after implantation and may reduce the spontaneous abortion rate in CBA/J mice.

Immunoregulatory cells in the maternal uterine endometrium and decidua are thought to play an important role in ensuring the success of the semiallogeneic conceptus. Two phases of suppression have been described in pregnant mice. Prior to implantation, the hormonal changes triggered by mating activate or recruit a population of nonspecific Lyt 2+ suppressor cells that inhibit cytotoxic T lymphocyte generation: this suppression appears to wane at the time or implantation and 4-5 days after implantation, a non-T suppressor cell population activated or recruited by fetal trophoblast cells develops. In this paper we confirm the non-major histocompatibility complex specificity of the hormone-regulated preimplantation suppressor cell. We show that this activity persists in the uterus during the early postimplantation period where its suppressive activity is masked by an Fc-receptor-positive cell population recruited by the implanting embryo. The potential importance of the persisting suppressor cells is suggested by an increase in the rate of spontaneous abortion of DBA2-mated CBA/J mice following injection of monoclonal anti-Lyt 2+ antibody in the early postimplantation period.

Abortion, Veterinary↗