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Results for “hyperuricemia”

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PubMed1981

Potentiation of ampicillin skin reactions by allopurinol or hyperuricemia.

Of 4434 hospitalized medical patients who received ampicillin in the absence of allopurinol, 251 (5.9 per cent) developed a rash within 21 days of exposure. Of 252 patients who received ampicillin and allopurinol together, 35 (13.9 percent) developed a rash. The present data confirm the previously reported increase in rash frequency in patients who receive both ampicillin and allopurinol.

Allopurinol↗
PubMed1977

Hyperuricemia as a risk factor in coronary heart disease.

The subjects of this study were 290 hospital patients who were divided into 4 groups: acute myocardial infarction (100), cardiac ischaemia with angina but no infarction (50), white patients without evidence of coronary heart disease (70), and a group of South African black patients without detectable coronary heart disease (70). Mean serum uric acid (SUA) levels were 8,00 +/- 0,32 in the ischaemic group, 7,09 +/- 0,23 in the acute infarction group, 5,78 +/- 0,21 in normal black patients, and 5,75 +/- 0,21 in normal white controls. The differences in SUA levels between the ischaemic and infarction groups as compared with both control groups was highly significant (p less than 0,001). These differences were most striking in the females aged 60 years and over.

Age Factors↗