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En bloc resection of the temporal bone by the lateral approach in carcinoma of the middle ear associated with skull base infiltration with reference to the resection of the petrous apex.

En bloc resection of the temporal bone was performed by the lateral approach on two patients with carcinoma of the middle ear, which was associated with destruction in the temporal bone and tumor infiltration of the cranial base. In one of the patients, the petrous apex was resected along with the temporal bone.En bloc resection on the temporal bone with the petrous apex is believed to be difficult because the internal carotid artery (ICA), cavernous sinus, and the brainstem are adjacent to each other in the petrous apex. However, the intra- and extracranial surgical procedures by this approach allow resection of the temporal bone ranging from the anterior part including the petrous apex to the posterior part including the mastoid process, the dura of the middle and posterior cranial fossae, and the sigmoid sinus, without exposure of the tumor. Special attention should be paid to the procedural points of surgery, such as, exposure of the petrous ICA, bleeding from the petrous sinus, and dural suturing in the vicinity of the apex. With regard to surgical indication, it is important to determine whether tumor infiltration is confined to the temporal bone and the dura of the middle and posterior fossa. If tumor infiltration into the petrous ICA, the dominant side of sigmoid sinus and/or the inferior cranial nerve is observed, then indication for surgery should be determined in a more critical manner.

Journal Article↗

Use of the LandmarXtrade mark Surgical Navigation System in Lateral Skull Base and Temporal Bone Surgery.

Despite the widespread availability of surgical navigation devices, their use in lateral skull base and temporal bone surgery has been limited. Problems with current systems include difficulty of use and inadequate accuracy. We present a series of cases using the LandmarXtrade mark surgical navigation system as an adjunct for lateral skull base and temporal bone procedures. This infrared emitting diodes (IRED)-driven system has a post that carries the IREDs and bypasses the need to place the patient in a Mayfield head holder. This configuration allows greater mobility of the surgical field. Registration of the patient can include a combination of fiducial and anatomic landmarks that significantly increase accuracy compared to fiducial calibration alone. We introduced the use of the lateral process of the malleus as a landmark, thereby increasing accuracy within the temporal bone to a range of 0.9 to 1.5 mm. We used the system on encephaloceles, glomus tumors, meningiomas, and schwannomas, and revision surgery for chronic otitis media. It decreased operating time, allowed more effective use of "keyhole" approaches, and increased safety. As the availability and flexibility of these systems increase, their use should become the standard of care in revision temporal bone and lateral skull base procedures.

Journal Article↗

Chondroblastoma of the temporal bone involving the temporomandibular joint, mandibular condyle, and middle cranial fossa: case report and review of the literature.

Chondroblastoma is a highly destructive tumor, derived from immature cartilage cells, typically occurring in epiphyses of the long bones of adolescents and young adults. Those occurring in the temporal bone and TMJ area are likely to mimic TMJ symptoms. This report describes a unique case in which a chondroblastoma resulted in extensive destruction of the temporal bone, temporomandibular joint, mandibular condyle, and cranial base, including gross intracranial and extracranial involvement. With appropriate surgical management, the outcome for patients with chondroblastoma of the temporomandibular region is quite favorable. This case brings the total reported chondroblastomas to 59 in the temporal bone and eight in the mandibular condyle as of the date of submission of this article for publication.

Adult↗

Total temporal bone resection for squamous cell carcinoma.

Because of unsatisfactory results in treatment of malignant conditions of the temporal bone, a technique for total en bloc resection of the temporal bone and carotid artery was reported by Graham et al. in 1984. The procedure involves resection of the internal carotid artery, cranial nerves VI through XII, and structures adjacent to the temporal bone. Experience with two additional cases led to numerous modifications in the recommended procedure, as reported by Sataloff and Myers. Additional clinical experience with this technique and its complications has resulted in further modification. Additional pitfalls and specific changes in technique from previous reports are discussed in detail, including a new procedure to assure the adequacy of contralateral venous outflow.

Aged↗

A case of cervical metastases from temporal bone carcinoid.

BACKGROUND: Carcinoids are neuroendocrine tumors that typically occur in the gastrointestinal tract and lung and less frequently in the head and neck region. Whereas the metastatic potential of laryngeal carcinoid is well documented, only one case of metastasis of temporal bone carcinoid to the cervical lymph nodes has been reported. We present the case of a 55-year-old woman with cervical metastases almost 3 years after a primary diagnosis of temporal bone carcinoid. METHODS: The patient had undergone a subtotal petrosectomy for a temporal bone carcinoid and, 29 months later, revision surgery for a local recurrence. Four months later, multiple laterocervical swelling appeared, and the patient underwent modified radical neck dissection. RESULTS: Histologic examination after the neck dissection was suggestive of lymph node metastases from a carcinoid tumor. Immunohistochemical analysis of the lymph node metastases showed neoplastic cells positive for keratin, vimentin, chromogranin, and neuron-specific enolase and negative for thyroglobulin, calcitonin, S-100, and parathyroid hormone. The patient was treated with intensity-modulated radiation therapy and neck irradiation. CONCLUSIONS: We believe that temporal bone carcinoids have metastatic potential not predictable by histologic features. Surgical excision is the treatment of choice for patients with temporal bone carcinoids, with the approach and technique determined by the extent of the mass. Moreover, before planning surgery and during follow-up, neck node status must be carefully detected.

Carcinoid Tumor↗

Gunshot injuries to the temporal bone.

The current incidence of missile injury to the temporal bone (MITB) is very low in the United Kingdom. However, the increasing frequency of firearm violence in Britain suggests a greater risk of occurrence. This, along with the devastating potential sequelae of MITB (facial palsy, dead ear, intracranial damage, major vascular injury and cosmetic disfigurement), requires otolaryngologists to be conversant with all aspects of their management. The risk of major complications is much higher with MITB than with temporal bone injury following blunt trauma, and surgical management is, therefore, much more common. We present one such case, and review the literature outlining the pathogenesis, clinical features, and recommended management.

Adult↗

Digital volume tomography: radiologic examinations of the temporal bone.

OBJECTIVE: We evaluated the clinical applicability and the value of digital volume tomography for visualization of the lateral skull base using temporal bone specimens. MATERIALS AND METHODS: Twelve temporal bone specimens were used to evaluate digital volume tomography on the lateral skull base. Aside from the initial examination of the temporal bones, radiologic control examinations were performed after insertion of titanium, gold, and platinum middle-ear implants and a cochlear implant. RESULTS: With high-resolution and almost artifact-free visualization of alloplastic middle-ear implants of titanium, gold, or platinum, it was possible to define the smallest bone structures or position of the prosthesis with high precision. Furthermore, the examination proved that digital volume tomography is useful in assessing the normal position of a cochlear implant. CONCLUSION: Digital volume tomography expands the application of diagnostic possibilities in the lateral skull base. Therefore, we believe improved preoperative diagnosis can be achieved along with more accurate planning of the surgical procedure. Digital volume tomography delivers a small radiation dose and a high resolution coupled with a low purchase price for the equipment.

Cochlear Implantation↗

Virtual temporal bone dissection: an interactive surgical simulator.

OBJECTIVE: Our goal was to integrate current and emerging technology in virtual systems to provide a temporal bone dissection simulator that allows the user interactivity and realism similar to the cadaver laboratory. STUDY DESIGN: Iterative design and validation of a virtual environment for simulating temporal bone dissection. SETTING: University otolaryngology training program with interdisciplinary interaction in a high-performance computer facility. RESULTS: The system provides visual, force feedback (haptic), and aural interfaces. Unlike previous "fly through" virtual systems, this environment provides a richer emulation of surgical experience. CONCLUSION: The system provides a high level of functional utility and, through initial evaluations, demonstrates promise in adding to traditional training methods. SIGNIFICANCE: The system provides an environment to learn temporal bone surgery in a way similar to the experience with cadaver material where the subject is able to interact with the data without constraints (nondeterministic). Eventually, it may provide the "front end" to a large repository of various temporal bone pathologies that can be accessed through the Internet.

Algorithms↗

Temporal bone chondroblastoma: a review.

The objective of this paper was to review temporal bone chondroblastomas in regard to their presentation, radiographic findings, histopathology, and treatment. A case report of a 38-year-old man who presented with the left-sided hearing impairment and temporal swelling was reviewed. A CT scan revealed an osteolytic lobulated expansile mass. MRI depicted two cystic components with fluid-fluid level and enhanced solid mass. Immunohistochemical study of S-100 was performed using avidinbiotin-complex method. The tumor was totally removed, with eroded squamous bone and temporal muscle, via the left zygomatic-extended middle fossa approach. The pathology of the tumor showed that the tumor cell was spindle-shaped, along with multinucleated giant cells. These cells had oval to polygonal nuclei; some cells showed grooved nuclei. Intercelluar calcification and hemorrhagic components were also observed in the tumor. Tumor cells were strongly positive for S-100 protein. Temporal bone chondroblastomas are extremely rare osseous tumors with only 45 cases previously reported in the published literature. They may be confused with more common lesions seen in the temporal bone. Diagnostic radiology, including CT and/or MRI, as well as immunohistochemical staining with S-100 protein, may assist in making the diagnosis. Treatment is complete surgical excision with preservation of vital neurovascular structures.

Adult↗

Effects of gentamicin on sensorineural elements of the cochlea in human temporal bones.

PURPOSE: Gentamicin is commonly prescribed for treatment of gram-negative bacterial infections. It has, however, been known to have vestibulotoxic and ototoxic effects in humans. Previous studies were confounded by the use of other types of ototoxic drugs, higher than therapeutic doses, and prolonged time periods between gentamicin administration and death. The purpose of this study is to observe the effects of parenteral gentamicin administration on the sensorineural elements of the cochlea in which the previously described factors did not exist. MATERIALS AND METHODS: Temporal bone specimens were divided into 2 groups. Group 1 included 16 "normal" temporal bones with no history or histopathologic findings of otologic disease or ototoxic drug administration, and group 2 included 17 temporal bones that received gentamicin treatment within 6 months before death. Temporal bones were excluded from group 2 if patients had histopathologic findings or history of otologic disease and/or other ototoxic drugs. All temporal bones were examined under light microscopy. RESULTS: The percentages of intact outer hair cells in the basal turn was significantly greater in group 1 compared with group 2. There was no significant difference in hair cell number between the groups in the other turns. There was no significant difference in the number of spiral ganglion cells between groups in any turn. CONCLUSION: Although gentamicin is primarily considered to be vestibulotoxic, this study showed that gentamicin can damage sensorineural elements of the cochlea, even in younger patients. During the administration of this drug, hearing of the patient should be carefully monitored.

Adolescent↗

Clinical and surgical application of reformatted high-resolution CT of the temporal bone.

High resolution CT has played a pivotal role in temporal bone imaging since the early 1980s. Although the appearance of MR imaging technology with its superior demonstration of fluid-containing spaces of the inner ear and the posterior fossa structures, CT continues to offer distinct advantages for the evaluation of conductive hearing loss, and petrous apex lesions. With the advent of helical scanning techniques, CT is increasingly the imaging study of choice for definitive preoperative temporal bone imaging.

Bone Diseases↗

Temporal bone: three-dimensional CT. Part I. Normal anatomy, techniques, and limitations.

Three-dimensional (3D) surface renderings of the temporal bone were created from routine axial computed tomographic (CT) images in 15 subjects and in cadaver specimens. The displayed anatomy was correlated with these specimens, as well as with images from the routine study. Six sets of viewing angles were derived for optimal display of surgically important surface landmarks, such as the suprameatal triangle and supramastoid crest. The 3D CT images were found to be of excellent quality and permitted a global view of the temporal bone surface anatomy. Bone depletion artifacts ("pseudoforamina") posed a potentially serious problem in evaluating the tegmen and wall of the sigmoid sulcus, being present in eight of 20 cases. Three-dimensional CT may be a useful adjunct to routine temporal bone imaging.

Humans↗

Clinical and experimental correlations in temporal bone fracture: the facial nerve.

In this review of 50 patients with fracture of the temporal bone, 11 patients had ipsilateral facial paralysis, three of immediate and eight of delayed onset. Eight patients with complete paralysis of the facial nerve had facial nerve decompression; six of these had incomplete return of function. Only one patient with a delayed complete facial paralysis had complete return of function. The poor functional results in patients with delayed complete facial paralysis due to temporal bone fracture encourage facial nerve decompression in all stable patients with the complete facial paralysis of temporal bone fracture.

Adult↗

CT of the normal temporal bone: comparison of multi- and single-detector row CT.

PURPOSE: To evaluate multi- and single-detector row computed tomographic (CT) depiction of anatomic landmarks of temporal bone. MATERIALS AND METHODS: Institutional review board approval and written informed consent were obtained. In 50 temporal bones, transverse and coronal single-detector row CT images were compared with transverse and reformatted coronal multi-detector row CT images obtained of additional 50 temporal bones. Two radiologists evaluated images. Visibility of 50 landmarks was scored with a five-point quality rating scale. Fisher exact test, kappa statistics, and Mann-Whitney U test were used to evaluate imaging technique and landmark visibility. RESULTS: In delineating landmarks, total interobserver agreement was higher (P < .001) for transverse multi- than for single-detector row CT images. In 60% of landmarks, interobserver agreement was higher (P < .001) for transverse multi- than for single-detector row CT images. In 20% of landmarks, there was no difference, and in another 20% of landmarks, interobserver agreement was higher (P < .01) for single-detector row CT. Total interobserver agreement was higher (P < .01) for coronal multi-detector row reformations than for coronal single-detector row images. In 58% of landmarks, interobserver agreement was higher (P < .001) for coronal multi-detector row reformations than for coronal single-detector row images, while there was no difference in 8%. In 34% of landmarks, interobserver agreement was higher (P < .001) for coronal single-detector row images. Frequency of detected landmarks was higher for transverse (82%) and coronal (88%) multi-detector row images than for corresponding single-detector row images. In 72% of landmarks, transverse multi-detector row images were (P < .05) superior to corresponding transverse single-detector row images in landmark delineation. In 56% of landmarks, reformatted coronal multi-detector row images were (P < .05) superior to coronal single-detector row images in landmark delineation. CONCLUSION: Multi-detector row CT images, including reformations, better delineate temporal bone anatomy than do single-detector row CT images.

Female↗

Computed tomography of the temporal bone.

Computerized tomography (CT) is useful in otolaryngology, particularly in those patients with pathology of the posterior fossa and skull base. With the current development and improvement of CT scanners, the more detailed anatomy of the temporal bone can now be evaluated. For interpretation, detailed knowledge of the temporal bone and skull base anatomy is essential. The methodology of CT scanning of the temporal bone is presented along with a detailed description of the anatomy both in the axial and the coronal projections. A review of the current CT literature on the temporal bone is with discussion of the advantages and limitations of this diagnostic tool.

Humans↗

Meningiomas of the temporal bone.

Meningiomas should be considered in the differential diagnosis of otologic tumors arising from the middle ear and mastoid. It is generally recognized that meningiomas may invade the temporal bone via direct extension from the intracranial space (secondary). It is not generally recognized that meningiomas can develop initially in the middle ear cleft (primary). Representative cases of primary and secondary meningiomas of the temporal bone are described and clinical aspects of diagnosis surgical management are discussed. In order to assess the pathogenesis of meningiomas of the temporal bone, histological studies were done on 200 temporal bone specimens. In certain specimens, ectopic arachnoid granulations, from which primary meningiomas may originate, were identified and described, according to location. One specimen was most unusual in that it contained ectopic glial as well as arachnoidal tissue.

Brain Neoplasms↗

Squamous cell carcinoma of the temporal bone.

Squamous cell carcinoma of the temporal bone is a rare, highly malignant, aggressive disease in an extremely difficult anatomic site with a very poor prognosis. The development of an evidence base for the efficacy of its treatment has been hampered by its rarity. This article reviews current opinion based on the recent literature.

Bone Neoplasms↗

Vascular anomalies, sutures and small canals of the temporal bone on axial CT.

PURPOSE: Subtle bony structures, small canals and fine sutures cause sometimes problems in the analysis of CTs of the temporal bone. The aim of this study was: to analyze the visibility of subtle structures and to estimate the incidence of vascular anomalies. PATIENTS AND METHOD: We retrospectively analyzed axial scans of 223 high-resolution CTs of the temporal bone obtained as single slice or spiral CT with 1mm slice thickness. All CTs had clinical indications. Two experienced radiologists studied CTs regarding the visibility of the fine sutures, fissures and small canals and the occurrence of vascular anomalies. RESULTS: The following structures were seen commonly: sphenosquamosal suture (76%), arcuate artery canal (93%), vestibular aqueduct (89%), mastoid emissary vein (82%), singular canal (56%). Not so commonly were observed: tympanosquamosal suture (31%), mastoid canaliculus (28%), lateral sigmoid sinus (28%), petrotympanic fissure (24%), tympanomastoid suture (10%). Seldom we identified: the inferior tympanic canaliculus (6%), high jugular bulb (6%), anterior sigmoid sinus (5%), dehiscent internal carotid artery canal (2%), persistent petrosquamosal sinus (1%), dehiscent jugular bulb (1%). Persistent stapedial artery, aberrant internal carotid artery, dehiscent jugular bulb, high jugular bulb with diverticulum, anterior and dehiscent sigmoid sinus were detected in below 1% of the analyzed temporal bones. The frequency of asymmetry of the jugular foramen, which varied between 3% and 42%, depended on different criterions of size. CONCLUSION: A profound knowledge of normal anatomy and anomalies of the temporal bone avoids misinterpretation as pathological lesions and iatrogenic bleedings.

Adolescent↗