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Treatment of cervical dystonia (torticollis) in adults with botulinum A toxin.

Dystonias can be classified by etiology (idiopathic or symptomatic), by age of onset (childhood, adolescence or adult), and by anatomical involvement (focal, segmental or generalized). Cervical dystonia (torticollis) is one of the most common focal dystonias. We describe our experience in the treatment of 15 consecutive cervical dystonia patients by chemodenervation with botulinum A toxin (BOTOX), with significant improvement being objectively measured. Botox is accepted as a safe and efficacious modality for the treatment of cervical dystonia.

Adult↗

Biterminal tenotomy for the treatment of congenital muscular torticollis. Long-term results.

Fifty-five patients who, in a twenty-eight-year period, had been managed with a biterminal open release because of congenital muscular torticollis, were re-examined at an average of fifteen years and a minimum of five years after the operation. Forty-eight patients reported no functional or cosmetic impairment. Palpable soft-tissue strands remained in twenty-nine patients, but bending toward the untreated side was limited more than 10 degrees in only one patient. The rate of recurrence was 2 per cent. Facial asymmetry improved or resolved in more than one-half of the patients. We recommend that biterminal release be performed at the age of three to five years in all patients who do not respond to non-operative treatment.

Adolescent↗

[Arthrogryposis associated with facial scoliosis and torticollis in German Holstein calves].

In 13 German Holstein calves from two different dairy farms arthrogryposis of the front legs, facial scoliosis and torticollis were observed. Obvious environmental reasons could not be found. Chromosomal anomalies in two affected calves were not detectable. A striking feature was the high frequency of affected calves among the offspring of one natural service sire. A plausible explanation of the congenital anomalies observed is a dominantly inherited mutation restricted to germ cells.

Animals↗

[Clinical classification and the treatment of spastic torticollis].

A summary of 160 patients of spastic torticollis admitted for treatment from March 1980 to December 1990 are reported. The clinical classification of these patients is discussed. Antispasmodic operation designed by the authors was performed on them. The cure rate was 90.6%.

Adolescent↗

[Atlanto-axial rotatory fixation. Current diagnosis in torticollis].

Atlantoaxial rotatory fixation is a disorder which must be considered in persistent torticollis. The disorder occurs mainly in children and young adults. The usual etiological factors are traumas or infections of the upper respiratory tract, but the onset may also be spontaneous. The pathogenesis of the fixation is poorly understood. We describe three patients with atlantoaxial rotatory fixation and demonstrate the usefulness of computerized tomography in the diagnosis of this condition. We recommend a posterior atlantoaxial fusion if conservative treatment fails to reduce the rotatory fixation.

Adult↗

[Parapharyngeal abscess as the cause of torticollis].

The combination of parapharyngeal abscess and torticollis in an adult on account of spastic contraction of the sterno-cleido-mastoid muscle is an extremely rare condition. The present authors have recently observed a case of this type where the diagnosis was difficult to establish. CT of the neck revealed the diagnosis with no difficulty. The indication for CT at an early stage in cases of unexplained neck infections is stressed.

Abscess↗

[Injection of botulinum toxin as a new treatment of torticollis].

Thirty patients with spasmodic torticollis were injected with Botulinum A toxin into sternomastoid and posterior neck muscles. Neurophysiological investigation showed neuromuscular transmission in the sternomastoid muscle to be impaired already within the first day after injection of 50 U toxin. Signs of denervation were discernible after seven days, and of reinnervation after two weeks. As assessed by 'blind' ratings of videotapes, 78 per cent of the patients improved, as compared with the figure of 87 per cent based on clinical evaluation. When injections were repeated every third month, there was a tendency for symptomatic effects to increase with time. Side effects were mild and transient. Thus local injections of botulinum toxin would seem to be the treatment of choice in this form of dystonia.

Adult↗

Torsional Kestenbaum in congenital nystagmus with torticollis.

Surgery in idiopathic congenital nystagmus to correct an abnormal head posture is based on the shifting of neutral point. Torsional Kestenbaum has been done in cases of congenital nystagmus with torticollis, without definite localisation of null point and sustained improvement of head posture subsequent to surgery has been attributed to presumed shift of the null point. We present a 6 year-old boy with congenital horizontal nystagmus with marked head tilt towards the left shoulder. Electronystagmography showed dampening of nystagmus on left tilt. Recession/advancement of all four oblique muscles was done to shift the null point and nystagmus dampened in the primary position eliminating the head tilt. This report emphasises the significance of electronystagmography in critical decision of horizontal/torsional Kestenbaum and documentation of innervational changes following surgery and subsequent followup.

Child↗

[Treatment of spasmodic torticollis by local injections of botulinum toxin].

Injections of botulinum toxin into the main cervical muscles responsible for abnormal posture and movements in spasmodic torticollis reduced pain and attenuated dystonia for a period of 2 months on average. After several sessions 9 out of 36 patients (25 p. 100) felt they had improved by at least 50 percent, 16 (44 p.100) by 50 to 75 percent, and 6 (17 p. 100) by more than 75 percent. There were six failures.

Botulinum Toxins↗

[Long-term results of complex treatment of spasmodic torticollis].

The early and long-term results of the treatment of the patients with tonic form of spasmodic torticollis using the own method, which includes the removal of the whole involved sternocleidomastoid muscle with fascia and prolonged postoperative therapy, were studied. A method is more effective than the stereosurgical intervention, causes no neurologic complications.

Adolescent↗

Congenital muscular torticollis: a spectrum of pathology.

Congenital muscular torticollis (CMT) is a disorder characterized by a shortening of at least one of the cervical muscles and tilting of the head to the opposite side. The most commonly affected muscle is the sternocleidomastoid (SCM) muscle. An unusual case is presented here: a CMT patient with involvement of the trapezius muscle in addition to the SCM muscle who has recently been treated at North Carolina Memorial Hospital. This patient still has a slight residual deformity despite two surgical procedures, physical therapy, and splinting. A review of 41 CMT patients who presented to this institution from 1952 to the present demonstrates that the disorder is extremely variable in terms of severity of deformity and response to various types of therapy. The condition will resolve spontaneously in the majority of patients by the age of 1 year, and if the condition has not resolved by then, it is unlikely to do so without surgery. We therefore believe that surgery should be postponed until after 1 year of age. Most of the patients requiring surgery are effectively treated by division of the involved muscle in at least one area with or without lengthening of the SCM muscle. Splinting and physical therapy are recommended postoperatively. A few patients such as the unusual one with involvement of the trapezius muscle resist our most aggressive therapeutic efforts.

Female↗

[Ocular torticollis].

On account of the therapeutic consequences, it is important to determine whether a case of torticollis is oculogenic. This may involve problems as shown by the case reported here. Bielschowsky's head-inclination test is an important method of diagnosing paresis of the superior oblique muscle. In cases of paresis of this muscle, good cosmetic results can frequently be obtained by operative intervention.

Child, Preschool↗

[Torticollis spasmodicus and addiction].

From a random sample of 49 patients suffering from torticollis spasmodicus and dependence on alcohol or medicaments, 6 have been selected and are discussed with i view to findings possible mutual influences between the disorders. In particular, premorbid accentuation of personality presented itself as a potential risk factor leading to both tortocollis and alcoholism. In various cases, the patient makes use of alcohol for self-treatment of extrapyramidal-motor symptoms. But such phenomenological developments are preceded by varied constellations of conditions, that have to be taken into account in the treatment.

Adult↗

[Torticollis spasmodicus. A contribution to psychogenesis and psychotherapy].

The application of an own psychotherapeutic concept to spasmodic torticollis confirms the assumption that it represents a pantomimic expression interacting with an assumed previous organic damage. An unavowed ambivalence between wishes for support and acknowledgement and feelings of limitation and aggression-by-frustration is reflected in simultaneous spasmodic turnings towards and away with a frequent preponderance of the impulse of anxious-aggressive averting. It directed treatment renders possible stable improvements.

Adolescent↗

[The history of psychotherapy of torticollis. A historical review].

Beginning with a historical introduction the author gives an overview over the different forms of psychotherapy used for torticollis. A special reference is given to psychoanalytic concepts. The different etiological concepts of this disease imply corresponding heterogeneous forms of therapy.

Europe↗

[Experience with stereotaxic brain surgery for spasmodic torticollis].

For diagnostic and therapeutic purposes, a differentiation of torticollis spasmodicus into horizontal, rotatory, and horizontal-rotatory forms is advisable. They are supplemented by an additional retrocollis component, by further signs of torsion dystonia, and by a pure form of retrocollis. The 24 patients treated by the authors stereotactically are classified accordingly. The stereotactic exclusion of target points in the thalamus (ventro-oral nuclei, mainly V.o.i., H1, nucleus interstitialis Cajal) brought about a removal in 20.8 per cent, considerable improvement in another 20.8 per cent, a satisfactory improvement in 16.8 per cent, and a positive effect on the wryneck symptoms in 25 per cent. In 16.6 per cent of the cases no change could be achieved. Side-effects were not observed. The recommended therapeutic order ranges from peripheral interventions (injections, separating of the muscle branch of the N. accessorius) to the stereotactic operations and finally cervical rhizotomy (in rare cases).

Adult↗

[Voluntary activity of the neck muscles in patients with spastic torticollis].

The authors investigated the characteristics of motor disorders in patients with spastic torticollis. The study involved registration of volitional tensions of the neck muscles in isometric conditions, i.e., when the patient's head was rigidly fixed with regard to the body. Using a tensometric dynamometer the following three moments of force were measured: one responsible for bending the head forward or backward; the second, for bending the head to the right or left shoulder; and the third, for turning the head round the longitudinal axis. The electrical activity of the neck muscles was recorded with the help of surface electrodes. It has been established that the development of volitional efforts by the neck muscles under isometric conditions is difficult or impossible if directed to the side where the patient's forcible turn of the head is directed.

Chronic Disease↗