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At least 523 records · Page 29Linked to original sources
PubMed1997

Effects of aging on sensitivity of the pharyngeal and supraglottic areas.

As one ages, sensory discrimination in the oral cavity progressively diminishes, and dysphagia and aspiration are more likely to occur. Whether similar age-related laryngopharyngeal (LP) sensory abnormalities exist and contribute to dysphagia and aspiration is unknown. The purpose of this study was to determine if sensory discrimination in the area of the laryngopharynx innervated by the superior laryngeal nerve diminishes with increasing age. By applying a previously described device and technique that utilized endoscopically delivered air pulse stimulation of the anterior wall of the pyriform sinus, sensory discrimination can be reliably determined. LP sensory discrimination testing was performed in 80 healthy adults 23-87 years of age, with a mean age of 47 +/- 20 years. There were 60 men and 20 women. The test subjects were divided into 3 age groups, 20-40, 41-60, and > or =61. For the entire population studied, average LP sensory discrimination thresholds were 2.60 +/- 0.56 mm Hg air pulse pressure (APP). In general, there was a progressive increase in sensory discrimination threshold with each decade of life. A correlation analysis revealed that there were significant increases in pressure thresholds with advancing age (r = 0.62, P <0.0001). For subjects 20-40 years, average threshold was 2.06 +/- 0.20 mm Hg APP, for the 41-60 age group, 2.45 +/- 0.34 mm Hg APP, and for subjects > or =61, 2.97 +/- 0.78 mm Hg APP. Thresholds for the > or =61 group were significantly different from those for the 20-40 and the 41-60 groups (P <0.05). Progressive diminution in LP sensitivity with increasing age might be a contributing factor in the development of dysphagia and aspiration in the elderly.

Adult↗
PubMed1981

A malignant carcinoid tumour of the supraglottic larynx.

A rare case of carcinoid tumour of the laryngeal surface of the epiglottis in a 49-year-old woman is presented. This is the fourth report of this tumour in the world literature. The clinical features, and the light and electron microscopical appearances are discussed. The literature and the relationship to other carcinoid tumours is reviewed. Based on this and previously reported cases, recommendations are made as to management.

Carcinoid Tumor↗
PubMed1994

Neurofibroma of the supraglottic larynx in childhood.

The case of a male child with a benign neurogenic laryngeal tumour caused by von Recklinghausen's disease is presented. At the age of eight years, tracheostomy was necessary. The tumour, deforming the right half of the larynx and extending into the right half of the neck, was removed three years later. Following this procedure, decannulation was possible, and the patient has been free of laryngological complaints for six years. Attention is drawn to the fact that autosomal dominantly inherited neurofibromatosis is a generalized benign tumour with a special form. If it involves any vital structure or forms a functional obstacle, meticulous surgical removal is necessary, and this provides good prospects over a long period.

Child↗
PubMed1995

Plasma cell granuloma of the supraglottic larynx.

The occurrence of plasma cell granuloma of the larynx appears to be unusual. Review of the literature revealed only two previously reported cases. We present an additional case of plasma cell granuloma of the larynx. The diagnosis was made by histological and immunohistochemical examinations. The tumour was successfully treated by radiation therapy.

Granuloma, Plasma Cell↗