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Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

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AMENORRHOEA.

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Amenorrhea↗

Concept of true and perceived placebo effects.

We often and wrongly equate the response seen in the placebo arm of a clinical trial with the placebo effect. In order to obtain the true placebo effect, other non-specific effects can be identified by including an untreated control group in clinical trials. A review of the literature shows that most authors confuse the perceived placebo effect with the true placebo effect. The true placebo effect is highly variable, depending on several factors that are not fully understood. A distinction between the perceived and the true placebo effects would be helpful in understanding the complex phenomena involved in a placebo response.

Clinical Trials as Topic↗

Organise a clinical trial.

Organising a clinical trial is a major undertaking involving a lot of hard work before during and after the study takes place and such trials are one endeavour where there are no short cuts. Cutting corners in an effort to save time, money or effort is usually quite obvious to the assiduous journal reader who will rubbish the conclusions and tarnish one's reputation for scientific validity. By taking time to carefully think through each stage and possible eventuality of ones plans it is possible to avoid many of the stumbling blocks that interfere with the conduct of a successful trial. Consideration of the contents of this article may help to clarify matters when organising ones first clinical trial or one may wish to attend one of a growing number of courses that give instruction in many of these matters.

Clinical Trials as Topic↗