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Patterns of bladder recovery in spinal injury evaluated by serial urodynamic observations.

The results of serial urodynamic studies in spinal cord injury are presented. A number of signs which may be useful in the prediction of patients who will eventually establish spontaneous and satisfactory voiding are described. (1) Some patients with cervical high/thoracic lesions show evidence of synchrony between the external sphincter and the detrusor muscle in the phase of spinal shock. Spontaneous and efficient voiding usually occurs in this group. (2) Some patients, especially those with mild-thoracic lesions show marked dyschrony between the external sphincter/detrusor muscle in the phase of spinal shock. Early outlet surgery is indicated in this group since spontaneous and efficient voiding rarely occurs. (3) A zone of high pressure can be detected in the posterior urethra in the phase of spinal shock often within the first week after injury.

Humans↗

The effects of spinal injury on the intensity of emotional experience.

Twenty-nine subjects with spinal lesions were asked whether the intensity of their experience of eight common emotions had decreased, increased or stayed the same since injury. Analysis of their responses produced no evidence of a decline in affective tone following spinal injury.

Adult↗

Implantation of anterior sacral root stimulators combined with posterior sacral rhizotomy in spinal injury patients.

Brindley-Finetech sacral anterior root stimulators combined with posterior sacral rhizotomy were implanted in 68 males and 28 females with spinal cord lesions. In 9 patients the electrodes were implanted extradurally in the sacrum, and in 90 patients they were implanted intradurally (3 patients had a second extradural implant after a first intradural implant). Three patients died from causes unrelated to the implant. Of the 93 surviving patients, 83 used their implants for micturition and 82 were fully continent. The mean bladder capacity increased from 206 ml preoperatively to 564 ml after the operation. Three patients had a preoperative vesicorenal reflux that disappeared after surgery. In all, 51 patients used the stimulator for defecation. Erection was possible with electrical stimulation in 46 males and was used for coitus by 17 couples. Secondary deafferentation at the level of the conus was performed four times. Three patients who had a cerebrospinal fluid leak were operated on again. Two implants had to be removed because of infection. Sacral anterior root stimulation combined with sacral deafferentation is a welcome addition to the treatment of neurogenic bladder in spinal cord injury patients.

Adult↗

Fibrinolysis and spinal injury. Relationship to post-traumatic deep vein thrombosis.

Tissue plasminogen activator (t-PA) activity and antigen (t-PA:Ag) at rest and after venous occlusion (VO), were measured on admission to hospital in 9 patients with acute spinal cord injury (SCI) (group P) and in 12 patients who were immobilized due to a fracture of the cervical spine without paralysis (group C). In addition, the levels of t-PA:Ag, t-PA activity, t-PA inhibitor activity (PAI), the von Willebrand factor (vWF:Ag), F VIII:C and fibrinogen were monitored until the 10th post-traumatic day. Venous thrombosis (VT) was detected by the 125I-labelled fibrinogen test in 78% in group P and in 8% in group C. The median t-PA activity after VO was 8.6 IU/ml and 41.6 IU/ml in groups P and C, respectively (p less than 0.01). The t-PA:Ag increased similarly during VO in both groups and reached a level of 55.0 ng/ml in group P and 64.9 ng/ml in group C. The median level of PAI activity before VO was 19.2 U/ml in group P and 15.8 U/ml in group C. The trend of higher PAI values in group P than in C was more pronounced after VO (13.4 U/ml vs. 2.0 U/ml). High individual levels of PAI were found during the first 72 h of immobilization in both group P and group C. The levels of vWF:Ag and fibrinogen were significantly higher in group P than in group C on the 6th and 10th post-traumatic days and the level of FVIII:C on the 10th day.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗

Prevertebral soft tissue shadow widening--an important sign of cervical spinal injury.

Injury to the cervical spine may first be diagnosed by recognizing the increase in prevertebral soft tissue seen on a radiograph. Seven such patients are reviewed. Failure to recognize this important sign led to delay in diagnosis of the cervical spinal injury in one patient and resulted in tetraplegia. A large prevertebral swelling should be considered as an indication of a severe and unstable injury to the cervical spine and requires careful handling of the patient.

Adult↗

[Unstable spinal injuries. Guidelines for treatment].

An injury of the spine may include an injury of the neural structures in the spinal canal. This factor must always be kept in mind during care of a trauma patient until a neurologic injury has been excluded, or the spine stabilized. The classification of spine injuries and evaluation of stability are based on clinical and radiological examinations of the patient. In grade 1 unstable injuries, deformity of the spine may increase if the injury is not stabilized. In grade 2 unstable injuries, a neural involvement may occur if the injury is not stabilized. All injuries with neural involvement are by definition unstable injuries grade 3. Stabilization is indicated for all unstable injuries. In unstable injuries grade 2 and 3, a well-developed method is transpedicular osteofixation with an internal fixator which allows reduction and neutralization of the deforming forces, combined with a transpedicular bone graft to the fractured vertebra. This provides stability and allows early mobilization without immobilizing more segments than involved in the unstable area.

Adolescent↗