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Hyperkyphosis as an indicator of syringomyelia in idiopathic scoliosis: a case report.

STUDY DESIGN: A case of thoracic hyperkyphosis is reported as an atypical presentation of otherwise typical adolescent idiopathic scoliosis that showed a large syringomyelia on magnetic resonance imaging. OBJECTIVE To review atypical curve patterns that indicate the need for more intensive preoperative workup including a magnetic resonance imaging scan. SUMMARY OF BACKGROUND DATA: The literature on atypical curve patterns of adolescent "non-idiopathic" scoliosis is reviewed. No report in the literature describes patients with an idiopathic coronal plane and thoracic hyperkyphosis as an atypical feature found to have a large syringomyelia and Chiari I malformation on magnetic resonance imaging examination. METHODS: The clinical and radiographic features associated with thoracic hyperkyphosis and juvenile and adolescent scoliosis with syringomyelia are presented. RESULTS: The neurosurgical treatment of the syringomyelia subsequently led to a potentially safer spinal fusion. The patient tolerated the procedures well and at this writing has remained asymptomatic during 3 years of follow-up evaluation. CONCLUSIONS: The reported case adds to the hyperkyphosis literature category of unusual spinal deformities seen in scoliosis associated with syringomyelia and should further help to categorize adolescent idiopathic scoliosis as a diagnosis of exclusion.

Acute Disease↗

Selective screening for scoliosis.

Scoliosis screening has been practiced for nearly 50 years and has provided valuable knowledge about the prevalence and natural history of scoliosis. Early diagnosis allows for nonoperative treatment, like wearing an orthosis that has been shown to be effective by numerous outcome studies. Challenges in scoliosis screening include the low prevalence rate of clinically significant scoliosis, the inverse relationship of sensitivity and specificity in the screening process because of the poor correlation of clinical deformity and radiographic abnormality, and the inflated cost of these programs because of overreferral. Recommendations for improvement include redefinition of what actually constitutes a "significant" scoliosis for screening, diagnostic, and outcome purposes; selective screening of only immature females; the use of objective referral criteria; and re-screening patients rather than referring those who have borderline cases.

Adolescent↗

A comparison of methods for measuring spinal motion in female patients with adolescent idiopathic scoliosis.

Noninvasive surface measures of spine motion are validated in adult patients but are infrequently used in adolescent scoliosis patients. The agreement between surface and radiographic measurements of spinal motion is not known. We performed a comparative prospective analysis of 3 methods to measure spinal motion in female patients with adolescent idiopathic scoliosis (AIS) to establish normative data of spinal motion in AIS patients and evaluate the relationship between surface and radiographic measurements of spine motion. Measurements were obtained using a cloth tape measure, dual inclinometers, and a 3-dimensional electrogoniometer in 37 female patients with AIS. Radiographic parameters of the deformity were correlated with the spine motion. Differences between methods were evaluated by paired t tests. The Bland-Altman method was applied to evaluate agreement in measuring flexion. The average spinal flexion was 5.7 +/- 2.2 cm by the modified Schober method, 49 +/- 11 degrees by the dual inclinometers method, and 64 +/- 10 degrees by the 3-dimensional electrogoniometer. Spinal motion did not vary with magnitude of the scoliosis. In addition, surface measurements of spinal motion did not correlate with radiographic measurements of scoliosis flexibility. In this study, the amount of spinal motion varied, depending on the method of measurement. Surface measurements of motion cannot predict the magnitude or flexibility of the scoliosis.

Adolescent↗

Comparison of one-stage versus two-stage anteroposterior spinal fusion in pediatric patients with cerebral palsy and neuromuscular scoliosis.

STUDY DESIGN: A retrospective study was performed including 45 pediatric patients with spastic quadriplegic cerebral palsy and neuromuscular scoliosis who underwent anteroposterior spinal fusion. OBJECTIVES: To evaluate the outcomes and complications of one-stage and two-stage combined anteroposterior spine fusion and to document which procedure is more efficacious and provides better results. SUMMARY OF BACKGROUND DATA: Circumferential spinal arthrodesis has been proven to achieve better scoliotic curve correction, decreasing significantly the risk of pseudarthrosis and progression of the deformity. There have been a few studies comparing same-day versus staged anteroposterior spinal surgery in mixed populations with neuromuscular scoliosis, but not in an isolated group of pediatric patients with spastic cerebral palsy. METHODS: The medical records and radiographs of all patients were reviewed, and the results were statistically analyzed. The complications were divided into medical, subcategorized into major and minor, and technical. RESULTS: There was no statistically significant difference (P > 0.05) between one-stage (Group 1) and two-stage (Group 2) patients, considering age at surgery, preoperative scoliosis angle, pelvic obliquity, kyphosis angle, lordosis angle, levels of anterior release, percentage of scoliosis correction, radiographic follow-up, hospitalization time, and intensive care unit stay. Sequentially performed spinal procedures (Group 1) were associated with increased intraoperative blood loss, prolonged operative time, and a considerably higher incidence of medical and technical complications, including two perioperative deaths. CONCLUSION: Two-stage anteroposterior spinal fusion provides safer and more consistent results with several advantages over the single-stage procedure in the management of patients with cerebral palsy and neuromuscular scoliosis.

Adolescent↗

Anterior endoscopic discectomy and fusion for adolescent idiopathic scoliosis.

STUDY DESIGN: A review of adolescent patients with idiopathic scoliosis undergoing endoscopic release and spinal fusion. OBJECTIVE: To describe the indications, techniques, results, and complications of thoracic anterior endoscopic scoliosis surgery. SUMMARY OF BACKGROUND DATA: Anterior endoscopic treatment of thoracic adolescent idiopathic scoliosis has become an alternative method of surgical treatment. METHODS: Twenty-one patients with adolescent idiopathic scoliosis have undergone a thoracic anterior endoscopic release and fusion followed by posterior instrumentation and fusion. Indications for the endoscopic fusion were large curve magnitude, skeletal immaturity, and/or thoracic hyperkyphosis. Eleven patients have undergone anterior endoscopic instrumentation and fusion for thoracic scoliosis curves between 45 degrees and 70 degrees, using a single screw/single rod construct and autogenous rib bone graft. RESULTS: Results from the anterior endoscopic release and fusion procedures followed by a posterior instrumentation and fusion had an average preoperative curve of 82 degrees (range, 41 degrees -125 degrees ), with postoperative correction to 28 degrees (range, 5 degrees -60 degrees ) showing 70% correction. For patients undergoing an anterior endoscopic instrumentation and fusion, the average preoperative Cobb measurement of 53 degrees (range, 44 degrees -62 degrees ) was corrected to an average 26 degrees (range, 18 degrees -38 degrees ) for an average correction rate of 51%. One patient undergoing an anterior endoscopic release was converted to an open procedure for end plate bony bleeding without sequelae. One patient with an anterior endoscopic instrumentation and fusion had revision anterior surgery for a distal set screw dislodgment and subsequent posterior instrumentation and fusion for pseudarthrosis. CONCLUSIONS: The use of both anterior endoscopic release and fusion combined with either anterior instrumentation or separate posterior instrumentation and fusion continues to evolve. Surgeons treating patients with these techniques must understand that there are specific indications for them and many technique options available to optimize surgical results.

Adolescent↗

Anterior single rod instrumentation for thoracolumbar adolescent idiopathic scoliosis with and without the use of structural interbody support.

STUDY DESIGN: A radiographic and clinical outcomes analysis of 41 patients treated for thoracolumbar adolescent idiopathic scoliosis utilizing a single anterior rigid rod construct. OBJECTIVES: To evaluate the necessity of structural interbody support to improve primary curve correction and preserve or augment lordosis when used in conjunction with a single anterior rigid rod construct, to identify parameters that predict horizontalization of the lowest instrumented vertebra, adjacent disc angulation, and distal uninstrumented vertebrae, and to assess patient satisfaction following surgery. BACKGROUND DATA: Instrumentation-induced kyphosis has been a concern with nonrigid anterior systems used in the past for the treatment of scoliosis. Interbody structural support has been recommended to maintain appropriate sagittal profile when anterior systems are utilized. It has also been suggested that the use of structural interbody support creates a fulcrum to increase curve correction when compression is applied to the convexity of the deformity. However, the necessity of interbody structural support when used in conjunction with a rigid anterior system has not been previously evaluated in patients with adolescent idiopathic scoliosis. MATERIALS AND METHODS: Forty-one patients mean age 15.9 years (range 12.1-18.6 years) with thoracolumbar adolescent idiopathic scoliosis underwent anterior spinal fusion using a single 6.0 to 6.5 mm solid rod construct between June 1995 and August 1999 performed by the senior author (T.G.L.). Four additional patients with thoracolumbar curves with similar anterior instrumentation over the same time period were lost to follow-up or had incomplete records and were not included in the study. Structural interbody support was used in 21 patients and packed morselized autograft alone was used in 20 patients. The patients in the group with packed morselized bone alone generally underwent surgery earlier in the series before the author began using structural interbody support on a regular basis. Each patient had a minimum follow-up of 3 years. Preoperative, initial, and most recent (>3 years) follow-up radiographs were reviewed to determine in each group Cobb angle measurements, flexibility of primary, secondary, and fractional curves, apical and end vertebral translation, lowest instrumented vertebral and caudal disc angulation, global coronal and sagittal balance, and sagittal Cobb measurements in both instrumented levels as well as lumbar lordosis (T12-S1). In addition, the SRS outcomes instrument was completed by 38 of 41 patients. RESULTS: The mean preoperative primary curve in patients with structural support was 47 degrees (Group II) and 45 degrees in patients without structural support (Group I). Mean curve correction was to 13 degrees in Groups I and II. One patient in Group II became slightly more unbalanced at final follow-up; otherwise all were improved after surgery. Sagittal measurements over instrumented segments as well as total lumbar lordosis (T12-S1) was maintained between preoperative and final postoperative values in both groups. Similarly, in both groups, when horizontalization of the distal end instrumented vertebra was achieved on the preoperative reverse side-bending radiograph, more normal relationships were achieved between instrumented and distal noninstrumented segments (adjacent disc angulation and fractional lumbar curve) at final follow-up (P <or= 0.01). Patients in both groups were equally pleased with their clinical outcomes based on the SRS outcomes instrument. CONCLUSIONS: The use of interbody structural support does not appear to be necessary to maintain an appropriate sagittal profile or to maximize coronal curve correction when a rigid rod construct with packed morselized bone is used for the treatment of thoracolumbar adolescent idiopathic scoliosis. Parameters predicting horizontalization of the lower instrumented vertebra and uninstrumented segments below the construct were identified, which, if achieved, should predict an optimal long-term outcome. Clinical outcomes were very good in both groups.

Adolescent↗

The Lenke classification of adolescent idiopathic scoliosis: how it organizes curve patterns as a template to perform selective fusions of the spine.

STUDY DESIGN: Retrospective radiographic review. OBJECTIVES: To analyze how the Lenke classification of adolescent idiopathic scoliosis provides a template of specific curve patterns that may be appropriate to perform selective fusion of the spine. METHODS: A new triad classification system of adolescent idiopathic scoliosis has been developed. It consists of a curve type, a lumbar spine modifier (A, B, C), and a sagittal thoracic modifier (-, N, +). A selective fusion is termed when both the thoracic and thoracolumbar/lumbar curves deviate completely from the midline, but only the major curve (largest Cobb measurement) is fused, leaving the minor curve unfused and mobile. In this manner, selective thoracic fusions of the spine are potentially indicated for major main thoracic/minor lumbar curves (Types 1C and potentially 2C and 3C patterns) when the lumbar apex deviates off the center sacral vertical line. Conversely, selective thoracolumbar/lumbar fusions may be indicated for major thoracolumbar/lumbar-minor main thoracic curves, when the thoracic apex lies off the C7 plumbline (Type 5C and potentially 6C patterns). Importantly, additional analysis of ratios of structural characteristics between the main thoracic and thoracolumbar/lumbar curves are necessary to predict when a successful selective main thoracic or thoracolumbar/lumbar fusion will be feasible. Lastly, the clinical appearance of the patient's truncal alignment is essential to confirm the aspirations of performing a selective spinal fusion. RESULTS: Successful selective thoracic fusion of 1C (n = 36) and 2C (n = 8) curves have been performed in 44 consecutive patients with adolescent idiopathic scoliosis. The average thoracic curve was 61 degrees before surgery and 39 degrees at final follow-up. The average preoperative lumbar curve was 48 degrees, decreasing to 32 degrees postoperatively. A group of 21 consecutive patients with Type 5C or 6C major thoracolumbar/lumbar-minor main thoracic curves underwent a selective thoracolumbar/lumbar fusion. The average preoperative thoracolumbar/lumbar curve was 56 degrees corrected to 22 degrees at the 2-year follow-up. The average minor main thoracic curve preoperative was 38 degrees, with spontaneous correction to 28 degrees at 2 years postoperative. DISCUSSION: Selective thoracic or thoracolumbar/lumbar fusion can be successfully performed in a variety of adolescent idiopathic scoliosis curve patterns. Careful attention to the preoperative Lenke curve classification, analysis of structural characteristics between the planned instrumented and noninstrumented regions of the spine, as well as a documented clinical examination that confirms the planned instrumented and fused regions of the spine to be the most clinically prominent are essential features to determine before surgery. No patients undergoing selective thoracic fusion have required extension of the fusion to the lumbar spine, whereas one patient with a selective thoracolumbar fusion required extension of the fusion up to include the thoracic spine due to continued thoracic progression with growth. CONCLUSIONS: Selective thoracic or thoracolumbar/lumbar fusions of the major curve can be successfully performed even when the minor curve completely deviates from the midline, based on the Lenke classification system, the analysis of structural criteria between the planned fused and unfused regions of the spine, and the clinical examination of the patient. Selective fusions, when successfully performed, will optimize mobile segments of the spine in patients with adolescent idiopathic scoliosis.

Adolescent↗

An innovative technique of vertebral body stapling for the treatment of patients with adolescent idiopathic scoliosis: a feasibility, safety, and utility study.

STUDY DESIGN: Retrospective review. OBJECTIVES: To report the feasibility, safety, and utility of vertebral body stapling without fusion as an alternative treatment for adolescent idiopathic scoliosis. SUMMARY OF BACKGROUND DATA: The success rate of brace treatment of adolescent idiopathic scoliosis ranges from 50% to 82%. However, poor self-image and brace compliance are issues for the patient. An alternative method of treatment such as a motion-preserving vertebral body stapling to provide curve stability would be desirable. METHODS: We retrospectively reviewed 21 patients (27 curves) with adolescent idiopathic scoliosis treated with vertebral body stapling. Patients were immature as defined by Risser sign or=6 degrees or beyond 50 degrees was considered a failure of treatment. Of these 10 patients, 6 (60%) remained stable or improved and 4 (40%) progressed. One of 10 (10%) in the stapling group had progressed beyond 50 degrees and went on to fusion. Six patients required stapling of a second curve, three as part of the primary surgery, and three as a second stage, because a second untreated curve progressed. The results need to be considered with caution, as the follow-up is still short. CONCLUSIONS: The data demonstrate that vertebral body stapling for the treatment of scoliosis in the adolescent was feasible and safe in this group of 21 patients. In the short-term, stapling appears to have utility in stabilizing curves of progressive adolescent idiopathic scoliosis.

Adolescent↗

Do you see what I see? Looking at scoliosis surgical outcomes through orthopedists' eyes.

STUDY DESIGN: A prospective study evaluated orthopedists' ratings of preoperative and postoperative cosmesis in adolescents undergoing posterior or anterior spinal fusion for idiopathic scoliosis. Measures evaluated how orthopedists rated outcome in relation to patient satisfaction with the surgical result. SUMMARY OF BACKGROUND DATA: The reliability of physician-derived data as a method for evaluating scoliosis surgical outcomes has not been sufficiently explored and has not been related to patient satisfaction ratings with the postoperative result. OBJECTIVES: The purpose of this study was to determine 1) the intrarater and interrater reliability estimates of orthopedists' ratings of scoliosis surgical outcomes and 2) the association between orthopedists' ratings and patient satisfaction ratings with the postoperative cosmesis. METHODS: Six orthopedists independently rated preoperative and postoperative color slides for cosmetic deformity in 41 patients with adolescent idiopathic scoliosis. Patients rated their satisfaction with the postoperative cosmesis 5 to 11 months after surgery. RESULTS: The intrarater and interrater reliabilities of orthopedists' assessments of scoliosis surgical outcomes ranged from fair to poor. Orthopedists' assessments of postoperative shoulder asymmetry significantly correlated with patient satisfaction ratings of cosmetic appearance following surgical correction of severe curves. Patient satisfaction ratings were unrelated to orthopedists' ratings of scar appearance, cosmetic deformity, and preoperative to postoperative cosmetic change. CONCLUSIONS: Intrarater and interrater reliability estimates were unacceptably low when evaluating spinal surgical outcomes in these 41 patients. Overall, orthopedists' ratings were not significantly correlated with patient satisfaction ratings of the postoperative result.

Adolescent↗

The course of sagittal plane abnormality in the patients with congenital scoliosis managed with convex growth arrest.

SUMMARY OF BACKGROUND DATA: Patient age; localization, length, and magnitude of the curve; and sagittal plane alignment are reported to be the major determinants in the selection of patients for convex growth arrest. Although the existence of sagittal plane abnormality (kyphosis or lordosis) is accepted as a contraindication for convex growth arrest, this issue has not been discussed in detail. OBJECTIVES: The purposes of this study are to investigate the effect of sagittal plane abnormality on the control of coronal plane deformity and to evaluate the course of sagittal plane abnormality of the patients with congenital scoliosis who were satisfactorily managed with convex growth arrest. STUDY DESIGN: Retrospective analysis. METHODS: Inclusion criteria are: 1) a diagnosis of congenital scoliosis in a patient younger than 6 years of age, 2) treatment with convex growth arrest, 3) follow up for more than 2 years, 4) stabilized or improved coronal plane deformity, and 5) abnormal sagittal plane alignment within the scoliotic segment before surgery. The patients were evaluated with anteroposterior and lateral radiographs, and segmental measurements were compared according to the normal of their corresponding age. RESULTS: A total of 38 patients with congenital scoliosis treated with convex growth arrest were reviewed. Among 13 patients with segmental sagittal plane deformity, 2 were excluded because of insufficient control of the scoliosis. Eleven patients (8 girls, 3 boys) with a mean age of 35 months (range 6-72 months) and mean follow-up of 40 months (range 24-76 months) fulfilled these criteria. The coronal plane deformities were 58 degrees (range 36 degrees-105 degrees) before surgery and 52 degrees (13 degrees-107 degrees) at the final follow-up. While six of the curves improved, the remaining ones stabilized. Sagittal segmental alignments within the scoliotic segments were hyperkyphotic in 9 patients and hypokyphotic in 1 and lordotic in 1. At the end of the follow-up, sagittal Cobb angle of the abnormal segments remained stable in 7 patients and deteriorated in 4. None of the 4 patients required any reconstructive spine procedure for kyphosis during follow-up. CONCLUSION: Sagittal segmental abnormality does not have a negative effect on the control of scoliosis in the majority of the patients (11 of 13). If the coronal curve stabilizes or improves, then sagittal segmental abnormality could also be stabilized (in 7 of 11 patients).

Child, Preschool↗

Clotting parameters and thromboelastography in children with neuromuscular and idiopathic scoliosis undergoing posterior spinal fusion.

STUDY DESIGN: An unblinded comparison of laboratory values between patients with idiopathic and neuromuscular scoliosis. OBJECTIVES: To compare standard tests of coagulation and thromboelastography (TEG) parameters between two groups of patients undergoing posterior spinal fusion (PSF). SUMMARY OF BACKGROUND DATA: Children with neuromuscular scoliosis such as cerebral palsy have more intraoperative blood loss than children with idiopathic scoliosis during PSF. Various reasons suggested for this include nutritional deficiencies, altered tissue integrity, hepatic dysfunction, and use of antiepileptic medications that can cause poor hemostasis and altered coagulation. We have observed alterations in coagulation factor levels in patients with cerebral palsy due to spastic quadriplegia with moderate blood volume loss (25% estimated blood volume). METHODS: In a prospective analysis, we compared standard tests of coagulation (prothrombin time [PT], partial thromboplastin time [PTT], platelet count, fibrinogen levels) and TEG at baseline and at a blood loss of 15% estimated blood volume in patients with idiopathic scoliosis and cerebral palsy undergoing PSF. RESULTS: There were no differences between the groups in terms of gender distribution and age. There was a significant difference between the baseline PT and PTT values, although both groups were within laboratory norms. After 15% blood volume loss, there were differences seen in the PT, PTT, maximum amplitude on the TEG, ionized calcium, and serum magnesium levels (P < 0.05). CONCLUSIONS: Children with cerebral palsy undergoing PSF have increased bleeding that starts earlier in the procedure than it does for patients with idiopathic scoliosis undergoing PSF. We found that, even though children with spastic quadriplegia had baseline PT and PTT values within normal limits, they were significantly different when compared with normal patients.

Adolescent↗

Fusionless scoliosis correction using a shape memory alloy staple in the anterior thoracic spine of the immature goat.

STUDY DESIGN: Experimental scoliosis was created in goats and then treated using anterior thoracic stapling. OBJECTIVE: To correct, without fusion, a progressive idiopathic-type scoliotic deformity in an immature goat model using a shape memory alloy staple. SUMMARY OF BACKGROUND DATA: Fusionless scoliosis treatment techniques, using minimally invasive approaches to the anterior thoracic spine, provide theoretical advantages over currently available forms of treatment. METHODS: Experimental scoliosis was created in 40 goats using a posterior asymmetric tether with convex rib resection and concave rib tethering for a period of up to 15 weeks. Twenty-seven goats with progressive deformities were used for subsequent study and randomized into 4 treatment groups: group I, anterior thoracic stapling with removal of the posterior tether; group II, removal of the posterior tether only; group III, anterior thoracic stapling with persistent posterior tethering; and group IV, persistent posterior tethering with no treatment. The treatment period lasted an additional 6 to 14 weeks. Staple backout was graded radiographically. After killing the goats, histology and disc biochemistry analyses were conducted. RESULTS: The goats in group I corrected from an initial 57 degrees of curvature to 43 degrees over the duration of the treatment period. Group II goats, which served as a control for group I, corrected from 67 degrees to 60 degrees during the treatment period. Group III goats demonstrated a modest correction from 65 degrees to 63 degrees with the stapling procedure, whereas group IV goats (controls for group III) progressed from 55 degrees to 67 degrees with a persistent posterior tether during the treatment period. The difference between the correction in group III and progression in group IV was statistically significant (P = 0.002). Complications were limited to partial staple backout in 27% of 56 staples. CONCLUSIONS: The results of this study support the efficacy of an anterior thoracic staple in correcting moderately severe scoliosis and halting the progression of more malignant scoliosis without fusion in a goat model.

Alloys↗

Postoperative analgesia following surgical correction for adolescent idiopathic scoliosis: a comparison of continuous epidural analgesia and patient-controlled analgesia.

STUDY DESIGN: A retrospective comparison of postoperative continuous epidural analgesia and patient-controlled analgesia following surgical treatment for adolescent idiopathic scoliosis. OBJECTIVES: To compare the safety and efficacy of continuous epidural analgesia and patient-controlled analgesia following adolescent idiopathic scoliosis surgery. SUMMARY OF BACKGROUND DATA: The most commonly used pain management techniques are continuous epidural analgesia and patient-controlled analgesia. However, no large published reports compare them following adolescent idiopathic scoliosis surgery. METHODS: A review was performed from 1990 to 2001 of patients undergoing primary surgery for adolescent idiopathic scoliosis. Visual analog scale scores were recorded postoperatively at multiple time periods. Adverse effects related to each pain management technique were noted. RESULTS: The average of all pain scores (1.3 vs. 1.9) (P < 0.0001) and scores at 2, 4, 6, 8, 12, 24, 36, and 48 hours (p < 0.001) was significantly better in the continuous epidural analgesia group when compared to the patient-controlled analgesia group. The range of pain scores (2.3 vs. 2.7) (P < 0.05) and the average maximum score was less in the continuous epidural analgesia group (2.6 vs. 3.2) (P < 0.05). The need to temporarily stop and then restart the pain management (12.3% vs. 7.0%) (P = 0.04) and premature permanent discontinuation (13.1% vs. 0.0%) (P < 0.001) was greater in the continuous epidural analgesia group than the patient-controlled analgesia group. No neurologic injuries occurred. CONCLUSIONS: Although both continuous epidural analgesia and patient-controlled analgesia provide effective pain control following surgery for adolescent idiopathic scoliosis, patients with continuous epidural analgesia had significantly better pain scores for all time periods, less fluctuations in pain, and lower maximum pain levels during the postoperative period.

Adolescent↗

Assessment of bone quantity and distribution in adult lumbar scoliosis: new dual-energy x-ray absorptiometry methodology and analysis.

STUDY DESIGN: In this study, we elucidated the bone quantity and distribution in lumbar spines of a group of 176 postmenopausal women (average age 72 years) with scoliosis. SUMMARY OF BACKGROUND DATA: Adolescent idiopathic scoliosis is associated with a low bone mineral density, but the bone mineral density in adult lumbar scoliosis has not been well-characterized. METHODS: Dual-energy x-ray absorptiometry analysis of the femoral neck and lumbar spines of 176 postmenopausal women were used to assess the bone mineral density and bone mineral content at both anatomic sites. Subsegmental analysis was used to determine the bone distribution within the lumbar vertebrae. RESULTS: The lumbar spine bone mass was greater than the femoral neck as evidenced by the average lumbar spine and femoral neck T-scores, -0.493 and -1.81, and Z-scores, 1.70 and 0.12, respectively. There was also a significant correlation between the lumbar spine bone mineral density and femoral neck bone mineral density (r2 = 0.24, P < 0.0001). Individual analysis of 655 vertebrae after bisection and trisection showed that the bone mineral density of the concave side was 15% to 20% higher than the convex, and the difference between the 2 sides was at least as great for patients with low femoral neck bone mineral density as those with high femoral neck bone mineral density. CONCLUSIONS: The quantity and distribution of bone in adult scoliosis is markedly different from adolescent scoliosis. The lumbar spine bone mass is much greater than the femoral neck, and the concave side bone mass is greater than the convex. Finally, subsegmental vertebral dual-energy x-ray absorptiometry analysis may have wider applications in research and clinical settings.

Absorptiometry, Photon↗

Pseudarthrosis in primary fusions for adult idiopathic scoliosis: incidence, risk factors, and outcome analysis.

STUDY DESIGN: A retrospective study. OBJECTIVE: To analyze the incidence, characteristics, risk factors, and Scoliosis Research Society Instrument-24 (SRS-24) outcome scores of pseudarthrosis in adult idiopathic scoliosis primary fusions. SUMMARY OF BACKGROUND DATA: The healing of spinal fusion is complex and difficult to study in a clinical setting. There are no detailed reports on pseudarthrosis in primary fusion for adult idiopathic scoliosis since the introduction of "modern" segmental fixation techniques. METHODS: A retrospective chart and radiographic review of 96 patients (average age 42.2 years; range 18.2-62.9 years) with adult idiopathic scoliosis undergoing first time (primary) spinal instrumentation and fusion with a minimum 2-year follow-up (average 5.9 years; range 2-16.8 years) treated at a single institution between 1985 and 2001 were analyzed. RESULTS: Sixteen patients had pseudarthroses (17%). Fifty-nine percent of the pseudarthroses occurred between T9 and L1, and 81% presented with multiple levels involved (2-6 levels). The site of crosslinks or dominoes correlated with pseudarthrosis site in 69%. Pseudarthroses were detected radiologically at 32.4 months (range 12-67 months) postoperatively. Patient age at surgery more than 55 years significantly correlated with pseudarthrosis (P = 0.007). The number of fused levels more than 12 vertebrae is also significantly correlated with pseudarthrosis (P = 0.03). Smoking history and comorbidity did not increase the pseudarthrosis rate (P = 0.71 and 0.19, respectively). A larger preoperative Cobb angle (> or =70 degrees) and a greater thoracic kyphosis (T5-T12 >40 degrees) did not correlate with a higher pseudarthrosis rate (P = 0.76 and 0.73, respectively). Thoracolumbar kyphosis (T10-L2 > or =20 degrees) correlated with a significantly higher pseudarthrosis rate (P < 0.0001). Preoperative global sagittal and coronal imbalance did not increase the pseudarthrosis rate (P = 0.45 and 0.62, respectively). Patients with pseudarthrosis had lower SRS-24 scores than those without (P = 0.01). CONCLUSION.: The incidence of pseudarthrosis following adult idiopathic scoliosis primary fusion was 17%. The pseudarthrosis was most likely to occur at the thoracolumbar junction. Older patients (>55 years), longer fusion (>12 vertebrae), and those with thoracolumbar kyphosis (> or =20 degrees) demonstrated increased risk for pseudarthrosis. Patients' outcomes as measured by the SRS-24 were "negatively" affected by the pseudarthrosis.

Adolescent↗

Psychologic management of brace therapy for patients with idiopathic scoliosis.

STUDY DESIGN: A trial of brace therapy modified by a measured personality pattern of patients with idiopathic scoliosis was performed. OBJECTIVE: To evaluate the effectiveness of performing personality tests for patients with idiopathic scoliosis who undergo brace therapy. SUMMARY OF BACKGROUND DATA: Brace therapy has often been used for the treatment of scoliosis. However, emotional distress can result from this therapy. Few attempts have been made to reduce such stress. METHODS: A test using the Maudsley Personality Inventory was performed on 145 adolescent females with idiopathic scoliosis, treated with brace therapy alone, before the start of brace therapy and 1 month after the start of brace therapy. On the basis of test results, the patients were rated as normal type and four abnormal types. Brace therapy was continued considering the personality pattern of patients. For all patients, changes in psychologic test results, compliance with braces wearing instructions, and correction of scoliosis were analyzed. RESULT: Of the 134 patients rated as normal before the start of therapy, 108 patients were rated as abnormal pattern when tested 1 month after the start of therapy. After performing autogenic training for patients with E-N+ and E-N- personalities, and giving advice to school teachers to decrease the emotional stress for patients with E+N+ personality, 47 patients were finally rated as abnormal pattern. In total, 12 (8%) of the 145 patients dropped out. In dropouts, the average pretreatment deformity of 29 degrees (range: 21 degrees -37 degrees ) had increased to an average of 37 degrees (range, 31 degrees -48 degrees ). CONCLUSION: Psychologic tests may be useful and provide a means of modifying brace therapy tailored to the psychologic conditions of individual patients.

Adolescent↗

Perioperative changes in pulmonary function after anterior scoliosis instrumentation: thoracoscopic versus open approaches.

STUDY DESIGN: A prospective evaluation of pulmonary function in patients with adolescent idiopathic scoliosis undergoing surgical correction. OBJECTIVE: To determine if a minimally invasive thoracoscopic approach had less postoperative pulmonary function impairment compared to open anterior instrumentation for idiopathic scoliosis. SUMMARY OF BACKGROUND DATA: Prior studies suggest that open anterior scoliosis surgery causes an initial decrease in pulmonary function that resolves by 2 years after surgery. However, the effect of thoracoscopic instrumented scoliosis correction on pulmonary function is unknown. METHODS: Fifty-four patients with AIS undergoing anterior spinal instrumentation and fusion at the authors' institutions were evaluated with pulmonary function tests assessing forced vital capacity (FVC) and forced expiratory volume in one second (FEV1). Patients were evaluated before surgery,as well as 3 months and 1 year after surgery. There were 2 groups of patients: in one group, a thoracoscopic technique was used to visualize and instrument the anterior spine (n = 31); and in the other, an open single or double thoracotomy was used (n = 23). RESULTS: Three months after surgery, the thoracoscopic group had a significantly smaller decline in FVC than the thoracotomy group; at 1 year after surgery, the thoracoscopic group had recovered, while FVC remained reduced in the open group. The decline in FEV1 from before surgery to 3 months after surgery was similar between groups; however, by 1 year after surgery, the thoracoscopic group had more recovery of pulmonary flow than the thoracotomy group. CONCLUSIONS: The thoracoscopic approach causes a smaller decline in pulmonary function 3 months and 1 year after surgery as compared to the more invasive technique of open thoracotomy for anterior spinal instrumentation for correction of adolescent idiopathic scoliosis.

Adolescent↗

Idiopathic scoliosis in Singapore schoolchildren: a prevalence study 15 years into the screening program.

STUDY DESIGN: A point prevalence survey of 72,699 schoolchildren in four age groups was performed. OBJECTIVES: To determine the prevalence rates of idiopathic scoliosis and to compare with a previous prevalence study done 15 years earlier. SUMMARY OF BACKGROUND DATA: Prevalence rates for idiopathic scoliosis of 5 degrees or more in schoolchildren were established in a study performed in 1982. There have been no previous data on prevalence rate changes over time. METHODS: A total of 35,558 boys and 37,141 girls from randomly selected schools were screened for scoliosis. Those with scoliometer readings of more than 5 degrees underwent radiographic evaluation. Prevalence rates were calculated for scoliosis at a predefined Cobb angle of 10 degrees and 5 degrees , the latter for comparison with the previous prevalence study. Curve type and distribution, pubertal status, and symptoms were correlated with the prevalence data. RESULTS: Prevalence rates were 0.05% for girls and 0.02% for boys at 6 to 7 years of age, 0.24% for girls and 0.15% for boys at 9 to 10 years of age, 1.37% for girls and 0.21% for boys at 11 to 12 years of age, and 2.22% and 0.66%, respectively, for girls and boys at 13 to 14 years of age. The ratio of girls to boys increased from 1.6 at 9 to 10 years of age to 6.4 at 11 to 12 years of age. Thoracolumbar curves were the most common (40.1%), followed by thoracic curves (33.3%), double/triple curves (18.7%), and lumbar curves (7.9%). Older children had greater proportions of larger curves. Compared with the previous prevalence study in 1982, there was a significant increase in the prevalence rate in girls 11 to 12 years of age. Screening of 11- to 12- and 13- to 14-year-old girls detected curves in the range suitable for bracing, with nearly 96% and 32% of the age groups, respectively, still amenarche or within a year of menarche, and 57% and 34% of the age groups, respectively, having low Risser grades of 0, 1, and 2. CONCLUSIONS: The overall prevalence rate of idiopathic scoliosis in our school population in 1997 was 0.93% in girls and 0.25% in boys. The prevalence rates were low at 6 to 7 and 9 to 10 years of age but increased rapidly to 1.37% and 2.22% for girls at 11 to 12 and 13 to 14 years of age, respectively. The prevalence rate increased significantly in 11- to 12-year-old girls over a 15-year period from 1982 to 1997. Screening of 11- to 12- and 13- to 14-year-old girls identified a significant number who could benefit from brace treatment.

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