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Two new cases of XYY chromosome complement: and a review of the literature.

Two cases with XYY chromosome complement are presented and compared with 153 cases described in the literature. Some patients with abnormalities of personality development and manifest psychopathology may have sex chromosome abnormalities and should be studied further for the interaction of genetic and environmental factors in personality development. In particular, tall, schizoid impulsive men with a history of criminality, arson or sexual offences should be screened for this particular genetic configuration. Because of the biased manner by which most of the cases are found, it is not yet known whether an XYY genotype results in a characteristic phenotype. What is needed is a genetic study of a normal population and a prospective study of newborns with various genotypes which would, unfortunately, create complex research and ethical problems.

Adolescent↗

[Severe abnormal development of the personality that can be regarded as pathological--initial results of a catamnestic study].

Proceding from the definition of "severely abnormal development of the personality that can be regarded as pathological" (SAPEK) as defined by Lange in collaboration with the 5th Penal Senate of the supreme court and with reference to the different forms of maldevelopment as categorized by Szewczyk, the author uses his own catamnestic studie to discuss the bounds and frequencies of such abnormal personality developments and criteria for the "severity of the illness" in the sense of Section 16, paragraph 1 (2nd option) of the Code of Criminal Law. In view of their importance, dissocial and psychosexual maldevelopment is dealt with in greater detail.

Adolescent↗

Joining group psychotherapy: developmental considerations.

This article examines the experience of new members joining an ongoing psychotherapy group. The group's stage of development and the new member's personality development are suggested to be important variables in this significant event. The experience of joining is found to share some things in common with the beginning phase of group for the group as a whole, but also noted are some unique elements. The process of joining is viewed as a highly anxious event for the new member, with antecedents in the individual's life experience. The new member is compromised by not knowing the group members, nor their shared history, norms, and dynamics. Concurrently, the group may experience a range of fears, wishes, and anxieties about the new member. Developmental considerations for the new member and the stage of group help to inform intervention strategies.

Adaptation, Psychological↗

Drug tourism or spiritual healing? Ayahuasca seekers in Amazonia.

This research addresses the question of whether Westerners who seek traditional spiritual medicine known as ayahuasca can be best characterized as "drug tourists" or as people pursuing spiritual and therapeutic opportunities. Participants in an ayahuasca retreat in Amazonia were interviewed regarding their motivations for participation and the benefits they felt that they received. These findings from the interviews were organized to reveal common motivations and benefits. Contrary to the characterization as "drug tourists", the principal motivations can be characterized as: seeking spiritual relations and personal spiritual development; emotional healing; and the development of personal self-awareness, including contact with a sacred nature, God, spirits and plant and natural energies produced by the ayahuasca. The motivation and perceived benefits both point to transpersonal concerns, with the principal perceived benefits involving increased self awareness, insights and access to deeper levels of the self that enhanced personal development and the higher self, providing personal direction in life.

Adult↗

Personality changes in the aged. A longitudinal study with the MNT-scale.

The three personality dimensions validity, solidity and stability according to Sjöbring were measured by means of the MNT scales in representative samples of 70-year-old men and women in Gothenburg, Sweden. They were followed up when 75 and 79. A longitudinal study was performed with regard to changes in means, standard deviations and sex differences. The means at 70 of the surviving subjects were compared with those of subjects who had died before the age of 79. The personality dimensions were, on the whole, unchanged between 70 and 79 except for a small increase in stability in men, implying a decrease in personal involvement, and a small decrease in validity in women implying lower levels of mental energy. There was also a decrease in solidity in men between 75 and 79 implying an increased tendency to dissociation. Variability and sex differences did not change. Men with low validity at 70 had an increased mortality. Cross-sectional studies would have given misleading results of the personality development in these age groups.

Aged↗

A new perspective on intervention in heavy, chronic drug use.

No single intervention strategy can solve all problems of drug abuse. Large-scale methods do not contribute to understanding or solving the problems of individual persons. Research on individuals shows that each major drug of abuse produces a distinctive ego state. Heavy, chronic users choose drugs which generate states that provide the illusion of solving personal problems, the origins of which are traceable to early personal development. A previously described theory attributed these problems to difficulties in Ego development. It is also necessary, however, to account for numinous factors. This is accomplished by postulating the existence of the Self, an unconscious counterpart of the Ego. Successful personal development carries both Ego and Self along a spiraling course through the major crises of individuation. The relationship of Self and Ego is expressed by life themes. These derive from myths that live themselves out as autonomous complexes in an individual's life. Therapists who treat individuals must work with the Self as well as the Ego. This means recognizing and dealing with mythic factors. Although the basic theory in this paper was derived from studying heavy, chronic drug users, it is general in nature and applies to all persons.

Amphetamine↗

[Assessing functional health and sociability of aged persons: the development and validation of two guttman-scales (author's transl)].

Studies to develop and validate two Guttman-scales are reported, which aim at measuring level of functional health and inclination to engage in social contacts in aged persons. A first scale analysis, based on the answers of 150 old persons, resulted in two, 12-item scales, which according to Guttman's criterion were fully satisfying. In two consecutive studies Guttman-selfratings of two other samples of old people were validated against ratings of experts, who disposed of profound knowledge of the sampled persons (a physician of a nursing home, managers of homes for the aged). A second scale analysis was performed, too. The results, especially the very significant correlations between expert ratings and selfassessments, suggest a broader application of at least the functional health scale. It is proposed to use the scales, if one aims at increasing the fit between individual needs and amount of services provided, and as instruments to control for sample characteristics, if different care programs are evaluated.

Aged↗

Clinical characteristics of malignant melanomas developing in persons with dysplastic nevi.

A total of 452 patients with dysplastic nevi (DN) were followed prospectively by repetitive, complete cutaneous examinations in order to determine the clinical features of early malignant melanomas (MM) arising in them. Sixteen patients (3.5%) developed 18 newly diagnosed MM during an average follow-up period of 27 months. Twelve of the 18 MM were in situ and all of the primary invasive MM diagnosed prospectively in this follow-up were less than 0.89 mm in Breslow thickness, implying an excellent prognosis. The principal clinical clue to the diagnosis of MM was change in a preexisting pigmented lesion. Total-body photographs were very useful in helping to identify the early MM in these patients.

Adolescent↗

Correlates of personal concerns about developing Alzheimer's disease among middle-aged persons.

We examine correlates of personal concerns about developing Alzheimer's disease (AD) among (1) adult children, 40 to 60 years of age, who have a living parent with a diagnosis of probable AD (N = 108), and (2) a matched comparison group of persons with no parental history of AD (N = 150). Using stepwise regression, predictors measuring subjective perceptions of memory functioning, overall family history of AD, knowledge of AD, and sociodemographic characteristics were entered into models for the total sample and each of the subsamples. The results indicate that worries about memory functioning play a consistent role in personal concerns about developing AD across both groups, but that additional pathways to personal concerns differ among individuals having and not having a parent with AD.

Adult↗

[The endocrine psychosyndrome in the long term. III. A catamnestic reexamination of patients suffering from hypothalamo-hypopituitary dwarfism (author's transl)].

Fifteen patients (4 females and 11 males) with hypothalamo-hypopituitary dwarfism underwent extensive psychiatric investigation in 1962-1965. A follow-up study of the personality development and social conditions was made in 1977. The age of the patients ranged from 31 to 56 years (the average being 40). As before, the main finding was an infantile personality with a defective psychosexual maturity. Only a few patients had reached a somehat adult, independent personality in spite of hormonal deficiencies. Several patients had continued to grow and attained a stature slightly below average. However, this subsequent growth scarcely influenced personality development. Depressive moods are now more frequent than before and among the more differentiated patients, the neurotic symptoms are mainly phobic fears. Almost all of the patients have discontinued treatment with hormonal substitutes (androgenes, cortison, thyrotropic hormone) inspite of persistent deficiency symptoms, because the outcome did not match their high expectations. The symptoms of the endocrine psychosyndrome seem of minor importance compared with the psychic infantilism and the reactions to the experience of dwarfism and missing puberty. One female has suffered several psychotic episodes which were understood as being partially of endocrine origin.

Adult↗

A longitudinal study of the genetics of personality.

A longitudinal twin study was conducted to determine whether personality traits with significant heritability in adolescence remain so in adulthood. A subsample of a group of twins who had been administered in Minnesota Multiphasic Personality Inventory and the California Psychological Inventory in adolescence was readministered the same two inventories 12 years later. The subsample was found to be representative of the sample from which it was drawn. Different patterns of significantly heritability were found for the two ages studied: Several personality traits demonstrated evidence of significant heritability in either adolescence or adulthood, while others demonstrated evidence of significant heritability at both ages. In addition, genetic influences on the change from adolescence to adulthood were found for several personality traits. The results raise important questions for the interpretation of twin research and the understanding of genetic influences on personality development.

Adolescent↗

Clinical outcomes and cost-effectiveness of strategies for managing people at high risk for diabetes.

BACKGROUND: Lifestyle modification can forestall diabetes in high-risk people, but the long-term cost-effectiveness is uncertain. OBJECTIVE: To estimate the effects of the lifestyle modification program used in the Diabetes Prevention Program (DPP) on health and economic outcomes. DESIGN: Cost-effectiveness analysis using the Archimedes model. DATA SOURCES: Published basic and epidemiologic studies, clinical trials, and Kaiser Permanente administrative data. TARGET POPULATION: Adults at high risk for diabetes (body mass index >24 kg/m2, fasting plasma glucose level of 5.2725 to 6.9375 mmol/L [95 to 125 mg/dL], 2-hour glucose tolerance test result of 7.77 to 11.0445 mmol/L [140 to 199 mg/dL]). TIME HORIZON: 5 to 30 years. PERSPECTIVE: Patient, health plan, and societal. INTERVENTIONS: No prevention, DPP's lifestyle modification program, lifestyle modification begun after a person develops diabetes, and metformin. MEASUREMENTS: Diagnosis and complications of diabetes. RESULTS OF BASE-CASE ANALYSIS: Compared with no prevention program, the DPP lifestyle program would reduce a high-risk person's 30-year chances of getting diabetes from about 72% to 61%, the chances of a serious complication from about 38% to 30%, and the chances of dying of a complication of diabetes from about 13.5% to 11.2%. Metformin would deliver about one third the long-term health benefits achievable by immediate lifestyle modification. Compared with not implementing any prevention program, the expected 30-year cost/quality-adjusted life-year (QALY) of the DPP lifestyle intervention from the health plan's perspective would be about 143,000 dollars. From a societal perspective, the cost/QALY of the lifestyle intervention compared with doing nothing would be about 62,600 dollars. Either using metformin or delaying the lifestyle intervention until after a person develops diabetes would be more cost-effective, costing about 35,400 dollars or 24,500 dollars per QALY gained, respectively, compared with no program. Compared with delaying the lifestyle program until after diabetes is diagnosed, the marginal cost-effectiveness of beginning the DPP lifestyle program immediately would be about 201,800 dollars. RESULTS OF SENSITIVITY ANALYSIS: Variability and uncertainty deriving from the structure of the model were tested by comparing the model's results with the results of real clinical trials of diabetes and its complications. The most critical element of uncertainty is the effectiveness of the lifestyle program, as expressed by the 95% CI of the DPP study. The most important potentially controllable factor is the cost of the lifestyle program. Compared with no program, lifestyle modification for high-risk people can be made cost-saving over 30 years if the annual cost of the intervention can be reduced to about 100 dollars. LIMITATIONS: Results depend on the accuracy of the model. CONCLUSIONS: Lifestyle modification is likely to have important effects on the morbidity and mortality of diabetes and should be recommended to all high-risk people. The program used in the DPP study may be too expensive for health plans or a national program to implement. Less expensive methods are needed to achieve the degree of weight loss seen in the DPP.

Adult↗

Do comparative self-appraisals during young adulthood predict adult personality?

Archival data from the University of North Carolina Alumni Heart Study were used to assess whether positive, neutral, and negative social comparisons assessed during college predicted the expression of personality during adulthood. College students in 1966 rated themselves relative to peers on several personal attributes. For men and women, these attributes produced 3 similar yet distinct variables reflecting gregariousness, achievement striving, and expressiveness. These students were contacted 20 years later and completed the NEO Personality Inventory and M. Rosenberg's (1965) self-esteem measure. In general, persons with comparatively positive self-evaluations during college viewed themselves as possessing more positive and less negative personality traits during adulthood and were also less likely to report poorer self-esteem during middle adulthood. The implications of social comparison processes for personality development are discussed.

Adolescent↗

Midwives' motivation for continuing education.

This study examined midwives' motivations for continuing their education by conducting a survey amongst a sample population of midwives, employed in 4 Health Authorities in the North West of England. The survey was carried out using a questionnaire which asked midwives to indicate the 'importance' of a series of requirements of continuing education. Of 120 midwives who received the questionnaire, 83 (69%) replied. Motivational factors included: learning for professional and personal development; fulfilling legal or statutory practice requirement, or as a social activity. The results showed that motivation for continuing education was strongest in relation to professional competence and an innate desire for knowledge. Where personal development was achieved, the emphasis was to promote professional advancement rather than social interaction. Less emphasis was placed on fulfilling the legal requirements for practice. The strongest motivators were learning orientated, which suggests that the subjects were self-directed to fulfil their needs, based on a desire to learn, this being less dependent on external motivators, which may be activated by statutory or employer requirements. Social interaction was seen as the least important aspect, although subjects found it beneficial to meet colleagues from other areas and felt that they learnt from exchanging views about various clinical practices.

Adult↗

The child is father of the man: personality continuities from childhood to adulthood.

This article presents findings about continuities in personality development that have been uncovered in the Dunedin study, an investigation of a cohort of children studied from age 3 to 21. At age 3, children were classified into temperament groups on the basis of observations of their behavior. In young adulthood, data were collected from study members themselves, from people who knew them well, and from official records. Undercontrolled 3-year-olds grew up to be impulsive, unreliable, and antisocial, and had more conflict with members of their social networks and in their work. Inhibited 3-year-olds were more likely to be unassertive and depressed and had fewer sources of social support. Early appearing temperamental differences have a pervasive influence on life-course development and offer clues about personality structure, interpersonal relations, psychopathology, and crime in adulthood.

Adult↗