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[Nail polish allergy. An important differential diagnosis in contact dermatitis].

HISTORY AND CLINICAL FINDINGS: Case 1. A 34-year-old woman presented with a recurrent, itching and erythematous plaque on her right cheek. Case 2. A 27-year-old woman reported itching erythema on her fingertips from time to time recently. Inspection revealed dyshidrosiform blisters. Both patients had been using nail varnish and varnish remover. Case 3. A 49-year-old woman had, for about 5 years, repeatedly experienced itching erythema at the perionychium of several fingers on which she had placed artificial nails. Marked oedema and erythema was noted. INVESTIGATION: Extensive epicutaneous tests were performed on these patients. They showed sensitisation against important allergens in nail varnish (toluolsulphonamide-formaldehyde resin), nail varnish remover (benzophenone-2) and artificial nails (ethylacrylate), respectively. The three patients also showed type IV sensitisation against other substances. DIAGNOSIS, TREATMENT AND COURSE: Epicutaneous tests documented type IV allergies to important constituents of nail varnish, nail varnish remover and artificial nails. Symptoms and skin changes disappeared when these three items were no longer used. CONCLUSION: Allergies against nail varnish and its remover and against artificial nails should be included in the differential diagnosis of skin allergies, even when patients have additional type IV sensitizations against common allergens. As the causative allergen can be easily avoided, knowledge of the particular problems associated with these allergies is of a great practical significance.

Adult↗

Modified Emmet's operation for ingrown nails using the Er:YAG laser.

BACKGROUND: Ingrowing nails are a common problem. Standard procedure is surgery according to Emmet (a gynecologist) or Emmert (a surgeon) where postoperative pain, swelling and bleeding are major side effects and traumatic damage of the nail organ is not completely avoidable. Laser surgery may provide an alternative with less tissue damage. METHODS: We compared 138 patients with 212 affected great toe nails (98 males, 40 females) were bloodless Emmet's operation was performed with digital nerve block with 11 patients (12 affected nails) using an Er:YAG laser for atraumatic nail plate removal. Pain was registered by a semiquantitative pain scale (ranging from "zero--no pain" to "10--maximum pain"). Swelling was scored from "0--absent" to "3--severe". Side effects like bleeding, infection or relapse were registered. RESULTS: Emmet's nail operation: Pain was scored 7.8+/-3.2 on the operation day (evening), 5.3+/-3.1 (day 1) and 3.8+/-4.0 (day 3). Swelling was scored 2.7+/-1.8 (operation day, evening), 2.1+/-1.9 (day 1) and 1.3+/-2.1 (day 3). Wound healing lasted 16.8+/-3.3 days. The infection rate was 2.4%, i.e. 5 of 212 nails. The relapse rate after 6 months was 12 of 212 nails (5.7%). Spicules were observed in 9 of 212 nails (4.2%). Laser procedure: Pain was scored 8.0+/-1.9 (operation day, evening), 4.1+/-1.5 (day 1) and 0.7+/-2.3 (day 3). The swelling was scored 2.4+/-1.8 (operation day, evening), 1.5+/-0.9 (day 1) and 0.9+/-1.3 (day 3). Wound healing was complete after 12.9+/-3.5 days. Infections and relapse were not observed. In one case spicules occurred after 5 months. No other side effects were noted. CONCLUSIONS: The modified Emmet's operation for ingrown nails using the Er:YAG laser provides a safe method with increased efficacy that causes less pain and swelling, a faster healing and less complications.

Adolescent↗

Cross-linked envelopes in nail plate in lamellar ichthyosis.

BACKGROUND: Corneocytes of the nail plate, like those of the stratum corneum, generate cornified envelopes (CEs) of cross-linked protein that can be visualized readily after removal of non-cross-linked protein by detergent extraction. Defective CE formation occurs in epidermal scale and hair in transglutaminase 1 (TGM1)-negative lamellar ichthyosis (LI) and has been proposed as a diagnostic aid for this syndrome. OBJECTIVES: (i) To ascertain whether TGM1 is important for CE formation in nail; (ii) to characterize CE abnormalities occurring in LI that may be distinguished from other types of inherited ichthyosis when nail samples are subjected to detergent extraction; and (iii) to evaluate the utility of nails as a diagnostic aid for LI. METHODS: Nail samples were provided by nine patients previously classified as having TGM1-negative LI, four with other types of ichthyotic conditions and six normal controls. Samples were extracted extensively in sodium dodecyl sulphate under reducing conditions and examined by light and electron microscopy. RESULTS: After extraction, defective CE cross-linking was visualized in epidermal corneocytes from seven of nine patients exhibiting TGM1-negative LI, whereas nail samples from patients with the other syndromes were normal. The defects in CE structure resembled those recently reported for LI scale, although in some cases residual CE and CE-associated structures were present. CONCLUSIONS: Despite the paucity of clinical nail symptoms in LI, TGM1 activity is important for generation of normal CE in nail plate, consistent with its importance in protein cross-linking in interfollicular epidermis and hair. Lack of this activity leads to a strikingly aberrant appearance of CE in LI nail after detergent extraction that is evident ultrastructurally in a large majority of cases. Nail envelopes therefore could provide a useful diagnostic tool in distinguishing LI from other ichthyoses with overlapping clinical features.

Diagnosis, Differential↗

Vertically growing ectopic nail.

A 64-year-old Japanese woman with an ectopic nail at the palmar tip of the left middle finger is reported. Interestingly, the nail grew vertically to a line horizontal to the surface epidermis. Atypically, it appeared at 60 years of age with no prior injury or trauma to explain inoculation of a nail matrix into the regional skin. Roentgenographically, there were no abnormal findings such as Y-shaped bifurcation of the distal phalanx of the affected finger. There are conflicting opinions concerning whether or not a proximal nail fold is critical for the nail to grow outward instead of upward. Although the present case had a wide proximal nail fold, it did not seem to play its role of compressing and assisting the nail plate to grow outward. Hence, it may be that the absence of a proper nail bed, rather than the absence of a proximal nail fold, promotes upward growth of a nail plate instead of outward growth.

Choristoma↗

The nail dystrophy of psoriatic arthritis.

Nail abnormalities occur frequently in patients with psoriatic arthritis. This study of the finger nails of 46 patients with psoriatic arthritis, 100 nonpsoriatic rheumatism patients, and 100 nonpsoriatic general medical patients was designed to characterise these abnormalities with particular reference to the severity of nail pitting. The results of the study suggest: (1) Onycholysis alone in the absence of previous injury to the affected nail is in favour of a psoriatic origin for the nail dystrophy. (2) Two or all of onycholysis, horizontal ridging, and nail pitting in the same patient are in favour of a psoriatic origin for the nail dystrophy. (3) The presence or absence of nail pitting alone is a poor discriminator between psoriatic and other causes for nail dystrophy. (4) More than 20 finger nails pits per person is suggestive of a psoriatic cause for the dystrophy. (5) More than 60 pits per person is unlikely to be found in the absence of psoriasis.

Arthritis↗

Deformation of femoral nails with intramedullary insertion.

Current methods of distal interlocking of intramedullary femoral nails are dependent on image intensification. However, radiation exposure to the patient, the operating room staff, and the surgeon remains a concern. Proximally mounted, radiation-free aiming systems for distal interlocking of femoral nails have reportedly failed because of nail deformation with insertion. To better understand this deformation, a three-dimensional magnetic motion tracking system was used to determine the position of the distal interlocking hole following nail insertion. The amount and direction of deformation of commercially available small-diameter implants (unslotted 9-mm nails inserted without reaming) and large-diameter implants (slotted 13-mm nails inserted with reaming) from a single manufacturer were analyzed. Measurements of deformation (three translations and three angles), based on the center of the distal transverse locking hole, were performed on 10 paired intact human cadaveric femora before and after insertion. The technique produced the following results for the small and large-diameter nails, respectively: lateral translations of 18.1+/-10.0 mm (mean+/-SD, range: 47.8 mm) and 21.5+/-7.9 mm (range: 26.4 mm), dorsal translations of -3.1+/-4.3 mm (range: 15.2 mm) and 0.4+/-9.8 mm (range: 30.1 mm), and rotation about the longitudinal axes of -0.1+/-0.2 degrees (range: 0.7 degrees) and 10.0+/-3.1 degrees (range: 7.8 degrees). This technique is useful for measuring insertion-related femoral nail deformation. The data for the nails tested suggest that a simple aiming arm, mounted on the proximal end of the femoral nail alone, will not sufficiently provide accurate distal aiming.

Bone Nails↗

Effects of nail rigidity on fracture healing. Strength and mineralisation in rat femoral bone.

The present study was undertaken to assess the effects of the rigidity of nails on the healing of fractures as evaluated by mechanical strength and rate of bone mineralisation. Ten rats supplied biomechanical data at the start of the experiment and another 100 rats were randomly assigned to 5 groups. In 20 rats no intervention was performed, and they served as a reference group of normal values. Thus, 80 rats underwent a standardised partial osteotomy in the left femur diaphysis prior to manual fracture, reaming and intramedullary nailing. One group received rigid steel nails (group 1) and another, cannulated steel nails (group 2). Group 3 received semi-rigid titanium nails and group 4, soft polyethylene nails. Ten rats in each group were evaluated at 6 and 12 weeks after fracture, and radiographs and callus diameter measurements were performed. Dual-energy X-ray absorptiometry (DEXA) of the bones was performed, and the degree of mineralisation in the callus segment, distal diaphysis and total femur was calculated by the scanner. Subsequently, the bones were tested mechanically by a three-point bending test in a Mini Bionix (MTS) testing system. Radiographs revealed clearly visible fractures at 6 weeks in the intervention groups. At 12 weeks there were no signs of bridging callus in group 4, while the other groups presented scarcely visible osteotomies. The callus area in group 4 was significantly larger at both 6 and 12 weeks than in groups 1-3. In these groups there was a significant decrease in callus area between 6 and 12 weeks. Both maximum bending load, bending rigidity and fracture energy increased significantly in groups 1-3 between 6 and 12 weeks, while bending load and fracture energy increased in group 4. At 6 weeks no significant differences were detected between groups 1-3 in mechanical strength. Group 4 had a significantly reduced maximum bending load and fracture energy at 6 and 12 weeks as well as bending rigidity at 12 weeks. At 12 weeks group 3 had a significantly increased maximum bending load and fracture energy compared with groups 1 and 2. Bone mineral count (BMC) in the callus region in group 4 was significantly reduced at both 6 and 12 weeks. BMC in the callus showed no significant differences between groups 1-3, either at 6 or at 12 weeks. BMC in the distal diaphysis was significantly reduced in groups 1 and 4 compared with group 2 at 12 weeks. Bone mineral density (BMD) in the callus region revealed no significant differences between groups 1-3 at 6 weeks, while at 12 weeks BMD was higher in group 3 than in group 1. BMD in the callus region and total femur in group 4 was significantly reduced at 6 weeks. This study demonstrates that diaphyseal fractures treated with titanium nails with a bending rigidity similar to the intact femur have a higher maximum bending load and fracture energy at 12 weeks than both rigidly or softly nailed fractures. BMD in the callus region was also highest after titanium nailing at 12 weeks. BMD in the distal diaphysis and total femur indicates that the degree of stiffness of the nails have little influence on total bone mineralisation at 12 weeks.

Absorptiometry, Photon↗

A review of biomechanical studies of intramedullary nails.

Fracture management is becoming less conservative, and more frequently surgical intervention is the treatment of choice. Intramedullary mailing is a modern surgical method of internal fracture used in long bones such as the femur, tibia and humerus. The nails' function is to stabilize the fracture fragments, allowing load transfer across the fracture site while maintaining anatomic alignment of the bone. There are a large number of different intramedullary nails available commercially but no universal guideline stating the conditions at which each nail will perform at its optimum. Numerous animal, biomechanical and clinical studies have documented the performance of the nails. Biomechanical studies have shown that in torsion, slotted nails have a considerably lower rigidity than non-slotted nails but that in bending, the slot makes little difference to the nails' behaviour and so the two nail types have similar stiffnesses. Studies also recommend that in unstable fractures an interlocked intramedullary nail is essential if limb shortening or malunion is to be avoided. It is the aim of this review to outline the work that has been published to date on the biomechanical testing of intramedullary nails and to highlight areas that require further investigation.

Biomechanical Phenomena↗

Femoral exchange nailing for aseptic non-union: not the end to all problems.

We report the results of a single centre prospective study of exchange nailing for aseptic non-union of a femoral fracture. Eighteen patients with 19 aseptic femoral non-unions had exchange nailing performed in our institution. We collected data on mechanism of injury, original fracture type, and indication for exchange nailing, further surgery and major complications. In 11 non-unions (58%), the exchange nail procedure alone resulted in fracture union with a mean time to radiographic union of 9 months (range 3-24 months). The non-union did not heal in five patients, two patients developed an infected non-union, and one patient required dynamisation of the exchange nail. Fracture healing was eventually achieved in 18 non-unions (95%). Complications following exchange nailing occurred in 11 fractures (58%), in which further surgery was required (four repeat exchange nailings, two Ilizarov frame applications and five nail removals). The role of reamed exchange nailing in the treatment of femoral non-union needs to be re-evaluated. Although fracture healing is eventually achieved in most patients, a significant number of them required additional surgery to achieve union or to deal with complications arising from the exchange nailing.

Adolescent↗

Characterization of cultured nail matrix cells.

BACKGROUND: Cultures of epidermal cells are commonly used to study skin biology and differentiation. Recently a method to culture nail matrix cells has been established. OBJECTIVE: We report the biologic characteristics of nail matrix cells in vitro compared with those of epidermal keratinocytes. METHODS: Human nail matrix cells were isolated and cultured in defined medium. Electron-microscopic examination, growth rate, integrin expression and keratin synthesis pattern were evaluated. In addition, the cells were cultured in serum-containing medium. RESULTS: Nail matrix cells appear to be larger than human epidermal keratinocytes and, at the ultrastructural level, they contain a higher euchromatin/heterochromatin ratio and a lower nucleus/cytoplasm ratio and have a higher growth rate. The synthesis of "hard" keratins was detected at all calcium concentrations. Immunofluorescence analyses showed the expression of alpha 2, alpha 3, and alpha 6 integrin subunits. When cultured in serum-containing medium, nail matrix cells produced an outgrowth of epithelium and a spontaneous migration phenomenon associated with a tendency to stratify in a semilunar area that resembles the architecture of the nail matrix. The pluristratified epithelium showed characteristic markers of nail differentiation. CONCLUSION: Culture of nail matrix cells may represent a useful model to study the biologic properties of nail structure, alterations in some nail diseases and the effects of drugs.

Cell Division↗

Racial differences in nitrogen content of nails among adolescents.

Ectodermal derivatives provide a readily accessible means of chemically evaluating body protein composition. Therefore, it has been postulated that the analysis of nail nitrogen content may reflect recent nutritional status. Assessment of nail nitrogen content has been previously reported in a small group of neonates and school children. The present study was undertaken to determine if standards for nail nitrogen content could be established for adolescents which could then be used in the assessment of protein nutritional status. Nail clippings were obtained from 118 economically indigent urban black youth, 10 black and 39 white subjects from wealthy suburban communities in the New York area, and 10 poor white-Indian adolescents residing within a barrio in Lima, Peru. Nail samples were analyzed for protein content using the micro Kjeldahl technique. Mean nail nitrogen content for wealthy suburban and impoverished urban black youth was 136 and 137 mg N/g of nail, respectively. Values for poor Peruvian white-Indian and affluent suburban white adolescents were 142 and 141 mg N/g of nail, respectively. The differences between ethnic groups were significant using t test analysis at a P value of less than 0.001. No differences, however, were found between either wealthy and poor of the same racial background or when the data were analyzed by gender. These results suggest that differences in nail nitrogen content are at least in part a reflection of ethnicity. These racial differences must be considered in assessing nutritional status by nail nitrogen analysis.

Adolescent↗

Retrograde reamed femoral nailing.

Closed, reamed, antegrade nailing remains the standard of care for femoral shaft fractures. This technique however, may be less attractive in the management of femoral shaft fractures associated with (a) ipsilateral acetabular, pelvis, or femoral neck fractures; (b) polytrauma requiring multiple simultaneous surgical procedures; and (c) pregnancy. We now report on our experience with the retrograde femoral nailing as a treatment option in these situations. Between 4/88 and 10/90, 29 retrograde femoral nailing in 24 patients were attempted. Average age was 29.3 (16-74) years. Five fractures were open. Fracture location was isthmal in 14 and infraisthmal in 15. The comminution was classified according to Winquist and Hansen: I(10), II(7), III(7), and IV(5). Nailing was possible in 28/29 cases. Insertion was made through an extraarticular medial condylar portal. Nail diameter ranged from 10 to 13 mm. An AO Universal Femoral Nail was used in the first 11 cases; all subsequent fractures were stabilized using an AO Universal Tibial Nail because its design appeared better suited to this technique. Follow-up was possible for 25 fractures in 21 patients and averaged 16.0 (range, 11-27); months 23/25 (92%) fractures healed within 12 weeks. No case was associated with an infection, loss of reduction, or nail failure. Knee flexion averaged 122 degrees; only two knees had an extensor lag of > 5 degrees. Intraoperative complications included three cases of crack propagation at the insertion site, and four infraisthmal malreductions (two valgus, two flexion). Based on these results, we feel that retrograde reamed femoral nailing is a suitable alternative to antegrade nailing and should be considered in situations where proximal access is neither possible nor desirable.

Acetabulum↗

Immediate interlocking nailing of fractures of the femur caused by low- to mid-velocity gunshots.

A retrospective review of 39 fractures of the femur in 37 patients caused by low- and mid-velocity handgun missiles treated with static interlocking nailing within 18 h of injury was conducted to evaluate the efficacy, safety, and cost savings of immediate intramedullary nailing in these injuries. Patients were followed through union of the fracture with an average follow-up of 12.5 months. The average hospitalization was 8.5 days. All but two fractures healed in an average of 14 weeks (range 8-28). One delayed union was treated with exchange intramedullary nailing with reaming 5 months postinjury and progressed uneventfully to fracture union. One nonunion occurred, presenting with broken distal interlocking screws 18 months after injury, which was treated with an exchange intramedullary nailing with reaming. The nonunion healed within 4 months of this secondary procedure. There were no malunions of > 5 degrees angulation, no leg length discrepancies of > 1.0 cm, and no rotational malalignments noted. There was one (2.5%) infection that was successfully treated with nail removal, reaming of the canal, and reinsertion of a larger diameter nail. We conclude that immediate interlocking nailing of low- and mid-velocity gunshot fractures of the femur is an effective and safe treatment. Compared with previously published data on intramedullary nailing of femoral gunshot fractures, immediate intramedullary nailing resulted in a shorter hospital stay with a significant decrease in hospital expenses. Because the findings of this study indicate that early fixation in these injuries had no detrimental effect on the clinical results, we recommend immediate intramedullary nailing of gunshot fractures of the femur.

Adolescent↗

Fatigue properties of a twelve-hole versus a five-hole intramedullary supracondylar nail.

OBJECTIVES: To evaluate a design change intended to improve fatigue properties of Intramedullary Supracondylar nails (IMSC). DESIGN: Fatigue testing was performed on 12-hole and 5-hole IMSC nails in 18 plastic-fiber composite femurs. Fractures were simulated by a 1 cm wide osteotomy. Nails were cycled until failure with femoral loads ranging from 133 N to 1869 N (30 to 420 lb.) for the 12 mm nails and 133 N to 1335 N (30 to 300 lb.) for the 11 mm nails. A simple finite element computer model (FEM) was also created to determine the difference in stress distribution between the two designs. SETTING: All mechanical testing was performed using a servohydraulic test fram (MTS Systems, Minneapolis, MN). The FEM was performed using I-DEAS software (SDRC, Milford, OH) running on an Apollo 9000/735 workstation (Hewlett-Packard, Palo Alto, CA). INTERVENTION: The nails were locked proximal and distally. MAIN OUTCOME MEASUREMENT: The number of cycles to failure and the maximum tensile stress (FEM) was measured and compared between the two designs. RESULTS: The 11 mm and 12 mm 12-hole nails failed at an average of 53,514 cycles and 102,433 cycles respectively. No nail failures were seen in the 5-hole design. The FEM showed a 400% increase in maximum tensile stress due to the transverse screw hole in the cannulated nail. CONCLUSIONS: Elimination of screw holes at the level of a supracondylar metaphyseal defect significantly improves the fatigue life of the IMSC nail.

Biomechanical Phenomena↗

Cortical bone blood flow in loose and tight fitting locked unreamed intramedullary nailing: a canine segmental tibia fracture model.

OBJECTIVES: To quantitatively determine the extent to which loose and tight fitting unreamed, locked intramedullary nails devascularize cortical bone and to determine their effect on early strength of union. DESIGN: A 2.5-centimeter segment of devascularized diaphyseal bone was created in the tibiae of twelve skeletally mature mongrel dogs by means of two standardized transverse osteotomies. Stabilization of the tibia was achieved with either a 5.0-millimeter (n = 6) or a 6.5-millimeter (n = 6) unreamed, locked intramedullary nail. Bone blood flow was assessed using laser Doppler flowmetry. Bending stiffness and load to failure were determined for each healed tibia. RESULTS: At the conclusion of the nailing procedure, the overall tibial blood flow was reduced by 58 percent and 72 percent for the 5.0-millimeter and 6.5-millimeter nail groups, respectively (p = 0.001, p = 0.00004). Perfusion was reduced to a greater extent in the tightly fitting nail group (p = 0.017). At eleven weeks postnailing, cortical perfusion increased in both the 5.0-millimeter and the 6.5-millimeter nail groups (p = 0.005, p = 0.002, respectively). Perfusion increased to a higher level in the loosely fitting nail group (p = 0.007). Biomechanical properties of the healed tibiae, including bending stiffness in two planes and load to failure, were similar in the two experimental groups (p = 0.42, p = 0.09, p = 0.34). DISCUSSION: Our results demonstrate that a loose fitting nail spared cortical perfusion at the time of nail insertion more than did a canal filling nail and allowed more complete cortical reperfusion at eleven weeks postnailing. The results of this study have implications for the treatment of severe tibial shaft fractures in which the blood supply is significantly compromised.

Animals↗

Intraarticular anatomic risks of tibial nailing.

OBJECTIVE: To identify the risks to intraarticular structures of the knee during tibial portal creation and to identify the safe zone for tibial nail placement. STUDY DESIGN: Cadaveric anatomic. LOCATION: University trauma center. METHODS: Forty fresh frozen cadaveric knees were studied to elaborate the risks of tibial portal creation and nail placement to the intraarticular structures of the knee. Nails were placed through medial and lateral parapatellar approaches, and the distance from the nail portal to the intraarticular structures of the knee was measured. A safe zone for portal placement was determined. RESULTS: The tibial portal location averaged 4.4+/-3 millimeters lateral to the midline of the plateau. Actual intraarticular structural damage occurred in 20 percent of the specimens; however, an additional 30 percent demonstrated the nail to be subjacent to one of the menisci. A lateral paratendinous approach placed the lateral articular surface at most risk, and a medial paratendinous approach placed the medial meniscus at most risk. The safe zone for nail placement was identified and is located 9.1+/-5 millimeters lateral to the midline of the plateau and three millimeters lateral to the center of the tibial tubercle. The width of the safe zone averaged 22.9 millimeters and was as narrow as 12.6 millimeters. CONCLUSION: Damage to the intraarticular structures of the knee is possible during tibial nailing with a superior portal. The safe zone for nail placement is small and can be exceeded if a reamed nail is used. The safest starting point for tibial nailing should be slightly lateral to the center of the tibial tubercle.

Bone Nails↗

Biomechanical analysis of supracondylar femoral fractures fixed with modern retrograde intramedullary nails.

OBJECTIVES: Several new retrograde supracondylar intramedullary nails have been developed to specifically address fractures of the distal femur. The nails appear clinically effective, but there are few biomechanical data documenting the stability of the fixation or the mechanical stiffness of the different designs. The goal of this study was to assess the torsional and bending stiffness of four designs of intramedullary nails developed for this application. METHODS: Four nail designs were tested in torsion and bending to determine system stiffness: Ace supracondylar, Richards "five hole" and "multi-hole" supracondylar, and Biomet retrograde. The nails were inserted into cadaveric femurs in which a one-centimeter distraction osteotomy had been created seven centimeters proximal to the condyles. The constructs were then tested on an Instron biaxial testing system. RESULTS: There were no statistically significant differences in bending stiffness among the groups of nails (range 0.79 to 1.18 newtons/meter; p > 0.1). However, the Ace nails (1.10 newtonmeters/degree) did exhibit a statistically lower torsional stiffness compared with the other nails (2.20 to 2.21 newton-meters/ degree; p < 0. 1). No differences were noted as a function of the number of locking holes. CONCLUSIONS: The bending stiffness of four currently available designs of retrograde intramedullary nails does not appear to be dependent on design variations. The torsional stiffness did vary among the four designs, but this was not determined by the number of fixation holes provided. It appears that a well-placed retrograde supracondylar nail of modern design should have sufficient stiffness to support the femur and provide stability during fracture healing.

Biomechanical Phenomena↗

Unreamed locked tight-fitting nailing for acute tibial fractures.

OBJECTIVES: Treatment of tibial fractures by unreamed locked nailing with loose-fitting nails has previously been shown to be associated with a low union rate and high implant failure rate. This report describes the authors' experience in using tight-fitting nails that were relatively larger than loose-fitting nails. DESIGN: Prospective cohort study. SETTING: University medical center. PATIENTS: Forty-eight consecutive patients with fifty-two tibial fractures (excluding open IIIC fractures and those with bone loss) were studied: thirty-four men and fourteen women, with a mean age of 38 years. There were twenty-five closed fractures, nine Type I, eight Type II, four Type IIIA, and six Type IIIB open fractures. INTERVENTION: Unreamed nailing with tight-fitting nails using the Russell-Taylor system. OUTCOME MEASURES: Union rate, time to union, complication rate, and functional recovery, as well as nailing time, hospital time, and crutch-walking time were recorded. RESULTS: Union occurred in forty-eight of fifty-two fractures (92%) with a mean time to union of 18.2 weeks. Compartment syndrome occurred in three patients. Deep infection occurred in one Type II and one Type IIIB open fracture. Four fractures required additional exchange nailing or bone grafting to achieve union: one Type II, one Type IIIA, and two Type IIIB open fractures. Three malalignments resulted from operative technical error. The rate of both intraoperative bony split and screw breakage was 3.8% (2 of 52), but neither complication interfered with fracture healing. Recovery of joint motion was essentially normal in those patients without knee or ankle injury. CONCLUSIONS: Unreamed locked nailing with tight-fitting nails can produce satisfactory clinical results for acute tibial fractures. It has the advantages of technical simplicity and an acceptable risk of implant failure.

Acute Disease↗