Twins and growth of dento-facial structures.
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The oral apparatus of neonatal and juvenile golden hamsters was investigated by clearing and staining of whole crania, videotaping of behavior, and electromyography of several jaw muscles. Chewing developed during the first postnatal week and matured in the second; however, suckling was still the primary mode of feeding. Micromovements of the jaws occurred early when the osseous skeleton and joints developed. Macromovements correlated well with EMG records and were limited to jaw opening at birth. Muscles of the oral floor generated large bursts of activity during jaw opening and tongue protrusion from 0 days postnatal (dpn), when simple and stereotyped gaping was induced, until 14 dpn, when movements were spontaneous and not stereotyped nor inducible. However, adductor muscle activity was brief, low in amplitude, and primarily involved with jaw stabilization until 4 dpn, when these muscles became active during closing the jaws; closing activity increased in frequency and amplitude until the end of the second week. Development of frequent, coordinated macromovements of chewing was associated with the refinement of joint structure and dental occlusion and with the growth of the craniofacial skeleton. Jaw movements and associated EMG's correlated better with available data on development of neural circuitry than with that for musculoskeletal development.
The surgical correction of nasal septal deviation observed in children is usually postponed until adult age presumably on the assumption of interference with facial growth. In order to elucidate this hypothesis, the entire basis of the cartilaginous nasal septum and vomer was extirpated in a group of growing domestic cats. The operation resulted in a basally unsupported septum being separated from the palatal halves by loose connective tissue. The sagittal mid-facial growth in these animals was then compared with that of sham-operated and unoperated controls. From measurements on lateral skull radiograms, taken at the start and end of the experiment, no difference in sagittal mid-facial development could be found among the three groups. The findings suggest that growth of the nasal septum/vomer, at least at its basal parts, is not involved in facial development during the period from infancy to adulthood.
This paper recommends that the development of deciduous teeth in patients with extensive unilateral clefts should be studied by reference to jaw models and compared with results obtained by Heckmann in a series of investigations of regular sets of deciduous teeth and that such studies should be made on the model of those which were conducted, in recent years, by workers at the Rostock Department of Orthopedic Stomatology and which were concerned with questions associated with the normal development of dentures.
The effects of unilateral facial nerve ablation on craniofacial development in the rabbit were examined. In this experimental model, 10 newborn rabbits 12 days of age underwent unilateral resection and cautery of the facial nerve. They were allowed to grow to skeletal maturity and were sacrificed at 6 months. Analysis of variance was used to compare direct measurements of prepared skulls in the experimental animals with 3 unoperated control litter mates and with 5 litter mates who underwent a sham procedure (exposure of the facial nerve without section). The animals with facial nerve resection demonstrated an average snout deviation toward the side of injury of 8.3 degrees, apparently due to shortening of the maxilla and mandible on the affected side. This study provides new data regarding the role of the functional matrix in the modulation of craniofacial growth and development.
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