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Isolation of caprine arthritis encephalitis virus from goats in Mexico.

A lentivirus was isolated from 2 goats in Mexico that were seropositive to caprine arthritis encephalitis virus (CAEV) by the agar gel immunodiffusion (AGID) test. The lentivirus was identified as CAEV by the observation of giant multinucleated cells (syncytia) in goat synovial membrane (GSM) monolayers co-cultivated with blood mononuclear (BMN) cells from the seropositive goats, and by amplifying a DNA segment of the CAEV gag gene using the polymerase chain reaction (PCR) technique. Subsequently, cell supernatants from the GSM cells co-cultivated with BMN cells were used to infect 2 CAEV-seronegative goats. These goats seroconverted to CAEV as determined by the AGID test, and CAEV was re-isolated from these goats. One of the goats developed polyarthritis 8 mo after inoculation. Previous serological surveys indicate that infection with CAEV is prevalent among goats in Mexico. To our knowledge this is the first report of CAEV isolation in Mexico. Because of globalization of markets and increased trading among nations, the rapid identification and reporting of diseases such as CAEV are important to prevent the dissemination of these diseases.

Amino Acid Sequence↗

[Historical notes on the beginning of experimental surgery in Mexico (1918-1936)].

This is a historical review from 1918 to 1936 concerning the early papers written in Mexico on experimental surgery. From them, we can learn how Mexican surgeons attempted to repeat the results of authors U. S. and Europe. Additionally, the problem of not having good statistical information in Mexico is illustrated. These papers were published in Mexican journals of limited circulation or in graduation theses. The most important works were ureteroplasties repair in humans with canine tissues (F. Quiroz, 1919). Physical aspects of abdominal sepsis (C. Robles, 1929), and bile duct prosthesis, (Gómez Guerra, 1932). This paper pays homage to Mexican surgeons who in spite of enduring financial difficulties and times of political turmoil, achieved the beginning of these areas of surgery in Mexico.

Animals↗

[Maximal cardiac rate during treadmill exertion test in 1853 healthy subjects. Its relation with age and under the atmospheric conditions of Mexico City].

INTRODUCTION: The relation between heart rate and age during the exercise test is dependent on the altitude over the sea level in which the test is made. OBJECTIVE: To observe the behavior of the heart rate during a maximal exercise test and its relation to age and to the altitude of Mexico City. METHOD: Observational, non randomized study of 1,853 healthy subjects who underwent maximal exercise test done with Bruce's protocol, in the Department of Cardiology of the Spanish Hospital of Mexico City. RESULTS: The distribution by age groups showed a normal curve. They were divided by gender (67% males and 33% females) with a mean age of 47.6 +/- vs 49.6 +/- 13.7 years respectively (p = 0.003). Maximal heart rate according to gender (167.9 +/- 17.4 vs 160 +/- 18.2 bpm, p = 0.001). Trained vs sedentary (85.7% vs 14.3%). Maximal heart rate by grade of training (169.1 +/- 16.4 vs 167.6 +/- 17.8 bpm, p > 0.05) and the lineal correlation of maximal heart rate dependent on age of the subject (r-0.61, Y = 204.37 + (-0.810*X), p = 0.001). CONCLUSIONS: The maximal heart rate during maximal exercise test at the altitude of Mexico City is lower than those reported in the literature. This is statistically significant and depends on age and it does not bear any relationship to the degree of training, at least in our subgroup of subjects studied. The same is true for females and the dependence on age remains the same too.

Adolescent↗

[Validity and reproducibility of a questionnaire on physical activity and non-activity for school children in Mexico City].

OBJECTIVE: To assess the validity and reproducibility of a self-reported questionnaire on physical activity and inactivity, developed for children aged 10-14 in Mexico City. MATERIAL AND METHODS: Between May and December 1996, a self-reported physical activity and inactivity questionnaire was developed and applied twice to a sample of 114 students aged 10 to 14, from a low and middle income population of Mexico City. The children's mothers completed the same questionnaire, and two 24-hour recalls of physical activity were used for comparison. Statistical analysis consisted of central tendency and dispersion measures and Pearson's correlation coefficient. RESULTS: Correlations between hours per day spent in physical activity and inactivity from the children's questionnaire and the 24-hour recall data, were 0.03 for moderate activity, 0.15 for vigorous activity, and 0.51 (p = 0.001) for watching television, adjusted by age, gender, town, and illness prior to the administration of the questionnaire. Compared to the 24-hour recall data, the questionnaire overestimated the time spent watching television, reading or participating in vigorous activity, and underestimated the time engaged in moderate activity. Statistically significant (p < 0.05) six-month reproducibility values were observed for watching television (r = 0.53), sleeping (r = 0.40), moderate (r = 0.38), and vigorous activity (r = 0.55). CONCLUSIONS: Among children of Mexico City aged 10-14, the questionnaire showed acceptable validity in estimating the time watching television, and acceptable reproducibility of the time watching television, vigorous and moderate activity.

Adolescent↗

Measles, rubella, and congenital rubella syndrome--United States and Mexico, 1997-1999.

In 1996, the Immunization Working Group of the Mexico-United States Binational Commission was established to enhance coordination of disease surveillance, assure high vaccination coverage in both countries, and hasten the elimination of vaccine-preventable diseases. The United States and Mexico share the Pan American Health Organization (PAHO) goal of measles elimination by 2000. The United States also established a goal of eliminating indigenous rubella and congenital rubella syndrome (CRS) by 2000. This report summarizes the measles and rubella vaccination and surveillance data for the United States and Mexico for 1997-1999.

Adult↗

[Incidence of acute leukemia in children in Mexico City, from 1982 to 1991].

OBJECTIVE: To measure the incidence rate and trend of acute leukemia (AL) in political districts of Mexico City. MATERIAL AND METHODS: Descriptive longitudinal study conducted at six hospitals that care for nearly 97.5% of all cancer cases among children in Mexico City. Study data were collected in 1995 and 1996, and were analyzed in 1999, at the National Medical Center "Siglo XXI" Children's Hospital, of the Mexican Institute for Social Security. Calculations of acute leukemia annual incidence rates, standardized rates, and standardized morbidity rates (SMR) with 95% confidence intervals, were obtained for each district. Morbidity trends were assessed through average change rates. RESULTS: In this study we observed an increasing trend of acute lymphoblastic leukemia (ALL) incidence in five districts: Alvaro Obregon, Cuauhtemoc, Gustavo A. Madero, Iztacalco, and Venustiano Carranza. Acute myeloblastic leukemia (AML) showed no significantly statistic increase of incidence in any district. AML did show a significant SMR in Alvaro Obregon district (SMR = 2.91, 95% CI 1.63-4.80). Higher SMRs were found in the south and southwest areas of the city. CONCLUSIONS: Increasing incidence of ALL was observed in five districts of Mexico City. AML incidence was the highest in Alvaro Obregon district.

Adolescent↗

[Identification of malignant breast lesions in Mexico].

OBJECTIVE: To evaluate the modes of detection of breast malignancies in Mexico City and to estimate the number of patients diagnosed in advanced stages. MATERIAL AND METHODS: This cross-sectional study was conducted between 1994 and 1996, among 256 women with a histological diagnosis of breast cancer, at three tertiary level public hospitals in Mexico City. Personal interviews were conducted to collect data on reproductive characteristics, clinical history, and breast cancer modes of detection. Data analysis consisted of percentages, odds ratios, and 95% confidence intervals. RESULTS: Ninety percent of women sought medical care after identifying a breast lump by themselves. Only 10% of patients had a stage-I tumor; all 27 cases first identified by a physician were in stage II-B and higher. CONCLUSIONS: An increasing trend of breast cancer mortality in Mexico City will persist, unless a greater proportion of tumors in situ is detected; this would require enhancing breast cancer screening programs and conducting an intense educational intervention among women at risk.

Adult↗

[Content and absorption of calcium in diets of Northwestern Mexico: a bibliographic retrospective].

Calcium is an essential mineral in humans for growth and development of bones and teeth. In adults, bone activity is limited to maintaining bone mass and in order to do this, an adequate intake of calcium is necessary. The objective of this study was to conduct a review of the information available in the literature on the content and availability of calcium in the diet in Northwestern Mexico. The diet studies show that the amount of calcium (1164 mg/d) in the diets in Northwestern Mexico meets the RDA for adults 25 or older and that the principal sources of calcium are corn tortillas, wheat flour tortillas and beans. Bioavailability of calcium in diets containing these foods increases when small amounts of dairy products are added to the diet. This same difference in the availability of calcium was observed in an in vivo study conducted in young women. We can conclude, based on the studies mentioned, that it is necessary to evaluate the effect of calcium in the diets of Northwestern Mexico directly in the general population taking into consideration factors that may play a role in maintaining bone structure such as exercise, age, sex.

Absorption↗

[Description, distribution, anatomy, chemical composition and uses of Mimosa tenuiflora(Fabaceae-Mimosoideae) in Mexico].

Because of some catastrophic events which occurred in Mexico during the 1980 decade, the utilization of "tepescohuite" bark against skin wounds and burns was popularized. The media manipulated the lack of available information about its medical properties and gave erroneous information to the society propagating a lot of myths. Therefore, the aim of this paper is to determine its taxonomic identity and to study the distribution, bark and wood anatomy of this species, and to determine its actual and historic uses, and the compilation of the information about bark pharmacology and toxicity. Its taxonomic identity is established as Mimosa tenuiflora (Willd.) Poir. (Fabaceae-Mimosoideae). It blooms and fructifies from November to June, occurring in Mexico (the states of Oaxaca and Chiapas), Guatemala, Honduras, El Salvador, Nicaragua, Panama, Colombia, Venezuela and Brazil, at altitudes of 0-1110 (-1520) m. In Mexico, it is found in dry forests, thorny thickets, Pinus and Pinus-Quercus forests, and in M. tenuiflora pure thickets, along roads and in resting or abandoned culture lands. This species has an aggregate distribution in the forests and a uniform one in the thickets. It presents a mean density of 9 individuals per m2, with 0.45 of frequency per quadrat and 1.69 m2 of mean coverture, and it has a wide range of tolerance to climatic and edaphic factors, confirming their invasive character. Regionally, the wood is used as fuel and fence construction, and against skin wounds and burns (bark tea, powder and/or ointment), and diverse products, such as shampoos, creams, capsules, soaps, etc., are commercialized. The bark is wrinkled, reddish-brown to grey, fibrous texture, 0.5-1.5 mm thick, resinous and with an astringent odor and flavor, and with a great quantity of tannins. The wood presents extremely short vessel elements, with alternate areolate punctuations, and simple perforated plates, vasicentric axial parenchima, confluent stripes, uniseriated rays, extremely short, fine and very short libriform fibres. The bark contains tannins, saponins, an alkaloide fraction, lipids, phytosterols, glucosides, xylose, rhamnose, arabinose, lupeol, methoxychalcones, and kukulkanins.

Mexico↗

[Dr Seweryn Gałezowski's professional examination in Mexico City in 1837].

On 6th and 7th January 1837 in Mexico City Dr Seweryn Gałezowski took his professional examination. As the result of the examination and other presented documentation Dr S. Gałezowski was awarded "titulo medico" which allowed practising the medical profession both in Mexico City and the whole country. The Polish writings do mention the examination (the date is missing) but it is interpreted not only inaccurately but to say the least diversely as M.D. dissertation. The analysis of documents and archives materials in the present work established that Seweryn Gałezowski never obtained a new doctorate in Mexico and it uncovers also some otherwise unknown so far biographical data concerning Gałezowski.

Accreditation↗

[Pierre Ochart, third printer in Mexico City and editor of the first medical book in America, Opera medicinalia, by Dr. Francisco Bravo, 1570].

The first medical book edited in the American Continent was printed by Pierre Ochart in Mexico City (1570). He was born in Normandy in the City of Rouen, France, and learned the profession of printer in Mexico City. We have done an examination of the book written by Francisco Bravo, a Spanish doctor in medicine who practiced in Mexico City since the XVIth century second half.

France↗

Differing postneonatal mortality rates of Mexican-American infants with United-States-born and Mexico-born mothers in Chicago.

OBJECTIVES: This study sought to determine the relationship between maternal nativity and the postneonatal mortality rate of urban Mexican-American infants. DESIGN: This is a population-based study. METHODS: Stratified and logistic regression analyses were performed on a data set of 1992-1995 computerized birth-death records of all Mexican-American infants born to Chicago residents with appended 1990 United States Census income and 1995 Chicago Department of Public Health data. RESULTS: In Chicago, Mexican-American infants (N = 10,599) of US-born mothers had a postneonatal mortality rate of 3.2/1,000 compared to 2.1/1,000 for infants (40,813) of Mexico-born mothers; relative risk (95% confidence interval) equaled 1.5 (1.0-2.3). The adjusted odds ratio of postneonatal mortality was 1.4 (1.1-1.9) for Mexican-American infants of US-born mothers. The mortality rate due to preventable causes (sudden infant death syndrome, homicides, non-intentional injuries, and infections) for Mexican-American infants of US-born mothers was twice that of infants of Mexico-born mothers; relative risk (95% confidence interval) equaled 2.2 (1.3-3.8); this nativity differential persisted in non-impoverished communities. CONCLUSION: The postneonatal mortality rate of urban Mexican-American infants with US-born mothers exceeds that of infants with Mexico-born mothers. This nativity disparity is attributable to preventable causes.

Acculturation↗

Postpartum IUDs in Mexico.

Dr. Ramon Aznar, head of the medical subdivision of the Mexican health insurance program (IMSS), reports that postpartum insertion of IUDs has met great success in Mexico. In 1983, the number of postpartum IUD acceptors in the family planning program of the IMSS reached 83,763, making it the most popular method of postpartum contraception there. The program emphasizes the need for adequate training of delivery room staff and for alerting women to possible contraceptives postpartum. FHI has conducted studies of postpartum IUD use worldwide, including Mexico before the programmatic use of the method. Mexico now has the largest experience of any country in postpartum insertion. The Mexican experience serves to validate the contention that postpartum IUD insertion, accomplished during 1 of the few times in many women's lives that they have contact with the health care system, can make a significant contribution to family planning in the developing world.

Americas↗

An examination of regional migration patterns in Mexico: new and old Mexican regions.

This paper examines Mexican regional patterns. Different regional definitions are utilized to examine in-/out-migration patterns in 4 different periods: 1) 1979-1980, 2) 1975-1979, 3) prior to 1975, and 4) lifetime. 5 regional definitions previously used to delineate state level Mexican regions were compared to new regions by a maximum likelihood clustering technique. Previously defined regions do not compare with the empirically delineated regions developed by the cluster analysis. A cluster analysis of in-/out-migration patterns suggests the following: 1) distinct in-/out-migration patterns for both short- and long-term migration patterns, 2) a central region consisting of Mexico and the Federal District having its own distinct regional characteristics for both in-/out-migration patterns, particularly intraregional migration among those 2 states exceeds any other interregional migration patterns, and 3) the unique role played by Jalisco in mediating long-term inflows prior to 1975, and since 1975, out-migration from the same state. Previous research rarely identified the Central region consisting of Mexico and the Federal District. Using net migration for interregional migration analysis may possibly be misleading since immigration and out-migration phenomena show distinct patterns of geographic mobility at the state level, and such regional differences are consistent for the 4 migration periods. A careful analysis accounting for both distinct migration patterns in the Central region and different patterns in in-/out-migration are necessary to obtain an understanding of regional migration patterns in Mexico.

Americas↗

[A new migratory horizon in Central Mexico: 1970-1990].

"During the last few decades migration in Central Mexico has undergone important changes. Not only have populations been moving increasingly towards the periphery and decreasingly towards the center, but those originally living in the center are also moving to the immediate periphery. This behavior allows us to claim that Central Mexico is undergoing a process of deconcentration or suburbanization. This study describes the way in which such a process has developed and the situation of geographical entities within that process. Analysis of the new regional configuration takes into account demographic growth and the direction and characteristics of migration in the Mexico City Metropolitan Area and its surrounding states during the last twenty years." (SUMMARY IN ENG)

Americas↗

[Shaping of the migratory process in northern Mexico, 1930-1990].

"During the third decade of this century Mexican geographical structure began to change notoriously. Due to the strong influence of [the] North American economy, the north of Mexico became progressively one of the most important regions in the country, with the emergence of favorable perspectives of economic growth. Soon it became attractive to migration from the demographically pressed regions of Central Mexico. Thus, the north of Mexico was favored by the presence of qualified workers and a growing population. However, the region was not evenly populated, due to geographic, historic, and socio-economic factors that...[affect] the processes of migration and settlement. Some regions present important changes in their migratory flow, evidenced by the presence of new entities of origin and the disappearance of others." (SUMMARY IN ENG)

Americas↗

[The geographical distribution of fertility around Mexico City].

A spatial analysis of fertility around Mexico City reveals an "inverted U" pattern which appears, on the face of it, inconsistent with both conventional economic location analysis and a spatial diffusion process. A closer examination of the problem implies that economic variables, when integrated in a proper model, may account for the observed cross- sectional spatial pattern, whereas pure diffusion can not. Spatial diffusion, however, may be responsible at least in part for the observed fertility changes over time. The geographical patterns of fertility in 2 states neighboring Mexico City (Mexico and Hidalgo) are examined empirically. The interpretation of the nonmonotonic distance effect is that there are significant locational advantages to childbearing at medium distances that are not enjoyed at households location either very close or far away from the city.

Americas↗

[Blood group frequencies and ABO and RhD incompatibilities in La Paz, Baja California Sur, Mexico].

OBJECTIVE: To determine genic and phenotypic frequencies and predict the risk of incompatibility and maternal alloimmunization in the population of La Paz. MATERIAL AND METHODS: This descriptive study evaluated 1809 voluntary blood donors attending in 1998 the Hospital General de Zona of Instituto Mexicano del Seguro Social (Zone General Hospital of the Mexican Institute of Social Security) in La Paz, Baja California Sur, Mexico. Blood donors were typified by tube agglutination. The gene frequencies were estimated assuming equilibrium conditions, and incompatibilities and alloimmunization were statistically assessed with the chi 2 test. RESULTS: Percent frequencies were as follows: blood group O, 58.49%; A, 31.40%; B, 8.40%; AB, 1.71%; RhD, 95.36%; and RhD negative, 4.64%. Genic frequencies were: i, 0.7648; IA, 0.1821; IB, 0.0519; D, 0.7845; and d, 0.2155, respectively. Incompatibilities between couples and mother-child were 0.3023 and 0.1685 for ABO, 0.0442 and 0.0364 for RhD, and 0.0134 and 0.0061 for double incompatibility, respectively. The probability of maternal alloimmunization was estimated at 0.0309. CONCLUSIONS: The O and RhD groups were the most common in La Paz, although frequencies were among the lowest in Mexico, contrary to the case of A and RhD negative groups. The probabilities of maternal alloimmunization and of incompatibilities were also high. Ancestral white, black, and indigenous groups admixed in the northwestern part of Mexico; after migrating to Baja California Sur the admixture of the population probably became similar to that of the remainder of the northwestern area.

ABO Blood-Group System↗