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PubMed1990

[Immunologic disorders in children with developmental thoracic defects].

As the result of immunological examination of 21 children with developmental defects of the chest and analysis of the course of the postoperative period in 136 children, among which 36 had hereditary syndromes of systemic connective-tissue dyshistogenesis, it was found that suppurative complications of thoracoplasty, which are encountered in 15% of children with isolated developmental chest defects and in 33.3% of those with the above mentioned syndromes, were caused to a great measure by disorders of the immune status. The most serious immunological deviations were encountered in the Marfan syndrome due to impaired phagocytic activity of neutrophils and monocytes, decreased number of T, T active, and B lymphocytes, and diminished function of T helpers. In unclassified complexes of developmental defects with Marfaneic ++ phenotypes, the immunological disorders were similar, but less deep. In the Ehlers-Danlos syndrome, a decrease of the number of immunocompetent cells, function of T helpers, and neutrophils was mainly revealed. In isolated forms of funnel chest the function of monocytes and the number of immunoglobulins are mainly decreased.

Adolescent↗
PubMed1984

[Surgical treatment of deformities of the anterior thoracic wall by frontal chondrotomy: an original technic].

According to the author, the frequency of recurrence after sternochondroplasty is related to the poor quality of the chondral callus which is of limited thickness. In addition, it is subjected to shearing force at each respiratory movement. The author proposes frontal chondrotomies allowing anterior displacement in funnel chests or posterior cartilages are sutured. The correction obtained is stable without any supplementary fixation. The plane of section being perpendicular to respiratory movement, the sutures are no longer submitted to shearing strain but to alternate compression and traction. In this way secondary displacement is avoided.

Biomechanical Phenomena↗
PubMed1985

Moyamoya disease with a developmental anomaly of the mesenchyme.

We treated a Japanese boy with moyamoya disease accompanied by synbrachydactylia, funnel chest, pes equinus and short stature. Angiograms showed the anomalous origin of the occipital artery in addition to the moyamoya vascular network at the base of the brain. A generalised mesenchymal anomaly was suggested in this case.

Abnormalities, Multiple↗
PubMed1952

Advances in pediatric surgery.

Recent advances in pediatric surgery have been made in several fields. Hydrocephalus is again being treated by draining the cerebrospinal fluid into either the ureter, the mastoid antrum or the peritoneal cavity. Funnel chest should be corrected surgically. Congenital atresia of the esophagus is best treated by a one-stage operative repair. Patent ductus should be closed. Operations are available for cyanotic children. Intussusception is again being treated by barium enema in selected cases. Megacolon can be benefited by surgical procedures, which now are directed at the distal spastic segment rather than the proximal dilated segment.

Child↗
PubMed1988

Subcutaneous silicone implants in pectus excavatum.

In seventeen patients presenting funnel chest a subcutaneous implantation of silicone prostheses was performed. In nine patients seromas were aspirated postoperatively. Five patients were reoperated, one for correction of a displacement of the prosthesis, one for size reduction and one for implant removal, because of various complaints not related to the prosthesis. At the final evaluation sixteen out of seventeen patients expressed satisfaction with the result.

Adolescent↗
PubMed2006

Modified Nuss operation for pectus excavatum: design for decreasing cardiopulmonary complications.

BACKGROUND: Thoracoscopic Nuss operation of funnel chest is increasingly performed. However, it has a high rate of complications. This study developed some modifications to facilitate Nuss operations with the intention of reducing several major complications. METHODS: Patients who presented for surgical repair of pectus excavatum from July 2003 through June 2004 had a preoperative computed tomography (CT) scan, pulmonary function tests, and cardiac echo before and two months after the modified Nuss operation. The following modifications of the standard Nuss procedure were implemented: (1) One small subxyphoid incision was made to guide the plate implantation and to decrease cardiopulmonary complications. (2) Thoracic muscles were dissected off the ribs to provide muscle pockets. (3) Shorter thick stainless-steel AO bars were selected to avoid thoracic outlet syndrome and restriction. (4) The bars were fixed to adjacent ribs by 4-0 stainless steel wires into the submuscular pockets. (5) No thoracoscope routinely used. (6) No chest tubes were placed to decrease chest pain or for cosmetic purposes. RESULTS: 15 patients aged between 4 and 32 years (mean, 18.6 +/- 7.8) underwent evaluation. Preoperative CT index was 4.14 +/- 0.86. The average operating time was 95.7 +/- 27.0 min. There was no bar dislocation, prolonged pain, or neuralgia. Echocardiography showed no pericarditis and no pneumothorax occurred after placement of the intrathoracic bar. CONCLUSION: A small subxiphoid incision makes bar implantation easier and has reduced the incidence of major complications in this early experience with 15 patients.

Adolescent↗
PubMed2005

[Treatment laryngomalacia: experience with 22 cases].

UNLABELLED: Laryngomalacia is the most frequent cause of stridor in childhood, and in most of the cases, spontaneous resolution occurs by the age of 2 years. Approximately 10% of the cases (severe laryngomalacia) require surgery. This condition is of unknown etiology and its diagnosis is made by fiberoptic laryngoscopy, which shows shortening of the aryepiglottic folds, and/or redundant arytenoid mucosa, and/or anterior-posterior epiglottic prolapse. AIM: Our objective was to verify the main clinical and anatomical affections and to highlight the clinical parameters for clinical follow-up and surgical indication in patients with laryngomalacia. STUDY DESIGN: Transversal cohort study. MATERIAL AND METHOD: Twenty-two children diagnosed with laryngomalacia in the Pediatric Otorhinolaryngology of UNIFESP-EPM, from January 2001 to December 2003, whose clinical and surgical follow-up were performed by the same examiner, were enrolled in this study. RESULTS: Out of twenty-two evaluated children, 2 (9.1%) presented with severe laryngomalacia and pectus excavatum (funnel chest). At polysomnography, no child presented any significant respiratory event during sleeping. Those two children with severe laryngomalacia were submitted to supraglottoplasty with resection of the aryepiglottic folds. CONCLUSION: We concluded that stridor and shortening of the aryepiglottic folds are preponderant in children with laryngomalacia. The polysomnographic exam did not prove to be a good parameter for clinical follow-up, neither for surgical indication. The most important parameters were pectus excavatum and failure to thrive. Supraglottoplasty is effective with low rate of morbidity.

Cohort Studies↗
PubMed1997

[A simultaneous operation of aortic root, arch replacement, and sternal elevation for Marfan's syndrome--a case report].

A 42-year-old male was transferred to our institution by his family doctor because of suspected type A aortic dissection with cardiac tamponade. His physical constitution gave the appearance of Marfan's syndrome. Contrast CT revealed DeBaky type 1 aortic dissection. Angiography detected an Annulo-aortic ectasia complicated by an aortic regurgitation (AR) grade IV. He also suffered from a severe funnel chest. We performed simultaneous procedures of aortic root, arch replacement, and sternal elevation. Upon operation, a staged aortic clamp technique was employed to reduce the period of cardiac arrest. In the sternal elevation, the bilateral internal thoracic arteries were preserved. Post operative course was uneventful. We consider it effective to employ the staged aortic clamp technique in a reconstruction of the entire thoracic aorta in the case of poor cardiac function and to preserve the bilateral internal thoracic arteries in sternal elevation in order to prevent infection.

Adult↗
PubMed1976

The surgical treatment of pectus excavatum: an experience with 90 operations.

Funnel chest, a congenital hereditary deformity, may lead to impairment of cardiopulmonary function. The predominant motives for operation are psychological and cosmetic. Patients with minor deformities amenable to physiotherapy should not be operated upon, but moderately severe defects justify surgical intervention. Objective photographic documentation is essential. Because of their importance to surgical technique and results, the symmetrical, asymmetrical, localized, and extensive deformities should be distinguished. Ninety operations were performed between 1951 and 1974 according to the various techniques known during that period. Results were irregular until the introduction eight years ago of an operation combining extensive resection according to Ravitch and stabilization by a metal strut as recommended by Adkins and others. Of 24 operations performed during the last eight years, 23 have given excellent long-term results.

Adult↗
PubMedDate not supplied

Penetration of ampicillin and sulbactam into human costal cartilage.

The question of whether ampicillin and sulbactam are able to penetrate sufficiently into costal cartilage tissue was investigated in 21 children undergoing surgery for funnel chest malformations. The concentrations of both compounds were determined in the core and mantle pieces of samples taken 45 min or 120 min after infusion of ampicillin/sulbactam (33.3/16.7 mg/kg bodyweight) preoperatively for antibiotic prophylaxis. Ampicillin was determined by bioassay and sulbactam was determined by gas-chromatography/mass spectrometry. Mean concentrations of ampicillin were 23.3 mg/kg and 10.4 mg/kg at 45 min and at 27.4 mg/kg and 7.8 mg/kg 120 min in the mantle and core piece, respectively. Mean concentrations of sulbactam were at the same time 21.3 mg/kg and 9.7 mg/kg and 17.5 mg/kg and 11.9 mg/kg, respectively. These values indicate that both compounds achieve high concentrations even in bradytrophic tissue such as cartilage. The concentrations exceed the MIC values of important bacterial pathogens involved in postoperative wound infections. Therefore ampicillin protected by sulbactam appears to be a well-suited agent for perioperative prophylaxis in thoracic surgery.

Adolescent↗
PubMed2005

[Lumbar epidural morphine for postoperative analgesia in children undergoing Nuss procedure].

BACKGROUND: We examined the effects of lumbar epidural morphine for postoperative analgesia in children after the Nuss procedure for funnel chest. METHODS: An epidural catheter was inserted from the L 3-4 interspace preoperatively (epidural group). Epidural morphine 30 microg x kg(-1) was given at the beginning of the operation. Postoperatively, epidural morphine 3 microg x kg(-1) x hr(-1) was infused. The frequency of demand for postoperative analgesia was retrospectively compared with that of children who had not received epidural morphine (control group). RESULTS: On the 0th postoperative day, the epidural group required fewer analgesics than the control group (0.50+/-0.30 vs. 2.50+/-1.00 x day(-1)). However, after the 1st postoperative day, the demand for analgesia did not differ between the two groups. CONCLUSIONS: Epidural morphine 30 microg x kg(-1) given at the beginning of operation provided effective analgesia on the 0th postoperative day after the Nuss procedure. However, epidural infusion of morphine 3 microg x kg(-1) x hr(-1) was not effective after the 1st postoperative day. Further study is needed to determine the lumbar epidural infusion dose of morphine adequate for use after the Nuss procedure.

Analgesia, Epidural↗
PubMed2006

Minimally invasive correction of pectus excavatum in adult patients.

OBJECTIVE: The repair of pectus excavatum by minimally invasive surgery (Nuss procedure) is well established among pediatric surgeons. Studies on adult patients are rare. We analyzed the efficacy of minimally invasive pectus repair in a series of adult patients. METHODS: We prospectively included all adult patients with minimally invasive repair of funnel chest treated from 2000 to 2005. The pectus bar was inserted under thoracoscopic control. On the right side a stabilizer was used to prevent bar displacement. Postoperative pain control was provided by epidural catheters. Clinical checks were performed 2 weeks, 3 months, and then annually after discharge. RESULTS: Forty-three adult patients (39 men, 4 women) with a mean age of 22 years (range 18-39 years) were included. Mean duration of the operative procedures was 70 minutes (range 29-125 minutes); mean length of hospital stay was 9.3 days. Bars were removed from 15 patients 3 years after implantation. Minor complications occurred in 8 patients (19%), with intrapleural effusions being most frequent (n = 5). Three patients (7%) had major complications: drainage of a pneumothorax (n = 2) and bar displacement (n = 1). The cosmetic results were excellent and patient satisfaction was high. CONCLUSIONS: We conclude that the Nuss procedure was beneficial in adult patients. Dislocation of the pectus bar can be prevented by submuscular placement. The use of corticosteroids may be helpful in case of repeated, uncontaminated pleural effusions. Patient satisfaction and the acceptable number and kind of complications are encouraging.

Adolescent↗
PubMed2002

Submuscular bar, multiple pericostal bar fixation, bilateral thoracoscopy: A modified Nuss repair in adolescents.

BACKGROUND/PURPOSE: Thoracoscopic Nuss repair of funnel chests is used increasingly, but has a high bar dislocation rate. The authors intended to reduce this by technical modifications of the original Nuss technique. METHODS: In 40 patients from 12.3 to 42.1 years of age (mean, 17.6 +/- 5.8) the bars were placed directly on the ribs in a submuscular position and fixed by a minimum of 14 absorbable figure of 8 sutures around the bar and the underlying rib placed under bilateral thoracoscopy. Two stabilizers were used in all patients, the bar was introduced from the left in severe cases, and a second bar was implanted in most beyond 16 years of age. All patients underwent follow-up to date in a prospective observation study. RESULTS: There was no bar or stabilizer dislocation, no prolonged pain or neuralgia, but one traumatic seroma, one pleural, and one pericardial effusion. One bar was easily removed after 13 months. CONCLUSIONS: Submuscular position provides a far better bar fixation and soft tissue coverage of Nuss implants. The technique is technically more demanding but safe and has reduced the incidence of bar dislocation to zero in this early experience of 40 adolescent patients, although no sportive restrictions were imposed on the patients at all.

Adolescent↗
PubMed1985

[Surgical treatment of flail chest by sliding staples].

The authors have compared the results obtained in two series of patients with flail chests treated by internal fixation. In the first series of 36 patients, Judet rib staples were used. The average time of artificial ventilation was 5.8 days. In the second series of 43 patients, gliding staples were used. The average time of artificial ventilation was only 2.6 days, a significant reduction. Thanks to this new technique, the indications for artificial ventilation in the treatment of flail chests have been reduced from 47 per cent to 33 per cent. The technique of fixation has also been used in seven cases of operative treatment of funnel chests. In five other cases it has been used to reinforce plastic mesh inserted after extensive resection for malignant tumour.

Adolescent↗
PubMed1988

[Mitral valve prolapse: two-dimensional echocardiographic screening in apparently healthy students].

To elucidate the clinical features of mitral valve prolapse in apparently healthy young population, two-dimensional echocardiography was performed in the students (18-22 years) without documented organic heart diseases. Focusing on the systolic dislocation and configuration of the anterior mitral leaflet, a following two-dimensional echocardiographic criterion for grading prolapse was used: Grade I: subjects only with slight slip of the tip of the anterior mitral leaflet (AML) toward the left atrium, Grade II: those with considerable slip of the AML but keeping a normal convex shape in the leaflet body toward the left atrium, and Grade III: those with severe slip of the AML with its ballooning toward the left atrium. Among 2016 students examined, 1507 subjects (74.8%) were judged to be normal, 343 (17.0%) to be Grade I, 141 (7.0%) to be Grade II, and 25 (1.2%) to be Grade III. Of the 25 subjects in Grade III, 20 subjects underwent further examination including a questionnaire about the subjective complaints, physical examination, electrocardiograms at rest and during exercise, Doppler echocardiography and postural tests. Concerning the subjective symptoms, eight subjects had some complaints including chest pain, shortness of breath, dizziness, palpitation, fatigability and synocope, and four of the eight had more than three complaints. Mid-systolic click and a late systolic murmur were audible in four and funnel chest was observed in one. No specific findings were found by electrocardiograms. Mild mitral and tricuspid regurgitations were observed by Doppler echocardiography in four and nine subjects, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMedDate not supplied

The ribs: anatomic and radiologic considerations.

The ribs are essential structures of the osseous thorax and provide information that aids in the interpretation of radiologic images. Techniques for making precise identification of the ribs are useful in detection of rib lesions and localization of lung lesions. The big rib sign and the vertical displacement sign can be used to differentiate the right and left ribs on lateral chest radiographs. The clavicle, the xiphoid process, and the sternal angle may be used as anatomic landmarks for rib counting on computed tomographic scans. For rib counting on lateral chest radiographs, the sternal angle or the 12th rib may be used. Anatomic rib variants include developmental deformities, cervical rib, and short rib and may mimic true rib diseases. Detection of thoracic deformities such as funnel chest (pectus excavatum) and barrel-shaped thorax requires an awareness of the strong correlation between the transverse appearance of the thorax and costal shape. Shadows around the rib cage (eg, rib companion shadows, sharp lines along the lower margin of the ribs, rib overlying shadows) may mimic pleural and extrapleural disease on frontal chest radiographs. It is imperative that the radiologist be familiar with normal rib anatomy, normal rib variants, and the radiologic appearance of the ribs to prevent misdiagnosis.

Humans↗
PubMed1991

An approach to the management of chest wall deformities.

Chest wall deformities are seen frequently in children and adolescents. Fortunately, the deformity is usually mild and the only therapeutic requirement is patient and family reassurance. If the deformity is more severe, consideration must be given to surgical correction. Although sophisticated studies have shown that cardiopulmonary function may be limited by funnel chest, the findings are rarely of clinical significance and, therefore, with few exceptions, operations will be performed for cosmetic and/or psychological reasons. In order to be able to manage patients with chest wall deformities appropriately, clarity of thinking is essential in relation to classification, symptomatology and treatment options. Before reaching a final decision regarding operation, several interviews may be required. In order to assess the final result, long-term follow-up is mandatory.

Adolescent↗