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At least 523 records · Page 29Linked to original sources
PubMed1995

[Surgical treatment of obstructive sleep apnea by osteotomy of the facial bones (results of 1 year)].

Surgical treatment of obstructive sleep apnea with abolition of obstructive apneas and hypopneas is possible by maxillomandibular advancement as our own results in 24 patients show. Maxilla and mandible must be advanced at least about 10 mm to secure success. Indication for maxillomandibular advancement should be restricted to patients with certain craniofacial disorders, which are of retrognathic dolichofacial type combined with pharyngeal narrowing. Before considering surgical treatment other possible contributing factors as for instance obesity should be eliminated, the more as nCPAP-therapy constitutes an effective conservative method. Despite our unchanged success rate after 1 year further polysomnographic follow-up control is essential to see what happens 5, 10 or 20 years after maxillomandibular advancement.

Adult↗
PubMed1996

[Principles of surgical treatment of obstructive sleep apnea by interventions on the facial bones].

The clinical picture of the obstructive sleep apnea syndrome is caused by a multifactorial etiology. Therefore a lot of different conservative as well as surgical therapeutic approaches are discussed. In approximately 40% of the patients an obstruction of the pharyngeal airway is combined with an abnormal sagittal morphology of the skull. In these cases a simultaneous maxillomandibular advancement by at least 10 mm seems to be a causal therapy, leading to an enlargement of the pharyngeal airways. The current therapeutic results are roughly stable up to a period of approximately 3 years. Requirement of this therapy is the exclusion and/or the prior therapy of an extreme obesity, which can favour the manifestation of an obstructive sleep apnea syndrome.

Airway Obstruction↗
PubMed1992

Reconstruction of bone on facial surfaces: a series of case reports.

To rebuild the damaged periodontium to its original form, it would be ideal not only to cover the denuded root surfaces with soft tissue, but also to reconstruct the cortical plate. This paper presents four cases in which osseous grafts and guided tissue regeneration, along with root surface conditioning, were used to encourage growth of new facial bone. Some degree of success was achieved in each case.

Alveolar Bone Loss↗
PubMed1996

[The use of tactivin in the combined treatment and prevention of complications in reconstructive operations on the bones of the facial skeleton].

Sixty-three patients with congenital and acquired defects and deformations of facial bones without concomitant diseases were examined. Twenty-eight of them were operated on; auto- and alloplasty was resorted to in 18 patients, and to 10 patients tactivin was administered after common protocols for immunocorrection before or after surgery. Immunologic and clinical studies showed that immunodeficiency states are the most probable causes of postoperative complications following repair surgery on the facial bones. Tactivin normalized the immunity parameters and prevented the development of postoperative complications.

Adjuvants, Immunologic↗
PubMed1983

Panostotic fibrous dysplasia: a congenital disorder of bone with unusual facial appearance, bone fragility, hyperphosphatasemia, and hypophosphatemia.

We report a boy with unusual facial appearance, melanotic patches ("coast-of-Maine" type), myelofibrosis, recurrent femoral fractures, and widespread fibrous dysplasia of bone. Biochemical findings included raised serum alkaline phosphatase (bone isozyme) and 1,25-(OH)2 vitamin D, and low serum phosphorus levels. Elevated urinary excretion rates of total hydroxyproline, glycylproline, and gamma-carboxyglutamic acid indicated increased turnover of bone matrix. Transiliac bone biopsy showed a dearth of marrow elements, greatly increased bone turnover, and absence of normal trabecular organization. Serial radiographs showed progressive cortical thinning and loss of bony trabeculae. Calcitonin and etidronate treatments had no lasting effect on the progressive bone disease. The term "panostotic fibrous dysplasia" is suggested for this condition.

Alkaline Phosphatase↗
PubMed2005

Expression and mechanical modulation of matrix metalloproteinase-1 and -2 genes in facial and cranial sutures.

Craniofacial sutures create a soft tissue interface between various calvarial and facial bones. Facial and cranial sutures show differences in their surrounding anatomical structures and local mechanical strain environments. Despite previous attempts to identify the expression of matrix metalloproteinase genes (MMPs) in cranial sutures, little is known regarding whether facial and cranial sutures differ in MMP expression. We have investigated the expression of MMP-1 and MMP-2 in the pre-maxillomaxillary suture (PMS; facial suture) and the frontoparietal suture (FPS; cranial suture) in 32-day-old rats with or without the application of cyclic loading. Expression of MMP-1 and MMP-2 was detected by the reverse transcription/polymerase chain reaction technique. At 32 days of postnatal development (n=6), both MMP-1 and MMP-2 were reproducibly expressed in the facial PMS, in comparison with negligible MMP-1 and MMP-2 expression in the cranial FPS. In six age- and sex-matched control rats, cyclic loading at 4 Hz and 1000 mN was applied to the maxilla for two 20-min episodes within a 12-h interval. In some (but not all) cases, cyclic loading induced marked expression of MMP-1 and MMP-2 in the PMS and FPS in comparison with corresponding non-loaded controls. These data confirm our previous finding that short doses of cyclic loading upregulate MMP-2 expression in craniofacial sutures and suggest the possibility that facial and cranial sutures differ in matrix degradation rates during postnatal development.

Animals↗
PubMed2001

[Pneumatization of the mastoid process in medieval and contemporary skulls in light of radiologic and anthropometric measurements].

Pneumatization and morphogenesis of the temporal mastoid process take place concurrently and exhibit noticeable variability. The mastoid process is phylogenetically the youngest part of the skull. The aim of this work was to examine the pneumatization of the mastoid process in mediaeval and contemporary skulls using radiological and anthropometric methods. 85 male skulls from the second half of the 20th century were compared with 102 male and 50 female skulls from the Middle Ages. Bilateral X-ray images of mastoid processes according to Schuller were obtained and anthropometric measurements were done. Planimetry was used to obtain the air cell area of the mastoid processes. Correlations between several parameters of the temporal bone, facial bones, cranial bones and pneumatization of the mastoid process were studied. X-ray images revealed four types of the mastoid process: pneumatic, mixed, sclerotic, and apneumatic. The pneumatic mastoid process prevailed in every group of skulls. The mixed type was the least frequent in mediaeval female skulls and most frequent in contemporary male skulls. The apneumatic type was the rarest one in all groups of skulls. The largest surface area of mastoid air cell system was found in contemporary male and the smallest in mediaeval female skulls (Fig. 5). An asymmetry between left and right processes was observed in mediaeval and contemporary skulls, being more evident in the latter. No correlation was found between anthropometric parameters of the skull and the extent of pneumatization of the mastoid process.

Adult↗
PubMed1995

Orofacial manifestations of child abuse and neglect.

About one-half of all child abuse cases involve some form of orofacial injury. Common signs of physical abuse include fractures of the teeth or the maxilla, mandible and other facial bones, facial burns, lacerations of the lips and lingual frenum, and bite marks on the face and neck. Sexual abuse should be suspected if erythematous, ulcerative, vesiculopustular, pseudomembranous and condylomatous lesions are present on the lips, tongue, palate, face or pharynx. Dental neglect, a common form of child maltreatment, should be suspected if rampant caries and oral infection, bleeding and trauma persist despite the elimination of financial and transportation obstacles. Questioning the child and parents separately may help uncover an obvious discrepancy between the clinical findings and the history. Reporting suspected child abuse to the appropriate agency may protect the child from further injury and help the family obtain assistance to correct abusive practices and minimize the recurrence of abuse.

Child↗
PubMed1986

[Incidence of bone tumors in the facial skeletal area].

Facial bone tumors seen at a specialized referral unit over the course of a decade were retrospectively reviewed. Case definitions and statistical analysis were performed in accord with the criteria established by the National Bone Tumor Registry. Two-thirds of the 110 histologically confirmed bone tumors of this region occurred in female patients. The average age at onset was 39 years. Tumor-like processes predominated (56.4%). Peripheral giant cell granulomas were the most frequent lesions followed by odontogenic tumors (19%), principally odontomas. Benign bone tumors contributed 15.4%. The least frequently represented types of facial bone tumors were primary and secondary malignancies.

Adolescent↗