Comparison methods of examination in acquired color vision deficiencies.
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Studies of spectral electroretinograms in central serous retinopathy (CSR) and hereditary macular degeneration (HMD) showed that the b-wave amplitudes of most wavelengths of CSR were significantly decreased as compared with normal controls, and those of HMD were obviously lower than the normal values. Patients of HMD with type-A color vision defects (CVD) had primarily a reduction of b-wave amplitudes in the full spectrum of 480-620 nm, and patients with type-I CVD a reduction of b-wave amplitudes wave-lengths of 480-560 nm. These differences might reflect differences in damages to the medium-and long-wave length.
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Studies of spectral electroretinograms in central serous chorioretinopathy (CSC) and hereditary macular degeneration (HMD) found that the b-wave amplitudes of CSC for most wavelengths were significantly decreased as compared with normal controls, and the b-wave amplitudes of HMD for most wavelengths were obviously lower than the normal values. Patients of HMD with type-A color vision defects (CVD) showed primarily a reduction of b-wave amplitudes for the full spectrum of 480-620 nm, and patients with type-I CVD a reduction of b-wave amplitudes for wavelengths of 480-560 nm. These differences might reflect differences in damages to the medium-and long-wave length cones.
The objective of this project was to evaluate an alternative procedure for administering reflective-type color vision tests. In this procedure, the tests are illuminated by a low color-temperature, 100 W, incandescent lamp (i.e. an improper illuminant) and the patient then views the illuminated test elements through an inexpensive gelatin filter placed before his eye (e.g. a Wratten 78AA costing about $4). Since the relative transmittance of this filter is quite similar to that used in the Macbeth Easel Lamp, the tests should still be valid. In fact, this alternative procedure yields test performances for normal and deficient subjects on the 100-hue, panel D-15, and AO H-R-R tests that are virtually identical to those obtained using a standard Macbeth Easel Lamp.
A field study was conducted among 21 male workers exposed to styrene of concentration below 30 ppm in a fiber-reinforced plastic boat manufacturing plant. Twenty-one male workers with similar age groupings, years of education, and social and occupational state served as referents. The mean end-of-shift urinary mandelic acid (MA) and phenylglycoxylic acid (PGA) for the exposed workers were 84 mg/g creatinine and 66 mg/g creatinine, respectively. The Lanthony D-15 Hue Desaturated Panel was used to evaluate color discrimination of the exposed and referent groups. The results of the test were expressed as total color difference score (TCDS). The exposed workers' mean TCDS (a higher score denotes poorer color discrimination ability) was significantly (p < 0.0006) higher than the referents'. Neurobehavioral tests were also conducted, using the World Health Organization's Neurobehavioral Core Test Battery (NCTB). All the results of the NCTB were poorer for the exposed than for the referents. However, significant differences were observed only for Digit Span, Digit Symbol, and Benton Visual Retention tests. These results suggest that low exposure to styrene could affect some psychometric performance and may impair color vision.
We used the Farnsworth-Munsell 100 Hue Test to study the incidence of acquired color vision defects in 16 patients with unilateral and and seven patients with bilateral retrobulbar optic neuritis whose visual acuity had recovered to 6/12 (20/40) or better. We recorded the visual-evoked response to a pattern stimulus on the same day. All 30 affected eyes showed an excessive number of errors on Farnsworth-Munsell 100 Hue testing. The number of errors increased with greater residual optic nerve damage. One false-positive and two false-negative visual-evoked responses were found.
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