Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Tuberculosis, Spinal”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 505 records · Page 28Linked to original sources
PubMed1998

[Bone and joint tuberculosis in the field of orthopedics].

In Japan the number of patients with bone and joint tuberculosis has been dramatically decreasing since the beginning of 1980's. The number of patients was 1626 in 1978 according to statistics of tuberculosis patient in Japan. This was only 2.02% of new tuberculosis patients of Japan in 1978. Since that time the number of patients with bone and joint tuberculosis, in Japan, has been in steady decline. The number was only 675 patients in 1996. This was only 1.34% of new tuberculosis patients. The rate of new infections also decreased. Recently due to the development of computed tomography, magnetic resonance imaging and so on, patients with bone and joint tuberculosis can be diagnosed early, with great certainty. Curettage of infected focus and bone grafting via anterior approach has resulted in consistently improved results. While there are many reports of about the operative treatment with spinal instruments for spinal tuberculosis, artificial materials must be implanted with great care.

Humans↗
PubMed1990

Clinicosocial aspect of osteo-articular tuberculosis.

The study constituted clinicosocial analysis of 194 cases of osteo-articular tuberculosis. The disease was common in 1st and 2nd decades of life but not rare in old age with male preponderance. Majority of the patients were from rural area belonging to lower economic classes. Lesions were usually solitary (96.4%) situated in the weight bearing bones and joints (88.66%). Spinal tuberculosis was commonest (48.97%). The onset of disease was insidious in 94.8% cases. Chronic pain, swelling, impaired movements, deformities, sinus and cold abscess were found to be salient features of disease. Negligence and secondary infection were common.

Adolescent↗
PubMed1985

Spinal brucellosis.

Twenty-one patients with spinal brucellosis were reviewed. The disease is difficult to diagnose, and is often confused with spinal tuberculosis. Our study showed that it was best diagnosed by serology and bacterial culture; radiography and scanning were less helpful in the early stages. After only six weeks' antibiotic treatment, there was a 55% clinical and serological reactivation rate: better results were achieved after at least three months of treatment. The adequacy of treatment was best monitored with repeated agglutination titres, and the duration of treatment proved to be more important than the antibiotic agent itself. Surgical intervention was reserved for biopsy, severe neurological impairment, or for spinal stabilisation.

Adult↗
PubMed1992

[A case of miliary tuberculosis and chest wall cold tuberculous abscess with contents draining into the epidural space].

A 37-year-old man was admitted because of miliary tuberculosis. However, his fever and general condition did not improve with chemotherapy. Six months later, paraplegia occurred following sudden radicular back pain without any alteration of segmental sensation. There were no abnormal findings on X-ray films of the thoracic and lumbar vertebrae. Examination by magnetic resonance imaging revealed that the contents of a cold tuberculous abscess in the right chest wall had drained into the epidural space through the intervertebral foramen. Drainage of the chest wall abscess and laminectomy were performed. Further investigation showed that this case did not belong to the usual type of atypical spinal tuberculosis reported previously.

Abscess↗
PubMed2006

[New type spinal osteotomy with cage inserting anteriorly and closing posteriorly to correct thoracolumbar kyphosis by a single posterior approach].

OBJECTIVE: To evaluate the feasibility, safety and efficacy of surgical correction of thoracolumbar kyphosis, using the new type spinal osteotomy with cage inserting into the intervertebral gap anteriorly and closing posteriorly by a single posterior approach. METHODS: Since 2003, eight consecutive patients with thoracolumbar kyphosis were treated surgically. There were 4 male and 4 female with the mean age of 35 years old (from 14 to 58 years old). There were 3 cases of congenital kyphosis with scoliosis, 1 case of old spinal tuberculosis kyphosis, 2 cases of post-traumatic kyphosis, 1 case of ankylosing spondylitic kyphosis with old stress fracture and 1 case of iatrogenic kyphosis post-op of laminectomy due to the removal of ependymoma from cauda equina. The apex level of kyphosis was T(11) in 1 case, T(12) in 2 cases, L(1) in 3 cases and L(2) in 2 cases. The average preoperative Cobb angle of kyphosis was 73 degrees (range from 42 degrees to 90 degrees), there were 3 cases associated with scoliosis, with the mean preoperative Cobb angle of scoliosis was 25.7 degrees (range from 20 degrees to 36 degrees). According to the Frankel grading system, 2 cases were classified as Grade C, 2 cases as Grading D and 4 cases as Grading E preoperatively. All the patients had severe thoracolumbar dorsum pain with difficulty of sitting. The bladder sphincter function disturbance were also found in 3 cases. The main procedures of the new type spinal osteotomy consisted of temporary rod installation, trans-intervertebral spinal osteotomy, circumferential decompression of the spinal cord, dissection and complete cut of the anterior longitudinal ligament, spreading the intervertebral gap with the distraction forceps during the instrumentation correction maneuver and replaced by the cage filled with autograft bone inserting into the intervertebral gap, then the closing maneuver followed. RESULTS: The average operation time was 4.5h (range from 3.5 to 6 h), and the mean blood loss volume during the operation was 2280 ml (range from 700 to 4200 ml). All patients underwent surgery safely and there were no major complications related to the surgical procedures, apart from CSF leakage of 1 case postoperatively and transient low blood pressure of 1 case intraoperatively. Localized kyphosis, scoliosis were reduced from an average of 73 degrees to 8.3 degrees and 25.7 degrees to 18.7 degrees respectively with an average 12.8 months follow-up. Bony fusion were achieved in all patients and there was no correction loss. Neurologic improvement occurred in 1 case from Frankel Grade C to Grade D, and 1 case from Frankel Grade D to Grade E after the surgery. The bladder sphincter function were also found improved in 2 cases postoperatively. CONCLUSIONS: The new type spinal osteotomy with cage inserting anteriorly and closing posteriorly by a single posterior approach was a safe, reliable and effective surgical procedure for the treatment of the thoracolumbar kyphosis with the Cobb angle from 40 degrees to 90 degrees. Compared with the other common spinal wedge osteotomies, the deformation danger, such as hanging down, kinking or dural buckling could be effectively prevented, a better correction rate is also achieved significantly with this new type procedure.

Adolescent↗
PubMed2005

Adherence and biofilm formation of Staphylococcus epidermidis and Mycobacterium tuberculosis on various spinal implants.

STUDY DESIGN: Bacterial adherence and biofilm formation in implant-associated infection may vary depending on species of microorganisms and characteristics of implant surfaces. OBJECTIVES: We evaluated the differences in adherence and biofilm formation between Staphylococcus epidermidis and Mycobacterium tuberculosis on various spinal implant surfaces. SUMMARY OF BACKGROUND DATA: In implant-associated infections, bacteria in biofilm are resistant to antibiotics or host defense mechanism. The removal of implants is usually necessary to eradicate infection. On the contrary, in tuberculous infection, complete debridement and antituberculous chemotherapy without removal of implant have been regarded as a safe procedure. METHODS: S. epidermidis and M. tuberculosis were cultured with 4 types of metal segments, smooth or rough-surfaced stainless steel, and titanium alloy, respectively. After isolation of colonized microorganisms and biofilm with trypsin treatment and culture on plate media, colony-forming units were counted. The features of adherence and biofilm formation were observed under scanning electron microscopy. RESULTS: Biofilm-forming S. epidermidis showed heavy adhesion and multiplication on the surface of all 4 metal segments, 16.5 times more colony-forming units than nonbiofilm-forming ones. On scanning electron microscopy, there were many aggregated microcolonies with thick biofilm in biofilm-forming S. epidermidis but much less in nonbiofilm-forming S. epidermidis. M. tuberculosis were rarely adhered to metal surfaces and showed scanty biofilm formation. CONCLUSIONS: On the contrary to S. epidermidis, adherence and biofilm formation of M. tuberculosis on implant surface are less likely, and it can provide the basis of successful instrumentation in spine tuberculosis.

Alloys↗
PubMedDate not supplied

Psoas abscess secondary to tuberculous lymphadenopathy: case report.

Tuberculous psoas abscesses, a well-known sequel of tuberculous spondylitis, very rarely develop without concomitant spinal involvement. We report a unique case where a psoas abscess was secondary to retroperitoneal tuberculous lymphadenopathy in a 13-year-old boy who had no demonstrable findings of spinal tuberculosis. Computed tomography showed an obvious communication between the necrotic and calcified retroperitoneal lymph node and the psoas abscess. To the best of our knowledge, fistulization of tuberculous lymph nodes into the psoas sheath has not been reported in the English-language literature.

Adolescent↗
PubMed2005

Mycobacterial osteomyelitis and arthritis.

Physicians can expect to see more mycobacterial bone and joint disease in North America as a result of increased travel, immigration, and use of immunosuppressive medications. The first step in treating infections caused by these organisms is to consider the diagnosis early in the course of illness. Long-standing untreated mycobacterial infections typically cause significant bone destruction and loss of function. The treatment of mycobacterial bone and joint infection requires prolonged antibiotic therapy, often in conjunction with surgical intervention, particularly for spinal tuberculosis.

Adrenal Cortex Hormones↗
PubMed1985

[Role of computed tomography in extrapulmonary tuberculosis].

A retrospective evaluation of 65 computed tomographic investigations on 27 patients with proven disseminated extrapulmonary tuberculosis showed no CT changes characteristic for tuberculosis, except for a higher density of tubercular abscesses. In the majority of cases the extent of tubercular manifestations could only be exactly established after the CT investigation. With the aid of this information together with the clinical course of the disease, the timing, type and extent of operative measures could be determined. Finally, in comparison with conventional X-ray and sonography, computed tomography has proved to be superior for control of therapeutic procedures.

Adult↗