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Effect of extra-alveolar period and storage media upon periodontal and pulpal healing after replantation of mature permanent incisors in monkeys.

The effect of extra-alveolar period and storage media upon periodontal and pulpal healing after replantation was studied in green Vervet monkeys (Cercopithecus aethiops). Mandibular lateral incisors were extracted. The extra-alveolar period before replantation was 0, 18, 30, 60, 90, and 120 min. The storage media for the extracted teeth were tap water, physiologic saline, saliva or dry storage. The animals were sacrificed 8 weeks after replantation and the replanted teeth were examined histometrically. The following histologic parameters were registered for each tooth: surface resorption, inflammatory resorption, replacement resorption (ankylosis), periapical inflammatory changes, the extent of vital pulp and downgrowth of pocket epithelium. A significant relationship was found between the frequency of root resorption, extra-alveolar period and storage medium. This was especially evident after dry storage. Surface resorption was found with approximately the same frequency irrespective of extra-alveolar period and storage media. Inflammatory root resorption was especially common after dry storage and was related to the length of the extra-alveolar period. Already after 30 min dry storage, this resorption type was very prominent. Teeth stored in tap water, saline or saliva showed about the same frequency of inflammatory resorption, which increased slightly with increased extra-alveolar periods. Replacement resorption showed a strong relationship to dry storage and became very prominent after 60 min. Replacement resorption was rarely found among teeth stored in saline or saliva; whereas it was significantly increased among teeth stored in tap water. It is concluded that saline and saliva offer good protection against root resorption during the extra-alveolar period.

Animals↗

Resorption of premolar roots by ectopic canines.

This case report describes an unusual phenomenon related to bilaterally displaced canines, where both upper lateral incisors were absent, but where the canines produced extensive root resorption of both upper first premolars, necessitating their removal.

Adolescent↗

Pathological changes related to long-term impaction of third molars. A radiographic study.

Pathological changes related to impacted 3rd molars (ITM) were studied in a radiographic investigation of 2128 randomly selected patients. In radiographs from 644 patients, 1211 ITM were noted. Pathological changes were observed in 25 of 477 (5.2%) maxillary ITM and in 59 of 734 (8%) mandibular ITM. A pathologically widened pericoronal space (indicating a dentigerous cyst) was observed in 5 of 477 maxillary and 43 of 734 mandibular ITM (p less than 0.001). Other pathologic changes observed were resorption of the 2nd molars (1% in the maxilla, 1.5% in the mandible) or loss of marginal bone on the distal aspect of the second molars (4% in the maxilla, 1% in the mandible). The risk of pathological sequelae because of ITM, apparently, is low. Prophylactic surgical removal should, therefore, be regarded with some reserve, particularly in view of the high frequency of deep impactions, with greater risk for surgical complications.

Adult↗

[Dentomaxillary destructions in oxalosis].

Oxalosis, a rare metabolic disorder, leads to excessive formation of oxalate and deposition of calcium oxalate crystals in the tissue. This leads to renal insufficiency with resulting secondary hyperparathyroidism and myelofibrosis. In a 27 year old female patient, extensive destruction of the maxilla, mandible and teeth was observed which has not yet been described and which led to the loss of all teeth.

Adult↗

Central odontogenic fibroma. A case report.

A case of central odontogenic fibroma is reported. The clinical, radiological and pathological features are discussed. It is of particular interest because of its maxillary location and the severe external root resorption associated with the tumour.

Adult↗

Ridge preservation following tooth extraction using a polylactide and polyglycolide sponge as space filler: a clinical and histological study in humans.

BACKGROUND: The placement of different graft materials and/or the use of occlusive membranes to cover the extraction socket entrance are techniques aimed at preserving/reducing alveolar ridge resorption. The use of grafting materials in fresh extraction sockets has, however, been questioned because particles of the grafted material have been found in alveolar sockets 6-9 months following their insertion. AIM: The aims of the study were to (i). evaluate whether alveolar ridge resorption following tooth extraction could be prevented or reduced by the application of a bioabsorbable polylactide-polyglycolide sponge used as a space filler, compared to natural healing by clot formation, and (ii). evaluate histologically the amount and quality of bone tissue formed in the sockets, 6 months after the use of the bioabsorbable material. MATERIAL AND METHODS: Thirty-six patients, undergoing periodontal therapy, participated in this study. All patients were scheduled for extraction of one or more compromised teeth. Following elevation of full-thickness flaps and extraction of teeth, measurements were taken to evaluate the distance between three landmarks (mesio-buccal, mid-buccal, disto-buccal) on individually prefabricated stents, and the alveolar crest. Twenty-six alveolar sockets (test) were filled with a bioabsorbable polylactide-polyglycolide acid sponge (Fisiograft), while 13 sockets (controls) were allowed to heal without any filling material. The flaps were sutured with no attempt to achieve primary closure of the surgical wound. Re-entry for implant surgery was performed 6 months following the extractions. Thirteen biopsies (10 test and three control sites) were harvested from the sites scheduled for implant placement. RESULTS: The clinical measurements at 6 months revealed, in the mesial-buccal site, a loss of bone height of 0.2 mm (1.4 SD) in the test and 0.6 mm (1.1 SD) in the controls; in the mid-buccal portion a gain of 1.3 mm (1.9 SD) in the test and a loss of 0.8 mm (1.6 SD) in the controls; and in the distal portion a loss of 0.1 mm (1.1 SD) in the test and of 0.8 (1.5 SD) mm in the controls. The biopsies harvested from the test sites revealed that the new bone formed at 6 months was mineralized, mature and well structured. Particles of the grafted material could not be identified in any of the 10 test biopsies. The bone formed in the control sites was also mature and well structured. CONCLUSION: The results of this study indicate that alveolar bone resorption following tooth extraction may be prevented or reduced by the use of a bioabsorbable synthetic sponge of polylactide-polyglycolide acid. The quality of bone formed seemed to be optimal for dental implant insertion.

Adult↗

Mucopolysaccharidase activity in traumatized human deciduous teeth undergoing accelerated resorption: isolation and characterization.

Mucopolysaccharidase activity was observed in traumatized human decidous teeth. Histochemical analysis of the periodontal ligaments from these teeth revealed a loss of film substrate metachromasia during incubation, indicating enzyme activity. Routine histology of these ligaments showed the presence of an inflammatory infiltrate throughout this tissue. Biochemical analysis of the ligaments revealed a 10-fold increase of enzyme activity when incubation time was increased from 1 to 8 h. When compared to the enzyme activity measured during physiologic resorption, activity was increased. This suggests that the presence of an inflammatory infiltrate not observed in the tissues undergoing physiologic resorption may be responsible for the rapid resorption seen in traumatized deciduous teeth.

Child↗