Stethoscope monitoring during anesthesia.
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The spermatic cord of five dogs were twisted 720 degrees. The animals then underwent both Doppler and isotope evaluations of their scrotums. Both modalities proved highly accurate in diagnosing acute testicular ischemia.
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The effects of intravenous nicardipine (10 mg) on some aspects of left ventricular function have been studied with a radioisotope method in 10 male patients in chronic heart failure (NYHA Class II and III). Blood pressure (mean +/- s.d.) fell from 133 +/- 26/86 +/- 11 mm Hg to 103 +/- 22/69 +/- 13. Heart rate rose from 67 +/- 9 beats per minute to 85 +/- 10. Left ventricular ejection fraction rose from 31 +/- 7% to 38 +/- 6% and relative cardiac output from 24 +/- 9 to 41 +/- 11 (P less than 0.001 in all cases). This suggests that nicardipine has a potent vasodilator effect which results in increased left ventricular pumping activity in patients with mild to moderate heart failure.
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