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Intensive care nursing requirements: resource allocation according to patient status.

Intensive care nursing allocation seemingly has been a negotiated solution to a never ending battle: an arbitrary nursing/patient ratio. To correct this deficit, a prospective study was proposed to quantitate the time duration of sufficient intensive care to match the severity of illness. A comprehensive list of all nursing actions was compiled and timed. Thereafter, frequencies were observed according to global classifications: serious, critical, or crisis. A simple classification system separates the hourly requirement: serious = 2:1 patient/nurse ratio, critical = 1.0:0.75 full time nursing, and crisis = 1.0:1.2 patient/nurse ratio (or single nurse requires assistance). The increased requirements are created by increased need for ICU skills: vital signs = 1 hour for serious patients, 4 hours for critical, and a maximum of 10 hours for crisis patients (90% crisis patients has pulmonary artery and arterial catheters). Other categories of increased nursing time reflect ventilatory support, increased number of continuous and intermittent medications, etc. Global assessment (serious, critical, or crisis patient status) can be quantitated in terms of nursing hours actually required. Objective, rational, and variable patient/nurse ratios can be easily and accurately achieved in this manner. Staffing requirements and allocation of positions can be objectively quantitated.

Humans↗

Kanamycin reveals the role played by glutamate receptors in shaping plant resource allocation.

Ionotropic glutamate receptors (iGluRs) play important roles in neurotransmission in animals. There is growing evidence that iGluRs also play important roles in plants. Using a chemical genetics approach, which combined a pH-homeostasis mutant of Arabidopsis thaliana (de-etiolated3), several different iGluR agonists, molecular modelling, and reporter gene expression in transgenic plants, we provide evidence that iGluR agonism can induce dramatic changes in plant development and metabolism. Systematic hypothesis testing revealed a signalling circuit that integrates amino acid and sugar signals to affect elongation growth and the deposition of carbon into starch and lignins. The data show that aminoglycoside antibiotics, such as kanamycin, and polyamines impinge upon this circuit. These findings provide a mechanism for the conversion of amino acid and sugar signals into an appropriate response at the gene expression level, and underline the similarities in iGluR agonism between animals and plants.

Aminoglycosides↗

Resource allocation.

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Health Care Rationing↗

Allocating resources to health authorities: results and policy implications of small area analysis of use of inpatient services.

A study designed to identify the principal determinants of use of inpatient facilities in NHS hospitals in England used the data and methods outlined in the previous paper. The model for the psychiatric sector contains mortality, self reported morbidity, and social variables indicating deprivation and the level of care at home. The non-acute model contains mortality and several socioeconomic variables. The models lay less weight on age than the current formula, and a national formula based on these models would, in the acute sector, redistribute resources to poorer areas compared with the current formula.

Health Care Rationing↗