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At least 505 records · Page 28Linked to original sources
PubMed1993

Lack of evidence of Chlamydia pneumoniae infection in infants with acute lower respiratory tract disease.

In order to determine whether there is serologic evidence of Chlamydia pneumoniae infection in young infants with acute lower respiratory tract infection, serum samples from 86 subjects aged less than 6 months were assayed for IgG and IgM antibodies to Chlamydia pneumoniae using a microimmunofluorescence method. Infants hospitalized in Toronto, Canada, were enrolled between 15 March 1991 and 15 March 1992. No patient had infection determined by the serologic results. IgG antibody was detected at low concentrations in 32 patients, with an inverse relationship between titer and chronological age. In our setting, Chlamydia pneumoniae does not appear to be an important lower respiratory pathogen in young infants.

Acute Disease↗
PubMed1993

[Effectiveness of relaxation groups in patients with chronic respiratory tract diseases].

In the long-term treatment of patients with chronic respiratory diseases, patient education contributes significantly towards improving the effectiveness of conventional drugs in the treatment of asthma-specific complaints and anxiety, as well as playing a role in improved disease coping. The aim of this study was to verify whether relaxation training programs undertaken subsequent to patient education may have an additional effect with regard to both medical and psychological variables. Relaxation training encompasses the basic exercises of autogenics, as well as exercises of functional relaxation. 49 patients participated in the relaxation group (22 male, 27 female). The mean age was 50.5 +/- 16.5 years. The control group used was made up of 37 patients with chronic respiratory diseases (17 male, 20 female) who had received asthma education, but no further therapeutic intervention. Prior to and immediately after the relaxation training, the following investigations were undertaken: lung function, patient diary, Spielberger anxiety scale, Giessen list of complaints (modified and augmented) and Ziegler coping questionnaire. The linear rating scale model was used for measuring changes. The following significant changes were observed in the relaxation group as compared with the control group: decrease of trait fear, alleviation of asthma-specific complaints and asthma attacks, decrease in sleep disturbances and in morning coughing urge, reduction in the required quantities of controlled-dosage aerosol, and a modified attitude toward the disease in the sense of an improved subjective coping competence.(ABSTRACT TRUNCATED AT 250 WORDS)

Adaptation, Psychological↗
PubMed1989

[Isolation of coronaviruses in cell culture from nasal swab samples of calves with respiratory tract diseases in the Federal Republic of Germany].

Coronavirus was isolated in HRT-18 tissue culture from nasal swabs of 4 from 15 calves showing respiratory symptoms. The strains showed cytopathic effects and could be identified as coronaviruses of bovine origin by their mouse erythrocyte agglutinating activity as well as serological specific hemagglutination inhibition and electron microscopical methods. This is the first report on the isolation of coronaviruses in tissue culture from the respiratory tract of calves in the FRG.

Animals↗
PubMed1988

[The importance of determining the cough reflex threshold in the diagnosis and treatment of respiratory tract diseases].

The cough reflex was studied in 91 patients classified into two groups: 54 patients with somatic pulmonary disease and marked bronchial hyperreactivity and 37 patients without bronchial hyperreactivity, some of the threatened with bronchial asthma, others with neurotic functional disorders only. The study shows that the stimulated cough reflex could be objectified in the patients, in the patients threatened with bronchial asthma and in some patients with functional disorders linked with neurosis.

Adolescent↗
PubMed1991

[The role of bronchoalveolar lavage in the diagnosis and therapy of recurrent respiratory tract diseases in children].

In 32 patients with relapsing bronchopneumonia, bronchiectasis, relapsing obstructive bronchitis and asthma bronchiale during aimed bronchoscopy bronchoalveolar lavage was made (BAL). The authors found typical cytological findings and deviations in the phosphatidyl choline level which is the main constituent of the pulmonary surfactant. The authors evaluated the importance of the surfactant for the proper function of the lungs and outlined possible therapeutic measures which by the action of some drugs will influence its formation.

Asthma↗
PubMed1991

[Chronic aspecific respiratory tract diseases in workers of pig-breeding farms].

To study chronic nonspecific respiratory diseases of people working in industrial swine confinement buildings, a cross sectional study was initiated. Based on history of diseases, clinical and parameters of ventilatory screening in 238 swine producers a frequency of chronic respiratory symptoms were found in 25.6%. The possible dependence on age, sex, smoking history, working conditions and duration of activity was investigated. The influence of professional and non professional factors had different intensity. The results of investigations of working conditions did not exceed the permitted maximal working place concentrations. So they could not prove the large frequency of respiratory diseases.

Age Factors↗
PubMed1997

[Levels of endothelin-I in bronchoalveolar fluid of patients with selected respiratory tract diseases].

UNLABELLED: Endothelin-I (ET-I) levels in BALF of symptomatic (n = 7) and asymptomatic (n = 10) asthmatic patients, sarcoidosis (n = 10), allergic alveolitis (n = 6) and healthy volunteers (n = 6) was evaluated. In all patients BALF level of endothelin-I was assessed by radioimmunoassay. We observed that patients with symptomatic asthma had more increased amounts of ET-I in BALF in comparison with asymptomatic asthmatics, patients with sarcoidosis, allergic alveolitis and control group. CONCLUSIONS: 1. Presence of ET-I in BALF indicates that this peptide is involved in the pathogenesis of bronchial asthma, sarcoidosis and allergic alveolitis. 2. Endothelin-I is involved in bronchial smooth muscle contraction.

Adult↗
PubMed1982

[Mucociliary clearance. Results in smokers, nonsmokers and patients with with respiratory tract diseases].

Using the modified radiographic teflon particle method the tracheal mucociliary clearance velocity (TCV) was found to be 13.5 +/- 4.5 mm/min in 36 normal probands. In 18 "normal" smokers there was a statistically slightly significant diminution when compared with 18 age-matched non-smokers (12.1 +/- 5.7 vs 15.0 +/- 4.2 mm/min; P less than 0.1). Some smokers with values below 7 mm/min could be "potential chronic bronchitis". Acute exposure to cigarette smoke led to a decrease of TCV from 19 to 8 in healthy smokers, and from 20 to 5 mm/min in nonsmokers. Whereas TCV was equally diminished to values between 0 and 5 mm/min in chronic bronchitis (n = 42), bronchial carcinoma (n = 8) and advanced bronchial asthma (n = 8), patients with bronchiectasis (n = 8) showed marked negative tracheal clearance of up to -25 mm/min.

Adult↗