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At least 505 records · Page 28Linked to original sources
PubMed1998

Long-term quality of life after breast cancer: comparison of 8-year survivors with population controls.

PURPOSE: Quality of life of breast cancer survivors 8 years after diagnosis was compared with that among similarly aged women who had never confronted cancer (controls). METHODS: Survivors of a consecutive series of 227 breast cancer patients first treated in 1984 were approached for this study. Random-digit dialing was used to identify controls with the same age and residential distribution as the survivors. Quality of life was assessed in terms of physical health, functional status, psychologic distress, and social functioning. RESULTS: Participation was obtained from 96% (n = 124) of 129 eligible survivors and 61% (n = 262) of 427 potentially eligible controls. Consistently smaller proportions of survivors reported positive quality-of-life outcomes compared with controls, but these differences were generally small and nonsignificant statistically. When limited to women who remained free of disease over the entire follow-up period (n = 98), survivors' quality of life was similar to that among controls, with the exception of arm problems and sexual satisfaction for those women who lived with a partner. In contrast, survivors who developed recurrence or new primary breast cancer (n = 26) experienced a worse quality of life in all domains except social functioning. CONCLUSION: In most domains and for women without further disease events after diagnosis, quality of life does not seem to be permanently and globally impaired by breast cancer. Consequently, breast cancer survivors who remain free of disease probably do not need organized late psychosocial follow-up to improve quality of life. However, arm problems and sexuality are two areas in which additional effort may be still needed to improve quality of life of long-term survivors.

Activities of Daily Living↗
PubMed1983

Selection for body weight at eight weeks of age in dwarf and normal meat-type chickens originating from a common control population background.

A study was conducted to evaluate responses to selection for 8-week body weight in normal and dwarf meat-type broiler lines originating from the same nonselected randombred population. Following three generations of selection, normal and dwarf dams were mated to males from a commercial broiler stock to compare strain cross performance of progeny from the two dam groups. The mean realized heritabilities across four generations for 8-week body weight, estimated by dividing the cumulative responses by the cumulative selection differentials, were .69 for normal lines and .59 for dwarf lines. Realized estimates from regression of population means on cumulative selection differentials were .78 +/- .10 and .74 +/- .02 for normal lines and .70 +/- .14 and .59 +/- .19 for dwarf lines. Although these estimates were not significantly different, realized heritabilities were consistently greater in normal than in dwarf lines across generations. The smaller heritability estimates observed in dwarf lines were compensated for by larger selection intensities (i), which resulted in similar selection responses in 8-week body weight for normal and dwarf genotypes. The fertility of normal and dwarf females mated to commercial broiler males was identical. However, the hatchability of fertile eggs was approximately 10% higher for dwarfs than for normal females. Body weights (8-week) of male progeny from dwarf dams mated to commercial males were 3% smaller than comparable males from normal dams. There were no differences between 8-week body weights of female progeny from normal and dwarf dams mated to commercial males.

Animals↗
PubMed2003

Analysis of articulation of fricative praealveolar sibilant "S" in control population.

Defective pronunciation of one or more mother language phones, i.e. dyslalia, represents the most frequent speech impairment both in children and adult people. Cases of persisting speech disorder need professional approach and help. The aim of the study was to obtain a model of physiological articulation of the sibilant "s" in children. The method of FFT spectral analysis was made use of. Results will serve for further use in evaluation of speech impairment.

Articulation Disorders↗