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At least 505 records · Page 28Linked to original sources
PubMed1970

Schedule-induced polydipsia: are response-dependent schedules a limiting condition?

The collateral water intake of albino rats was measured when the inter-pellet intervals in fixed-ratio and fixed-time schedules were equated. Fixed-ratio and fixed-time inter-pellet intervals were equated by dividing the average fixed-ratio session time of each subject by 150 (food pellets). The average inter-pellet interval obtained then defined the subsequent fixed-time schedule for each individual subject. Shifts to fixed-time schedules followed the completion of each fixed-ratio 20, 40, and 80 schedule. This procedure permitted an assessment of the extent to which excessive collateral drinking was associated with inter-pellet interval length or adventitious food reinforcement. For both the fixed-ratio and fixed-time schedules, drinking progressively increased as a function of increasing the duration of the inter-pellet interval and was a post-pellet event under the control of variables other than adventitious food reinforcement.

Journal Article↗
PubMed1970

Polydipsia induced in the rat by a second-order schedule.

Drinking was studied in rats pressing a bar on a second-order schedule in which every third completion of a 1-min fixed interval was followed by food presentation. A brief flash of light signaled the completion of each fixed-interval component. The rats drank not only after the food presentations but also after presentations of the light flash alone. A high rate of steady drinking followed intervals terminated by a food presentation. Drinking that followed intervals terminated by a light flash alone was of comparable rate, but characteristically interrupted by bar pressing. When 250-mg food pellets were used instead of 45-mg pellets, both drinking and bar-pressing rates increased substantially.

Animals↗
PubMed1974

Ubiquity of schedule-induced polydipsia.

Spaced feeding of individual food pellets to food-deprived rats induced excessive drinking after pellet delivery if water was continuously available. When access to water was restricted to a portion of the inter-pellet interval, and competition from food-reinforced bar pressing was removed, excessive drinking occurred whenever drinking was possible. This finding extends the generality of accounts of excessive behavior that implicate induction by apparently unrelated scheduling characteristics of the environment.

Animals↗
PubMed1974

Effects of lick-contingent timeout on schedule-induced polydipsia.

Rats bar pressing on a 1-min fixed-interval schedule for 45-mg food pellets became polydipsic when water was concurrently available. They were then exposed to conditions in which each lick on the drinking tube produced a timeout period during which the food-schedule lever was retracted and the fixed-interval timer either did or did not continue to operate. Licks occurring within a timeout period extended its duration. As the duration of the lick-initiated timeout period was increased logarithmically through four values from 10 sec to 80 sec, lick rates as well as water intake rates generally decreased for all three subjects. As timeout duration was progressively increased, the rate of licks occurring in the absense of, but producing, timeouts decreased for all three rats, whereas the rate of licks occurring in the presence of timeout periods remained essentially constant. Water-intake rates and, with one exception, lick rates were suppressed more by timeout periods during which the fixed-interval timer did not continue to operate. These results indicate that lick-contingent timeout from positive reinforcement reduces schedule-induced drinking, and this suppressive effect is greater when the timeout period necessarily increases the interreinforcement interval beyond its minimum duration than when it does not.

Animals↗
PubMed1976

Effects of haloperidol on schedule-induced polydipsia.

In dose-related amounts, the drug haloperidol attenuated schedule-induced drinking by rats prefed with 0.01-mg drug added to 0, 25, 50, 75 or all of 100 Noyes 45-mg pellets. Drug pellets also induced less drinking than did regular Noyes pellets by rats that obtained these pellets at 1-min intervals by bar pressing. Haloperidol also reduced bar pressing and, temporarily, rate of reinforcement. The results appeared not to be due to a general sedative effect of haloperidol but to its selective power to reduce angiotensin-induced drinking. Thus, schedule-induced drinking, which is abnormal in not causing satiation, is controllable by a drug that interferes with the renin-angiotensin hormone system thought to regulate normal drinking.

Administration, Oral↗
PubMed1977

Polydipsia induced in rats by second-order schedules of reinforcement.

Three rats were exposed to a second-order schedule in which fixed-interval components ended either with food or with a brief stimulus that was never paired with food. Food and the brief stimulus occurred in a random sequence (variable-ratio 2 overall schedule). Another three rats were exposed to a similar second-order schedule, the only difference being that the food or the stimulus was presented independently of operant behavior (fixed-time components). The three rats exposed to the fixed-interval components licked at a water spout after each food presentation. These rats also licked in the intervals after the brief stimulus. Although the discriminative properties of food and of the brief stimulus were identical in relation to subsequent reinforcement, licking after the stimulus was less than after food. The three rats exposed to the second-order schedules with fixed-time components also licked at the water spout after food, but these rats did not lick consistently after brief stimulus presentations.

Acoustic Stimulation↗
PubMed1978

Schedule-induced polydipsia in rats living in an operant environment.

The effect of variations in interreinforcement interval on the temporal and distributional relation between feeding and drinking was continuously monitored. Rats were housed continuously in an operant chamber in which water was freely available, but lever pressing was required to obtain food (45-mg pellets). Initially, pellets were delivered on a fixed-ratio 1 schedule of reinforcement, which was followed by testing on response-initiated fixed-interval 15-, 30-, and 60-second schedules. The total number of discrete, daily meals (a period in which several pellets were earned in succession) was slightly higher during the fixed-interval schedules than during the fixed-ratio 1, but there was no systematic effect of fixed-interval length on meal frequency. Total water consumption, in contrast, increased dramatically as the interval was lengthened: both subjects consumed two to three times as much water on the fixed-interval 60-second schedule as on the fixed-ratio 1. The increased water consumption was the result of an alteration in the distribution of drinking relative to eating. During the fixed-ratio 1 condition, drinking occurred infrequently following individual food pellets and represented the smallest percentage of total drinking; drinking occurred predominantly just before or after a meal. As the fixed interval was lengthened, however, the frequency of postpellet drinking gradually increased and eventually comprised the largest proportion of daily drinking.

Journal Article↗