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[Clinical use of capsular tension ring during phacoemulsification in subluxated lens].

OBJECTIVE: To investigate the safety of capsular tension ring implantation during phacoemul- sification in the subluxated lens. METHODS: Capsular tension ring was implanted in 13 cases (14 eyes) of subluxated lens after continuous curvilinear capsulorrhexis during phacoemulsification. The luxated area was ranged from one third to three quarters of a circle. The capsular tension ring was necessary to be fixated on sclera if the luxated area was larger than half-quarter of a circle. After the ring was implanted, phacoemulsification was performed and foldable intraocular lens (IOL) was implanted. RESULTS: The capsular tension ring was successfully implanted in 14 eyes, including 11 IOLs fixated in the bag and 3 in ciliary sulcus. IOL positions in 12 cases were normal, and in 2 eyes, had slight tilt. The most common intraoperative complication was the rupture of capsular bag, and secondly, the loss of vitreous body. CONCLUSION: Capsular tension ring implantation is safe in the patient of lens subluxation during phacoemulsification. It can prevent the IOL decentration and decrease the vitreoretinal complication.

Adolescent↗

[Tear film changes after phacoemulsification].

OBJECTIVE: To evaluate tear film changes after phacoemulsification. METHODS: This prospective randomized study involved 68 consecutive patients with age-related cataract (79 eyes) who underwent phacoemulsification. Tear break-up time, Schirmer I test (S I t) value, corneal fluorescein staining, tear film pattern by DR-1 tear interfermetry and the height of tear meniscus were measured preoperatively and 1 day and 2, 7, 14, 30, 180 days postoperatively. RESULTS: At 1 day and 2 days postoperatively, the mean tear break-up time reduced greatly, and the number of patients who showed III to V tear film pattern, the mean S I t value, the height of tear meniscus and fluorescein staining scores increased significantly (P < 0.001 for day 1, P < 0.005 for day 2). S I t value at 7 days postoperatively (P = 0.831) and the height of tear meniscus at 14 days returned to their preoperative values (P = 1.000). The tear break-up time, corneal fluorescein staining scores and the grades of tear film pattern all recovered at 30 days postoperatively (P > 0.05). At 30 days postoperatively, 19.3% of patients showed shorter tear break-up time and less S I t value than that of preoperative day. In addition, 1/9 of the patients with normal preoperative tear film experienced dry eye at 30 days postoperatively. The cases with tear break-up time < 10 seconds compared to patients with tear break-up time >/= 10 seconds were more easily to show tear instability postoperatively (relative risk 13.5, 8.25, 20.0, 39.0, 8.6, 3.9 at 1 day and 2, 7, 14, 30, 180 postoperative days, respectively). CONCLUSION: Phacoemulsification significantly alters the tear break-up time, S I t value, corneal fluorescein staining, tear film pattern and the height of tear meniscus. Some patients with normal tear film may experience dry eye after surgery. Patients with preexisting tear break-up time < 10 seconds are easily at risk of experiencing the tear film instability postoperatively.

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Phacoemulsification in patients with secondary glaucoma caused by uveitis.

PURPOSES: To evaluate the effect of phacoemulsification in the patients with uveitis, secondary glaucoma and complicated cataract. METHODS: Phacoemulsification and implantation of a foldable intraoucular len was performed in 12 patients(13 eyes) with uveitis, secondary glaucoma and complicated cataract. The complications, intraocular pressures (IOP), and visual acuity were observed postoperatively. RESULTS: No severe complication was found in the patients postoperatively or within the operation procedure. The visual acuity was improved after the operation (P < 0.05). The intraocular pressures and/or the number of antiglaucoma medications reduced in 3 months of the follow-up time. CONCLUSION: Phacoemulsification is the best way to treat the patients with secondary glaucoma and complicated cataract caused by uveitis.

Adult↗

[Phacoemulsification in patients with cataract and overfiltering bleb after antiglaucoma surgery].

PURPOSE: To evaluate the effect of phacoemulsification in patients with cataract, overfiltering bleb, and low-tension after antiglaucoma surgery. METHODS: Phacoemulsification and implantation of a foldable intraocular len was performed in six patients(7 eyes) with overfiltering bleb, low-tension, and cataract. The complications, blebs, intraocular pressures(IOP), and visual acuity were observed postoperatively. RESULTS: No severe complication was found. The overfiltering blebs constricted and their walls became thicker three months after the operation. The visual acuity and IOP were improved (P < 0.05). CONCLUSION: Phacoemulsification may be another way to treat the patients with cataract and overfiltering bleb, low-tension after antiglaucoma surgery.

Aged↗

Clinical observation of 126 cases of sutureless phacoemulsification with PMMA intraocular lens implantation.

OBJECTIVE: To observe the safety and effect of sutureless phacoemulsification with PMMA intraocular lens (IOL) implantation. METHODS: One-hundred and twenty-six cases (126 eyes) of sutureless phacoemulsification with PMMA intraocular lens (IOL) implantation were retrospectived and evaluated. The surgeries were performed through a limbal tunnel incision. PMMA IOLs with 5.5 mm or 6.0 mm in diameter were implanted. RESULTS: The follow-up was 3-20 months. Visual acuity of 0.5 or better was obtained in 120 cases (95.2%), and that of 1.0 or better was obtained in 89 cases (70.6%). Intra-operative complications included posterior capsule rupture in 9 cases (7.1%) and iris injury in 7 cases (5.6%). Postoperative complications included early corneal edema in 96 cases (76.2%), transient intraocular pressure elevation in 5 cases (4.3%), remnant of cortex in 1 case and leakage of incision in 1 case. All were properly managed with good results. CONCLUSION: Sutureless phacoemulsification with PMMA IOL implantation is safe even in grass-root hospitals where cataracts are harder.

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Preliminary observation of one-site combined trabeculectomy and phacoemulsification in the management of cataract patients with drug-controllable glaucoma.

PURPOSE: To evaluate the effect of one-site combined phacoemulsification and trabeculectomy in the management of cataract patients with drug-controllable glaucoma. METHODS: Twenty-four cases (25 eyes) of cataract patients with glaucoma whose intraocular pressure could be controlled by drugs were observed. All had undergone one-site combined phacoemulsification and trabeculectomy. Intraocular pressure and visual acuity were observed. RESULTS: The follow-up was 1-21 months. Postoperative visual acuity was 0.4-0.6 in 9 eyes, 0.7-0.9 in 7 eyes and 1.0 or better in 9 eyes. Postoperative intraocular pressure was 2.17 +/- 0.764 kPa (16.28 +/- 5.73 mmHg), 1.83 +/- 0.90 kPa (13.74 +/- 6.77 mmHg) lower than that before surgery (t = 11.89, P < 0.01). Only one eye needed one drug to control intraocular pressure after surgery. CONCLUSIONS: One-site combined phacoemulsification and trabeculectomy is a safe, effective and convenient technique for the management of cataract patients with drug-controllable glaucoma.

Aged↗

New management of malignant glaucoma by phacoemulsification with posterior chamber foldable intraocular lens implantation.

OBJECTIVE: To investigate the feasibility of phacoemulsification with posterior chamber foldable intraocular lens implantation in the management of malignant glaucoma. PATIENTS AND METHODS: Fourteen patients with malignant glaucoma diagnosed in the Department of Glaucoma were enrolled in the study. 12 patients developed malignant glaucoma after filtration surgery. 1 developed after peripheral iridectomy. 1 patient developed malignant glaucoma without any clear cause. Cataract phacoemulsification was performed. Posterior chamber intraocular foldable lens was implanted in 10 cases of patients. RESULTS: All 14 patients were cured with normal intraocular pressure, normal anterior chamber depth and increased visual acuity. CONCLUSION: Phacoemulsification with posterior chamber foldable intraocular lens implantation is a good alternative in treating malignant glaucoma.

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[Management of infectious endophthalmitis following phacoemulsification].

PURPOSE: To discuss the cause and management of infective endophthalmitis following phacoemulsification. METHODS: Anterior chamber irrigation with anterior chamber drug injection, postoperative systemic and topical antibiotic therapy as well as the use of topical mydriatic agent were applied to 5 of 3,850 eyes which showed endophthalmitis following phacoemulsification. RESULT: All the 5 eyes were saved from infective endophthalmitis. 1 to 5 eyes underwent vitrectomy, 4 of 5 eyes underwent anterior chamber irrigation (wash out). 4 of 5 eyes had satisfactory visual outcome. One of them had poor visual outcome. CONCLUSION: Preoperative contamination of the anterior chamber is the most common source for pathogenic agents responsible for endophthalmitis following phacoemulsification. Prompt anterior chamber irrigation (washout) with anterior chamber drug injection is one of the effective treatment.

Aged↗

New management of angle-closure glaucoma by phacoemulsification with foldable posterior chamber intraocular lens implantation.

OBJECTIVE: To investigate the management of angle-closure glaucoma by phacoemulsification with foldable posterior chamber intraocular lens (PC-IOL) implantation. DESIGN: Retrospective, noncontrolled interventional case series. PARTICIPANTS: In 36 eyes with angle-closure glaucoma (ACG), there were 18 eyes with primary acute angle-closure glaucoma (PACG), 14 eyes with primary chronic angle-closure glaucoma (PCCG), 3 eyes with secondary acute angle-closure glaucoma (SACG) and 1 eye with secondary chronic angle-closure glaucoma (SCCG). INTERVENTION: Phacoemulsification with posterior chamber intraocular lens implantation. MAIN OUTCOME MEASURES: Postoperative visual acuity, IOP, axial anterior chamber depth. RESULTS: After a mean postoperative follow-up time of 8.81 +/- 7.45 months, intraocular pressure was reduced from a preoperative mean of 23.81 +/- 17.84 mmHg to a postoperative mean of 12.54 +/- 4.73 mmHg (P = 0.001). Mean anterior chamber depth was 1.75 +/- 0.48 mm preoperatively and 2.29 +/- 0.38 mm postoperatively (P = 0.000). Best spectacle-corrected visual acuity in 36 eyes ranged from 0.01 to 0.7 (20/200 to 20/30) postoperatively, which was better than preoperative VA ranging from hand movement to 0.4 (20/50) (P = 0.000). CONCLUSION: Phacoemulsification with posterior chamber foldable intraocular lens implantation can be a good alternative in treating angle-closure glaucoma.

Aged↗

[The clinical application of topical aneathesia in phacoemulsification].

PURPOSE: To evaluate the effects of topical aneathesia in phacoemulsification. METHODS: 82 patients(91 eyes) with cataract in phacoemulsification were divided into two groups, topical aneathesia was used on the group of 40 patients(45 eyes); Regular local aneathesia was used on the other group of 42 patients(46 eyes). RESULTS: The preparatory time prior to operation in the topical aneathesia group was shorter than that in the regular local aneathesia group(P < 0.05). Eye-sight recovery of topical aneathesia groups was quicker than that of the other group (P < 0.01). There was no distinct difference of operation time and pain-killing effects between the 2 groups(P > 0.05). COUCLUSIONS: Topical aneathesia, safe, effective and easy to control, can be popularized in phacoemulsification.

Administration, Topical↗

[Phacoemulsification in white cataract].

OBJECTIVE: To evaluate the value and technique of Phacoemulsification in white cataract. METHODS: Ninty eyes of senile cataract were divided into two groups by the density of the nuclei. Different operative technique was done in two groups. RESULTS: The success rate of the continuous curvilinear capsulorhexis was 88.9%. Seventy five eyes have got the visual acuity over 0.5 on the first day after the operation. There was significant difference between two groups. The complications of operation were mild corneal edema and posterior capsule tear. CONCLUSIONS: It's difficult to complete the phacoemulsification of white cataract. The surgeons are required the skillful technique and experience. However, phacoemulsification is valuable in white cataract.

Adult↗

[Phacoemulsification in eyes with Fuchs' heterochromic iridocyclitis].

PURPOSE: To evaluate the effect and safety of phacoemulsification with intraocular lens (IOL) implantation in eyes with Fuchs' heterochromic iridocyclitis. METHODS: We reviewed the 13 patients (14 eyes) with heterochromic iridocyclitis who had phacoemulsification and IOL implantation. Intraoperative and postoperative complication was observed. RESULTS: Intraoperative complication included miosis and hemorrhage in anterior chamber. Postoperative complication were glaucoma and hyphemia. Best corrected postoperative visual acuity was 1.0 or better in 65% of eyes. CONCLUSION: Eyes with heterochromic iridocyclitis tolerated well to the phacoemulsification with IOL implantation.

Adult↗

An evaluation of topical and local anesthesia in phacoemulsification.

OBJECTIVE: To assess the comparative efficacy of topical and local anesthesia in phacoemulsification. MATERIAL AND METHODS: The medical records of 186 men and women between the ages of 45-85 years, who underwent elective cataract surgery by phacoemulsification technique, under the care of one surgeon, over a period of one year, from March 1999-March 2000 were reviewed. RESULTS: Of 186 patients who underwent small incision, self-healing phacoemulsification cataract surgery, 124 received topical and 62 local anesthesia. The most common cataract types were nuclear sclerosis. The duration of surgery with topical anesthesia was shorter. Sutures and eye padding were more frequently applied for procedures done under local anesthesia. Uncorrected visual acuity in the first post-op week was between 20/20-20/50 for 53.6% of the cases done under topical compared to 30.9% in local anesthesia. A similar trend was noted in the visual acuity one month post operatively. CONCLUSION: The uncorrected visual acuity improves faster and the duration of surgery is shorter when topical anesthesia is used.

Administration, Topical↗

Phacoemulsification in subluxated cataract.

PURPOSE: To evaluate the outcome of phacoemulsification in eyes with subluxated cataract. MATERIALS AND METHODS: This retrospective study comprised 22 eyes of 20 consecutive patients with subluxated cataracts of varying aetiology operated between March 1998 and March 2001. Detailed preoperative assessment included visual acuity (VA), slitlamp examination, presence of vitreous in anterior chamber extent of subluxation, intraocular pressure (IOP) and detailed fundus examination. Phacoemulsification was done to retain the natural bag support and all patients had acrylic foldable Acrysof IOL implantation either in-the-bag or by scleral fixation. Postoperative observations included best-corrected visual acuity (BCVA), IOP, pupillary reaction and the IOL position. RESULTS: The aetiology of the subluxation was traumatic in 11 patients and non-traumatic in 9 patients. Fifteen were males and 5 were females. Mean follow-up was 11.7 +/- 9.71 months (range 4-39). The average age was 39.15 +/- 16.33 (range 5-74). A 2-port anterior chamber vitrectomy was performed in 6 eyes (27.2%). Capsule tension ring (CTR) was implanted in 15 eyes (68.18%). Twelve eyes (54.5%) had in-the-bag implants, while 5 (22.72%) had scleral fixation. The remaining 5 eyes (22.72%) had one haptic in-the-bag and another sutured to sclera. No major intraoperative complications were noted. Twelve eyes (54.5%) had clinically and geometrically well centered IOLs while 9 eyes (40.9%) had geometrically decentered IOLs. One patient was lost to follow-up. Fifteen eyes (55.55%) had postoperative BCVA of 6/12 - 6/6 while 2 eyes (7.40%) had BCVA of 6/18. The remaining 4 eyes (14.81%) had less than 6/24 BCVA due to pre-existing posterior segment pathology. Postoperative complications included rise in IOP in 1 eye (4.54%), pupillary capture of the IOL optic in 2 eyes (9.09%); the same 2 eyes (9.09%) required redialing of IOL. One eye (4.54%) had to undergo refixation (one haptic was fixed to sclera) year after cataract surgery. Postoperative retinal detachment was noticed in one patient after a month of phacoemulsification. CONCLUSION: In subluxated cataracts it is essential to have appropriate parameters depending on the grade of cataract. This contributes to a safe and predictable outcome in subluxated cataract surgery.

Adolescent↗

Changes of blood aqueous barrier after phacoemulsification in rabbits.

PURPOSE: To evaluate the function and the morphological changes of the blood aqueous barrier (BAB) after phacoemulsification and to provide the physiological mechanism of BAB dysfunction. METHODS: Phacoemulsification was performed on 12 rabbit eyes. Aqueous humor was abstracted and the concentrations of aqueous humor protein were examined preoperatively and on postoperative days 1, 7, 14, 21, 30 with Lowry. After the iris and the ciliary body were removed from the rabbit eyes, we selected lanthanum nitrate as a tracer, then ultrastructural changes of BAB were investigated with transmission electron microscopy. RESULTS: Highly statistically significant differences (P < 0.05) were found between preoperative aqueous humor protein concentration and those measured on days 1, 7, 14, 21 and 30 after surgery. Under transmission electron microscopy, a part of the endothelial cells and BAB damaged as shown by the leakage of lanthanum tracing into intravessels through the broad space were observed. CONCLUSION: The results suggest that there is a blood aqueous barrier breakdown after phacoemulsification. The morphological basis of BAB damage is the reversible opening of tight junctions between endothelial cells.

Animals↗

Mechanism of corneal endothelial cells lesion during phacoemulsification and aspiration.

PURPOSE: To evaluate the proportions of corneal endothelial lesion caused by different factors during phacoemulsification and aspiration. METHODS: Fourteen cats (twenty eight eyes) were divided into four groups. The processed factors were ultrasonic power, lens extraction by phacoemulsification or not, and lens extraction using different levels of ultrasonic power. The density of central corneal endothelial cells was measured before and after operation. RESULTS: There is no statistic difference between pre-operation density and post-operation density for releasing ultrasonic power only without lens extraction group. But for the lens extraction group, there is difference in density of central corneal endothelial cells and the higher level of ultrasonic power, the more the central corneal endothelial cells density decreased through operation. CONCLUSION: The primary factor that causes corneal endothelial lesion during phacoemulsification and aspiration procedure is debris of lens nucleus, and the other factors cause the lesion of corneal endothelium in normal operations just in very small degree.

Animals↗

[Clinical studies of phacoemulsification combined with intraocular lens implantation in diabetics].

PURPOSE: To investigate the clinical results of phacoemulsification combined with intraocular lens implantation in diabetics. METHODS: All patients were divided into two groups, which there were 50 cases (61 eyes) with diabetics in the group A and 163 cases (174 eyes) without diabetics in the group B. All cases were treated with phacoemulsification combined with intraocular lens implantation. The level of the fasting blood-glucose in the diabetics must be controlled under 10 mmol/L by the dietotherapy, oral antihyperglycemic or insulin therapy before operation. The follow-up period was 1-28 months, average 8.6 months. RESULTS: The post-operative corrected visual acuities of 0.5 or better were achieved in 47 of 61 (77.1%) eyes in group A and in 140 of 174 (80.5%) eyes in group B, it was statistically no significant difference between the two groups (P > 0.05). The comparison between the two groups showed that there was no significant difference in the intra-operative or post-operative complications(P > 0.05). CONCLUSIONS: As long as the level of the blood surgar was controlled effectively, the treatment of phacoemulsification in diabetics was safe and effective as same as the patients without diabetics. It is very important to control the level of the blood sugar for maintaining the post-operative effect.

Aged↗

[Changes of lens capsule after phacoemulsification].

OBJECTIVE: To observe the changes in the lens capsule after phacoemulsification and its effects on the position of intraocular lens (IOL) and to demonstrate the best position of IOL in relation to the anterior capsule. METHODS: The present series comprised 141 eyes in 127 patients underwent phacoemulsification and foldable lens implantation with 5 mm continuous curvilinear capsulorhexis. The changes in the lens capsule and the position of IOL with dilated pupil were observed using slit lamp microscope 3 months after the operation. RESULTS: Capsular bag shrinkage and white Soemmering ring along the margin of capsulorhexis were observed in all cases. Three different kinds of relationship between anterior capsule opening and the IOL optic surface were found, including the non-capture (68 eyes), partial-capture (52 eyes) and total-capture (21 eyes) relationships. The incidence of central posterior capsule opacification (PCO) was significantly higher in the total-capture group (47.6%) than that in the non-capture (11.7%) and partial-capture (21.2%) groups (P < 0.01). IOL in well centered position was significantly higher in the non-capture (91.2%) and total-capture (81.0%) groups than that in the partial-capture group (42.3%) (P < 0.01). CONCLUSION: In the present study, various changes in the lens capsule were observed after phacoemulsification and foldable lens implantation. It is suggested that keeping the IOL in a non-capture position is a key point to avoid the occurrence of PCO and IOL decentration.

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