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PubMed1990

[Status of the venous part of the portal system in infectious-toxic shock in infants with acute pneumonia].

As many as 38 children aged 2 to 12 months suffering from acute pneumonia complicated by infectious-toxic shock manifested dilatation of the veins of portal circulation and deposition of a considerable blood volume, which was revealed by ultrasonic examination. The hemodynamic disorders were shown to play the leading part in the genesis of hepatomegaly, followed by hypoxic derangement of the hepatocyte. In infants, who are in a state of infectious-toxic shock, vascular decompensation of the liver is more pronounced and sets in earlier than parenchymatous. Administration of troxevasin (30 mg/kg a day) to the sick children promotes a more rapid elimination of venous dilatation in the system of portal circulation.

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