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Study of phosphoglucomutase polymorphism by isoelectric focusing: gene frequencies in the Gaddi tribe of Himachal Pradesh, India.

A total of 254 Rajputs and Brahmins of the Gaddi tribe from the regions of Kangra and Chamba in Himachal Pradesh, north-west India, were examined for red cell PGM1 phenotypes by isoelectric focusing (IEF). All the ten possible phenotypes from the four alleles of PGM1 described by IEF were found in this population. Comparison of gene frequencies in the present two ethnic groups and with the only other study available on Asians from London shows that IEF is another useful biochemical method for the study of population diversity.

Alleles↗

Polymorphism of phosphoglucomutase in cattle leucocytes.

By menas of starch gel electrophoresis the polymorphism of the phospoglucomutase isozymes PGM1 has been investigated in cattle leucocytes. The phenotypess and allele frequencies of PGM1 are demonstrated in a series of 106 complete and 221 incomplete families of "Deutsche Schwarzbunte". The segregation of the 327 daughters' phenotypes agree with the formal genetic model of 2 codominant autosomal alleles. The observed heterozygous PGM1 type is more frequent in mating types and progenies as expected under equilibrium.

Alleles↗