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Internalized homophobia in men: wanting in the first person singular, hating in the first person plural.

This paper focuses on the expression of internalized homophobia in men, arguing that the most powerful clinical use of this term depends upon its applicability to any man, without limitation to those whose primary object choice is homosexual. A number of dynamic situations are described to which the term might apply, elaborated by examples from contemporary culture and clinical practice. A central dynamic elucidated here is the move from an anxiety-ridden, first person singular voice to the promised safety of a first person plural voice--that is, from the dangerous position of "I want" to the more protected "we hate."

Adult↗

Biochemical and physiological parameters on the healthy skin surface of persons with candidal intertrigo and of persons with tinea cruris.

Biochemical and physiological tests were carried out on the skin surface of 20 patients with candidal intertrigo and 27 patients with tinea cruris. In all patients the test areas were free of efflorescences. The same tests were performed in 39 and 27 resectively healthy test persons of the same age and sex. The following striking findings came to light: 1. There was a significant decrease in the percentage amount of squalene in the skin surface lipids of the moniliasis group as compared with the control group. 2. There was a significant decrease in the reducing substances in the so called water solubles obtained with the phenol sulfuric acid method in the moniliasis group. The same results were obtained when only those moniliasis patients who were definitely not suffering from diabetes mellitus were taken into account. This is presumably a question of a reduction in the bound carbohydrates. 3. There were significantly more amino acids extractable from the skin surface of the tinea cruris patients than of the control persons. These results point to important predisposing factors for the susceptibility to candidal intertrigo and tinea cruris respectively.

Adolescent↗

Possible person-to-person transmission of Escherichia coli O111--associated hemolytic uremic syndrome.

Over a 3-month period, ten children (aged 1-13 years) from a 15-km radius in southern Picardy developed typical D+ hemolytic uremic syndrome (HUS). Polymerase chain reaction, using two pairs of verocytotoxin 1-(VT1) and VT2-specific oligonucleotide primers and an internal control was used to detect VT genes directly from stools samples. VT2 gene was detected in seven of nine patients' stools and in 5 of 14 contacts' stool samples. A VT2-producing Escherichia coli (VTEC) O111 was isolated from five of nine children's stools and in 3 adults' stools of the 14 tested. A retrospective case-control study was performed which showed a higher rate of absence in school A, where the first four cases were detected, compared with a control school. The odds ratio for the whole school was 2.77 (confidence interval 1.46-5.26), and 15 (confidence interval 2.54-115.6) if only the nursery classes were considered. A culture of all food samples from households was always negative for VTEC. A retrospective cohort study performed in 89% of children attending school A showed no linkage between food or drink and gastroenteritis. These findings emphasize the potential for person-to-person transmission of VT2-producing E. coli O111, since the only salient risk factor was close contact.

Adolescent↗

[Algorithm of graphic interactive presentation and automatic correction of a complex personality inventory (MMPI, Minnesota Multiphasic Personality Inventory)].

MMPI (Minnesota Multiphasic Personality Inventory) gives an evaluation of personality traits from one's positions relative to 550 items - short forms of the inventory may allow an estimate of reduced number of scales from a reduced number of items. This study describes the logical background of the selection and scoring of an arbitrarily defined short form of the MMPI. The use of the inventory via an interactive processor, much more effective than the commonly used item sets and manual scoring, is contributing to its development outside the clinical field.

Computers↗

Person-to-person transmission of Pseudomonas cepacia between patients with cystic fibrosis.

Ribotyping, a method of strain identification based on analysis of bacterial genomic restriction fragment length polymorphisms, was used to investigate the acquisition of Pseudomonas cepacia by a patient with cystic fibrosis. Analysis of isolates recovered from the index patient and his contacts showed person-to-person transmission of this opportunist organism. This documentation of the transmission of P cepacia from one cystic fibrosis patient to another suggests that measures to limit the acquisition of the pathogen by patients with cystic fibrosis may be worth while.

Adult↗

Person-to-person transmission of Brucella melitensis.

Human brucellosis is primarily an occupational hazard in the USA; in the Middle East and Africa ingestion of contaminated dairy products is an important route of infection. Whether human beings can become infected via person-to-person spread is uncertain. During an investigation of a commonsource, laboratory-associated outbreak due to Brucella melitensis, biotype 3, the wife of a microbiologist with serologically proven brucellosis became infected. Her blood isolate was indistinguishable from the epidemic strain. In the absence of other risk factors, we suggest that sexual intercourse is a possible means of transmission.

Brucella↗

Person-to-person transmission of cholera in a psychiatric hospital.

An outbreak of cholera caused by Vibrio cholerae O1, biotype el tor, serotype Ogawa, phage type 4, was reported in a psychiatric hospital in Singapore. A total of 74 inmates (18 symptomatic and 56 asymptomatic) were infected; two of them died. Extensive epidemiological investigations showed that the organism was not transmitted by contaminated food or water but through close person-to-person contact. Early recognition of the outbreak and prompt implementation of epidemic control measures comprising surveillance of diarrhoea, rectal swabbing of all asymptomatic inmates, isolation of those found to be infected, maintenance of a high standard of environmental sanitation and mass chemoprophylaxis with doxycycline, rapidly brought the outbreak under control.

Adult↗

The Draw-a-Person task in persons with mental retardation: what does it measure?

As a widely used, easy-to-administer, and nonthreatening task, the Draw-a-Person (DAP) holds particular promise as a nonverbal index of intelligence in persons with mental retardation. The DAPs of 108 adolescents and adults with mental retardation were reliably scored using Naglieri's cognitive and emotional disturbance scoring systems. Contrary to expectations, visual-motor skills emerged as the best predictor of DAP cognitive scores. Intelligence was correlated with DAP scores, but had considerably less predictive value than visual-motor skills. DAP emotional indicator scores were only modestly associated with social adaptation; even less support was found linking DAP emotional indicators to psychopathology. Findings point to considerable caution in using the DAP as an index of intelligence or as a screen for adjustment problems or specific psychopathology. Although related to intelligence, this popular task seems predominantly to measure visual-motor development in adults with mental retardation.

Adolescent↗

How is walking speed related to muscle strength? A study of healthy persons and persons with late effects of polio.

OBJECTIVES: To evaluate the relationship between walking speed and muscle strength in the lower extremities in healthy persons and in persons with late effects of polio and to compare the models for these relationships. DESIGN: Retrospective analysis. SETTING: University hospital department. PARTICIPANTS: An urban sample of 144 healthy men and women (age range, 40-79 y) and 234 (146 women, 88 men) subjects with late polio. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Muscle strength in the lower extremities was measured and combined into an index. Walking speed for spontaneous and maximal walking was measured. A nonlinear regression model was developed. RESULTS: Evidence was provided for the nonlinear relationship between walking speed and strength. A specific strength threshold could not be identified. The asymptote of this curve for maximal walking was 2.57 m/s in the healthy group and 2.02 m/s in the subjects with late effects of polio. A high body mass index (>25 kg/m2) lowered the asymptote. CONCLUSIONS: It is important to prevent strength decrease that approaches the critical level where a further reduction affects walking speed more evidently. The difference in the relationship between muscle strength and walking speed for the 2 groups studied may partly depend on biomechanic imbalance between muscle groups.

Adult↗

[Norovirus gastroenteritis outbreak by person-to-person transmission in a nursing home].

BACKGROUND AND OBJECTIVE: The aim of this study was to conduct an investigation into an outbreak of gastroenteritis among health workers and residents (with different grades of dependence) at a nursing home. PATIENTS AND METHOD: We detected an outbreak of gastroenteritis in a group of 52 health workers and 124 residents at a nursing home in Oliana, Lleida (Spain). A bidirectional prospective and retrospective cohort study was conducted into the consumption of water, food, grade of dependence (high, medium and low), and specific job. We studied the water supply and six food items. Faecal specimens from 30 patients were cultured and examined for Norovirus by polymerase chain reaction-reverse transcription. The possible implication of different factors associated with gastroenteritis was assessed by relative risk (RR) at 95% confidence intervals (CI). RESULTS: We interviewed 97% of the patients (172/176). The overall attack rate was 53.3% (92/172). The symptoms were: diarrhoea 68.5% (63/92), vomiting 64.1% (59/92), nausea 63.0% (58/92), fever 33.7% (31/92), abdominal pain 28.3% (26/92), and headache 14.1% (13/92). The epidemic curve highlighted transmission for 19 days. The risk factors associated with gastroenteritis were high (RR = 1.6; 95% CI, 1.0-2.6) and medium (RR = 2.8; 95% CI, 1.0-8.0) levels of dependence, health worker with high level of contact with residents (RR = 2.8; 95% CI, 1.1-7.3) and those doing cleaning work (RR = 2.8; 95% CI, 1.0-8.0). Bacterial cultures were negative for samples of food and water. Also, cultures were negative for bacteria in faecal samples but tests were positive for Norovirus in 12 faecal samples. CONCLUSIONS: We showed a Norovirus outbreak in a nursing home, person-to-person spread, associated to high and medium grades of dependence among residents, health worker with high level of contact with them and with those doing cleaning work.

Adult↗

Hospital outbreaks of cholera transmitted through close person-to-person contact.

Three hospital outbreaks of cholera which started in a children's infectious diseases ward in Dar es Salaam in 1977/78, 1981, and 1983 were controlled by bacteriological screening and isolation of infected patients, administration of antibacterial chemoprophylaxis to all at-risk patients and their accompanying relatives, and by reducing overcrowding. The outbreaks in 1981 and 1983 were caused by two distinct multiply antibiotic resistant E1 Tor Vibrio cholerae O1 strains. In these three outbreaks overcrowded conditions facilitated person-to-person transmission of cholera within the hospital. Cholera patients should be nursed separately and high standards of hospital hygiene should be maintained. This is one of the first reports of hospital outbreaks of cholera caused by multiply antibiotic resistant strains.

Adult↗

Theory of Mind in schizophrenia: first person vs third person perspective.

Patients suffering from schizophrenia have an impaired meta-representation also known as Theory of Mind (ToM). Moreover, the presence of delusions or other positive symptoms of schizophrenia has been correlated to poor ToM performances. Lack of insight is a common symptom of schizophrenia and can be considered a critical manifestation of impaired ToM abilities. In particular, the present study addresses the role of perspective ToM ability in schizophrenic patients. Thirty severely delusional schizophrenic patients completely lack insight when interviewed about their delusions. Seven subsequently gain insight about their mental state when perspective is shifted from the first person to third person. These data suggest that in some delusional schizophrenic patients, it may be possible to gain access to and modify their mental states.

Adult↗

The whole person in health care (with approaches from a perspective of mind-body medicine): a personal view.

This paper offers a brief mind-body view of: What the whole person is The four aspects of life: physical, emotional, mental, subtle energy states. The concept that health and wellbeing is analogous to developing musical harmony between the four aspects. Each aspect can be imagined as a musical note. When in balance the harmony between the notes is clear. When out of balance the effect is discordant. Ways that personal performance may be enhanced by the integration of these four aspects including self help approaches, mindful bodywork and energetic medicines. 'When we are whole, we shall be healed...' (Caroline Stevensen).

Burnout, Professional↗

Person-to-person transmission of Kingella kingae among day care center attendees.

Fifty Kingella kingae organisms, isolated from tonsillar cultures of day care center attendees during an 11-month period, and 60 isolates derived from epidemiologically unrelated individuals, including 19 isolates from respiratory carriers and 41 isolates from patients with invasive infections, were typed by immunoblotting, pulsed-field gel electrophoresis, and ribotyping. One strain, defined by unique immunoblotting, pulsed-field gel electrophoresis, and ribotyping patterns, represented 14 day care isolates (28%) and was frequently isolated during the first half of the follow-up period; a second strain represented 23 (46%) isolates and prevailed during the last 5 months. Children frequently carried the same strain continuously or intermittently for weeks or months, when it was replaced by a new strain. Epidemiologically unrelated organisms showed greater variability, and no strain represented >5% of isolates. The present results support person-to-person transmission of K. kingae among young children in the day care setting.

Carrier State↗

Cluster of cases of invasive aspergillosis in a transplant intensive care unit: evidence of person-to-person airborne transmission.

In October 1998, a patient developed deep surgical-site and organ-space infection with Aspergillus fumigatus 11 days after undergoing liver retransplantation; subsequently, 2 additional patients in the transplant intensive care unit had invasive pulmonary infection with A. fumigatus diagnosed. It was determined that debriding and dressing wounds infected with Aspergillus species may result in aerosolization of spores and airborne person-to-person transmission.

Aspergillosis↗

Use of personal protective equipment and operating room behaviors in four surgical subspecialties: personal protective equipment and behaviors in surgery.

OBJECTIVE: To evaluate Universal Precautions (UP) compliance in the operating room (OR). DESIGN: Prospective observational cohort. Trained observers recorded information about (1) personal protective equipment used by OR staff; (2) eyewear, glove, or gown breaks; (3) the nature of sharps transfers; (4) risk-taking behaviors of the OR staff; and (5) needlestick injuries and other blood and body-fluid exposures. SETTING: Barnes-Jewish Hospital, a 1,000-bed, tertiary-care hospital affiliated with Washington University School of Medicine, St Louis, Missouri. PARTICIPANTS: OR personnel in four surgical specialties (gynecologic, orthopedic, cardiothoracic, and general). Procedures eligible for the study were selected randomly. Hand surgery and procedures requiring no or a very small incision (eg, arthroscopy, laparoscopy) were excluded. RESULTS: A total of 597 healthcare workers' procedures were observed in 76 surgical cases (200 hours). Of the 597 healthcare workers, 32% wore regular glasses, and 24% used no eye protection. Scrub nurses and medical students were more likely than other healthcare workers to wear goggles. Only 28% of healthcare workers double gloved, with orthopedic surgery personnel being the most compliant. Sharps passages were not announced in 91% of the surgical procedures. In 65 cases (86%), sharps were adjusted manually. Three percutaneous and 14 cutaneous exposures occurred, for a total exposure rate of 22%. CONCLUSION: OR personnel had poor compliance with UP. Although there was significant variation in use of personal protective equipment between groups, the total exposure rate was high (22%), indicating the need for further training and reinforcement of UP to reduce occupational exposures.

Adolescent↗

A person to person hepatitis A outbreak.

A person to person outbreak of hepatitis A is described: 90 cases of hepatitis A occurred in a small town in Calabria, southern Italy; all cases were under 18 years of age with the highest age-specific incidence rate in the 6-10 year age group. Transmission was identified by tracing close contacts with other incubating or active cases; only eight out of 90 cases were not identified as having a very probable or possible contact with an infecting case. Transmission was high between family members leading to a secondary family attack rate of 51% in children under 16. An enteric disease educational campaign was carried out together with IgG and no cases of hepatitis A were reported in the two years following the investigation.

Adolescent↗

Personal access to sequence databases on personal computers.

A comprehensive package of software has been developed to access nucleic acid and protein sequence databases on stand-alone IBM personal computers. The software combines keyword search on the annotation fields of the data with pattern matching algorithms on the biological sequences. Sequences containing complex sites like promoters or kink sites can be identified as well as sequences that are similar to a query sequence. Protein sequences with particular patterns of amino acids such as hydrophobic regions can be identified as well. Considering the relatively inexpensive hard disks now available, personal computers have become a cost-effective alternative to mainframe processing for sequence databases.

Amino Acid Sequence↗