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Pharmacological features of masculine sexual behavior in an animal model of depression.

Neonatal treatment with clomipramine induces behavioral alterations during adulthood that resemble symptoms observed in human depression. Therefore, it has been proposed as an animal model of depression. Impairment of male sexual performance is one of the main effects of this treatment. Using this model of depression, we evaluated the effects of drugs that stimulate sexual performance by acting selectively on the adrenergic, serotonergic, or cholinergic system. Yohimbine, a selective antagonist of the alpha-2 receptors; 8-OH-DPAT, a selective agonist of the 5-HT1A receptors; and oxotremorine, a muscarinic agonist, were administered to male rats neonatally treated with clomipramine that showed sexual behavior impairments. Yohimbine and oxotremorine induced only a slight improvement of sexual deficiencies. 8-OH-DPAT not only restored sexual behavior to normal levels, but induced facilitation in most of the copulatory parameters. These results suggest that neonatal treatment with clomipramine induces sexual deficits acting mainly on the adrenergic and cholinergic systems, while the serotoninergic system seems to be preserved.

8-Hydroxy-2-(di-n-propylamino)tetralin↗

Multisensory regulation of maternal behavior and masculine sexual behavior: a revised view.

Frank Beach's view of the multisensory regulation in Norway rats of copulation in males (12) and of pup retrieval in females (23) is critically analyzed and revised in terms of Lashley's influence, Beach's other work, and current neurobiological knowledge. Beach's view was that no single sensory stimulus is essential to elicit these behaviors, but that all relevant stimuli available summate in the neocortex; consequently, (a) sexual "arousal" is increased in males, leading to copulation, and (b) the "efficiency," or likelihood, of retrieval is increased in postpartum mothers. The revised view is based on a component analysis in which each of these behaviors consists of a chain of motoric responses elicited by somatosensory stimulation. Distal stimuli emanating from the female or pups induce proximity by provoking orientation, attention and arousal; the meaning of these stimuli is largely learned by conditioned associations during the initial executions of the behavior, although odors may have a prepotent influence for some individuals. Stimuli are integrated in a multisensory manner by both subcortical and neocortical mechanisms. Generalizations concerning the reproductive behavior of other mammalian species are suggested.

Animals↗

Masculine sexual activity affects slow wave sleep in Golden hamsters.

The sleep pattern is modified by events occurring during wakefulness. In rats, it has been shown that male sexual behavior has a direct influence on sleeping patterns, increasing slow wave sleep (SWS) duration. On the other hand, the sexual behavior pattern of the male Golden hamster differs from the copulatory pattern of male rats. Male hamsters copulate faster and they do not display the motor inhibition observed in rats after each ejaculation. Moreover, close to exhaustion, hamsters display a behavioral pattern known as Long Intromission, which has been linked to an sexual inhibitory process. The present study was performed to determine the effects of male sexual activity on the sleep pattern in hamsters. Subjects were allowed to copulate for 30 and 60 min. In addition, the effect of locomotor activity was also assessed. The results show that male sexual behavior induced a significant increase of SWS II, with a reduction of wakefulness. No effect was observed on REM sleep. Locomotor activity produced only a slight effect on sleep. The results are discussed in terms of the similarities between the effects observed after sexual behavior on sleep in rats and hamsters, despite the substantial differences in the behavioral pattern.

Animals↗

Masculine somatotype and hirsuteness as determinants of sexual attractiveness to women.

Five questionnaire studies asked women to rate the attractiveness of outline drawings of male figures that varied in somatotype, body proportions, symmetry, and in distribution of trunk hair. In Study 1, back-posed figures of mesomorphic (muscular) somatotypes were rated as most attractive, followed by average, ectomorphic (slim), and endomorphic (heavily built) figures by both British and Sri Lankan women. In Study 2, computer morphing of somatotypes to produce an intergraded series resulted in a graded response in terms of perceived attractiveness which mirrored the findings of Study 1. In Study 3, back-posed figures were manipulated in order to change waist-to-hip ratios (WHR) and waist-to-shoulder ratios (WSR). A WHR of 0.8-0.9 and a WSR of 0.6 were rated as most attractive and these effects were more pronounced when modeling mesomorphic figures. In Study 4, symmetric figures of a mesomorphic somatotype were rated as less attractive than a normal (asymmetric) version of the same man. Study 5 showed that presence of trunk hair had a marked, positive effect upon women's ratings of attractiveness for both mesomorphic and endomorphic male figures. Women also judged figures with trunk hair as being older and they consistently rated endomorphic figures as being older than mesomorphs. These results are consistent with effects of sexual selection upon visual signals that advertise health, physical prowess, age, and underlying endocrine condition in the human male.

Adult↗