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Intussusception and leiomyosarcoma of the gastrointestinal tract in a pediatric patient. Case report and review of the literature.

Intestinal leiomyosarcoma is a rare tumor in infants and children; only 46 cases have been reported in the English literature. Presenting signs and symptoms include abdominal pain and gastrointestinal obstruction and bleeding. We describe a neonate with the unique presentation of ileocecal intussusception accompanying an ileal leiomyosarcoma. In contrast to adult patients, where intussusception is associated with smooth muscle tumors in 30% of cases, leiomyosarcoma and subsequent intussusception is rare in infancy and childhood. The overall prognosis for long-term survival is similar for both pediatric and adult patients with leiomyosarcoma of the intestinal tract, with a five-year survival in reported cases of 53% and 40%, respectively.

Humans↗

Comparison of absorbed radiation doses in barium and air enema reduction of intussusception: a phantom study.

OBJECTIVE: We assessed the relative radiation load in patients undergoing hydrostatic and pneumatic reduction of childhood intussusception. MATERIALS AND METHODS: In a phantom study we simulated two situations occurring during reduction of intussusception. The absorbed radiation dose was measured at several positions in the phantom using either barium sulphate (BaSO4) or air in the simulated reduction, combined with either automatic exposure control (AEC) or constant exposure rate (CER) at fluoroscopy. From these values the mean absorbed dose was calculated for different depth compartments within the phantom. RESULTS: In the barium study the mean absorbed dose averaged over the total irradiated volume was 14-23 % lower when CER was used instead of AEC; in the air study the dose was 35-43 % lower when AEC was used instead of CER. The combination of air and AEC provided the lowest mean absorbed dose in the tissue. The barium enema created a low-radiation zone, which might be utilized for protecting radiation sensitive tissue. CONCLUSION: The use of BaSO4 or air in reduction of intussusception requires the proper combination with CER and AEC, respectively, to minimize the radiation load to the patient; the lowest radiation load is obtained by using air and AEC.

Abdomen↗

Sonography of appendiceal intussusception.

A case in which appendiceal intussusception was diagnosed preoperatively by sonography is described. The sonographic finding of multiple concentric hypoechoic and hyperechoic rings was confirmed at laparotomy to be due to appendiceal intussusception. Demonstration of the sonographic coiled spring sign in the right lower quadrant should raise the possibility of appendiceal intussusception. The differential diagnosis is discussed.

Adult↗

Air intussusception reduction: "the winds of change".

AIR is an excellent example of the application of the scientific process to the treatment of pediatric disease. For more than 40 years, pediatric radiologists in North America were comfortable with hydrostatic enemas for the diagnosis and treatment of intussusception. Initial clinical trials in the 1980s suggested the efficacy of AIR. Subsequent clinical studies demonstrated that fluoroscopy time and radiation are less, accurate pressure measurements are possible, and reduction rates are higher with AIR than with hydrostatic techniques. Questions regarding safety and types of perforation were answered in the laboratory with an animal model. Moreover, this experimental work clarified issues regarding maximum pressures and the importance of the Valsalva maneuver during AIR. Experimental data has been transferred to the radiological treatment of childhood intussusception. The "winds of change", generated by clinical and basic research, have now swept across North America. More and more radiologists are performing AIR. Many of the pediatric radiologists who still doubt the efficacy of AIR have had no experience with the technique. Air insufflation is safe and effective for the diagnosis and treatment of intussusception in infants and children. It is replacing the hydrostatic enema in an ever-increasing number of institutions. AIR is quicker, safer, and more effective than hydrostatic enemas. If you are using AIR, I hope this overview will further improve the radiological care of your pediatric patients. If you are not using AIR, I hope that these personal observations will stimulate your interest. "Try it; you'll like it!"

Air↗

Value of sonography including color Doppler in the diagnosis and management of long standing intussusception.

15 cases of intussusception with presenting symptoms of more than 24 h duration were studied by sonography and Doppler. The aim of the study was to determine the validity of the sonographic criteria of peritonitis and bowel ischaemia in order to reduce the risk of colonic perforation and to increase confidence in achieving a successful hydrostatic reduction. The results were reviewed retrospectively and cases divided into 2 groups. Cases in group 1 were reducible by barium enema while those in group 2 required surgical intervention. Sonographic features of peritonitis were absent in all cases of group 1 and 3 cases of group 2. These 3 cases were reduced manually at surgery while the other 5 cases in group 2 with positive features of peritonitis required bowel resection. Blood flow was documented by colour flow Doppler in all cases except the 3 cases with gangrenous bowel in group 2. When sonographic features of peritonitis and loss of blood flow to the intussusception are present in late intussusception, surgical intervention is required. On the other hand, enema reduction should be pursued when such features are absent.

Child, Preschool↗

Air reduction of an intussusception caused by a pathologic lead point in an infant.

Lead points that are the cause of an ileocolic intussusception are rare in infants [1], as is successful reduction using barium [2]. Air reduction of an intussusception with a pathologic lead point has not been previously reported. We report a case of an infant with an ileocolic intussusception secondary to a duplication cyst that was successfully reduced with air. The pathologic lead point was recognized at the time of reduction and confirmed with water-soluble contrast. Air is both a diagnostic and therapeutic contrast agent.

Air↗

Internal rectal intussusception--fact or fancy?

PURPOSE: There is still considerable debate whether internal intussusception represents a functional disorder. We have reviewed our results in an effort to define its symptomatology and to assess defecography. METHODS: Rectopexy has been performed for internal intussusception in 37 patients. Eighteen had solitary rectal ulcer syndrome (SRUS), and 31 had anterior rectal wall prolapse. Defecography demonstrated anterior wall prolapse in 13, circular prolapse in 21, and no disorders in 3 patients. Pelvic floor function was normal. Follow-up varied from one to nine years. RESULTS: Twenty-six patients became asymptomatic. Anterior wall prolapses could not be palpated anymore. All SRUS lesions healed. Patients with SRUS (P < 0.001) or circular prolapse (P < 0.001) became significantly more asymptomatic. Results in patients with anterior rectal wall prolapse were significantly worse (P < 0.001). CONCLUSIONS: Internal intussusception is a distinct functional rectal disorder. Its symptomatology and findings during physical examination are aspecific. Characteristic defecographic features and presence of SRUS are indications for surgery, provided pelvic floor function during straining is normal.

Humans↗

Peutz-Jeghers syndrome manifesting complete intussusception of the appendix and associated with a focal cancer of the duodenum and a cystadenocarcinoma of the pancreas: report of a case.

The unusual occurrence of an "inside-out" appendix reported here is a case of complete intussusception of the appendix of a 45-year-old woman with Peutz-Jeghers syndrome in whom the diagnosis of intussusception was made preoperatively. At laparotomy, the lead point of intussusceptum was revealed to be a Peutz-Jeghers syndrome polyp of the appendix. There was also a cystic lesion in the pancreas, and subsequent distal pancreatectomy revealed a cystadenocarcinoma of the pancreas. Two jejunal Peutz-Jeghers syndrome polyps and two duodenal Peutz-Jeghers syndrome polyps were found via intraoperative endoscopies. The duodenal polyps were endoscopically removed, whereas a jejunal wedge resection was performed for the adjoining jejunal polyps. One of the two duodenal polyps possessed an adenocarcinoma focus. To our knowledge, this is the first report of complete intussusception of the appendix caused by a Peutz-Jeghers syndrome polyp.

Appendiceal Neoplasms↗

Internal rectal intussusception: results of surgical repair.

Twenty-four patients with obstructed defecation due to rectal intussusception diagnosed by defecography were treated with rectopexy either by the Wells technique (9 patients) or by Orr's operation (15 patients). After follow-up from one to eight years, defecography demonstrated disappearance of the intussusception in 22 patients. None of the patients were completely relieved of their symptoms. Nine (41 percent; 95 percent confidence limits: 21-64) were improved and 13 were unchanged (59 percent; 95 percent confidence limits: 36-79), with no difference between the two procedures. One patient with solitary rectal ulcer was improved, and the ulcer disappeared. Four patients with moderate preoperative incontinence became continent postoperatively, but obstructed defecation was only improved in two of these patients. It is concluded that rectal intussusception is probably a secondary phenomenon in patients with obstructed defecation and that a conservative attitude toward surgery should be adopted.

Adult↗

Malignant lymphoma in the ileocecal region causing intussusception.

A 67-year-old female was admitted with diarrhea. Preoperatively, we diagnosed intussusception due to malignant lymphoma in the ileocecal region by image and colonoscopic examinations. We resected the right hemicolon for the tumor, which was located mainly in the cecum, causing intussusception. The stenotic terminal ileum free of the tumor was invaginated within the cecum with infiltrating tumor, thus showing the appearance of an anthill. The growth of the tumor corresponded with Wood's constrictive type, in which intussusception rarely occurs.

Aged↗

Adult intussusception with autoamputation and preservation of bowel continuity.

We present a case of adult intussusception with autoamputation and preservation of bowel continuity. Our patient, a 65-year-old man, passed a 65-cm segment of large bowel per anus with spontaneous recovery and with a two-month follow-up free of symptoms secondary to the intussusception. Mesenteric ischemia secondary to angiography with distal embolization two weeks prior to the event may have been a precipitating factor in this unusual form of intussusception.

History, 19th Century↗

Ileocolic intussusception in an adult. A postoperative complication of appendectomy.

Two weeks after appendectomy a right hemicolectomy was performed on a 35-year-old man because of an ileocolic intussusception. The appendiceal stump was the leading point of the intussusception. Ileocolic intussusception is a very rare complication after appendectomy. The clinical symptoms, diagnostic features, and mode of treatment are discussed.

Adult↗

Intrauterine intussusception--a cause for ileal atresia.

A case of ileal atresia consequent to intrauterine intussusception is reported. The baby presented with features of neonatal intestinal obstruction but signs of peritonitis were absent. The intussusception was discovered on gross examination of distal atretic ileal segment. The case was managed successfully by resection and end to back anastomosis. This case is reported to highlight intrauterine intussusception as one of the causes of ileal atresia.

Humans↗

Ultrasound guided hydrostatic reduction in the management of intussusception.

OBJECTIVE: A case series study was conducted for two years from 01 June 2002 to 01 June 2004 to study the efficiency of ultrasound guided hydrostatic reduction in the management of intussusception in children. METHODS: A total of 25 patients who underwent the procedure were evaluated. All the patients were diagnosed by High Resolution Ultrasonography (HRUSG). Continuous monitoring of the progress of reduction during the procedure was done by HRUSG. 500-1000 ml (average 600 ml) of normal saline was used. RESULTS: 24 out of 25 (96%) intussusceptions were successfully reduced. Average time taken was 15 minutes. All the patients were reviewed after 24 hrs for recurrence. None of them showed recurrence within 24 hrs. No complications were observed. CONCLUSION: The study concludes that ultrasound guided hydrostatic reduction is a safe, simple and effective method for treatment of intussusception in children.

Administration, Rectal↗

Adult ileal intussusception: an unusual emergency condition.

Adult intussusception occurs infrequently and differs from the childhood condition in its presentation, cause, and treatment. Nonspecific symptoms can delay diagnosis; most cases are diagnosed at emergency laparotomy. Increased use of computed tomographic scanning to evaluate patients with abdominal pain can enhance reliable preoperative diagnosis. Treatment entails simple bowel resection in most cases. Reduction is controversial, especially in cases of colonic intussusception. This report describes the diagnosis and management of a case of adult ileal intussusception caused by an inflammatory fibroid polyp-a rare lesion of the gastrointestinal tract.

Fibrosis↗

Cecal duplications: a rare cause for secondary intussusception.

Duplications of the alimentary tract are rare congenital anomalies that may occur at any level from mouth to anus. While the oesophagus and the ileum are the most common sites, duplications of the colon are rare. Two cases of ileocolic intussusceptions in 8-month-old girl and 6-month-old boy who were admitted to our hospital with acute abdomen findings are presented. Intraoperatively, cecal cystic duplications leading intussusception were revealed. Intussusception is one of the most important surgical emergence in infancy and typically, it does not involve a lead point in childhood. Although duplication cyst may act as lead point, the review of literature reveals its rarity.

Abdomen, Acute↗

Post traumatic intussusception in an adult.

Intussusception is a rare cause of intestinal obstruction in adults. When seen most cases have identifiable pathology. Intussusception following blunt abdominal trauma is extremely rare. This report presents a case of double jejuno-jejunal intussusception in a patient who sustained such an injury. There was no other intra-abdominal abnormality and manual reduction resulted in a complete recovery. The coincidental discovery of Q-fever may be etiologically relevant.

Abdominal Injuries↗

Adult intussusception--need for en-bloc resection.

BACKGROUND: Adult intussusception is an uncommon surgical presentation AIMS: We report a case of adult intussusception, review the literature and discuss the optimal management. METHODS: We describe a woman who presented with severe abdominal pain and a large supra-umbilical mass. Ileocolic intussception was confirmed on CT, and a laparotomy and en-bloc resection were carried out. Postoperatively she made an uneventful recovery. CONCLUSION: Adult intussusception is a rare clinical presentation. En-bloc resection should be the surgical treatment of choice in the majority of cases due to the high percentage of malignant lead points.

Adenoma↗